Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian journal of oral sciences (Online) |
Texto Completo: | https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8674006 |
Resumo: | Aim: The aim of this study was to investigate the impact of pretreatment with ethanolic solutions of caffeic acid phenethyl ester (CAPE) at varying concentrations on the dentin collagen matrix, specifically focusing on its biomodification potential. This was assessed through evaluations of the modulus of elasticity and changes in mass. Methods: Seventy dentin collagen matrices (demineralized sticks) were prepared to receive treatments with ethanolic solutions of CAPE at concentrations of 0.05%, 0.1%, 0.5%, or 2.5%, or with control treatment solutions (distilled water or ethanol) for one hour. The dentin matrices were evaluated for modulus of elasticity and mass before (baseline), immediately after treatment (immediately), and after storage in Simulated Body Fluid (SBF) for time intervals of 1 and 3 months. Results: Generalized linear models for repeated measures over time indicated no significant differences between groups (p=0.7530) or between different time points (p=0.4780) in terms of the modulus of elasticity. Regarding mass variation, no differences were observed in the time interval between 1 month and the immediate time (p=0.0935). However, at the 3-month mark compared to the immediate time, the 0.1% CAPE group exhibited less mass loss compared to the water group (p=0.0134). Conclusion: This study concludes that various concentrations of CAPE in an ethanolic solution did not affect the modulus of elasticity of dentin, suggesting that CAPE lacks biomodifying potential in this context. However, it was observed that 0.1% CAPE positively influenced the variation in mass over different evaluation time intervals. |
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oai:ojs.periodicos.sbu.unicamp.br:article/8674006 |
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UNICAMP-8 |
network_name_str |
Brazilian journal of oral sciences (Online) |
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|
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Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations Caffeic acidCollagenDentinEthanolAim: The aim of this study was to investigate the impact of pretreatment with ethanolic solutions of caffeic acid phenethyl ester (CAPE) at varying concentrations on the dentin collagen matrix, specifically focusing on its biomodification potential. This was assessed through evaluations of the modulus of elasticity and changes in mass. Methods: Seventy dentin collagen matrices (demineralized sticks) were prepared to receive treatments with ethanolic solutions of CAPE at concentrations of 0.05%, 0.1%, 0.5%, or 2.5%, or with control treatment solutions (distilled water or ethanol) for one hour. The dentin matrices were evaluated for modulus of elasticity and mass before (baseline), immediately after treatment (immediately), and after storage in Simulated Body Fluid (SBF) for time intervals of 1 and 3 months. Results: Generalized linear models for repeated measures over time indicated no significant differences between groups (p=0.7530) or between different time points (p=0.4780) in terms of the modulus of elasticity. Regarding mass variation, no differences were observed in the time interval between 1 month and the immediate time (p=0.0935). However, at the 3-month mark compared to the immediate time, the 0.1% CAPE group exhibited less mass loss compared to the water group (p=0.0134). Conclusion: This study concludes that various concentrations of CAPE in an ethanolic solution did not affect the modulus of elasticity of dentin, suggesting that CAPE lacks biomodifying potential in this context. However, it was observed that 0.1% CAPE positively influenced the variation in mass over different evaluation time intervals.Universidade Estadual de Campinas2024-05-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/otherapplication/pdfhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/867400610.20396/bjos.v23i00.8674006Brazilian Journal of Oral Sciences; Vol. 23 (2024): Continuous Publication; e244006Brazilian Journal of Oral Sciences; v. 23 (2024): Continuous Publication; e2440061677-3225reponame:Brazilian journal of oral sciences (Online)instname:Universidade Estadual de Campinas (UNICAMP)instacron:UNICAMPenghttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8674006/33892Brazil; ContemporanyCopyright (c) 2024 Aline Honorato Damázio, Rosanna Tarkany Basting, Enrico Coser Bridi, Fabiana Mantovani Gomes França, Flávia Lucisano Botelho do Amaral, Cecilia Pedroso Turssi, Waldemir Francisco Vieira Junior, Roberta Tarkany Bastinghttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessDamázio, Aline HonoratoBasting, Rosanna TarkanyBridi, Enrico CoserFrança, Fabiana Mantovani GomesAmaral, Flávia Lucisano Botelho doTurssi, Cecilia PedrosoVieira Junior, Waldemir FranciscoBasting, Roberta Tarkany2024-05-06T16:34:43Zoai:ojs.periodicos.sbu.unicamp.br:article/8674006Revistahttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/PUBhttps://periodicos.sbu.unicamp.br/ojs/index.php/bjos/oaibrjorals@fop.unicamp.br||brjorals@fop.unicamp.br1677-32251677-3217opendoar:2024-05-06T16:34:43Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP)false |
dc.title.none.fl_str_mv |
Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations |
title |
Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations |
spellingShingle |
Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations Damázio, Aline Honorato Caffeic acid Collagen Dentin Ethanol |
title_short |
Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations |
title_full |
Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations |
title_fullStr |
Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations |
title_full_unstemmed |
Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations |
title_sort |
Stability of dentin matrix treated with caffeic acid phenethyl ester at different concentrations |
author |
Damázio, Aline Honorato |
author_facet |
Damázio, Aline Honorato Basting, Rosanna Tarkany Bridi, Enrico Coser França, Fabiana Mantovani Gomes Amaral, Flávia Lucisano Botelho do Turssi, Cecilia Pedroso Vieira Junior, Waldemir Francisco Basting, Roberta Tarkany |
author_role |
author |
author2 |
Basting, Rosanna Tarkany Bridi, Enrico Coser França, Fabiana Mantovani Gomes Amaral, Flávia Lucisano Botelho do Turssi, Cecilia Pedroso Vieira Junior, Waldemir Francisco Basting, Roberta Tarkany |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Damázio, Aline Honorato Basting, Rosanna Tarkany Bridi, Enrico Coser França, Fabiana Mantovani Gomes Amaral, Flávia Lucisano Botelho do Turssi, Cecilia Pedroso Vieira Junior, Waldemir Francisco Basting, Roberta Tarkany |
dc.subject.por.fl_str_mv |
Caffeic acid Collagen Dentin Ethanol |
topic |
Caffeic acid Collagen Dentin Ethanol |
description |
Aim: The aim of this study was to investigate the impact of pretreatment with ethanolic solutions of caffeic acid phenethyl ester (CAPE) at varying concentrations on the dentin collagen matrix, specifically focusing on its biomodification potential. This was assessed through evaluations of the modulus of elasticity and changes in mass. Methods: Seventy dentin collagen matrices (demineralized sticks) were prepared to receive treatments with ethanolic solutions of CAPE at concentrations of 0.05%, 0.1%, 0.5%, or 2.5%, or with control treatment solutions (distilled water or ethanol) for one hour. The dentin matrices were evaluated for modulus of elasticity and mass before (baseline), immediately after treatment (immediately), and after storage in Simulated Body Fluid (SBF) for time intervals of 1 and 3 months. Results: Generalized linear models for repeated measures over time indicated no significant differences between groups (p=0.7530) or between different time points (p=0.4780) in terms of the modulus of elasticity. Regarding mass variation, no differences were observed in the time interval between 1 month and the immediate time (p=0.0935). However, at the 3-month mark compared to the immediate time, the 0.1% CAPE group exhibited less mass loss compared to the water group (p=0.0134). Conclusion: This study concludes that various concentrations of CAPE in an ethanolic solution did not affect the modulus of elasticity of dentin, suggesting that CAPE lacks biomodifying potential in this context. However, it was observed that 0.1% CAPE positively influenced the variation in mass over different evaluation time intervals. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-05-06 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/other |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8674006 10.20396/bjos.v23i00.8674006 |
url |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8674006 |
identifier_str_mv |
10.20396/bjos.v23i00.8674006 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.sbu.unicamp.br/ojs/index.php/bjos/article/view/8674006/33892 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.coverage.none.fl_str_mv |
Brazil; Contemporany |
dc.publisher.none.fl_str_mv |
Universidade Estadual de Campinas |
publisher.none.fl_str_mv |
Universidade Estadual de Campinas |
dc.source.none.fl_str_mv |
Brazilian Journal of Oral Sciences; Vol. 23 (2024): Continuous Publication; e244006 Brazilian Journal of Oral Sciences; v. 23 (2024): Continuous Publication; e244006 1677-3225 reponame:Brazilian journal of oral sciences (Online) instname:Universidade Estadual de Campinas (UNICAMP) instacron:UNICAMP |
instname_str |
Universidade Estadual de Campinas (UNICAMP) |
instacron_str |
UNICAMP |
institution |
UNICAMP |
reponame_str |
Brazilian journal of oral sciences (Online) |
collection |
Brazilian journal of oral sciences (Online) |
repository.name.fl_str_mv |
Brazilian journal of oral sciences (Online) - Universidade Estadual de Campinas (UNICAMP) |
repository.mail.fl_str_mv |
brjorals@fop.unicamp.br||brjorals@fop.unicamp.br |
_version_ |
1800216397618348032 |