Complications in hospitalized COVID-19 patients with decompensated heart failure

Detalhes bibliográficos
Autor(a) principal: Santos, Gabriela Silva
Data de Publicação: 2022
Outros Autores: Santos, Gabriel Barbosa Figueira dos, Bispo, Laura Dayane Gois, Santos, Debora Santana, Tavares, Gilberto Andrade, Meneguz-Moreno, Rafael Alexandre, Campos, Viviane Correia
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/32860
Resumo: Objective: To analyze the development of complications during hospitalization of patients with COVID-19 and HF. Method: This is an observational, quantitative study, based on the review of medical records of patients admitted to the Respiratory Diseases Unit (RDU) of a University Hospital in northeastern Brazil, with RT-PCR reagent for SARS-COV2 and diagnosis of HF. Results: Of the 77 patients, 51 (66.2%) had an acute chronic heart failure (CHF) while the others (n = 26; 33.8%) had no history of previous heart disease and were having their first episode of heart failure. acute (ICA). Those with the NYHA IV classification had a higher risk of developing shock (p = 0.001), cardiopulmonary arrest (CPA) (p = 0.01), acute respiratory distress syndrome (ARDS) (p < 0.0001), bacteremia (p = 0.008), hemorrhage and liver damage (p = 0.04) as complications. The in-hospital mortality rate was 39% (n=30). When analyzing the relationship between the type of complication developed and the outcome death, shock, CPA, ARDS (p < 0.0001), pneumonia (p = 0.009), bacteremia (p = 0.0003), hemorrhage, anemia (p = 0.02), cardiac arrhythmia (p = 0.03) and liver damage (p = 0.04) were significantly associated. Conclusion: The association between HF and COVID-19 on admission leads to a high in-hospital mortality rate. Patients with NYHA functional class IV have a higher risk of developing complications and death during hospitalization. In addition, patients with HF and COVID-19 who develop pneumonia, ARDS, shock, CA, anemia, hemorrhage, arrhythmia, liver damage, and/or bacteremia have a higher mortality rate.
id UNIFEI_1500a208e16be2585b5b622668d6cd48
oai_identifier_str oai:ojs.pkp.sfu.ca:article/32860
network_acronym_str UNIFEI
network_name_str Research, Society and Development
repository_id_str
spelling Complications in hospitalized COVID-19 patients with decompensated heart failureComplicaciones en pacientes hospitalizados por COVID-19 con insuficiencia cardiaca descompensadaComplicações em pacientes internados por COVID-19 com insuficiência cardíaca descompensadaInsuficiência cardíacaCOVID-19hospitalização. Insuficiencia cardíacaCOVID-19Hospitalización.Heart failureCOVID-19Hospitalization.Objective: To analyze the development of complications during hospitalization of patients with COVID-19 and HF. Method: This is an observational, quantitative study, based on the review of medical records of patients admitted to the Respiratory Diseases Unit (RDU) of a University Hospital in northeastern Brazil, with RT-PCR reagent for SARS-COV2 and diagnosis of HF. Results: Of the 77 patients, 51 (66.2%) had an acute chronic heart failure (CHF) while the others (n = 26; 33.8%) had no history of previous heart disease and were having their first episode of heart failure. acute (ICA). Those with the NYHA IV classification had a higher risk of developing shock (p = 0.001), cardiopulmonary arrest (CPA) (p = 0.01), acute respiratory distress syndrome (ARDS) (p < 0.0001), bacteremia (p = 0.008), hemorrhage and liver damage (p = 0.04) as complications. The in-hospital mortality rate was 39% (n=30). When analyzing the relationship between the type of complication developed and the outcome death, shock, CPA, ARDS (p < 0.0001), pneumonia (p = 0.009), bacteremia (p = 0.0003), hemorrhage, anemia (p = 0.02), cardiac arrhythmia (p = 0.03) and liver damage (p = 0.04) were significantly associated. Conclusion: The association between HF and COVID-19 on admission leads to a high in-hospital mortality rate. Patients with NYHA functional class IV have a higher risk of developing complications and death during hospitalization. In addition, patients with HF and COVID-19 who develop pneumonia, ARDS, shock, CA, anemia, hemorrhage, arrhythmia, liver damage, and/or bacteremia have a higher mortality rate.Objetivo: Analizar el desarrollo de complicaciones durante la hospitalización de pacientes con COVID-19 e IC. Método: Se trata de un estudio observacional, cuantitativo, basado en la revisión de histórias clínicas de pacientes ingresados en la Unidad de Enfermedades Respiratorias (URD) de un Hospital Universitario del nordeste de Brasil, con reactivo RT-PCR para SARS-COV2 y diagnóstico de IC. Resultados: De los 77 pacientes, 51 (66,2%) tenían insuficiencia cardíaca crónica aguda (ICC) mientras que los demás (n = 26; 33,8%) no tenían antecedentes de enfermedad cardíaca previa y estaban teniendo su primer episódio de insuficiencia cardíaca aguda. (ICA). Aquellos con la clasificación NYHA IV tenían mayor riesgo de desarrollar shock (p = 0,001), paro cardíaco (CPA) (p = 0,01), síndrome de dificultad respiratoria aguda (SDRA) (p < 0,0001), bacteriemia (p = 0,008), hemorragia y daño hepático (p = 0,04) como complicaciones. La tasa de mortalidad hospitalaria fue del 39% (n=30). Al analizar la relación entre el tipo de complicación desarrollada y el desenlace muerte, shock, PCA, SDRA (p < 0,0001), neumonía (p = 0,009), bacteriemia (p = 0,0003), hemorragia, anemia (p = 0,02), cardiopatía la arritmia (p = 0,03) y el daño hepático (p = 0,04) se asociaron significativamente. Conclusión: La asociación entre IC y COVID-19 al ingreso conduce a una alta tasa de mortalidad hospitalaria. Los pacientes con clase funcional IV de la NYHA tienen mayor riesgo de desarrollar complicaciones y muerte durante la hospitalización. Además, los pacientes con IC y COVID-19 que desarrollan neumonía, SDRA, shock, AC, anemia, hemorragia, arritmia, daño hepático y/o bacteriemia tienen una mayor tasa de mortalidad.Objetivo: Analisar o desenvolvimento de complicações durante a internação de pacientes com COVID-19 e IC. Método: Trata-se de um estudo observacional, quantitativo, a partir da revisão dos prontuários dos pacientes internados na Unidade de Doenças Respiratórias (UDR) de um Hospital Universitário do nordeste brasileiro, com RT-PCR reagente para SARS-COV2 e diagnóstico de IC. Resultados: Dos 77 pacientes, 51 (66,2%) apresentavam uma insuficiência cardíaca crônica agudizada (ICCa) enquanto os demais (n = 26; 33,8%) não tinham história de cardiopatia prévia e estavam apresentando o primeiro episódio de insuficiência cardíaca aguda (ICA). Aqueles com a classificação NYHA IV tiveram maior risco de desenvolver choque (p = 0,001), parada cardiorrespiratória (PCR) (p = 0,01), síndrome do desconforto respiratório agudo (SDRA) (p < 0,0001), bacteremia (p = 0,008), hemorragia e dano hepático (p = 0,04) como complicações. A taxa de mortalidade intra-hospitalar foi de 39% (n= 30).  Ao analisar a relação entre o tipo de complicação desenvolvida com o desfecho óbito, choque, PCR, SDRA (p < 0,0001), pneumonia (p = 0,009), bacteremia (p = 0,0003), hemorragia, anemia (p = 0,02), arritmia cardíaca (p = 0,03) e dano hepático (p = 0,04) tiveram associação significante. Conclusão: A associação entre IC e COVID-19 na internação leva a uma alta taxa de mortalidade intra-hospitalar. Pacientes com a classe funcional NYHA IV possuem maior risco de desenvolver complicações e óbito durante internação.  Além disso, os pacientes com IC e COVID-19 que desenvolvem pneumonia, SDRA, choque, PCR, anemia, hemorragia, arritmia, dano hepático e/ou bacteremia possuem maior taxa de mortalidade.Research, Society and Development2022-08-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3286010.33448/rsd-v11i10.32860Research, Society and Development; Vol. 11 No. 10; e419111032860Research, Society and Development; Vol. 11 Núm. 10; e419111032860Research, Society and Development; v. 11 n. 10; e4191110328602525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/32860/27929Copyright (c) 2022 Gabriela Silva Santos; Gabriel Barbosa Figueira dos Santos; Laura Dayane Gois Bispo; Debora Santana Santos; Gilberto Andrade Tavares; Rafael Alexandre Meneguz-Moreno; Viviane Correia Camposhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantos, Gabriela Silva Santos, Gabriel Barbosa Figueira dos Bispo, Laura Dayane GoisSantos, Debora Santana Tavares, Gilberto AndradeMeneguz-Moreno, Rafael AlexandreCampos, Viviane Correia2022-08-12T22:23:03Zoai:ojs.pkp.sfu.ca:article/32860Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:48:42.528015Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Complications in hospitalized COVID-19 patients with decompensated heart failure
Complicaciones en pacientes hospitalizados por COVID-19 con insuficiencia cardiaca descompensada
Complicações em pacientes internados por COVID-19 com insuficiência cardíaca descompensada
title Complications in hospitalized COVID-19 patients with decompensated heart failure
spellingShingle Complications in hospitalized COVID-19 patients with decompensated heart failure
Santos, Gabriela Silva
Insuficiência cardíaca
COVID-19
hospitalização.
Insuficiencia cardíaca
COVID-19
Hospitalización.
Heart failure
COVID-19
Hospitalization.
title_short Complications in hospitalized COVID-19 patients with decompensated heart failure
title_full Complications in hospitalized COVID-19 patients with decompensated heart failure
title_fullStr Complications in hospitalized COVID-19 patients with decompensated heart failure
title_full_unstemmed Complications in hospitalized COVID-19 patients with decompensated heart failure
title_sort Complications in hospitalized COVID-19 patients with decompensated heart failure
author Santos, Gabriela Silva
author_facet Santos, Gabriela Silva
Santos, Gabriel Barbosa Figueira dos
Bispo, Laura Dayane Gois
Santos, Debora Santana
Tavares, Gilberto Andrade
Meneguz-Moreno, Rafael Alexandre
Campos, Viviane Correia
author_role author
author2 Santos, Gabriel Barbosa Figueira dos
Bispo, Laura Dayane Gois
Santos, Debora Santana
Tavares, Gilberto Andrade
Meneguz-Moreno, Rafael Alexandre
Campos, Viviane Correia
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Santos, Gabriela Silva
Santos, Gabriel Barbosa Figueira dos
Bispo, Laura Dayane Gois
Santos, Debora Santana
Tavares, Gilberto Andrade
Meneguz-Moreno, Rafael Alexandre
Campos, Viviane Correia
dc.subject.por.fl_str_mv Insuficiência cardíaca
COVID-19
hospitalização.
Insuficiencia cardíaca
COVID-19
Hospitalización.
Heart failure
COVID-19
Hospitalization.
topic Insuficiência cardíaca
COVID-19
hospitalização.
Insuficiencia cardíaca
COVID-19
Hospitalización.
Heart failure
COVID-19
Hospitalization.
description Objective: To analyze the development of complications during hospitalization of patients with COVID-19 and HF. Method: This is an observational, quantitative study, based on the review of medical records of patients admitted to the Respiratory Diseases Unit (RDU) of a University Hospital in northeastern Brazil, with RT-PCR reagent for SARS-COV2 and diagnosis of HF. Results: Of the 77 patients, 51 (66.2%) had an acute chronic heart failure (CHF) while the others (n = 26; 33.8%) had no history of previous heart disease and were having their first episode of heart failure. acute (ICA). Those with the NYHA IV classification had a higher risk of developing shock (p = 0.001), cardiopulmonary arrest (CPA) (p = 0.01), acute respiratory distress syndrome (ARDS) (p < 0.0001), bacteremia (p = 0.008), hemorrhage and liver damage (p = 0.04) as complications. The in-hospital mortality rate was 39% (n=30). When analyzing the relationship between the type of complication developed and the outcome death, shock, CPA, ARDS (p < 0.0001), pneumonia (p = 0.009), bacteremia (p = 0.0003), hemorrhage, anemia (p = 0.02), cardiac arrhythmia (p = 0.03) and liver damage (p = 0.04) were significantly associated. Conclusion: The association between HF and COVID-19 on admission leads to a high in-hospital mortality rate. Patients with NYHA functional class IV have a higher risk of developing complications and death during hospitalization. In addition, patients with HF and COVID-19 who develop pneumonia, ARDS, shock, CA, anemia, hemorrhage, arrhythmia, liver damage, and/or bacteremia have a higher mortality rate.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-06
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/32860
10.33448/rsd-v11i10.32860
url https://rsdjournal.org/index.php/rsd/article/view/32860
identifier_str_mv 10.33448/rsd-v11i10.32860
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/32860/27929
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 10; e419111032860
Research, Society and Development; Vol. 11 Núm. 10; e419111032860
Research, Society and Development; v. 11 n. 10; e419111032860
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052796973875200