Chemical assessment, antioxidant and antimicrobial of leafs extracts of Virola sebifera, an Amazonian medicinal plant

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Claudiane Lima
Data de Publicação: 2021
Outros Autores: Silva, Rayele Moraes, Fernandes, Rachel de Moura Nunes, Araújo, Mirelle Ribeiro, Soares, Ilsamar Mendes, Silva, Juliana Fonseca Moreira da, Nascimento, Guilherme Nobre Lima do, Pimenta, Raphael Sanzio, Scapin, Elisandra
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/23068
Resumo: The high biodiversity of Amazon forest implies in a great number of plants with ethnopharmacological utilization. V. sebifera is one of the most important species of Virola genus, used in treatment of rheumatism, arthritis, dyspepsia, malaria, muscle pain and erysipelas. This study aimed to investigate its chemical composition, antioxidant and antimicrobial properties. For this, leafs extracts i) 70% ethanol in ultrasound bath (CEU); ii) 70% ethanol in Soxhlet (CES); and iii) sequential extraction in Soxhlet apparatus, starting with hexane (HE), followed by methanol (ME), and 70% ethanol extract (EE). Phenolic concentration, total flavonoid and antioxidant activity were assessed. The highest phenolic and total flavonoid contents were found in CEU and EE showed the best antioxidant activity. The most relevant substances identified by GC-MS analysis were the Kusunokinin, Hinokinin and catechol, among others first time related in V. sebifera. The antimicrobial activity was tested against Staphylococcus aureus, S. epidermidis, Salmonella typhimurium, Escherichia coli, and Candida albicans. The CEU, CES, EM, and EE obtained positive results against S. aureus and S. epidermidis. CES and EM also inhibited S. typhimurium and E. coli. Based on these results, V. sebifera can be recognized as a promising source of antioxidant and antimicrobial compounds.
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spelling Chemical assessment, antioxidant and antimicrobial of leafs extracts of Virola sebifera, an Amazonian medicinal plantEvaluación química, antioxidante y antimicrobiana de extractos de hojas de Virola sebifera, planta medicinal amazónica Avaliação química, antioxidante e antimicrobiana de extratos de folhas de Virola sebifera, uma planta medicinal amazônicaVirola sebiferaAmazônia LegalUcuubaComposição químicaAgentes antibacterianos.Virola sebiferaLegal AmazonUcuubaChemical compositionAnti-bacterial agents.Virola sebiferaAmazonia LegalUcuubaComposición químicaAgentes antibacterianos.The high biodiversity of Amazon forest implies in a great number of plants with ethnopharmacological utilization. V. sebifera is one of the most important species of Virola genus, used in treatment of rheumatism, arthritis, dyspepsia, malaria, muscle pain and erysipelas. This study aimed to investigate its chemical composition, antioxidant and antimicrobial properties. For this, leafs extracts i) 70% ethanol in ultrasound bath (CEU); ii) 70% ethanol in Soxhlet (CES); and iii) sequential extraction in Soxhlet apparatus, starting with hexane (HE), followed by methanol (ME), and 70% ethanol extract (EE). Phenolic concentration, total flavonoid and antioxidant activity were assessed. The highest phenolic and total flavonoid contents were found in CEU and EE showed the best antioxidant activity. The most relevant substances identified by GC-MS analysis were the Kusunokinin, Hinokinin and catechol, among others first time related in V. sebifera. The antimicrobial activity was tested against Staphylococcus aureus, S. epidermidis, Salmonella typhimurium, Escherichia coli, and Candida albicans. The CEU, CES, EM, and EE obtained positive results against S. aureus and S. epidermidis. CES and EM also inhibited S. typhimurium and E. coli. Based on these results, V. sebifera can be recognized as a promising source of antioxidant and antimicrobial compounds.La alta biodiversidad de la selva amazónica implica una gran cantidad de plantas con uso etnofarmacológico. V. sebifera es una de las especies más importantes del género Virola, utilizada en el tratamiento del reumatismo, artritis, dispepsia, malaria, dolores musculares y erisipela. Este estudio tuvo como objetivo investigar su composición química, propiedades antioxidantes y antimicrobianas. Para ello, extraiga las hojas i) etanol al 70% en un baño de ultrasonidos (CEU); ii) etanol al 70% en Soxhlet (CES); y iii) extracción secuencial en un aparato Soxhlet, comenzando con hexano (HE), seguido de metanol (ME) y extracto de etanol al 70% (EE). Se evaluó la concentración fenólica, flavonoide total y actividad antioxidante. Los niveles más altos de fenoles y flavonoides totales se encontraron en la CEU y la EE mostró la mejor actividad antioxidante. Las sustancias más relevantes identificadas por el análisis GC-MS fueron Kusunokinin, Hinokinin y catechol, entre otras enumeradas por primera vez en V. sebifera. La actividad antimicrobiana se probó contra Staphylococcus aureus, S. epidermidis, Salmonella typhimurium, Escherichia coli y Candida albicans. CEU, CES, EM y EE obtuvieron resultados positivos frente a S. aureus y S. epidermidis. CES y EM también inhibieron S. typhimurium y E. coli. Con base en estos resultados, V. sebifera puede reconocerse como una fuente prometedora de compuestos antioxidantes y antimicrobianos.A alta biodiversidade da floresta amazônica implica em um grande número de plantas com utilização etnofarmacológica. V. sebifera é uma das espécies mais importantes do gênero Virola, utilizada no tratamento de reumatismo, artrite, dispepsia, malária, dores musculares e erisipela. Este estudo teve como objetivo investigar sua composição química, propriedades antioxidantes e antimicrobianas. Para isso, extrai as folhas i) etanol 70% em banho de ultrassom (CEU); ii) etanol a 70% em Soxhlet (CES); e iii) extração sequencial em aparelho Soxhlet, começando com hexano (HE), seguido de metanol (ME) e extrato de etanol 70% (EE). Foram avaliadas a concentração fenólica, flavonóide total e atividade antioxidante. Os maiores teores de fenólicos e flavonóides totais foram encontrados no CEU e o EE apresentou a melhor atividade antioxidante. As substâncias mais relevantes identificadas pela análise GC-MS foram Kusunokinin, Hinokinin e catecol, entre outras relacionadas pela primeira vez em V. sebifera. A atividade antimicrobiana foi testada contra Staphylococcus aureus, S. epidermidis, Salmonella typhimurium, Escherichia coli e Candida albicans. O CEU, CES, EM e EE obtiveram resultados positivos contra S. aureus e S. epidermidis. CES e EM também inibiram S. typhimurium e E. coli. Com base nesses resultados, V. sebifera pode ser reconhecida como uma fonte promissora de compostos antioxidantes e antimicrobianos.Research, Society and Development2021-12-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2306810.33448/rsd-v10i15.23068Research, Society and Development; Vol. 10 No. 15; e578101523068Research, Society and Development; Vol. 10 Núm. 15; e578101523068Research, Society and Development; v. 10 n. 15; e5781015230682525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/23068/20594Copyright (c) 2021 Claudiane Lima Ribeiro; Rayele Moraes Silva; Rachel de Moura Nunes Fernandes; Mirelle Ribeiro Araújo; Ilsamar Mendes Soares; Juliana Fonseca Moreira da Silva; Guilherme Nobre Lima do Nascimento; Raphael Sanzio Pimenta; Elisandra Scapinhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessRibeiro, Claudiane Lima Silva, Rayele Moraes Fernandes, Rachel de Moura Nunes Araújo, Mirelle RibeiroSoares, Ilsamar Mendes Silva, Juliana Fonseca Moreira da Nascimento, Guilherme Nobre Lima do Pimenta, Raphael Sanzio Scapin, Elisandra2021-12-06T10:13:53Zoai:ojs.pkp.sfu.ca:article/23068Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:42:03.186104Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Chemical assessment, antioxidant and antimicrobial of leafs extracts of Virola sebifera, an Amazonian medicinal plant
Evaluación química, antioxidante y antimicrobiana de extractos de hojas de Virola sebifera, planta medicinal amazónica
Avaliação química, antioxidante e antimicrobiana de extratos de folhas de Virola sebifera, uma planta medicinal amazônica
title Chemical assessment, antioxidant and antimicrobial of leafs extracts of Virola sebifera, an Amazonian medicinal plant
spellingShingle Chemical assessment, antioxidant and antimicrobial of leafs extracts of Virola sebifera, an Amazonian medicinal plant
Ribeiro, Claudiane Lima
Virola sebifera
Amazônia Legal
Ucuuba
Composição química
Agentes antibacterianos.
Virola sebifera
Legal Amazon
Ucuuba
Chemical composition
Anti-bacterial agents.
Virola sebifera
Amazonia Legal
Ucuuba
Composición química
Agentes antibacterianos.
title_short Chemical assessment, antioxidant and antimicrobial of leafs extracts of Virola sebifera, an Amazonian medicinal plant
title_full Chemical assessment, antioxidant and antimicrobial of leafs extracts of Virola sebifera, an Amazonian medicinal plant
title_fullStr Chemical assessment, antioxidant and antimicrobial of leafs extracts of Virola sebifera, an Amazonian medicinal plant
title_full_unstemmed Chemical assessment, antioxidant and antimicrobial of leafs extracts of Virola sebifera, an Amazonian medicinal plant
title_sort Chemical assessment, antioxidant and antimicrobial of leafs extracts of Virola sebifera, an Amazonian medicinal plant
author Ribeiro, Claudiane Lima
author_facet Ribeiro, Claudiane Lima
Silva, Rayele Moraes
Fernandes, Rachel de Moura Nunes
Araújo, Mirelle Ribeiro
Soares, Ilsamar Mendes
Silva, Juliana Fonseca Moreira da
Nascimento, Guilherme Nobre Lima do
Pimenta, Raphael Sanzio
Scapin, Elisandra
author_role author
author2 Silva, Rayele Moraes
Fernandes, Rachel de Moura Nunes
Araújo, Mirelle Ribeiro
Soares, Ilsamar Mendes
Silva, Juliana Fonseca Moreira da
Nascimento, Guilherme Nobre Lima do
Pimenta, Raphael Sanzio
Scapin, Elisandra
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Ribeiro, Claudiane Lima
Silva, Rayele Moraes
Fernandes, Rachel de Moura Nunes
Araújo, Mirelle Ribeiro
Soares, Ilsamar Mendes
Silva, Juliana Fonseca Moreira da
Nascimento, Guilherme Nobre Lima do
Pimenta, Raphael Sanzio
Scapin, Elisandra
dc.subject.por.fl_str_mv Virola sebifera
Amazônia Legal
Ucuuba
Composição química
Agentes antibacterianos.
Virola sebifera
Legal Amazon
Ucuuba
Chemical composition
Anti-bacterial agents.
Virola sebifera
Amazonia Legal
Ucuuba
Composición química
Agentes antibacterianos.
topic Virola sebifera
Amazônia Legal
Ucuuba
Composição química
Agentes antibacterianos.
Virola sebifera
Legal Amazon
Ucuuba
Chemical composition
Anti-bacterial agents.
Virola sebifera
Amazonia Legal
Ucuuba
Composición química
Agentes antibacterianos.
description The high biodiversity of Amazon forest implies in a great number of plants with ethnopharmacological utilization. V. sebifera is one of the most important species of Virola genus, used in treatment of rheumatism, arthritis, dyspepsia, malaria, muscle pain and erysipelas. This study aimed to investigate its chemical composition, antioxidant and antimicrobial properties. For this, leafs extracts i) 70% ethanol in ultrasound bath (CEU); ii) 70% ethanol in Soxhlet (CES); and iii) sequential extraction in Soxhlet apparatus, starting with hexane (HE), followed by methanol (ME), and 70% ethanol extract (EE). Phenolic concentration, total flavonoid and antioxidant activity were assessed. The highest phenolic and total flavonoid contents were found in CEU and EE showed the best antioxidant activity. The most relevant substances identified by GC-MS analysis were the Kusunokinin, Hinokinin and catechol, among others first time related in V. sebifera. The antimicrobial activity was tested against Staphylococcus aureus, S. epidermidis, Salmonella typhimurium, Escherichia coli, and Candida albicans. The CEU, CES, EM, and EE obtained positive results against S. aureus and S. epidermidis. CES and EM also inhibited S. typhimurium and E. coli. Based on these results, V. sebifera can be recognized as a promising source of antioxidant and antimicrobial compounds.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/23068
10.33448/rsd-v10i15.23068
url https://rsdjournal.org/index.php/rsd/article/view/23068
identifier_str_mv 10.33448/rsd-v10i15.23068
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/23068/20594
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 15; e578101523068
Research, Society and Development; Vol. 10 Núm. 15; e578101523068
Research, Society and Development; v. 10 n. 15; e578101523068
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052696618860544

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