Evaluation of antioxidant activity and toxicity in Artemia salina of the ether extract and fractions from Tecoma stans seeds

Detalhes bibliográficos
Autor(a) principal: Azevedo, Lucas Santos
Data de Publicação: 2021
Outros Autores: Gonçalves, Thaís Paula Rodrigues, Amado, Paula Avelar, Lima, Luciana Alves Rodrigues dos Santos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/17829
Resumo: Tecoma stans (L.) Juss. Ex Kunth is a species belonging to the Bignoniaceae family, popularly known as yellowing, yellow bell, and garden little ipe. Studies with T. stans seeds are scarce and it have potential in the search for natural compounds with biological activities. This study aimed to evaluate the toxicity and antioxidant activity of the ether extract (EE) and fractions from T. stans seeds. The EE was obtained in Soxhlet apparatus with petroleum ether and fractions were obtained by hydrolysis and esterification reactions. Phytochemical screening evaluated the presence of steroids, triterpenoids, alkaloids, coumarins and anthraquinones in EE. The toxicity was evaluated by the A. salina lethality test and antioxidant activity by DPPH method. It was observed the presence of steroids, triterpenoids and alkaloids in EE, which had no toxicity to A. salina (LC50 > 1000 µg/mL). The fractions of seeds exhibited toxicity on A. salina. All samples showed antioxidant activity with EC50 between 0.9 and 1.1 µg/mL. These results indicated potential applications for T. stans seeds.
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spelling Evaluation of antioxidant activity and toxicity in Artemia salina of the ether extract and fractions from Tecoma stans seeds Evaluación de la actividad antioxidante y la toxicidad en Artemia salina a partir de extracto etéreo y fracciones de semillas de Tecoma stansAvaliação da atividade antioxidante e toxicidade em Artemia salina do extrato etéreo e frações de sementes de Tecoma stansTecoma stansMetabólitos secundáriosAtividade antioxidanteArtemia salina.Tecoma stansSecondary metabolitesAntioxidant activityBrine shrimp.Tecoma stansMetabolitos secundariosActividad antioxidanteCamarón de salmuera.Tecoma stans (L.) Juss. Ex Kunth is a species belonging to the Bignoniaceae family, popularly known as yellowing, yellow bell, and garden little ipe. Studies with T. stans seeds are scarce and it have potential in the search for natural compounds with biological activities. This study aimed to evaluate the toxicity and antioxidant activity of the ether extract (EE) and fractions from T. stans seeds. The EE was obtained in Soxhlet apparatus with petroleum ether and fractions were obtained by hydrolysis and esterification reactions. Phytochemical screening evaluated the presence of steroids, triterpenoids, alkaloids, coumarins and anthraquinones in EE. The toxicity was evaluated by the A. salina lethality test and antioxidant activity by DPPH method. It was observed the presence of steroids, triterpenoids and alkaloids in EE, which had no toxicity to A. salina (LC50 > 1000 µg/mL). The fractions of seeds exhibited toxicity on A. salina. All samples showed antioxidant activity with EC50 between 0.9 and 1.1 µg/mL. These results indicated potential applications for T. stans seeds.Tecoma stans (L.) Juss. Ex Kunth es una especie perteneciente a la familia Bignoniaceae, popularmente conocida como amarillamiento, campana amarilla y ipezito de jardín. Los estudios con semillas de T. stans son escasos y tienen potencial en la búsqueda de compuestos naturales con actividades biológicas. Este trabajo tuvo como objetivo evaluar la toxicidad y actividad antioxidante del extracto etéreo (EE) y fracciones de semilla de T. stans. El EE se obtuvo en un aparato Soxhlet con éter de petróleo y las fracciones se obtuvieron mediante reacciones de hidrólisis y esterificación. El cribado fitoquímico evaluó la presencia de esteroides, triterpenoides, alcaloides, cumarinas y antraquinonas en EE. La toxicidad se evaluó mediante la prueba de letalidad en A. salina y la actividad antioxidante mediante el método DPPH. En el EE se observó la presencia de esteroides, triterpenoides y alcaloides, los cuales no mostraron toxicidad para A. salina (CL50 > 1000 µg/mL). Las fracciones de EE de las semillas de T. stans mostraron toxicidad en A. salina. Todas las muestras mostraron actividad antioxidante con CE50 entre 0.9 y 1.1 µg/mL. Estos resultados indicaron aplicaciones potenciales para las semillas de T. stans.Tecoma stans (L.) Juss. Ex Kunth é uma espécie pertencente à família Bignoniaceae, popularmente conhecida como amarelinho, sino amarelo e ipezinho de jardim. Estudos com sementes de T. stans são escassos e tem potencial na busca de compostos naturais com atividades biológicas. Este trabalho teve como objetivo avaliar a toxicidade e a atividade antioxidante do extrato etéreo (EE) e frações de sementes de T. stans. EE foi obtido em aparelho de Soxhlet com éter de petróleo e as frações foram obtidas por reações de hidrólise e esterificação. A triagem fitoquímica avaliou a presença de esteroides, triterpenoides, alcaloides, cumarinas e antraquinonas no EE. A toxicidade foi avaliada pelo teste de letalidade em A. salina e a atividade antioxidante pelo método de DPPH. Foi observada a presença de esteroides, triterpenoides e alcaloides no EE, que não apresentou toxicidade para A. salina (CL50 > 1000 µg/mL). As frações do EE das sementes de T. stans exibiram toxicidade em A. salina. Todas as amostras apresentaram atividade antioxidante com CE50 entre 0,9 e 1,1 µg/mL. Esses resultados indicam potenciais aplicações para sementes de T. stans.Research, Society and Development2021-07-22info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1782910.33448/rsd-v10i9.17829Research, Society and Development; Vol. 10 No. 9; e12510917829Research, Society and Development; Vol. 10 Núm. 9; e12510917829Research, Society and Development; v. 10 n. 9; e125109178292525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/17829/15967Copyright (c) 2021 Lucas Santos Azevedo; Thaís Paula Rodrigues Gonçalves; Paula Avelar Amado; Luciana Alves Rodrigues dos Santos Limahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAzevedo, Lucas SantosGonçalves, Thaís Paula RodriguesAmado, Paula AvelarLima, Luciana Alves Rodrigues dos Santos2021-09-12T14:28:06Zoai:ojs.pkp.sfu.ca:article/17829Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:38:06.130315Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Evaluation of antioxidant activity and toxicity in Artemia salina of the ether extract and fractions from Tecoma stans seeds
Evaluación de la actividad antioxidante y la toxicidad en Artemia salina a partir de extracto etéreo y fracciones de semillas de Tecoma stans
Avaliação da atividade antioxidante e toxicidade em Artemia salina do extrato etéreo e frações de sementes de Tecoma stans
title Evaluation of antioxidant activity and toxicity in Artemia salina of the ether extract and fractions from Tecoma stans seeds
spellingShingle Evaluation of antioxidant activity and toxicity in Artemia salina of the ether extract and fractions from Tecoma stans seeds
Azevedo, Lucas Santos
Tecoma stans
Metabólitos secundários
Atividade antioxidante
Artemia salina.
Tecoma stans
Secondary metabolites
Antioxidant activity
Brine shrimp.
Tecoma stans
Metabolitos secundarios
Actividad antioxidante
Camarón de salmuera.
title_short Evaluation of antioxidant activity and toxicity in Artemia salina of the ether extract and fractions from Tecoma stans seeds
title_full Evaluation of antioxidant activity and toxicity in Artemia salina of the ether extract and fractions from Tecoma stans seeds
title_fullStr Evaluation of antioxidant activity and toxicity in Artemia salina of the ether extract and fractions from Tecoma stans seeds
title_full_unstemmed Evaluation of antioxidant activity and toxicity in Artemia salina of the ether extract and fractions from Tecoma stans seeds
title_sort Evaluation of antioxidant activity and toxicity in Artemia salina of the ether extract and fractions from Tecoma stans seeds
author Azevedo, Lucas Santos
author_facet Azevedo, Lucas Santos
Gonçalves, Thaís Paula Rodrigues
Amado, Paula Avelar
Lima, Luciana Alves Rodrigues dos Santos
author_role author
author2 Gonçalves, Thaís Paula Rodrigues
Amado, Paula Avelar
Lima, Luciana Alves Rodrigues dos Santos
author2_role author
author
author
dc.contributor.author.fl_str_mv Azevedo, Lucas Santos
Gonçalves, Thaís Paula Rodrigues
Amado, Paula Avelar
Lima, Luciana Alves Rodrigues dos Santos
dc.subject.por.fl_str_mv Tecoma stans
Metabólitos secundários
Atividade antioxidante
Artemia salina.
Tecoma stans
Secondary metabolites
Antioxidant activity
Brine shrimp.
Tecoma stans
Metabolitos secundarios
Actividad antioxidante
Camarón de salmuera.
topic Tecoma stans
Metabólitos secundários
Atividade antioxidante
Artemia salina.
Tecoma stans
Secondary metabolites
Antioxidant activity
Brine shrimp.
Tecoma stans
Metabolitos secundarios
Actividad antioxidante
Camarón de salmuera.
description Tecoma stans (L.) Juss. Ex Kunth is a species belonging to the Bignoniaceae family, popularly known as yellowing, yellow bell, and garden little ipe. Studies with T. stans seeds are scarce and it have potential in the search for natural compounds with biological activities. This study aimed to evaluate the toxicity and antioxidant activity of the ether extract (EE) and fractions from T. stans seeds. The EE was obtained in Soxhlet apparatus with petroleum ether and fractions were obtained by hydrolysis and esterification reactions. Phytochemical screening evaluated the presence of steroids, triterpenoids, alkaloids, coumarins and anthraquinones in EE. The toxicity was evaluated by the A. salina lethality test and antioxidant activity by DPPH method. It was observed the presence of steroids, triterpenoids and alkaloids in EE, which had no toxicity to A. salina (LC50 > 1000 µg/mL). The fractions of seeds exhibited toxicity on A. salina. All samples showed antioxidant activity with EC50 between 0.9 and 1.1 µg/mL. These results indicated potential applications for T. stans seeds.
publishDate 2021
dc.date.none.fl_str_mv 2021-07-22
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/17829
10.33448/rsd-v10i9.17829
url https://rsdjournal.org/index.php/rsd/article/view/17829
identifier_str_mv 10.33448/rsd-v10i9.17829
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/17829/15967
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 9; e12510917829
Research, Society and Development; Vol. 10 Núm. 9; e12510917829
Research, Society and Development; v. 10 n. 9; e12510917829
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052752304537600

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