The importance of microbiological quality control in phytotherapy products and medicinal plants

Detalhes bibliográficos
Autor(a) principal: Carmo, Juliana dos Santos
Data de Publicação: 2022
Outros Autores: Nogueira, Joseli Maria da Rocha, Silva, Líllian Oliveira Pereira da
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/33001
Resumo: Phytotherapeutic drugs and medicinal plants have been used to treat diseases for thousands of years and the expansion of their use has increased the need for a more rigorous microbiological quality control, since microbial contamination can affect the quality of the product and the health of the individual. From this, the present study aimed to analyze different methodologies applied in the microbiological quality control of phytotherapics and medicinal plants, in order to highlight their importance. This is, therefore, a literature review, in which articles published between 2016 and 2022 were analyzed. More than half of the selected articles (55%) addressed Phytotherapeutic drugs or medicinal plants with high microbial contamination, which can cause changes chemical characteristics of plant metabolites, reducing their therapeutic efficacy and generating toxic substances, in addition to the risk of infections by potential pathogens, being extremely harmful to the patient. However, not all articles correctly followed the microbiological control recommended by the legislation, which shows the need to carry out rigorous microbiological quality control and the adequacy of procedures to current legislation, in order to guarantee greater quality, safety and effectiveness of the product that is delivered to the patient. In view of the above, it is considered that Phytotherapeutic drugs should be analyzed with the same rigor as synthetic medicines, in which microbiological control must occur at all stages of the production process, in order to minimize the risks of contamination in the product and, consequently, commercialize products suitable for human consumption.
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spelling The importance of microbiological quality control in phytotherapy products and medicinal plantsLa importancia del control de calidad microbiológica en productos de fitoterapia y plantas medicinalesA importância do controle de qualidade microbiológico em produtos fitoterápicos e plantas medicinaisControle de qualidadeMedicamento fitoterápicoMicrobiologiaPlantas medicinais.Quality controlPhytotherapeutic drugsMicrobiologyMedicinal plants.Control de calidadMedicamento fitoterápicoMicrobiologíaPlantas medicinales.Phytotherapeutic drugs and medicinal plants have been used to treat diseases for thousands of years and the expansion of their use has increased the need for a more rigorous microbiological quality control, since microbial contamination can affect the quality of the product and the health of the individual. From this, the present study aimed to analyze different methodologies applied in the microbiological quality control of phytotherapics and medicinal plants, in order to highlight their importance. This is, therefore, a literature review, in which articles published between 2016 and 2022 were analyzed. More than half of the selected articles (55%) addressed Phytotherapeutic drugs or medicinal plants with high microbial contamination, which can cause changes chemical characteristics of plant metabolites, reducing their therapeutic efficacy and generating toxic substances, in addition to the risk of infections by potential pathogens, being extremely harmful to the patient. However, not all articles correctly followed the microbiological control recommended by the legislation, which shows the need to carry out rigorous microbiological quality control and the adequacy of procedures to current legislation, in order to guarantee greater quality, safety and effectiveness of the product that is delivered to the patient. In view of the above, it is considered that Phytotherapeutic drugs should be analyzed with the same rigor as synthetic medicines, in which microbiological control must occur at all stages of the production process, in order to minimize the risks of contamination in the product and, consequently, commercialize products suitable for human consumption.Los fitoterápicos y las plantas medicinales se han utilizado para tratar enfermedades desde hace miles de años y la expansión de su uso ha aumentado la necesidad de un control de calidad microbiológico más riguroso, ya que la contaminación microbiana puede afectar la calidad del producto y la salud del ser humano. A partir de esto, el presente estudio tuvo como objetivo analizar diferentes metodologías aplicadas en el control de calidad microbiológico de fitoterápicos y plantas medicinales, con el fin de resaltar su importancia. Se trata, por tanto, de una revisión bibliográfica, en la que se analizaron artículos publicados entre 2016 y 2022. Más de la mitad de los artículos seleccionados (55%) abordaban fitoterápicos o plantas medicinales con alta contaminación microbiana, que pueden provocar cambios en las características de los metabolitos vegetales, reduciendo su eficacia terapéutica y generando sustancias tóxicas, además del riesgo de infecciones por potenciales patógenos, siendo extremadamente perjudicial para el paciente. Sin embargo, no todos los artículos siguieron correctamente el control microbiológico recomendado por la legislación, lo que pone de manifiesto la necesidad de realizar un riguroso control de calidad microbiológico y la adecuación de los procedimientos a la legislación vigente, con el fin de garantizar una mayor calidad, seguridad y eficacia del producto que se dispensa al paciente. En vista de lo anterior, se considera que los medicamentos fitoterápicos deben ser analizados con el mismo rigor que los medicamentos sintéticos, en los que el control microbiológico debe ocurrir en todas las etapas del proceso de producción, con el fin de minimizar los riesgos de contaminación en el producto final y, en consecuencia, comercializar productos aptos para el consumo humano.Fitoterápicos e plantas medicinais vem sendo utilizados para tratamento de doenças há milhares de anos e a expansão de sua utilização fez aumentar a necessidade de um controle de qualidade microbiológico mais rigoroso, uma vez que a contaminação microbiana pode afetar a qualidade do produto e a saúde do indivíduo. A partir disso, o presente estudo teve como objetivo analisar diferentes metodologias aplicadas no controle de qualidade microbiológico de fitoterápicos e plantas medicinais, a fim de destacar sua importância. Trata-se, portanto, de uma revisão da literatura, em que foram analisados artigos publicados entre 2016 e 2022. Mais da metade dos artigos selecionados (55%) abordaram fitoterápicos ou plantas medicinais com elevada contaminação microbiana, o que pode ocasionar alterações das características químicas dos metabólitos vegetais, diminuindo sua eficácia terapêutica e gerando substâncias tóxicas, além do risco de infecções por potenciais patógenos, sendo extremamente prejudiciais ao paciente. Contudo, nem todos os artigos seguiram corretamente o controle microbiológico preconizado pela legislação, o que mostra a necessidade de realizar o controle de qualidade microbiológico rigoroso e a adequação dos procedimentos à legislação vigente, a fim de garantir maior qualidade, segurança e eficácia do produto que é dispensado ao paciente. Tendo em vista o exposto, considera-se que os medicamentos fitoterápicos devem ser analisados com o mesmo rigor que os medicamentos sintéticos, no qual o controle microbiológico deve ocorrer em todas as etapas do processo de produção, a fim de minimizar os riscos de contaminação no produto final e, consequentemente, comercializar produtos próprios para o consumo humano.Research, Society and Development2022-08-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3300110.33448/rsd-v11i10.33001Research, Society and Development; Vol. 11 No. 10; e462111033001Research, Society and Development; Vol. 11 Núm. 10; e462111033001Research, Society and Development; v. 11 n. 10; e4621110330012525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/33001/27994Copyright (c) 2022 Juliana dos Santos Carmo; Joseli Maria da Rocha Nogueira; Líllian Oliveira Pereira da Silvahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCarmo, Juliana dos SantosNogueira, Joseli Maria da RochaSilva, Líllian Oliveira Pereira da2022-08-12T22:23:03Zoai:ojs.pkp.sfu.ca:article/33001Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:48:47.473195Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv The importance of microbiological quality control in phytotherapy products and medicinal plants
La importancia del control de calidad microbiológica en productos de fitoterapia y plantas medicinales
A importância do controle de qualidade microbiológico em produtos fitoterápicos e plantas medicinais
title The importance of microbiological quality control in phytotherapy products and medicinal plants
spellingShingle The importance of microbiological quality control in phytotherapy products and medicinal plants
Carmo, Juliana dos Santos
Controle de qualidade
Medicamento fitoterápico
Microbiologia
Plantas medicinais.
Quality control
Phytotherapeutic drugs
Microbiology
Medicinal plants.
Control de calidad
Medicamento fitoterápico
Microbiología
Plantas medicinales.
title_short The importance of microbiological quality control in phytotherapy products and medicinal plants
title_full The importance of microbiological quality control in phytotherapy products and medicinal plants
title_fullStr The importance of microbiological quality control in phytotherapy products and medicinal plants
title_full_unstemmed The importance of microbiological quality control in phytotherapy products and medicinal plants
title_sort The importance of microbiological quality control in phytotherapy products and medicinal plants
author Carmo, Juliana dos Santos
author_facet Carmo, Juliana dos Santos
Nogueira, Joseli Maria da Rocha
Silva, Líllian Oliveira Pereira da
author_role author
author2 Nogueira, Joseli Maria da Rocha
Silva, Líllian Oliveira Pereira da
author2_role author
author
dc.contributor.author.fl_str_mv Carmo, Juliana dos Santos
Nogueira, Joseli Maria da Rocha
Silva, Líllian Oliveira Pereira da
dc.subject.por.fl_str_mv Controle de qualidade
Medicamento fitoterápico
Microbiologia
Plantas medicinais.
Quality control
Phytotherapeutic drugs
Microbiology
Medicinal plants.
Control de calidad
Medicamento fitoterápico
Microbiología
Plantas medicinales.
topic Controle de qualidade
Medicamento fitoterápico
Microbiologia
Plantas medicinais.
Quality control
Phytotherapeutic drugs
Microbiology
Medicinal plants.
Control de calidad
Medicamento fitoterápico
Microbiología
Plantas medicinales.
description Phytotherapeutic drugs and medicinal plants have been used to treat diseases for thousands of years and the expansion of their use has increased the need for a more rigorous microbiological quality control, since microbial contamination can affect the quality of the product and the health of the individual. From this, the present study aimed to analyze different methodologies applied in the microbiological quality control of phytotherapics and medicinal plants, in order to highlight their importance. This is, therefore, a literature review, in which articles published between 2016 and 2022 were analyzed. More than half of the selected articles (55%) addressed Phytotherapeutic drugs or medicinal plants with high microbial contamination, which can cause changes chemical characteristics of plant metabolites, reducing their therapeutic efficacy and generating toxic substances, in addition to the risk of infections by potential pathogens, being extremely harmful to the patient. However, not all articles correctly followed the microbiological control recommended by the legislation, which shows the need to carry out rigorous microbiological quality control and the adequacy of procedures to current legislation, in order to guarantee greater quality, safety and effectiveness of the product that is delivered to the patient. In view of the above, it is considered that Phytotherapeutic drugs should be analyzed with the same rigor as synthetic medicines, in which microbiological control must occur at all stages of the production process, in order to minimize the risks of contamination in the product and, consequently, commercialize products suitable for human consumption.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-07
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33001
10.33448/rsd-v11i10.33001
url https://rsdjournal.org/index.php/rsd/article/view/33001
identifier_str_mv 10.33448/rsd-v11i10.33001
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33001/27994
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 10; e462111033001
Research, Society and Development; Vol. 11 Núm. 10; e462111033001
Research, Society and Development; v. 11 n. 10; e462111033001
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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