Physicochemical properties and antimicrobial activity of calcium hydroxide pastes in association with other compounds

Detalhes bibliográficos
Autor(a) principal: Borges, Mariana Maciel Batista
Data de Publicação: 2021
Outros Autores: Frank, Mayara Conde, Zancan, Rafaela Fernandes, Tartari, Talita, Vivan, Rodrigo Ricci, Duarte, Marco Antonio Hungaro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian journal of oral sciences (Online)
Texto Completo: https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8662098
Resumo: Aim: This study aimed to evaluate the pH, Ca2+ release, solubility, and antimicrobial activity of calcium hydroxide (Ca(OH)2) pastes in association with different substances. Methods: Sixty acrylic teeth (n=10) were filled with pastes that associated Ca(OH)2 with the following substances: benzalkonium chloride 5% (G1) and 50% (G2) both in propylene glycol, arnica glycolic extract (G3), green tea glycolic extract (G4), Calen/PMCC™ (G5), and Calen™ (G6). In the group G1 to G4 were used 1g of Ca(OH)2 powder with 0,8g of vehicle. pH and Ca2+ release was measured after 7, 15, and 30 days. For solubility, micro-CT was used immediately and at the periods of 7, 15, and 30 days. For the antimicrobial analysis, a biofilm of E. faecalis was induced in vitro on bovine dentin discs. Live/dead viability dye and confocal scanning microscopy were used. Results: The highest pH values occurred on the first 7 days, and the G6, G1, G3, and G5 presented the highest pH values at this period (P <0.05). Ca2+ release was higher in all groups at 7 days, with the highest values observed in G1, G5, and G6. The volume of all pastes showed no significant difference in the intragroup analysis at 7 and 15 days (P <0.05). G1 and G2 showed the highest antimicrobial action (P <0.05). For the biovolume, there was difference between the G6 and the other groups (P >0.05) with G1 presenting the lowest values. Conclusion: Benzalkonium chloride 5% increases the antimicrobial action of the Ca(OH2), without impairs physicochemical properties.
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spelling Physicochemical properties and antimicrobial activity of calcium hydroxide pastes in association with other compoundsAnti-infective agentsBiofilmsCalcium hydroxideRoot canal filling materialsChemical phenomenaAim: This study aimed to evaluate the pH, Ca2+ release, solubility, and antimicrobial activity of calcium hydroxide (Ca(OH)2) pastes in association with different substances. Methods: Sixty acrylic teeth (n=10) were filled with pastes that associated Ca(OH)2 with the following substances: benzalkonium chloride 5% (G1) and 50% (G2) both in propylene glycol, arnica glycolic extract (G3), green tea glycolic extract (G4), Calen/PMCC™ (G5), and Calen™ (G6). In the group G1 to G4 were used 1g of Ca(OH)2 powder with 0,8g of vehicle. pH and Ca2+ release was measured after 7, 15, and 30 days. For solubility, micro-CT was used immediately and at the periods of 7, 15, and 30 days. For the antimicrobial analysis, a biofilm of E. faecalis was induced in vitro on bovine dentin discs. Live/dead viability dye and confocal scanning microscopy were used. Results: The highest pH values occurred on the first 7 days, and the G6, G1, G3, and G5 presented the highest pH values at this period (P <0.05). Ca2+ release was higher in all groups at 7 days, with the highest values observed in G1, G5, and G6. The volume of all pastes showed no significant difference in the intragroup analysis at 7 and 15 days (P <0.05). G1 and G2 showed the highest antimicrobial action (P <0.05). For the biovolume, there was difference between the G6 and the other groups (P >0.05) with G1 presenting the lowest values. Conclusion: Benzalkonium chloride 5% increases the antimicrobial action of the Ca(OH2), without impairs physicochemical properties.Universidade Estadual de Campinas2021-07-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/866209810.20396/bjos.v20i00.8662098Brazilian Journal of Oral Sciences; v. 20 (2021): Continuous Publication; e212098Brazilian Journal of Oral Sciences; Vol. 20 (2021): Continuous Publication; e2120981677-3225reponame:Brazilian journal of oral sciences (Online)instname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPenghttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8662098/27046Brazil; ContemporanyCopyright (c) 2021 Brazilian Journal of Oral Scienceshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBorges, Mariana Maciel Batista Frank, Mayara Conde Zancan, Rafaela FernandesTartari, Talita Vivan, Rodrigo RicciDuarte, Marco Antonio Hungaro 2021-07-19T19:32:12Zoai:ojs.periodicos.sbu.unicamp.br:article/8662098Revistahttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/PUBhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/oaibrjorals@fop.unicamp.br||brjorals@fop.unicamp.br1677-32251677-3217opendoar:2021-07-19T19:32:12Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)false
dc.title.none.fl_str_mv Physicochemical properties and antimicrobial activity of calcium hydroxide pastes in association with other compounds
title Physicochemical properties and antimicrobial activity of calcium hydroxide pastes in association with other compounds
spellingShingle Physicochemical properties and antimicrobial activity of calcium hydroxide pastes in association with other compounds
Borges, Mariana Maciel Batista
Anti-infective agents
Biofilms
Calcium hydroxide
Root canal filling materials
Chemical phenomena
title_short Physicochemical properties and antimicrobial activity of calcium hydroxide pastes in association with other compounds
title_full Physicochemical properties and antimicrobial activity of calcium hydroxide pastes in association with other compounds
title_fullStr Physicochemical properties and antimicrobial activity of calcium hydroxide pastes in association with other compounds
title_full_unstemmed Physicochemical properties and antimicrobial activity of calcium hydroxide pastes in association with other compounds
title_sort Physicochemical properties and antimicrobial activity of calcium hydroxide pastes in association with other compounds
author Borges, Mariana Maciel Batista
author_facet Borges, Mariana Maciel Batista
Frank, Mayara Conde
Zancan, Rafaela Fernandes
Tartari, Talita
Vivan, Rodrigo Ricci
Duarte, Marco Antonio Hungaro
author_role author
author2 Frank, Mayara Conde
Zancan, Rafaela Fernandes
Tartari, Talita
Vivan, Rodrigo Ricci
Duarte, Marco Antonio Hungaro
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Borges, Mariana Maciel Batista
Frank, Mayara Conde
Zancan, Rafaela Fernandes
Tartari, Talita
Vivan, Rodrigo Ricci
Duarte, Marco Antonio Hungaro
dc.subject.por.fl_str_mv Anti-infective agents
Biofilms
Calcium hydroxide
Root canal filling materials
Chemical phenomena
topic Anti-infective agents
Biofilms
Calcium hydroxide
Root canal filling materials
Chemical phenomena
description Aim: This study aimed to evaluate the pH, Ca2+ release, solubility, and antimicrobial activity of calcium hydroxide (Ca(OH)2) pastes in association with different substances. Methods: Sixty acrylic teeth (n=10) were filled with pastes that associated Ca(OH)2 with the following substances: benzalkonium chloride 5% (G1) and 50% (G2) both in propylene glycol, arnica glycolic extract (G3), green tea glycolic extract (G4), Calen/PMCC™ (G5), and Calen™ (G6). In the group G1 to G4 were used 1g of Ca(OH)2 powder with 0,8g of vehicle. pH and Ca2+ release was measured after 7, 15, and 30 days. For solubility, micro-CT was used immediately and at the periods of 7, 15, and 30 days. For the antimicrobial analysis, a biofilm of E. faecalis was induced in vitro on bovine dentin discs. Live/dead viability dye and confocal scanning microscopy were used. Results: The highest pH values occurred on the first 7 days, and the G6, G1, G3, and G5 presented the highest pH values at this period (P <0.05). Ca2+ release was higher in all groups at 7 days, with the highest values observed in G1, G5, and G6. The volume of all pastes showed no significant difference in the intragroup analysis at 7 and 15 days (P <0.05). G1 and G2 showed the highest antimicrobial action (P <0.05). For the biovolume, there was difference between the G6 and the other groups (P >0.05) with G1 presenting the lowest values. Conclusion: Benzalkonium chloride 5% increases the antimicrobial action of the Ca(OH2), without impairs physicochemical properties.
publishDate 2021
dc.date.none.fl_str_mv 2021-07-19
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/other
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8662098
10.20396/bjos.v20i00.8662098
url https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8662098
identifier_str_mv 10.20396/bjos.v20i00.8662098
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8662098/27046
dc.rights.driver.fl_str_mv Copyright (c) 2021 Brazilian Journal of Oral Sciences
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2021 Brazilian Journal of Oral Sciences
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv Brazil; Contemporany
dc.publisher.none.fl_str_mv Universidade Estadual de Campinas
publisher.none.fl_str_mv Universidade Estadual de Campinas
dc.source.none.fl_str_mv Brazilian Journal of Oral Sciences; v. 20 (2021): Continuous Publication; e212098
Brazilian Journal of Oral Sciences; Vol. 20 (2021): Continuous Publication; e212098
1677-3225
reponame:Brazilian journal of oral sciences (Online)
instname:Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP
instname_str Universidade Estadual de Campinas (UNICAMP)
instacron_str UNICAMP
institution UNICAMP
reponame_str Brazilian journal of oral sciences (Online)
collection Brazilian journal of oral sciences (Online)
repository.name.fl_str_mv Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)
repository.mail.fl_str_mv brjorals@fop.unicamp.br||brjorals@fop.unicamp.br
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