Physiological changes in glucose uptake by GLUT-4 in Gestational Diabetes Mellitus

Detalhes bibliográficos
Autor(a) principal: Bisneta, Isabel Pereira da Silva
Data de Publicação: 2020
Outros Autores: Beltrão, Siméia da Silva Almeida, Lima, Felicson Leonardo Oliveira, Silva, Carlos Danilo Cardoso Matos, Silva, Marcus Vinicius Cardoso Matos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/4783
Resumo: This study aimed to identify the physiological changes that occur in the GLUT4 in glucose uptake in patients with gestational diabetes mellitus, which changes have resulted due to the increase of counterregulatory hormones insulin at physiological stress imposed by pregnancy and by predetermining factors that can be genetic and / or environmental factors, inflammatory mediators and insulin resistance. Given that all these metabolic changes interfere directly or indirectly in glucose uptake by GLUT-4, there was a literature review with descriptive, explanatory and qualitative approach about the changes suffered by this carrier in gestational diabetes mellitus. It is therefore concluded that metabolic changes suffered in DMG interfere directly in the expression and translocation of the GLUT-4 glucose transporter.
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spelling Physiological changes in glucose uptake by GLUT-4 in Gestational Diabetes MellitusCambios fisiológicos en la captación en glucosa por GLUT-4 en Diabetes Mellitus GestacionalAlterações fisiológicas na captação de glicose pelo GLUT-4 no Diabetes Mellitus GestacionalMetabolismGestational diabetesReceiversInsulin resistance.MetabolismoDiabetes gestacionalReceptores Resistencia a la insulina.MetabolismoDiabetes gestacionalReceptoresResistência à insulina.This study aimed to identify the physiological changes that occur in the GLUT4 in glucose uptake in patients with gestational diabetes mellitus, which changes have resulted due to the increase of counterregulatory hormones insulin at physiological stress imposed by pregnancy and by predetermining factors that can be genetic and / or environmental factors, inflammatory mediators and insulin resistance. Given that all these metabolic changes interfere directly or indirectly in glucose uptake by GLUT-4, there was a literature review with descriptive, explanatory and qualitative approach about the changes suffered by this carrier in gestational diabetes mellitus. It is therefore concluded that metabolic changes suffered in DMG interfere directly in the expression and translocation of the GLUT-4 glucose transporter.Este estudio tuvo como objetivo identificar los cambios fisiológicos que ocurren en GLUT-4 en la absorción de glucosa en pacientes con diabetes mellitus gestacional, cambios que resultan del aumento de las hormonas contrarreguladoras de insulina debido al estrés fisiológico impuesto por el embarazo y los factores predeterminados que pueden ser factores genéticos y / o ambientales, mediadores inflamatorios y resistencia a la insulina. Teniendo en cuenta que todos estos cambios metabólicos interfieren directa o indirectamente con la absorción de glucosa por GLUT-4, se realizó una revisión bibliográfica, con un carácter descriptivo, explicativo y con un enfoque cualitativo sobre los cambios sufridos por este portador en la diabetes mellitus gestacional. Por lo tanto, se concluyó que los cambios metabólicos sufridos en DMG interfieren directamente en la expresión y la translocación del transportador de glucosa GLUT-4.Esse estudo visou identificar as alterações fisiológicas que ocorrem no GLUT-4 na captação de glicose em pacientes com diabetes mellitus gestacional, alterações essas que resultam em decorrência do aumento dos hormônios contrarreguladores da insulina pelo estresse fisiológico imposto pela gravidez e pelos fatores predeterminantes que podem ser genéticos e/ou ambientais, mediadores inflamatórios e resistência à insulina. Tendo em vista que todas essas mudanças metabólicas interferem direta ou indiretamente na captação de glicose pelo GLUT-4, realizou-se uma revisão bibliográfica, com caráter descritivo, explicativo e com abordagem qualitativa sobre as alterações sofridas por esse transportador no diabetes mellitus gestacional. Concluiu-se portanto que, alterações metabólicas sofridas no DMG interferem diretamente na expressão e translocação do transportador de glicose GLUT-4.Research, Society and Development2020-06-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/478310.33448/rsd-v9i7.4783Research, Society and Development; Vol. 9 No. 7; e857974783Research, Society and Development; Vol. 9 Núm. 7; e857974783Research, Society and Development; v. 9 n. 7; e8579747832525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/4783/4284Copyright (c) 2020 Isabel Pereira da Silva Bisneta, Siméia da Silva Almeida Beltrão, Felicson Leonardo Oliveira Lima, Carlos Danilo Cardoso Matos Silva, Marcus Vinicius Cardoso Matos Silvainfo:eu-repo/semantics/openAccessBisneta, Isabel Pereira da SilvaBeltrão, Siméia da Silva AlmeidaLima, Felicson Leonardo OliveiraSilva, Carlos Danilo Cardoso MatosSilva, Marcus Vinicius Cardoso Matos2020-08-20T18:05:03Zoai:ojs.pkp.sfu.ca:article/4783Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:28:30.786020Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Physiological changes in glucose uptake by GLUT-4 in Gestational Diabetes Mellitus
Cambios fisiológicos en la captación en glucosa por GLUT-4 en Diabetes Mellitus Gestacional
Alterações fisiológicas na captação de glicose pelo GLUT-4 no Diabetes Mellitus Gestacional
title Physiological changes in glucose uptake by GLUT-4 in Gestational Diabetes Mellitus
spellingShingle Physiological changes in glucose uptake by GLUT-4 in Gestational Diabetes Mellitus
Bisneta, Isabel Pereira da Silva
Metabolism
Gestational diabetes
Receivers
Insulin resistance.
Metabolismo
Diabetes gestacional
Receptores Resistencia a la insulina.
Metabolismo
Diabetes gestacional
Receptores
Resistência à insulina.
title_short Physiological changes in glucose uptake by GLUT-4 in Gestational Diabetes Mellitus
title_full Physiological changes in glucose uptake by GLUT-4 in Gestational Diabetes Mellitus
title_fullStr Physiological changes in glucose uptake by GLUT-4 in Gestational Diabetes Mellitus
title_full_unstemmed Physiological changes in glucose uptake by GLUT-4 in Gestational Diabetes Mellitus
title_sort Physiological changes in glucose uptake by GLUT-4 in Gestational Diabetes Mellitus
author Bisneta, Isabel Pereira da Silva
author_facet Bisneta, Isabel Pereira da Silva
Beltrão, Siméia da Silva Almeida
Lima, Felicson Leonardo Oliveira
Silva, Carlos Danilo Cardoso Matos
Silva, Marcus Vinicius Cardoso Matos
author_role author
author2 Beltrão, Siméia da Silva Almeida
Lima, Felicson Leonardo Oliveira
Silva, Carlos Danilo Cardoso Matos
Silva, Marcus Vinicius Cardoso Matos
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Bisneta, Isabel Pereira da Silva
Beltrão, Siméia da Silva Almeida
Lima, Felicson Leonardo Oliveira
Silva, Carlos Danilo Cardoso Matos
Silva, Marcus Vinicius Cardoso Matos
dc.subject.por.fl_str_mv Metabolism
Gestational diabetes
Receivers
Insulin resistance.
Metabolismo
Diabetes gestacional
Receptores Resistencia a la insulina.
Metabolismo
Diabetes gestacional
Receptores
Resistência à insulina.
topic Metabolism
Gestational diabetes
Receivers
Insulin resistance.
Metabolismo
Diabetes gestacional
Receptores Resistencia a la insulina.
Metabolismo
Diabetes gestacional
Receptores
Resistência à insulina.
description This study aimed to identify the physiological changes that occur in the GLUT4 in glucose uptake in patients with gestational diabetes mellitus, which changes have resulted due to the increase of counterregulatory hormones insulin at physiological stress imposed by pregnancy and by predetermining factors that can be genetic and / or environmental factors, inflammatory mediators and insulin resistance. Given that all these metabolic changes interfere directly or indirectly in glucose uptake by GLUT-4, there was a literature review with descriptive, explanatory and qualitative approach about the changes suffered by this carrier in gestational diabetes mellitus. It is therefore concluded that metabolic changes suffered in DMG interfere directly in the expression and translocation of the GLUT-4 glucose transporter.
publishDate 2020
dc.date.none.fl_str_mv 2020-06-10
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/4783
10.33448/rsd-v9i7.4783
url https://rsdjournal.org/index.php/rsd/article/view/4783
identifier_str_mv 10.33448/rsd-v9i7.4783
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/4783/4284
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 7; e857974783
Research, Society and Development; Vol. 9 Núm. 7; e857974783
Research, Society and Development; v. 9 n. 7; e857974783
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052815763308544

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