Repercussions of microplastics and nanoplastics on the gastrointestinal, circulatory and respiratory systems: A new potential for exposure
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/44992 |
Resumo: | Objective: Understand the forms of contamination and the consequences of microplastics and nanoplastics for the gastrointestinal, respiratory and cardiovascular systems. Methods: Integrative review using the Pubmed, SciELO, LILACS and Cochrane database platforms. The research was carried out using the search strategy: (“human health”) AND (“cell interaction”) OR (“microplastics”). A total of 489 articles were found. After applying the inclusion and exclusion criteria, 25 articles were selected, with 20 articles being removed after the initial analysis. This totaled 5 articles for full analysis. Results: Extensive damage from plastic particles to human health is evident. In the gastrointestinal system, increased local inflammation causes barrier dysfunction and reduced digestion of certain macromolecules. In the respiratory system, the reduction in mucociliary clearance leads to an increase in pathogens and a retention of debris, coming from external air, in the lung. In the cardiovascular system, changes in heart rate, as well as an increased risk of thrombosis are findings due to the presence of MPs and NPs. Conclusion: An integrated view of the damage caused by MPs and NPs and their interactions with human cells is concluded, but there is still no great evidence that allows us to assess the full extent of the damage. |
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Repercussions of microplastics and nanoplastics on the gastrointestinal, circulatory and respiratory systems: A new potential for exposure Repercusiones de los microplásticos y nanoplásticos en los sistemas gastrointestinal, circulatorio y respiratorio: Un nuevo potencial de exposición Repercussões dos microplásticos e nanoplásticos nos sistemas gastrointestinal, circulatório e respiratório: Um novo potencial de exposição MicroplásticoNanoplásticoDano celularRespiratórioCardiovascular.MicroplásticoNanoplásticoDano celularRespiratorioCardiovascular. MicroplasticNanoplasticCell damageRespiratoryCardiovascular. Objective: Understand the forms of contamination and the consequences of microplastics and nanoplastics for the gastrointestinal, respiratory and cardiovascular systems. Methods: Integrative review using the Pubmed, SciELO, LILACS and Cochrane database platforms. The research was carried out using the search strategy: (“human health”) AND (“cell interaction”) OR (“microplastics”). A total of 489 articles were found. After applying the inclusion and exclusion criteria, 25 articles were selected, with 20 articles being removed after the initial analysis. This totaled 5 articles for full analysis. Results: Extensive damage from plastic particles to human health is evident. In the gastrointestinal system, increased local inflammation causes barrier dysfunction and reduced digestion of certain macromolecules. In the respiratory system, the reduction in mucociliary clearance leads to an increase in pathogens and a retention of debris, coming from external air, in the lung. In the cardiovascular system, changes in heart rate, as well as an increased risk of thrombosis are findings due to the presence of MPs and NPs. Conclusion: An integrated view of the damage caused by MPs and NPs and their interactions with human cells is concluded, but there is still no great evidence that allows us to assess the full extent of the damage. Objetivo: Comprender las formas de contaminación y las consecuencias de los microplásticos y nanoplásticos para el sistema gastrointestinal, respiratorio y cardiovascular. Métodos: Revisión integradora utilizando las plataformas de bases de datos Pubmed, SciELO, LILACS y Cochrane. La investigación se realizó mediante la estrategia de búsqueda: (“salud humana”) Y (“interacción celular”) O (“microplásticos”). Se encontraron un total de 489 artículos. Luego de aplicar los criterios de inclusión y exclusión, se seleccionaron 25 artículos, siendo eliminados 20 artículos luego del análisis inicial. Esto totalizó 5 artículos para un análisis completo. Resultados: Es evidente el gran daño que las partículas de plástico causan a la salud humana. En el sistema gastrointestinal, el aumento de la inflamación local provoca una disfunción de la barrera y una reducción de la digestión de determinadas macromoléculas. En el sistema respiratorio, la reducción del aclaramiento mucociliar provoca un aumento de patógenos y una retención de desechos procedentes del aire exterior en el pulmón. En el sistema cardiovascular, los cambios en la frecuencia cardíaca, así como un mayor riesgo de trombosis, son hallazgos debido a la presencia de MP y NP. Conclusión: Se concluye una visión integrada del daño causado por MPs y NPs y sus interacciones con las células humanas, pero aún no existe gran evidencia que permita evaluar el alcance total del daño. Objetivo: Compreender as formas de contaminação e as consequências dos microplásticos (MPs) e nanoplásticos (NPs) para os sistemas gastrointestinal, respiratório e cardiovascular. Métodos: Revisão integrativa através das plataformas de base de dados Pubmed, SciELO, LILACS e Cochrane. A pesquisa foi feita através da estratégia de pesquisa: (“human health”) AND (“cell interaction”) OR (“microplastics”). Foram encontrados um total de 489 artigos. Após a aplicação dos critérios de inclusão e exclusão, foram selecionados 25 artigos, sendo removidos 20 artigos após a análise inicial. Isso totalizou 5 artigos para análise completa. Resultados: Evidencia-se extensos danos das partículas plásticas na saúde humana. No sistema gastrointestinal, o aumento da inflamação local causa disfunção da barreira e redução da digestão de determinadas macromoléculas. No sistema respiratório, a redução da depuração mucociliar corrobora para um acréscimo de patógenos e uma permanência de detritos, provenientes do ar externo, no pulmão. No sistema cardiovascular, alterações da frequência cardíaca, bem como o aumento do risco de trombose são achados da presença dos MPs e NPs. Considerações finais: Conclui-se uma visão integrada dos danos promovidos pelos MPs e NPs e suas interações com as células humanas, porém ainda não existem grandes evidências que permitam avaliar a extensão total dos danos.Research, Society and Development2024-02-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4499210.33448/rsd-v13i2.44992Research, Society and Development; Vol. 13 No. 2; e4013244992Research, Society and Development; Vol. 13 Núm. 2; e4013244992Research, Society and Development; v. 13 n. 2; e40132449922525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/44992/35919Copyright (c) 2024 Ruan Matheus Alves da Silva; Carla Manuella Campelo Guerra Queiroz Campos; Arthur Barbosa Barbosa; Caio Pinheiro Ferreira Tenório; Daniele Schiavi; Gabriela Ximenes de Menezes; Helena Pôrto de Pôrto; Pedro Rafael Salerno; Suziane Menezes Rodrigues; Yasmin Duarte Duartehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Ruan Matheus Alves da Campos, Carla Manuella Campelo Guerra Queiroz Mota, Arthur BarbosaTenório, Caio Pinheiro Ferreira Schiavi, Daniele Menezes, Gabriela Ximenes de Assis, Helena Pôrto de Salerno, Pedro Rafael Rodrigues, Suziane Menezes Costa, Yasmin Duarte 2024-03-04T09:47:20Zoai:ojs.pkp.sfu.ca:article/44992Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-03-04T09:47:20Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Repercussions of microplastics and nanoplastics on the gastrointestinal, circulatory and respiratory systems: A new potential for exposure Repercusiones de los microplásticos y nanoplásticos en los sistemas gastrointestinal, circulatorio y respiratorio: Un nuevo potencial de exposición Repercussões dos microplásticos e nanoplásticos nos sistemas gastrointestinal, circulatório e respiratório: Um novo potencial de exposição |
title |
Repercussions of microplastics and nanoplastics on the gastrointestinal, circulatory and respiratory systems: A new potential for exposure |
spellingShingle |
Repercussions of microplastics and nanoplastics on the gastrointestinal, circulatory and respiratory systems: A new potential for exposure Silva, Ruan Matheus Alves da Microplástico Nanoplástico Dano celular Respiratório Cardiovascular. Microplástico Nanoplástico Dano celular Respiratorio Cardiovascular. Microplastic Nanoplastic Cell damage Respiratory Cardiovascular. |
title_short |
Repercussions of microplastics and nanoplastics on the gastrointestinal, circulatory and respiratory systems: A new potential for exposure |
title_full |
Repercussions of microplastics and nanoplastics on the gastrointestinal, circulatory and respiratory systems: A new potential for exposure |
title_fullStr |
Repercussions of microplastics and nanoplastics on the gastrointestinal, circulatory and respiratory systems: A new potential for exposure |
title_full_unstemmed |
Repercussions of microplastics and nanoplastics on the gastrointestinal, circulatory and respiratory systems: A new potential for exposure |
title_sort |
Repercussions of microplastics and nanoplastics on the gastrointestinal, circulatory and respiratory systems: A new potential for exposure |
author |
Silva, Ruan Matheus Alves da |
author_facet |
Silva, Ruan Matheus Alves da Campos, Carla Manuella Campelo Guerra Queiroz Mota, Arthur Barbosa Tenório, Caio Pinheiro Ferreira Schiavi, Daniele Menezes, Gabriela Ximenes de Assis, Helena Pôrto de Salerno, Pedro Rafael Rodrigues, Suziane Menezes Costa, Yasmin Duarte |
author_role |
author |
author2 |
Campos, Carla Manuella Campelo Guerra Queiroz Mota, Arthur Barbosa Tenório, Caio Pinheiro Ferreira Schiavi, Daniele Menezes, Gabriela Ximenes de Assis, Helena Pôrto de Salerno, Pedro Rafael Rodrigues, Suziane Menezes Costa, Yasmin Duarte |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Silva, Ruan Matheus Alves da Campos, Carla Manuella Campelo Guerra Queiroz Mota, Arthur Barbosa Tenório, Caio Pinheiro Ferreira Schiavi, Daniele Menezes, Gabriela Ximenes de Assis, Helena Pôrto de Salerno, Pedro Rafael Rodrigues, Suziane Menezes Costa, Yasmin Duarte |
dc.subject.por.fl_str_mv |
Microplástico Nanoplástico Dano celular Respiratório Cardiovascular. Microplástico Nanoplástico Dano celular Respiratorio Cardiovascular. Microplastic Nanoplastic Cell damage Respiratory Cardiovascular. |
topic |
Microplástico Nanoplástico Dano celular Respiratório Cardiovascular. Microplástico Nanoplástico Dano celular Respiratorio Cardiovascular. Microplastic Nanoplastic Cell damage Respiratory Cardiovascular. |
description |
Objective: Understand the forms of contamination and the consequences of microplastics and nanoplastics for the gastrointestinal, respiratory and cardiovascular systems. Methods: Integrative review using the Pubmed, SciELO, LILACS and Cochrane database platforms. The research was carried out using the search strategy: (“human health”) AND (“cell interaction”) OR (“microplastics”). A total of 489 articles were found. After applying the inclusion and exclusion criteria, 25 articles were selected, with 20 articles being removed after the initial analysis. This totaled 5 articles for full analysis. Results: Extensive damage from plastic particles to human health is evident. In the gastrointestinal system, increased local inflammation causes barrier dysfunction and reduced digestion of certain macromolecules. In the respiratory system, the reduction in mucociliary clearance leads to an increase in pathogens and a retention of debris, coming from external air, in the lung. In the cardiovascular system, changes in heart rate, as well as an increased risk of thrombosis are findings due to the presence of MPs and NPs. Conclusion: An integrated view of the damage caused by MPs and NPs and their interactions with human cells is concluded, but there is still no great evidence that allows us to assess the full extent of the damage. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-02-11 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/44992 10.33448/rsd-v13i2.44992 |
url |
https://rsdjournal.org/index.php/rsd/article/view/44992 |
identifier_str_mv |
10.33448/rsd-v13i2.44992 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/44992/35919 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 13 No. 2; e4013244992 Research, Society and Development; Vol. 13 Núm. 2; e4013244992 Research, Society and Development; v. 13 n. 2; e4013244992 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052638081056768 |