The pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus and the influence on patient prognosis: A literature review
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/40489 |
Resumo: | Introduction: The pandemic of COVID-19 shook the foundations of modern societies, bringing numerous questions about its functioning, which should be analyzed, especially by the interrelation with chronic diseases such as Diabetes. Objective: This study aimed to evaluate the pathogenic convergence points between SARS-CoV-2 infection and Type 2 Diabetes Mellitus, as well as the effect on patient prognosis. Materials and Methods: This is an integrative literature review about the pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus. The PICO strategy was used to develop the guiding question. Moreover, the descriptors "COVID-19"; "Diabetes Mellitus"; "Physiology" were cross-referenced with the National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (SCIELO), Ebscohost, Google Scholar, and Virtual Health Library (VHL) databases. Results and Discussion: A significant portion of the articles indicated an interrelationship between the pathophysiological mechanisms of COVID-19 and Type 2 Diabetes Mellitus, especially in the exacerbation of the immune response and direct damage to pancreatic cells, which result in a worse prognosis of the viral infection. Conclusion: It was possible to notice that both diseases have pathogenic interaction points, reinforcing the need to re-signify the health-disease process, aiming to understand the proper functioning of the pathophysiological mechanisms of each one of them. |
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The pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus and the influence on patient prognosis: A literature reviewLa integración fisiopatológica entre la COVID-19 y la diabetes mellitus de tipo 2 y su influencia em el pronóstico de los pacientes: Revisión bibliográficaA integração fisiopatológica entre a COVID-19 e o Diabetes Mellitus Tipo 2 e a influência sobre o prognóstico dos pacientes: Uma revisão de literaturaCOVID-19DiabetesPhysiology.COVID-19DiabetesFisiopatología.COVID-19DiabetesFisiopatologia.Introduction: The pandemic of COVID-19 shook the foundations of modern societies, bringing numerous questions about its functioning, which should be analyzed, especially by the interrelation with chronic diseases such as Diabetes. Objective: This study aimed to evaluate the pathogenic convergence points between SARS-CoV-2 infection and Type 2 Diabetes Mellitus, as well as the effect on patient prognosis. Materials and Methods: This is an integrative literature review about the pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus. The PICO strategy was used to develop the guiding question. Moreover, the descriptors "COVID-19"; "Diabetes Mellitus"; "Physiology" were cross-referenced with the National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (SCIELO), Ebscohost, Google Scholar, and Virtual Health Library (VHL) databases. Results and Discussion: A significant portion of the articles indicated an interrelationship between the pathophysiological mechanisms of COVID-19 and Type 2 Diabetes Mellitus, especially in the exacerbation of the immune response and direct damage to pancreatic cells, which result in a worse prognosis of the viral infection. Conclusion: It was possible to notice that both diseases have pathogenic interaction points, reinforcing the need to re-signify the health-disease process, aiming to understand the proper functioning of the pathophysiological mechanisms of each one of them.Introducción: La pandemia de COVID-19 sacudió los cimientos de las sociedades modernas, trayendo numerosos interrogantes sobre su funcionamiento, que deben ser analizados, especialmente por la interrelación con enfermedades crónicas como la Diabetes. Objetivo: El presente estudio se propuso evaluar los puntos de convergencia patogénica entre la infección por SARS-CoV-2 y la diabetes mellitus de tipo 2, así como el efecto sobre el pronóstico de los pacientes. Materiales y Métodos: Se trata de una revisión bibliográfica integradora sobre la integración fisiopatológica entre la COVID-19 y la Diabetes Mellitus Tipo 2. Se utilizó la estrategia PICO para desarrollar la pregunta guía. Además, se realizó el cruce de los descriptores "COVID-19"; "Diabetes Mellitus"; "Fisiologia", en las bases de datos National Library of Medicine (PubMed MEDLINE), Scientific Eletronic Library Online (SCIELO), Ebscohost, Google Scholar y Biblioteca Virtual de Salud (BVS). Resultados y Discusión: Una parte significativa de los artículos indicaron una interrelación entre los mecanismos fisiopatológicos de la COVID-19 y la Diabetes Mellitus Tipo 2, especialmente en la exacerbación de la respuesta inmune y el daño directo a las células pancreáticas, que resultan en un peor pronóstico de la infección viral. Conclusión: Se pudo observar que las dos enfermedades tienen puntos de interacción patogénica, reforzando la necesidad de resignificar el proceso salud-enfermedad, buscando comprender el correcto funcionamiento de los mecanismos fisiopatológicos de cada una de ellas.Introdução: A pandemia da COVID-19 abalou os alicerces das sociedades modernas, trazendo inúmeros questionamentos acerca do seu funcionamento, os quais devem ser analisados, sobretudo pela interrelação com doenças crônicas, como o Diabetes. Objetivo: O presente estudo teve como objetivo avaliar os pontos de convergência patogênica entre a infecção pelo SARS-CoV-2 e o Diabetes Mellitus Tipo 2, bem como o efeito sobre o prognóstico dos pacientes. Materiais e Métodos: Trata-se de uma revisão integrativa de literatura acerca da integração fisiopatológica entre a COVID-19 e o Diabetes Mellitus Tipo 2. Utilizou-se a estratégia PICO para a elaboração da pergunta norteadora. Ademais, realizou-se o cruzamento dos descritores “COVID-19”; “Diabetes Mellitus”; “Fisiologia”, nas bases de dados National Library of Medicine (PubMed MEDLINE), Scientific Eletronic Library Online (SCIELO), Ebscohost, Google Scholar e Biblioteca Virtual de Saúde (BVS). Resultados e Discussão: Uma parcela significativa dos artigos indicou uma interrelação entre os mecanismos fisiopatológicos da COVID-19 e o Diabetes Mellitus Tipo 2, sobretudo na exacerbação da resposta imune e dos danos diretos às células pancreáticas, os quais resultam em pior prognóstico da infecção viral. Conclusão: Foi possível perceber que as duas doenças possuem pontos de interação patogênica, reforçando a necessidade de ressignificar o processo de saúde-doença, objetivando compreender o funcionamento adequado dos mecanismos fisiopatológicos próprios de cada uma delas.Research, Society and Development2023-02-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4048910.33448/rsd-v12i3.40489Research, Society and Development; Vol. 12 No. 3; e5212340489Research, Society and Development; Vol. 12 Núm. 3; e5212340489Research, Society and Development; v. 12 n. 3; e52123404892525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/40489/33031Copyright (c) 2023 Giovanna Leone Silva Guedes; Heitor Machado; Beatriz Carnevalli Motta Nunes; Ana Carolina Resende Caldeira; Maria Eduarda Maia Fernandes ; Julia Messias Murad; Carolina Teixeira Capellini; Luiza Garcia de Luca; Maria Fernanda Marques Cardenas; Marilene Rivany Nuneshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGuedes, Giovanna Leone Silva Machado, HeitorNunes, Beatriz Carnevalli Motta Caldeira, Ana Carolina Resende Fernandes , Maria Eduarda Maia Murad, Julia Messias Capellini, Carolina Teixeira Luca, Luiza Garcia de Cardenas, Maria Fernanda Marques Nunes, Marilene Rivany 2023-03-23T08:33:38Zoai:ojs.pkp.sfu.ca:article/40489Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2023-03-23T08:33:38Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
The pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus and the influence on patient prognosis: A literature review La integración fisiopatológica entre la COVID-19 y la diabetes mellitus de tipo 2 y su influencia em el pronóstico de los pacientes: Revisión bibliográfica A integração fisiopatológica entre a COVID-19 e o Diabetes Mellitus Tipo 2 e a influência sobre o prognóstico dos pacientes: Uma revisão de literatura |
title |
The pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus and the influence on patient prognosis: A literature review |
spellingShingle |
The pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus and the influence on patient prognosis: A literature review Guedes, Giovanna Leone Silva COVID-19 Diabetes Physiology. COVID-19 Diabetes Fisiopatología. COVID-19 Diabetes Fisiopatologia. |
title_short |
The pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus and the influence on patient prognosis: A literature review |
title_full |
The pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus and the influence on patient prognosis: A literature review |
title_fullStr |
The pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus and the influence on patient prognosis: A literature review |
title_full_unstemmed |
The pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus and the influence on patient prognosis: A literature review |
title_sort |
The pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus and the influence on patient prognosis: A literature review |
author |
Guedes, Giovanna Leone Silva |
author_facet |
Guedes, Giovanna Leone Silva Machado, Heitor Nunes, Beatriz Carnevalli Motta Caldeira, Ana Carolina Resende Fernandes , Maria Eduarda Maia Murad, Julia Messias Capellini, Carolina Teixeira Luca, Luiza Garcia de Cardenas, Maria Fernanda Marques Nunes, Marilene Rivany |
author_role |
author |
author2 |
Machado, Heitor Nunes, Beatriz Carnevalli Motta Caldeira, Ana Carolina Resende Fernandes , Maria Eduarda Maia Murad, Julia Messias Capellini, Carolina Teixeira Luca, Luiza Garcia de Cardenas, Maria Fernanda Marques Nunes, Marilene Rivany |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Guedes, Giovanna Leone Silva Machado, Heitor Nunes, Beatriz Carnevalli Motta Caldeira, Ana Carolina Resende Fernandes , Maria Eduarda Maia Murad, Julia Messias Capellini, Carolina Teixeira Luca, Luiza Garcia de Cardenas, Maria Fernanda Marques Nunes, Marilene Rivany |
dc.subject.por.fl_str_mv |
COVID-19 Diabetes Physiology. COVID-19 Diabetes Fisiopatología. COVID-19 Diabetes Fisiopatologia. |
topic |
COVID-19 Diabetes Physiology. COVID-19 Diabetes Fisiopatología. COVID-19 Diabetes Fisiopatologia. |
description |
Introduction: The pandemic of COVID-19 shook the foundations of modern societies, bringing numerous questions about its functioning, which should be analyzed, especially by the interrelation with chronic diseases such as Diabetes. Objective: This study aimed to evaluate the pathogenic convergence points between SARS-CoV-2 infection and Type 2 Diabetes Mellitus, as well as the effect on patient prognosis. Materials and Methods: This is an integrative literature review about the pathophysiological integration between COVID-19 and Type 2 Diabetes Mellitus. The PICO strategy was used to develop the guiding question. Moreover, the descriptors "COVID-19"; "Diabetes Mellitus"; "Physiology" were cross-referenced with the National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (SCIELO), Ebscohost, Google Scholar, and Virtual Health Library (VHL) databases. Results and Discussion: A significant portion of the articles indicated an interrelationship between the pathophysiological mechanisms of COVID-19 and Type 2 Diabetes Mellitus, especially in the exacerbation of the immune response and direct damage to pancreatic cells, which result in a worse prognosis of the viral infection. Conclusion: It was possible to notice that both diseases have pathogenic interaction points, reinforcing the need to re-signify the health-disease process, aiming to understand the proper functioning of the pathophysiological mechanisms of each one of them. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-02-21 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/40489 10.33448/rsd-v12i3.40489 |
url |
https://rsdjournal.org/index.php/rsd/article/view/40489 |
identifier_str_mv |
10.33448/rsd-v12i3.40489 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/40489/33031 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 12 No. 3; e5212340489 Research, Society and Development; Vol. 12 Núm. 3; e5212340489 Research, Society and Development; v. 12 n. 3; e5212340489 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052619596759040 |