Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/21348 |
Resumo: | Polyvinylpyrrolidone and chitosan biopolymers are biomaterials used in wound treatment, due to their biological, physicochemical, and other properties, in addition to their processability. Controlling the viscosity of polymers is of fundamental importance for processing and consequently for the properties of membranes, such as adhesiveness, crucial for medical applications in wounds. In this sense, the research proposal was to simulate and evaluate the viscosity of polymeric mixtures of medium molar mass (QM) chitosan and polyvinylpyrrolidone (PVP) in different concentrations and proportions for the synthesis of adhesive membranes. To this end, the viscosity of pure polymers was evaluated in the literature, a linear model for the viscosity of the mixtures was simulated and, subsequently, the response surface methodology (MSR) was applied using the central composite model, for three QM/PVP ratios at different concentrations of the solutions. The viscosity of QM and PVP polymers present an exponential growth trend line, based on literature data, having a satisfactory regression coefficient, and the linear simulation model for viscosity of the mixtures, proved to be satisfactory, considering a variation of 5%. The surface response and contour graphs make evident the effect of solution concentration and polymer mix ratio, and in which mixing situations it is possible to achieve higher and lower viscosity levels. The information obtained in the research is extremely useful, aiding in the development of polymeric mixtures, in order to seek the best conditions, reduce the time of experiments focusing on points of interest. |
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Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processingModelado de viscosidad en mezcla de polivinilpirrolidona/quitosano para procesamiento de membranas adhesivasModelagem da viscosidade em mistura polivinilpirrolidona/quitosana para processamento de membrana adesivaQuitosanoPolivinilpirrolidonaViscosidadMejoramientoMezclas.ChitosanPolyvinylpyrrolidoneViscosityOptimizationMixtures.QuitosanaPolivinilpirrolidonaViscosidadeOtimizaçãoMisturas.Polyvinylpyrrolidone and chitosan biopolymers are biomaterials used in wound treatment, due to their biological, physicochemical, and other properties, in addition to their processability. Controlling the viscosity of polymers is of fundamental importance for processing and consequently for the properties of membranes, such as adhesiveness, crucial for medical applications in wounds. In this sense, the research proposal was to simulate and evaluate the viscosity of polymeric mixtures of medium molar mass (QM) chitosan and polyvinylpyrrolidone (PVP) in different concentrations and proportions for the synthesis of adhesive membranes. To this end, the viscosity of pure polymers was evaluated in the literature, a linear model for the viscosity of the mixtures was simulated and, subsequently, the response surface methodology (MSR) was applied using the central composite model, for three QM/PVP ratios at different concentrations of the solutions. The viscosity of QM and PVP polymers present an exponential growth trend line, based on literature data, having a satisfactory regression coefficient, and the linear simulation model for viscosity of the mixtures, proved to be satisfactory, considering a variation of 5%. The surface response and contour graphs make evident the effect of solution concentration and polymer mix ratio, and in which mixing situations it is possible to achieve higher and lower viscosity levels. The information obtained in the research is extremely useful, aiding in the development of polymeric mixtures, in order to seek the best conditions, reduce the time of experiments focusing on points of interest.Los biopolímeros de polivinilpirrolidona y quitosano son biomateriales utilizados en el tratamiento de heridas, debido a sus propiedades biológicas, fisicoquímicas y otras, además de su procesabilidad. El control de la viscosidad de los polímeros es de fundamental importancia para el procesamiento y, en consecuencia, para las propiedades de las membranas, como la adhesividad, crucial para aplicaciones médicas en heridas. En este sentido, la propuesta de investigación fue simular y evaluar la viscosidad de mezclas poliméricas de quitosano de masa molar media (QM) y polivinilpirrolidona (PVP) en diferentes concentraciones y proporciones para la síntesis de membranas adhesivas. Para ello, se evaluó en la literatura la viscosidad de polímeros puros, se simuló un modelo lineal para la viscosidad de las mezclas y, posteriormente, se aplicó la metodología de superficie de respuesta (MSR) utilizando el modelo compuesto central, para tres QM / PVP proporciones a diferentes concentraciones de las soluciones. La viscosidad de los polímeros QM y PVP presenta una línea de tendencia de crecimiento exponencial, con base en los datos de la literatura, teniendo un coeficiente de regresión satisfactorio, y el modelo de simulación lineal para la viscosidad de las mezclas, resultó satisfactorio, considerando una variación del 5%. La respuesta de la superficie y los gráficos de contorno hacen evidente el efecto de la concentración de la solución y la relación de mezcla del polímero, y en qué situaciones de mezcla es posible lograr niveles de viscosidad más altos y más bajos. La información obtenida en la investigación es sumamente útil, ayudando en el desarrollo de mezclas poliméricas, con el fin de buscar las mejores condiciones, reducir el tiempo de experimentos enfocados en puntos de interés.Os biopolímeros polivinilpirrolidona e quitosana são biomateriais utilizados no tratamento de feridas, devido suas propriedades biológicas, físico-química entre outras, além de sua processabilidade. O controle da viscosidade dos polímeros é de fundamental importância para o processamento e consequentemente das propriedades das membranas, como a adesividade, crucial para aplicações de médicas em feridas. Nesse sentido, a proposta da pesquisa foi simular e avaliar a viscosidade de misturas poliméricas de quitosana de média massa molar (QM) e polivinilpirrolidona (PVP) em diferentes concentrações e proporções para síntese de membranas adesivas. Para tal, foi avaliado na literatura a viscosidade dos polímeros puros, simulado um modelo linear para viscosidade das misturas e, posteriormente, aplicado a metodologia de superfície de resposta (MSR) utilizando o modelo composto central, para três proporções QM/PVP em diferentes concentrações das soluções. A viscosidade dos polímeros QM e o PVP apresentam uma linha de tendência de crescimento exponencial, com baseado em dados da literatura, tendo um coeficiente de regressão satisfatório, e o modelo linear de simulação para viscosidade das misturas, demonstrou ser satisfatórios, considerando uma variação de 5%. Os gráficos de superfície resposta e contorno deixam evidentes o efeito da concentração da solução e proporção de mistura polimérica, e em quais situações de mistura é possível atingir níveis mais elevados e reduzidos da viscosidade. As informações obtidas na pesquisa são extremamente úteis, auxiliando no desenvolvimento das misturas poliméricas, de forma, a buscar as melhores condições, reduzir tempo de experimentos focando pontos de interesse.Research, Society and Development2021-10-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2134810.33448/rsd-v10i13.21348Research, Society and Development; Vol. 10 No. 13; e373101321348Research, Society and Development; Vol. 10 Núm. 13; e373101321348Research, Society and Development; v. 10 n. 13; e3731013213482525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/21348/19273Copyright (c) 2021 Moises Marques Paiva; Evilasio Anisio Costa Filho; Bruna Giovanna Barbosa dos Santos; Kleilton Oliveira Santos; Wladymyr Jefferson Bacalhau de Sousa; Pedro Carlos de Assis Júnior; Márcio José Batista Cardosohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPaiva, Moises Marques Costa Filho, Evilasio Anisio Santos, Bruna Giovanna Barbosa dos Santos, Kleilton Oliveira Sousa, Wladymyr Jefferson Bacalhau de Assis Júnior, Pedro Carlos de Cardoso, Márcio José Batista 2021-11-21T18:26:28Zoai:ojs.pkp.sfu.ca:article/21348Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:40:46.935191Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing Modelado de viscosidad en mezcla de polivinilpirrolidona/quitosano para procesamiento de membranas adhesivas Modelagem da viscosidade em mistura polivinilpirrolidona/quitosana para processamento de membrana adesiva |
title |
Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing |
spellingShingle |
Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing Paiva, Moises Marques Quitosano Polivinilpirrolidona Viscosidad Mejoramiento Mezclas. Chitosan Polyvinylpyrrolidone Viscosity Optimization Mixtures. Quitosana Polivinilpirrolidona Viscosidade Otimização Misturas. |
title_short |
Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing |
title_full |
Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing |
title_fullStr |
Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing |
title_full_unstemmed |
Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing |
title_sort |
Viscosity modeling in polyvinylpyrrolidone/chitosan blend for adhesive membrane processing |
author |
Paiva, Moises Marques |
author_facet |
Paiva, Moises Marques Costa Filho, Evilasio Anisio Santos, Bruna Giovanna Barbosa dos Santos, Kleilton Oliveira Sousa, Wladymyr Jefferson Bacalhau de Assis Júnior, Pedro Carlos de Cardoso, Márcio José Batista |
author_role |
author |
author2 |
Costa Filho, Evilasio Anisio Santos, Bruna Giovanna Barbosa dos Santos, Kleilton Oliveira Sousa, Wladymyr Jefferson Bacalhau de Assis Júnior, Pedro Carlos de Cardoso, Márcio José Batista |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Paiva, Moises Marques Costa Filho, Evilasio Anisio Santos, Bruna Giovanna Barbosa dos Santos, Kleilton Oliveira Sousa, Wladymyr Jefferson Bacalhau de Assis Júnior, Pedro Carlos de Cardoso, Márcio José Batista |
dc.subject.por.fl_str_mv |
Quitosano Polivinilpirrolidona Viscosidad Mejoramiento Mezclas. Chitosan Polyvinylpyrrolidone Viscosity Optimization Mixtures. Quitosana Polivinilpirrolidona Viscosidade Otimização Misturas. |
topic |
Quitosano Polivinilpirrolidona Viscosidad Mejoramiento Mezclas. Chitosan Polyvinylpyrrolidone Viscosity Optimization Mixtures. Quitosana Polivinilpirrolidona Viscosidade Otimização Misturas. |
description |
Polyvinylpyrrolidone and chitosan biopolymers are biomaterials used in wound treatment, due to their biological, physicochemical, and other properties, in addition to their processability. Controlling the viscosity of polymers is of fundamental importance for processing and consequently for the properties of membranes, such as adhesiveness, crucial for medical applications in wounds. In this sense, the research proposal was to simulate and evaluate the viscosity of polymeric mixtures of medium molar mass (QM) chitosan and polyvinylpyrrolidone (PVP) in different concentrations and proportions for the synthesis of adhesive membranes. To this end, the viscosity of pure polymers was evaluated in the literature, a linear model for the viscosity of the mixtures was simulated and, subsequently, the response surface methodology (MSR) was applied using the central composite model, for three QM/PVP ratios at different concentrations of the solutions. The viscosity of QM and PVP polymers present an exponential growth trend line, based on literature data, having a satisfactory regression coefficient, and the linear simulation model for viscosity of the mixtures, proved to be satisfactory, considering a variation of 5%. The surface response and contour graphs make evident the effect of solution concentration and polymer mix ratio, and in which mixing situations it is possible to achieve higher and lower viscosity levels. The information obtained in the research is extremely useful, aiding in the development of polymeric mixtures, in order to seek the best conditions, reduce the time of experiments focusing on points of interest. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-10-22 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/21348 10.33448/rsd-v10i13.21348 |
url |
https://rsdjournal.org/index.php/rsd/article/view/21348 |
identifier_str_mv |
10.33448/rsd-v10i13.21348 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/21348/19273 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 13; e373101321348 Research, Society and Development; Vol. 10 Núm. 13; e373101321348 Research, Society and Development; v. 10 n. 13; e373101321348 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052756807122944 |