Rhabdomyosarcoma in the urinary bladder of an American Pitbull Terrier
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/14888 |
Resumo: | Botryoid rhabdomyosarcoma is a variant of embryonic rhabdomyosarcoma and originates in striated muscle cells, or precursors of these cells, so they can start in parts of the body with the absence of striated muscle, such as the urogenital tract. Ser, the dogs affected are young up to two years old and the neoplastic masses look like a bunch of grapes. The objective of the present report was described as a case of botryoid rhabdomyosarcoma in a 16-month-old American Pittbull Terrier dog that presented a mass inside the urinary bladder, later diagnosed through histopathological and immunohistochemical examination. The mass was multilobulated, firm, pinkish to red with multifocal areas of necrosis and was adhered to the mucosa of the most cranial region of the urinary vesicle, emitting disseminated branches towards the bladder triangle. Microscopically, a neoplasm is discovered by two cell populations interspersed with a myxoid matrix, one composed of small, round cells, with scarce cytoplasm and hypercolored basophilic nucleus and the other by elongated cells, with eosinophilic and paracentral cytoplasm, both as having moderate and pleomorphism 2 mitosis figures per field (400 x). Increased cell density was observed below the bladder epithelium. A combination of complementary tests was conclusive for the diagnosis of neoplasia. |
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Rhabdomyosarcoma in the urinary bladder of an American Pitbull TerrierRabdomiosarcoma botrioide en la vejiga urinaria de un American Pittbull TerrierRabdomiossarcoma botrióide na vesícula urinária de um American Pitbull TerrierPerroNeoplasmaMúsculo estriadoSistema urinario.DogNeoplasmStriated muscleUrinary system.CãoNeoplasiaMúsculo estriadoSistema urinário.Botryoid rhabdomyosarcoma is a variant of embryonic rhabdomyosarcoma and originates in striated muscle cells, or precursors of these cells, so they can start in parts of the body with the absence of striated muscle, such as the urogenital tract. Ser, the dogs affected are young up to two years old and the neoplastic masses look like a bunch of grapes. The objective of the present report was described as a case of botryoid rhabdomyosarcoma in a 16-month-old American Pittbull Terrier dog that presented a mass inside the urinary bladder, later diagnosed through histopathological and immunohistochemical examination. The mass was multilobulated, firm, pinkish to red with multifocal areas of necrosis and was adhered to the mucosa of the most cranial region of the urinary vesicle, emitting disseminated branches towards the bladder triangle. Microscopically, a neoplasm is discovered by two cell populations interspersed with a myxoid matrix, one composed of small, round cells, with scarce cytoplasm and hypercolored basophilic nucleus and the other by elongated cells, with eosinophilic and paracentral cytoplasm, both as having moderate and pleomorphism 2 mitosis figures per field (400 x). Increased cell density was observed below the bladder epithelium. A combination of complementary tests was conclusive for the diagnosis of neoplasia.El rabdomiosarcoma botrioide es una variante del rabdomiosarcoma embrionario y se origina en las células musculares estriadas, o precursoras de estas células, por lo que pueden comenzar en partes del cuerpo sin músculo estriado, como el tracto urogenital. Generalmente, los perros afectados son jóvenes de hasta dos años y las masas neoplásicas parecen un racimo de uvas. El objetivo del presente informe fue describir un caso de rabdomiosarcoma botrioide en un perro American Pittbull Terrier de 16 meses que presentaba una masa en el interior de la vesicula urinaria, posteriormente diagnosticada mediante examen histopatológico e inmunohistoquímico. La masa era multilobulada, firme, de color rosado a rojo con áreas multifocales de necrosis y estaba adherida a la mucosa de la region más craneal de la vejiga urinaria, emitiendo ramas diseminadas hacia el trígono vesical. Microscópicamente, la neoplasia está formada por dos poblaciónes celulares intercaladas con una matriz mixoide, una compuesta por células pequeñas y redondas, con escaso citoplasma eosinofílico y núcleo basófilo hipercoloreado y la otra por células alargadas, con citoplasma eosinofílico y núcleo paracentral, ambas poblaciónes celulares presentaban pleomorfismo moderado y 2 cifras de mitosis por campo (400 x). Se observó un aumento de la densidad celular debajo del epitelio de la vejiga. La combinación de exámenes complementarios fue concluyente para el diagnóstico de la neoplasia.O rabdomiossarcoma botrióide é uma variante do rabdomiossarcoma embrionário e tem origem nas células musculares estriadas, ou precursores destas células, por isso podem se iniciar em partes do corpo com ausência de músculo estriado, como o trato urogenital. Geralmente, os cães acometidos são jovens até dois anos e as massas neoplásicas têm aspecto de cacho de uva. O objetivo do presente relato foi descrever um caso de rabdomiossarcoma botrióide em um cão, American Pittbull Terrier, de 16 meses que apresentou uma massa no interior da vesícula urinária, posteriormente diagnosticada através de exame histopatológico e imunoistoquímico. A massa era multilobulada, firme, rósea a vermelha com áreas multifocais de necrose e estava aderida na mucosa da região mais cranial da vesícula urinária emitindo ramificações disseminadas em direção ao trígono vesical. Microscopicamente, a neoplasia é constituída por duas populações celulares entremeadas a uma matriz mixóide, uma composta por células pequenas e redondas, com citoplasma escasso e núcleo basofílico hipercorado e a outra por células alongadas, com citoplasma eosinofílico e núcleo paracentral, ambas as populações celulares possuíam pleomorfismo moderado e 2 figuras de mitose por campo (400 x). Densidade celular aumentada foi observada abaixo do epitélio vesical. A combinação de exames complementares foi conclusiva para o diagnóstico da neoplasia.Research, Society and Development2021-05-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1488810.33448/rsd-v10i5.14888Research, Society and Development; Vol. 10 No. 5; e43210514888Research, Society and Development; Vol. 10 Núm. 5; e43210514888Research, Society and Development; v. 10 n. 5; e432105148882525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/14888/13567Copyright (c) 2021 Melissa Cristina Müller; Ana Catarina Luscher Albinati; Durval Baraúna Júnior; Cássia Regina Oliveira Santos; Eliane Feitosa Ferreira; Wasley Carlos Gonçalves de Matoshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMüller, Melissa CristinaAlbinati, Ana Catarina Luscher Baraúna Júnior, Durval Santos, Cássia Regina Oliveira Ferreira, Eliane Feitosa Matos, Wasley Carlos Gonçalves de 2021-05-17T18:20:49Zoai:ojs.pkp.sfu.ca:article/14888Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:35:51.522285Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Rhabdomyosarcoma in the urinary bladder of an American Pitbull Terrier Rabdomiosarcoma botrioide en la vejiga urinaria de un American Pittbull Terrier Rabdomiossarcoma botrióide na vesícula urinária de um American Pitbull Terrier |
title |
Rhabdomyosarcoma in the urinary bladder of an American Pitbull Terrier |
spellingShingle |
Rhabdomyosarcoma in the urinary bladder of an American Pitbull Terrier Müller, Melissa Cristina Perro Neoplasma Músculo estriado Sistema urinario. Dog Neoplasm Striated muscle Urinary system. Cão Neoplasia Músculo estriado Sistema urinário. |
title_short |
Rhabdomyosarcoma in the urinary bladder of an American Pitbull Terrier |
title_full |
Rhabdomyosarcoma in the urinary bladder of an American Pitbull Terrier |
title_fullStr |
Rhabdomyosarcoma in the urinary bladder of an American Pitbull Terrier |
title_full_unstemmed |
Rhabdomyosarcoma in the urinary bladder of an American Pitbull Terrier |
title_sort |
Rhabdomyosarcoma in the urinary bladder of an American Pitbull Terrier |
author |
Müller, Melissa Cristina |
author_facet |
Müller, Melissa Cristina Albinati, Ana Catarina Luscher Baraúna Júnior, Durval Santos, Cássia Regina Oliveira Ferreira, Eliane Feitosa Matos, Wasley Carlos Gonçalves de |
author_role |
author |
author2 |
Albinati, Ana Catarina Luscher Baraúna Júnior, Durval Santos, Cássia Regina Oliveira Ferreira, Eliane Feitosa Matos, Wasley Carlos Gonçalves de |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Müller, Melissa Cristina Albinati, Ana Catarina Luscher Baraúna Júnior, Durval Santos, Cássia Regina Oliveira Ferreira, Eliane Feitosa Matos, Wasley Carlos Gonçalves de |
dc.subject.por.fl_str_mv |
Perro Neoplasma Músculo estriado Sistema urinario. Dog Neoplasm Striated muscle Urinary system. Cão Neoplasia Músculo estriado Sistema urinário. |
topic |
Perro Neoplasma Músculo estriado Sistema urinario. Dog Neoplasm Striated muscle Urinary system. Cão Neoplasia Músculo estriado Sistema urinário. |
description |
Botryoid rhabdomyosarcoma is a variant of embryonic rhabdomyosarcoma and originates in striated muscle cells, or precursors of these cells, so they can start in parts of the body with the absence of striated muscle, such as the urogenital tract. Ser, the dogs affected are young up to two years old and the neoplastic masses look like a bunch of grapes. The objective of the present report was described as a case of botryoid rhabdomyosarcoma in a 16-month-old American Pittbull Terrier dog that presented a mass inside the urinary bladder, later diagnosed through histopathological and immunohistochemical examination. The mass was multilobulated, firm, pinkish to red with multifocal areas of necrosis and was adhered to the mucosa of the most cranial region of the urinary vesicle, emitting disseminated branches towards the bladder triangle. Microscopically, a neoplasm is discovered by two cell populations interspersed with a myxoid matrix, one composed of small, round cells, with scarce cytoplasm and hypercolored basophilic nucleus and the other by elongated cells, with eosinophilic and paracentral cytoplasm, both as having moderate and pleomorphism 2 mitosis figures per field (400 x). Increased cell density was observed below the bladder epithelium. A combination of complementary tests was conclusive for the diagnosis of neoplasia. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-05-12 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/14888 10.33448/rsd-v10i5.14888 |
url |
https://rsdjournal.org/index.php/rsd/article/view/14888 |
identifier_str_mv |
10.33448/rsd-v10i5.14888 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/14888/13567 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 5; e43210514888 Research, Society and Development; Vol. 10 Núm. 5; e43210514888 Research, Society and Development; v. 10 n. 5; e43210514888 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052806697320448 |