Comprehensive medication management of kidney transplanted patients
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/26224 |
Resumo: | Kidney transplant patients use several medications, which increases the risk of developing drug-related problems. This is a pre-post-intervention study, carried out in a transplant outpatient clinic in Belo Horizonte, Minas Gerais, Brazil, with post-transplant patients using tacrolimus. Pharmacy consultations were carried out in individual offices, and the initial and final status were measured between the first and the last consultation. Satisfaction with the pharmaceutical service was also assessed. Thirty-nine drug-related problems were identified, 64.3% of patients presenting at least one, of which 79.5% were resolved (p<0.001). The most frequent were “use of unnecessary medications” (26.5%), with omeprazole being the most prescribed medication for this situation. Polymedicated patients had more drug-related problems (p = 0.001). 49 interventions were performed, 51.02% were accepted. The most accepted interventions were recommendations for guidelines regarding the time of administration and reduction of adverse drug reactions (100%) and suspension of treatment (92.3%). In the end, the proportion of patients with stable clinical status increased from 35 .7% to 83.3% (p<0.001). Patients related the pharmaceutical service as very good, reporting the desire for its continuity. Comprehensive medication management positively impacted the patient's clinical situation, proved to be effective in solving drug-related problems, and was very well evaluated by the patients. It is recommended that polymedication is a priority criterion for this service. |
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Comprehensive medication management of kidney transplanted patientsManejo de la farmacoterapia en receptores de trasplante de riñónGerenciamento da terapia medicamentosa em transplantados renaisTransplante renalServiços farmacêuticosGerenciamento da terapia medicamentosaSatisfação do pacienteProblemas relacionados ao uso de medicamentos.Trasplante de riñónServicios farmacéuticosSatisfacción del pacienteProblemas relacionados con los medicamentos.Kidney transplantationPharmaceutical servicesMedication therapy managementPatient satisfactionDrug related problems.Kidney transplant patients use several medications, which increases the risk of developing drug-related problems. This is a pre-post-intervention study, carried out in a transplant outpatient clinic in Belo Horizonte, Minas Gerais, Brazil, with post-transplant patients using tacrolimus. Pharmacy consultations were carried out in individual offices, and the initial and final status were measured between the first and the last consultation. Satisfaction with the pharmaceutical service was also assessed. Thirty-nine drug-related problems were identified, 64.3% of patients presenting at least one, of which 79.5% were resolved (p<0.001). The most frequent were “use of unnecessary medications” (26.5%), with omeprazole being the most prescribed medication for this situation. Polymedicated patients had more drug-related problems (p = 0.001). 49 interventions were performed, 51.02% were accepted. The most accepted interventions were recommendations for guidelines regarding the time of administration and reduction of adverse drug reactions (100%) and suspension of treatment (92.3%). In the end, the proportion of patients with stable clinical status increased from 35 .7% to 83.3% (p<0.001). Patients related the pharmaceutical service as very good, reporting the desire for its continuity. Comprehensive medication management positively impacted the patient's clinical situation, proved to be effective in solving drug-related problems, and was very well evaluated by the patients. It is recommended that polymedication is a priority criterion for this service.Los pacientes con trasplante de riñón usan varios medicamentos, lo que aumenta el riesgo de desarrollar problemas relacionados con los medicamentos. Se trata de un estudio pre-postintervención, realizado en un ambulatorio de trasplantes en Belo Horizonte, Minas Gerais, Brasil, con pacientes postrasplante que utilizan tacrolimus. Las consultas farmaceuticas se realizaron en consultorios individuales y se midió el estado inicial y final entre la primera y la última consulta. También se evaluó la satisfacción con el servicio farmacéutico. Se identificaron 39 problemas relacionados con el fármaco, el 64,3% de los pacientes presentó al menos uno, de los cuales se resolvió el 79,5% (p <0,001). Los más frecuentes fueron el “uso de medicamentos innecesarios” (26,5%), siendo el omeprazol el medicamento más prescrito para esta situación. Los pacientes polimedicados tenían más problemas relacionados con los fármacos (p = 0,001). Se realizaron 49 intervenciones, se aceptaron el 51,02%. Las intervenciones más aceptadas fueron las recomendaciones de guías en cuanto al tiempo de administración y reducción de reacciones adversas a medicamentos (100%) y suspensión del tratamiento (92,3%). La proporción de pacientes con estado clínico estable pasó de 35,7% al 83,3% (p <0,001). Los pacientes calificaron el servicio farmacéutico como muy bueno, informando el deseo de su continuidad. El manejo de la terapia con medicamentos tuvo un impacto positivo en la situación clínica del paciente, demostró ser eficaz para resolver los problemas relacionados con los medicamentos y fue muy bien evaluado por el grupo. Se recomienda que la polimedicación sea un criterio prioritario para este servicio.Pacientes transplantados renais utilizam diversos medicamentos, o que aumenta o risco de desenvolver problemas relacionados a medicamentos. Trata-se de um estudo pré-pós-intervenção, realizado em um ambulatório de transplantes em Belo Horizonte, Minas Gerais, Brasil, como pacientes no pós-transplante e em uso de tacrolimo. As consultas farmacêuticas foram realizadas em consultórios individuais, sendo que estado inicial e final foram medidos entre a primeira e a última consulta. A satisfação com o serviço farmacêutico também foi avaliada. Foram identificados 39 problemas relacionados a medicamentos, 64,3% dos pacientes apresentando pelo menos um, dos quais 79,5% foram resolvidos (p <0,001). Os mais frequentes foram “uso de medicamentos desnecessários” (26,5%), sendo o omeprazol o medicamento mais prescrito para essa situação. Os pacientes polimedicados apresentaram mais problemas relacionados ao medicamento (p = 0,001). Foram realizadas 49 intervenções, 51,02% foram aceitas. As intervenções mais aceitas foram recomendações de orientações quanto ao tempo de administração e redução de reação adversa medicamentosa (100%) e suspensão do tratamento (92,3%). Ao final, a proporção de pacientes com quadro clínico estável a condição aumentou de 35,7% para 83,3% (p <0,001). Os pacientes avaliaram o atendimento farmacêutico como muito bom, relatando o desejo de sua continuidade. O gerenciamento da terapia medicamentosa impactou positivamente na situação clínica do paciente, demonstrou ser eficaz na resolução de problemas relacionados a medicamentos e foi muito bem avaliado pelos paciente. Recomenda-se que a polimedicação seja critério prioritário para a implantação do gerenciamento da terapia medicamentosa.Research, Society and Development2022-02-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2622410.33448/rsd-v11i2.26224Research, Society and Development; Vol. 11 No. 2; e49511226224Research, Society and Development; Vol. 11 Núm. 2; e49511226224Research, Society and Development; v. 11 n. 2; e495112262242525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/26224/22801Copyright (c) 2022 Patrícia Mara dos Reis; Isabela Diniz de Oliveira; Pollyanne Lacerda Coelho ; Sílvia Novaes Dias ; Luana Kellen de Oliveira Silva ; Clarice Chemellohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessReis, Patrícia Mara dosOliveira, Isabela Diniz de Coelho , Pollyanne Lacerda Dias , Sílvia Novaes Silva , Luana Kellen de Oliveira Chemello, Clarice2022-02-07T01:42:50Zoai:ojs.pkp.sfu.ca:article/26224Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:19.221898Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Comprehensive medication management of kidney transplanted patients Manejo de la farmacoterapia en receptores de trasplante de riñón Gerenciamento da terapia medicamentosa em transplantados renais |
title |
Comprehensive medication management of kidney transplanted patients |
spellingShingle |
Comprehensive medication management of kidney transplanted patients Reis, Patrícia Mara dos Transplante renal Serviços farmacêuticos Gerenciamento da terapia medicamentosa Satisfação do paciente Problemas relacionados ao uso de medicamentos. Trasplante de riñón Servicios farmacéuticos Satisfacción del paciente Problemas relacionados con los medicamentos. Kidney transplantation Pharmaceutical services Medication therapy management Patient satisfaction Drug related problems. |
title_short |
Comprehensive medication management of kidney transplanted patients |
title_full |
Comprehensive medication management of kidney transplanted patients |
title_fullStr |
Comprehensive medication management of kidney transplanted patients |
title_full_unstemmed |
Comprehensive medication management of kidney transplanted patients |
title_sort |
Comprehensive medication management of kidney transplanted patients |
author |
Reis, Patrícia Mara dos |
author_facet |
Reis, Patrícia Mara dos Oliveira, Isabela Diniz de Coelho , Pollyanne Lacerda Dias , Sílvia Novaes Silva , Luana Kellen de Oliveira Chemello, Clarice |
author_role |
author |
author2 |
Oliveira, Isabela Diniz de Coelho , Pollyanne Lacerda Dias , Sílvia Novaes Silva , Luana Kellen de Oliveira Chemello, Clarice |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Reis, Patrícia Mara dos Oliveira, Isabela Diniz de Coelho , Pollyanne Lacerda Dias , Sílvia Novaes Silva , Luana Kellen de Oliveira Chemello, Clarice |
dc.subject.por.fl_str_mv |
Transplante renal Serviços farmacêuticos Gerenciamento da terapia medicamentosa Satisfação do paciente Problemas relacionados ao uso de medicamentos. Trasplante de riñón Servicios farmacéuticos Satisfacción del paciente Problemas relacionados con los medicamentos. Kidney transplantation Pharmaceutical services Medication therapy management Patient satisfaction Drug related problems. |
topic |
Transplante renal Serviços farmacêuticos Gerenciamento da terapia medicamentosa Satisfação do paciente Problemas relacionados ao uso de medicamentos. Trasplante de riñón Servicios farmacéuticos Satisfacción del paciente Problemas relacionados con los medicamentos. Kidney transplantation Pharmaceutical services Medication therapy management Patient satisfaction Drug related problems. |
description |
Kidney transplant patients use several medications, which increases the risk of developing drug-related problems. This is a pre-post-intervention study, carried out in a transplant outpatient clinic in Belo Horizonte, Minas Gerais, Brazil, with post-transplant patients using tacrolimus. Pharmacy consultations were carried out in individual offices, and the initial and final status were measured between the first and the last consultation. Satisfaction with the pharmaceutical service was also assessed. Thirty-nine drug-related problems were identified, 64.3% of patients presenting at least one, of which 79.5% were resolved (p<0.001). The most frequent were “use of unnecessary medications” (26.5%), with omeprazole being the most prescribed medication for this situation. Polymedicated patients had more drug-related problems (p = 0.001). 49 interventions were performed, 51.02% were accepted. The most accepted interventions were recommendations for guidelines regarding the time of administration and reduction of adverse drug reactions (100%) and suspension of treatment (92.3%). In the end, the proportion of patients with stable clinical status increased from 35 .7% to 83.3% (p<0.001). Patients related the pharmaceutical service as very good, reporting the desire for its continuity. Comprehensive medication management positively impacted the patient's clinical situation, proved to be effective in solving drug-related problems, and was very well evaluated by the patients. It is recommended that polymedication is a priority criterion for this service. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-02-03 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26224 10.33448/rsd-v11i2.26224 |
url |
https://rsdjournal.org/index.php/rsd/article/view/26224 |
identifier_str_mv |
10.33448/rsd-v11i2.26224 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26224/22801 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 2; e49511226224 Research, Society and Development; Vol. 11 Núm. 2; e49511226224 Research, Society and Development; v. 11 n. 2; e49511226224 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052704659341312 |