Impact of nutrigenomics in the Prevention of chronic diseases: a review
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/23681 |
Resumo: | Nutrigenomics studies have identified genetic variants that influence specific nutrient intake and metabolism and predict the variability of individuals in response to dietary interventions. Metabolomics revealed the metabolic impressions of food and nutrient consumption and discovered new metabolic pathways potentially modified by diet. This work aimed to investigate the scientific evidence that proves the effectiveness of nutrigenomics in food and the prevention of chronic non-communicable diseases, as well as the impact of nutrients in the modulation of gene expression and prevention of these pathologies. It is an integrative review that allows combining data from the theoretical literature that can guide the definition of concepts, identification, review and methodological analysis of studies on the subject. Evidence from gene-nutrient interaction studies with CNCDs is relevant not only for identifying the influence of a particular gene on a phenotype in a population with different dietary habits that can potentially affect this phenotype, but also for evaluating the response of a dietary intervention among individuals with different genotypes. The study related to nutrigenomics, more specifically with nutritional genomics, brings several relevant and very important aspects, possible benefits for improving the quality of life, making it possible to modulate gene expression in the human genome through bioactive compounds and nutrients in food. |
| id |
UNIFEI_0cfa99d09caf9930e9f1368cddad56b6 |
|---|---|
| oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/23681 |
| network_acronym_str |
UNIFEI |
| network_name_str |
Research, Society and Development |
| repository_id_str |
|
| spelling |
Impact of nutrigenomics in the Prevention of chronic diseases: a review Impacto de la nutrigenómica en la prevención de enfermedades crónicas: una revisiónImpacto da nutrigenômica na prevenção de doenças crônicas: uma revisãoNutrigenomicsNutrientsChronic diseases Prevention.NutrigenomicaNutrientesPrevención de enfermedades crónicas.NutrigenômicaNutrientesPrevenção de doenças crônicas.Nutrigenomics studies have identified genetic variants that influence specific nutrient intake and metabolism and predict the variability of individuals in response to dietary interventions. Metabolomics revealed the metabolic impressions of food and nutrient consumption and discovered new metabolic pathways potentially modified by diet. This work aimed to investigate the scientific evidence that proves the effectiveness of nutrigenomics in food and the prevention of chronic non-communicable diseases, as well as the impact of nutrients in the modulation of gene expression and prevention of these pathologies. It is an integrative review that allows combining data from the theoretical literature that can guide the definition of concepts, identification, review and methodological analysis of studies on the subject. Evidence from gene-nutrient interaction studies with CNCDs is relevant not only for identifying the influence of a particular gene on a phenotype in a population with different dietary habits that can potentially affect this phenotype, but also for evaluating the response of a dietary intervention among individuals with different genotypes. The study related to nutrigenomics, more specifically with nutritional genomics, brings several relevant and very important aspects, possible benefits for improving the quality of life, making it possible to modulate gene expression in the human genome through bioactive compounds and nutrients in food.Los estudios de nutrigenómica han identificado variantes genéticas que influyen en la ingesta y el metabolismo de nutrientes específicos y predicen la variabilidad de los individuos en respuesta a las intervenciones dietéticas. La metabolómica reveló las impresiones metabólicas del consumo de alimentos y nutrientes y descubrió nuevas vías metabólicas potencialmente modificadas por la dieta. Este trabajo tuvo como objetivo investigar la evidencia científica que acredite la efectividad de la nutrigenómica en los alimentos y la prevención de enfermedades crónicas no transmisibles, así como el impacto de los nutrientes en la modulación de la expresión génica y prevención de estas patologías. Es una revisión integradora que permite combinar datos de la literatura teórica que pueden orientar la definición de conceptos, identificación, revisión y análisis metodológico de estudios sobre el tema. La evidencia de los estudios de interacción entre genes y nutrientes con las ECNT es relevante no solo para identificar la influencia de un gen en particular en un fenotipo en una población con diferentes hábitos alimenticios que potencialmente pueden afectar este fenotipo, sino también para evaluar la respuesta de una intervención dietética entre individuos. con diferentes genotipos. El estudio relacionado con la nutrigenómica, más concretamente con la genómica nutricional, trae varios aspectos relevantes y muy importantes, posibles beneficios para mejorar la calidad de vida, permitiendo modular la expresión génica en el genoma humano a través de compuestos bioactivos y nutrientes en los alimentos.Os estudos da nutrigenômica identificaram variantes genéticas que influenciam a ingestão e metabolismo de nutrientes específicos e preveem a variabilidade dos indivíduos em resposta a intervenções dietéticas. A metabolômica, revelou as impressões metabólicas do consumo de alimentos e nutrientes e descobriu novas vias metabólicas potencialmente modificadas pela dieta. Este trabalho teve como objetivo investigar as evidências científicas que comprovam a eficácia da nutrigenômica na alimentação e a prevenção de doenças crônicas não transmissíveis, bem como o impacto dos nutrientes na modulação da expressão gênica e prevenção destas patologias. Trata-se de uma revisão integrativa que permite combinar dados da literatura teórica que poderão direcionar a definição de conceitos, identificação, revisão e análise metodológica dos estudos sobre o tema. As evidências dos estudos de interação entre gene e nutriente com as DCNT’s são relevantes não somente por identificarem a influência de um determinado gene, sobre um fenótipo em uma população com diferentes hábitos alimentares que podem potencialmente afetar esse fenótipo, mas também por avaliarem a resposta de uma intervenção dietética entre indivíduos com diferentes genótipos. O estudo relacionado a nutrigenômica mais especificamente com a genômica nutricional trás vários aspectos relevantes e de grande importância, possíveis benefícios para a melhora da qualidade de vida fazendo com que através dos compostos bioativos e nutrientes dos alimentos modulem a expressão gênica no genoma humano.Research, Society and Development2021-12-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2368110.33448/rsd-v10i16.23681Research, Society and Development; Vol. 10 No. 16; e245101623681Research, Society and Development; Vol. 10 Núm. 16; e245101623681Research, Society and Development; v. 10 n. 16; e2451016236812525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/23681/20903Copyright (c) 2021 Laíne de Almeida Sousa; Mikaelle Ravanna Oliveira Nascimento; Keila Cristiane Batista Bezerrahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSousa, Laíne de Almeida Nascimento, Mikaelle Ravanna Oliveira Bezerra, Keila Cristiane Batista 2021-12-20T11:03:07Zoai:ojs.pkp.sfu.ca:article/23681Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:42:28.551248Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Impact of nutrigenomics in the Prevention of chronic diseases: a review Impacto de la nutrigenómica en la prevención de enfermedades crónicas: una revisión Impacto da nutrigenômica na prevenção de doenças crônicas: uma revisão |
| title |
Impact of nutrigenomics in the Prevention of chronic diseases: a review |
| spellingShingle |
Impact of nutrigenomics in the Prevention of chronic diseases: a review Sousa, Laíne de Almeida Nutrigenomics Nutrients Chronic diseases Prevention. Nutrigenomica Nutrientes Prevención de enfermedades crónicas. Nutrigenômica Nutrientes Prevenção de doenças crônicas. |
| title_short |
Impact of nutrigenomics in the Prevention of chronic diseases: a review |
| title_full |
Impact of nutrigenomics in the Prevention of chronic diseases: a review |
| title_fullStr |
Impact of nutrigenomics in the Prevention of chronic diseases: a review |
| title_full_unstemmed |
Impact of nutrigenomics in the Prevention of chronic diseases: a review |
| title_sort |
Impact of nutrigenomics in the Prevention of chronic diseases: a review |
| author |
Sousa, Laíne de Almeida |
| author_facet |
Sousa, Laíne de Almeida Nascimento, Mikaelle Ravanna Oliveira Bezerra, Keila Cristiane Batista |
| author_role |
author |
| author2 |
Nascimento, Mikaelle Ravanna Oliveira Bezerra, Keila Cristiane Batista |
| author2_role |
author author |
| dc.contributor.author.fl_str_mv |
Sousa, Laíne de Almeida Nascimento, Mikaelle Ravanna Oliveira Bezerra, Keila Cristiane Batista |
| dc.subject.por.fl_str_mv |
Nutrigenomics Nutrients Chronic diseases Prevention. Nutrigenomica Nutrientes Prevención de enfermedades crónicas. Nutrigenômica Nutrientes Prevenção de doenças crônicas. |
| topic |
Nutrigenomics Nutrients Chronic diseases Prevention. Nutrigenomica Nutrientes Prevención de enfermedades crónicas. Nutrigenômica Nutrientes Prevenção de doenças crônicas. |
| description |
Nutrigenomics studies have identified genetic variants that influence specific nutrient intake and metabolism and predict the variability of individuals in response to dietary interventions. Metabolomics revealed the metabolic impressions of food and nutrient consumption and discovered new metabolic pathways potentially modified by diet. This work aimed to investigate the scientific evidence that proves the effectiveness of nutrigenomics in food and the prevention of chronic non-communicable diseases, as well as the impact of nutrients in the modulation of gene expression and prevention of these pathologies. It is an integrative review that allows combining data from the theoretical literature that can guide the definition of concepts, identification, review and methodological analysis of studies on the subject. Evidence from gene-nutrient interaction studies with CNCDs is relevant not only for identifying the influence of a particular gene on a phenotype in a population with different dietary habits that can potentially affect this phenotype, but also for evaluating the response of a dietary intervention among individuals with different genotypes. The study related to nutrigenomics, more specifically with nutritional genomics, brings several relevant and very important aspects, possible benefits for improving the quality of life, making it possible to modulate gene expression in the human genome through bioactive compounds and nutrients in food. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-12-12 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/23681 10.33448/rsd-v10i16.23681 |
| url |
https://rsdjournal.org/index.php/rsd/article/view/23681 |
| identifier_str_mv |
10.33448/rsd-v10i16.23681 |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/23681/20903 |
| dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
application/pdf |
| dc.publisher.none.fl_str_mv |
Research, Society and Development |
| publisher.none.fl_str_mv |
Research, Society and Development |
| dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 16; e245101623681 Research, Society and Development; Vol. 10 Núm. 16; e245101623681 Research, Society and Development; v. 10 n. 16; e245101623681 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
| instname_str |
Universidade Federal de Itajubá (UNIFEI) |
| instacron_str |
UNIFEI |
| institution |
UNIFEI |
| reponame_str |
Research, Society and Development |
| collection |
Research, Society and Development |
| repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
| repository.mail.fl_str_mv |
rsd.articles@gmail.com |
| _version_ |
1797052759543906304 |