Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing

Detalhes bibliográficos
Autor(a) principal: Paiva, Moises Marques
Data de Publicação: 2021
Outros Autores: Costa Filho, Evilasio Anisio, Santos, Bruna Giovanna Barbosa dos, Santos, Kleilton Oliveira, Sousa, Wladymyr Jefferson Bacalhau de, Assis Júnior, Pedro Carlos de, Cardoso, Márcio José Batista
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/21348
Resumo: Polyvinylpyrrolidone and chitosan biopolymers are biomaterials used in wound treatment, due to their biological, physicochemical, and other properties, in addition to their processability. Controlling the viscosity of polymers is of fundamental importance for processing and consequently for the properties of membranes, such as adhesiveness, crucial for medical applications in wounds. In this sense, the research proposal was to simulate and evaluate the viscosity of polymeric mixtures of medium molar mass (QM) chitosan and polyvinylpyrrolidone (PVP) in different concentrations and proportions for the synthesis of adhesive membranes. To this end, the viscosity of pure polymers was evaluated in the literature, a linear model for the viscosity of the mixtures was simulated and, subsequently, the response surface methodology (MSR) was applied using the central composite model, for three QM/PVP ratios at different concentrations of the solutions. The viscosity of QM and PVP polymers present an exponential growth trend line, based on literature data, having a satisfactory regression coefficient, and the linear simulation model for viscosity of the mixtures, proved to be satisfactory, considering a variation of 5%. The surface response and contour graphs make evident the effect of solution concentration and polymer mix ratio, and in which mixing situations it is possible to achieve higher and lower viscosity levels. The information obtained in the research is extremely useful, aiding in the development of polymeric mixtures, in order to seek the best conditions, reduce the time of experiments focusing on points of interest.
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spelling Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processingModelado de viscosidad en mezcla de polivinilpirrolidona/quitosano para procesamiento de membranas adhesivasModelagem da viscosidade em mistura polivinilpirrolidona/quitosana para processamento de membrana adesivaQuitosanoPolivinilpirrolidonaViscosidadMejoramientoMezclas.ChitosanPolyvinylpyrrolidoneViscosityOptimizationMixtures.QuitosanaPolivinilpirrolidonaViscosidadeOtimizaçãoMisturas.Polyvinylpyrrolidone and chitosan biopolymers are biomaterials used in wound treatment, due to their biological, physicochemical, and other properties, in addition to their processability. Controlling the viscosity of polymers is of fundamental importance for processing and consequently for the properties of membranes, such as adhesiveness, crucial for medical applications in wounds. In this sense, the research proposal was to simulate and evaluate the viscosity of polymeric mixtures of medium molar mass (QM) chitosan and polyvinylpyrrolidone (PVP) in different concentrations and proportions for the synthesis of adhesive membranes. To this end, the viscosity of pure polymers was evaluated in the literature, a linear model for the viscosity of the mixtures was simulated and, subsequently, the response surface methodology (MSR) was applied using the central composite model, for three QM/PVP ratios at different concentrations of the solutions. The viscosity of QM and PVP polymers present an exponential growth trend line, based on literature data, having a satisfactory regression coefficient, and the linear simulation model for viscosity of the mixtures, proved to be satisfactory, considering a variation of 5%. The surface response and contour graphs make evident the effect of solution concentration and polymer mix ratio, and in which mixing situations it is possible to achieve higher and lower viscosity levels. The information obtained in the research is extremely useful, aiding in the development of polymeric mixtures, in order to seek the best conditions, reduce the time of experiments focusing on points of interest.Los biopolímeros de polivinilpirrolidona y quitosano son biomateriales utilizados en el tratamiento de heridas, debido a sus propiedades biológicas, fisicoquímicas y otras, además de su procesabilidad. El control de la viscosidad de los polímeros es de fundamental importancia para el procesamiento y, en consecuencia, para las propiedades de las membranas, como la adhesividad, crucial para aplicaciones médicas en heridas. En este sentido, la propuesta de investigación fue simular y evaluar la viscosidad de mezclas poliméricas de quitosano de masa molar media (QM) y polivinilpirrolidona (PVP) en diferentes concentraciones y proporciones para la síntesis de membranas adhesivas. Para ello, se evaluó en la literatura la viscosidad de polímeros puros, se simuló un modelo lineal para la viscosidad de las mezclas y, posteriormente, se aplicó la metodología de superficie de respuesta (MSR) utilizando el modelo compuesto central, para tres QM / PVP proporciones a diferentes concentraciones de las soluciones. La viscosidad de los polímeros QM y PVP presenta una línea de tendencia de crecimiento exponencial, con base en los datos de la literatura, teniendo un coeficiente de regresión satisfactorio, y el modelo de simulación lineal para la viscosidad de las mezclas, resultó satisfactorio, considerando una variación del 5%. La respuesta de la superficie y los gráficos de contorno hacen evidente el efecto de la concentración de la solución y la relación de mezcla del polímero, y en qué situaciones de mezcla es posible lograr niveles de viscosidad más altos y más bajos. La información obtenida en la investigación es sumamente útil, ayudando en el desarrollo de mezclas poliméricas, con el fin de buscar las mejores condiciones, reducir el tiempo de experimentos enfocados en puntos de interés.Os biopolímeros polivinilpirrolidona e quitosana são biomateriais utilizados no tratamento de feridas, devido suas propriedades biológicas, físico-química entre outras, além de sua processabilidade. O controle da viscosidade dos polímeros é de fundamental importância para o processamento e consequentemente das propriedades das membranas, como a adesividade, crucial para aplicações de médicas em feridas.  Nesse sentido, a proposta da pesquisa foi simular e avaliar a viscosidade de misturas poliméricas de quitosana de média massa molar (QM) e polivinilpirrolidona (PVP) em diferentes concentrações e proporções para síntese de membranas adesivas. Para tal, foi avaliado na literatura a viscosidade dos polímeros puros, simulado um modelo linear para viscosidade das misturas e, posteriormente, aplicado a metodologia de superfície de resposta (MSR) utilizando o modelo composto central, para três proporções QM/PVP em diferentes concentrações das soluções.  A viscosidade dos polímeros QM e o PVP apresentam uma linha de tendência de crescimento exponencial, com baseado em dados da literatura, tendo um coeficiente de regressão satisfatório, e o modelo linear de simulação para viscosidade das misturas, demonstrou ser satisfatórios, considerando uma variação de 5%. Os gráficos de superfície resposta e contorno deixam evidentes o efeito da concentração da solução e proporção de mistura polimérica, e em quais situações de mistura é possível atingir níveis mais elevados e reduzidos da viscosidade. As informações obtidas na pesquisa são extremamente úteis, auxiliando no desenvolvimento das misturas poliméricas, de forma, a buscar as melhores condições, reduzir tempo de experimentos focando pontos de interesse.Research, Society and Development2021-10-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2134810.33448/rsd-v10i13.21348Research, Society and Development; Vol. 10 No. 13; e373101321348Research, Society and Development; Vol. 10 Núm. 13; e373101321348Research, Society and Development; v. 10 n. 13; e3731013213482525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/21348/19273Copyright (c) 2021 Moises Marques Paiva; Evilasio Anisio Costa Filho; Bruna Giovanna Barbosa dos Santos; Kleilton Oliveira Santos; Wladymyr Jefferson Bacalhau de Sousa; Pedro Carlos de Assis Júnior; Márcio José Batista Cardosohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPaiva, Moises Marques Costa Filho, Evilasio Anisio Santos, Bruna Giovanna Barbosa dos Santos, Kleilton Oliveira Sousa, Wladymyr Jefferson Bacalhau de Assis Júnior, Pedro Carlos de Cardoso, Márcio José Batista 2021-11-21T18:26:28Zoai:ojs.pkp.sfu.ca:article/21348Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:40:46.935191Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing
Modelado de viscosidad en mezcla de polivinilpirrolidona/quitosano para procesamiento de membranas adhesivas
Modelagem da viscosidade em mistura polivinilpirrolidona/quitosana para processamento de membrana adesiva
title Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing
spellingShingle Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing
Paiva, Moises Marques
Quitosano
Polivinilpirrolidona
Viscosidad
Mejoramiento
Mezclas.
Chitosan
Polyvinylpyrrolidone
Viscosity
Optimization
Mixtures.
Quitosana
Polivinilpirrolidona
Viscosidade
Otimização
Misturas.
title_short Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing
title_full Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing
title_fullStr Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing
title_full_unstemmed Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing
title_sort Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing
author Paiva, Moises Marques
author_facet Paiva, Moises Marques
Costa Filho, Evilasio Anisio
Santos, Bruna Giovanna Barbosa dos
Santos, Kleilton Oliveira
Sousa, Wladymyr Jefferson Bacalhau de
Assis Júnior, Pedro Carlos de
Cardoso, Márcio José Batista
author_role author
author2 Costa Filho, Evilasio Anisio
Santos, Bruna Giovanna Barbosa dos
Santos, Kleilton Oliveira
Sousa, Wladymyr Jefferson Bacalhau de
Assis Júnior, Pedro Carlos de
Cardoso, Márcio José Batista
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Paiva, Moises Marques
Costa Filho, Evilasio Anisio
Santos, Bruna Giovanna Barbosa dos
Santos, Kleilton Oliveira
Sousa, Wladymyr Jefferson Bacalhau de
Assis Júnior, Pedro Carlos de
Cardoso, Márcio José Batista
dc.subject.por.fl_str_mv Quitosano
Polivinilpirrolidona
Viscosidad
Mejoramiento
Mezclas.
Chitosan
Polyvinylpyrrolidone
Viscosity
Optimization
Mixtures.
Quitosana
Polivinilpirrolidona
Viscosidade
Otimização
Misturas.
topic Quitosano
Polivinilpirrolidona
Viscosidad
Mejoramiento
Mezclas.
Chitosan
Polyvinylpyrrolidone
Viscosity
Optimization
Mixtures.
Quitosana
Polivinilpirrolidona
Viscosidade
Otimização
Misturas.
description Polyvinylpyrrolidone and chitosan biopolymers are biomaterials used in wound treatment, due to their biological, physicochemical, and other properties, in addition to their processability. Controlling the viscosity of polymers is of fundamental importance for processing and consequently for the properties of membranes, such as adhesiveness, crucial for medical applications in wounds. In this sense, the research proposal was to simulate and evaluate the viscosity of polymeric mixtures of medium molar mass (QM) chitosan and polyvinylpyrrolidone (PVP) in different concentrations and proportions for the synthesis of adhesive membranes. To this end, the viscosity of pure polymers was evaluated in the literature, a linear model for the viscosity of the mixtures was simulated and, subsequently, the response surface methodology (MSR) was applied using the central composite model, for three QM/PVP ratios at different concentrations of the solutions. The viscosity of QM and PVP polymers present an exponential growth trend line, based on literature data, having a satisfactory regression coefficient, and the linear simulation model for viscosity of the mixtures, proved to be satisfactory, considering a variation of 5%. The surface response and contour graphs make evident the effect of solution concentration and polymer mix ratio, and in which mixing situations it is possible to achieve higher and lower viscosity levels. The information obtained in the research is extremely useful, aiding in the development of polymeric mixtures, in order to seek the best conditions, reduce the time of experiments focusing on points of interest.
publishDate 2021
dc.date.none.fl_str_mv 2021-10-22
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/21348
10.33448/rsd-v10i13.21348
url https://rsdjournal.org/index.php/rsd/article/view/21348
identifier_str_mv 10.33448/rsd-v10i13.21348
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/21348/19273
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 13; e373101321348
Research, Society and Development; Vol. 10 Núm. 13; e373101321348
Research, Society and Development; v. 10 n. 13; e373101321348
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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