Scientific evidence of guaco biological activity: literature review

Detalhes bibliográficos
Autor(a) principal: Santos, Thiago das Virgens
Data de Publicação: 2019
Outros Autores: Martins, Victor Hugo da Silva, Nascimento, Fernanda Ribeiro, Santos, Rita de Cassia Macêdo
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/1125
Resumo: Plants with potential biological activity in the organism have important applicability in the present day as soon as the use is present in the culture of which it was adhered by the ancestors. The mikania, better known as guaco is used for several pathological conditions, both for cases related to the respiratory system and anti-inflammatory functions in various organs. This work aims to review the literature on the pharmacological effects of Mikania and to know the most used species. In studies done, it was verified that Mikania have several pharmacological effects, with antibacterial in dental infections, anti-hemorrhagic in cases of snakebite, anti-nociceptive with opioid-like actions, anti-inflammatory and antipyretic, useful in cases such as dengue. And this is due to its chemical constitution, since it holds a concentration of important active substances, especially coumarins. It is evident that secondary metabolites have biological activities in the body, with desired effects. M. glomerata was the most searched with positive results against tests. More effort is needed in the evaluation of compounds that can be used by society in the form of drugs with minimal side effects.
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spelling Scientific evidence of guaco biological activity: literature reviewEvidencias científicas de la actividad biológica del guaco: revisión de literaturaEvidências científicas da atividade biológica do guaco: revisão de literaturaMedicinal PlantsGuacoPopular culture.Plantas MedicinaisGuacoCultura Popular.SeparadasPorPonto e vírgula.Plants with potential biological activity in the organism have important applicability in the present day as soon as the use is present in the culture of which it was adhered by the ancestors. The mikania, better known as guaco is used for several pathological conditions, both for cases related to the respiratory system and anti-inflammatory functions in various organs. This work aims to review the literature on the pharmacological effects of Mikania and to know the most used species. In studies done, it was verified that Mikania have several pharmacological effects, with antibacterial in dental infections, anti-hemorrhagic in cases of snakebite, anti-nociceptive with opioid-like actions, anti-inflammatory and antipyretic, useful in cases such as dengue. And this is due to its chemical constitution, since it holds a concentration of important active substances, especially coumarins. It is evident that secondary metabolites have biological activities in the body, with desired effects. M. glomerata was the most searched with positive results against tests. More effort is needed in the evaluation of compounds that can be used by society in the form of drugs with minimal side effects.Las plantas con potencial actividad biológica en el organismo, tienen importantes aplicabilidades en los días actuales, tan pronto como el uso se hace presente en la cultura de la cual, fue adherida por los antepasados. La mikania, más conocida como guaco, se utiliza para diversas condiciones patológicas, tanto para casos relacionados al aparato respiratorio como con funciones anti-inflamatorias en varios órganos. El trabajo tiene como objetivo hacer una revisión de literatura acerca de los efectos farmacológicos de Mikania y conocer la especie más utilizada. En estudios realizados, verificó que Mikania posee diversos efectos farmacológicos, con antibacteriana en infecciones dentales, anti-hemorrágico en los casos de picadura por serpientes, anti-nociceptivo con acciones similares a opioides, anti-inflamatorio y antipirético, con utilidad en casos como dengue. Y eso es debido a su constitución química, ya que tiene una concentración de sustancias activas importantes, en especial las cumarinas. Es evidente que los metabolitos secundarios poseen actividades biológicas en el organismo, con efectos deseados. La M. glomerata fue la más investigada con resultados positivos frente a las pruebas. Siendo necesario más compromiso en la evaluación de compuestos que puedan ser utilizados por la sociedad en forma de fármacos con el mínimo de efectos colaterales.As plantas com potencial atividade biológica no organismo, tem importantes aplicabilidades atualmente, logo que o uso se faz presente na cultura da qual, foi aderida pelos antepassados. A mikania, mais conhecida como guaco é utilizado para diversas condições patológicas, tanto para casos relacionados ao aparelho respiratório como funções anti-inflamatórias em vários orgãos. O trabalho objetiva fazer uma revisão de literatura acerca dos efeitos farmacológicos da Mikania e conhecer a espécie mais utilizada. Em estudos feitos, verificou que a Mikania possui diversos efeitos farmacológicos, com antibacteriana em infecções dentárias, anti-hemorrágico nos casos de picada por serpentes, anti-nociceptivo com ações similares a opioides, anti-inflamatório e antipirético, com utilidade em casos como dengue. E isso é devido a sua constituição química, já que detém uma concentração de substancias ativas importantes, em especial as cumarinas. É evidente que metabólitos secundários possuem atividades biológica no organismo, com efeitos desejados. A M. glomerata foi a mais pesquisada com resultados positivos frente a testes. Sendo necessário mais empenho na avaliação de compostos que possam ser utilizados pela sociedade em forma de fármacos com o mínimo de efeitos colaterais.Research, Society and Development2019-05-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/112510.33448/rsd-v8i7.1125Research, Society and Development; Vol. 8 No. 7; e22871125Research, Society and Development; Vol. 8 Núm. 7; e22871125Research, Society and Development; v. 8 n. 7; e228711252525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/1125/931https://rsdjournal.org/index.php/rsd/article/view/1125/4556Copyright (c) 2019 Thiago das Virgens Santosinfo:eu-repo/semantics/openAccessSantos, Thiago das VirgensMartins, Victor Hugo da SilvaNascimento, Fernanda RibeiroSantos, Rita de Cassia Macêdo2020-06-26T21:20:30Zoai:ojs.pkp.sfu.ca:article/1125Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:26:17.410269Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Scientific evidence of guaco biological activity: literature review
Evidencias científicas de la actividad biológica del guaco: revisión de literatura
Evidências científicas da atividade biológica do guaco: revisão de literatura
title Scientific evidence of guaco biological activity: literature review
spellingShingle Scientific evidence of guaco biological activity: literature review
Santos, Thiago das Virgens
Medicinal Plants
Guaco
Popular culture.
Plantas Medicinais
Guaco
Cultura Popular.
Separadas
Por
Ponto e vírgula.
title_short Scientific evidence of guaco biological activity: literature review
title_full Scientific evidence of guaco biological activity: literature review
title_fullStr Scientific evidence of guaco biological activity: literature review
title_full_unstemmed Scientific evidence of guaco biological activity: literature review
title_sort Scientific evidence of guaco biological activity: literature review
author Santos, Thiago das Virgens
author_facet Santos, Thiago das Virgens
Martins, Victor Hugo da Silva
Nascimento, Fernanda Ribeiro
Santos, Rita de Cassia Macêdo
author_role author
author2 Martins, Victor Hugo da Silva
Nascimento, Fernanda Ribeiro
Santos, Rita de Cassia Macêdo
author2_role author
author
author
dc.contributor.author.fl_str_mv Santos, Thiago das Virgens
Martins, Victor Hugo da Silva
Nascimento, Fernanda Ribeiro
Santos, Rita de Cassia Macêdo
dc.subject.por.fl_str_mv Medicinal Plants
Guaco
Popular culture.
Plantas Medicinais
Guaco
Cultura Popular.
Separadas
Por
Ponto e vírgula.
topic Medicinal Plants
Guaco
Popular culture.
Plantas Medicinais
Guaco
Cultura Popular.
Separadas
Por
Ponto e vírgula.
description Plants with potential biological activity in the organism have important applicability in the present day as soon as the use is present in the culture of which it was adhered by the ancestors. The mikania, better known as guaco is used for several pathological conditions, both for cases related to the respiratory system and anti-inflammatory functions in various organs. This work aims to review the literature on the pharmacological effects of Mikania and to know the most used species. In studies done, it was verified that Mikania have several pharmacological effects, with antibacterial in dental infections, anti-hemorrhagic in cases of snakebite, anti-nociceptive with opioid-like actions, anti-inflammatory and antipyretic, useful in cases such as dengue. And this is due to its chemical constitution, since it holds a concentration of important active substances, especially coumarins. It is evident that secondary metabolites have biological activities in the body, with desired effects. M. glomerata was the most searched with positive results against tests. More effort is needed in the evaluation of compounds that can be used by society in the form of drugs with minimal side effects.
publishDate 2019
dc.date.none.fl_str_mv 2019-05-16
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/1125
10.33448/rsd-v8i7.1125
url https://rsdjournal.org/index.php/rsd/article/view/1125
identifier_str_mv 10.33448/rsd-v8i7.1125
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/1125/931
https://rsdjournal.org/index.php/rsd/article/view/1125/4556
dc.rights.driver.fl_str_mv Copyright (c) 2019 Thiago das Virgens Santos
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2019 Thiago das Virgens Santos
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 8 No. 7; e22871125
Research, Society and Development; Vol. 8 Núm. 7; e22871125
Research, Society and Development; v. 8 n. 7; e22871125
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052643409920000

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