Abnormal laboratory findings review in SARS-CoV-2 infection
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/28793 |
Resumo: | COVID-19 can trigger damage to the function and integrity of multiple cells, tissue or organs. In the progression of clinical manifestations, laboratory biomarkers can be used as predictors of prognosis to support in clinical conduction. This study aims to evidence an updated review of the literature of changes in biochemical and hematological laboratory tests of individuals with COVID-19 from articles prospected from the SciELO, LILACS and PubMed databases. Although in severe clinical spectrums, especially in patients admitted to intensive care unit, tissue lesions are more intense and more evident laboratory changes, can be observed in general in patients infected with SARS-CoV-2 increased levels of transaminases, alkaline phosphatase, gamma glutamyl transferase, bilirubin, urea, creatinine, lactic dehydrogenases, amylase, lipase, troponins, NT-ProBNP, pro-BNP, as well as reduction of MCV and MCHC, lymphopenia, neutrophilia, eosinopenia, thrombocytopenia, and prolongation of PT and aPTT. |
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Abnormal laboratory findings review in SARS-CoV-2 infection Revisión de hallazgos anormales de laboratorio en la infección por SARS-CoV-2 Revisão sobre as alterações em exames laboratoriais na infecção pelo SARS-CoV-2 COVID-19SARS-CoV-2Laboratory testsHealth teaching.COVID-19SARS-CoV-2Exames laboratoriaisEnsino em saúde.COVID-19SARS-CoV-2Pruebas de laboratorioEnseñanza en la salud.COVID-19 can trigger damage to the function and integrity of multiple cells, tissue or organs. In the progression of clinical manifestations, laboratory biomarkers can be used as predictors of prognosis to support in clinical conduction. This study aims to evidence an updated review of the literature of changes in biochemical and hematological laboratory tests of individuals with COVID-19 from articles prospected from the SciELO, LILACS and PubMed databases. Although in severe clinical spectrums, especially in patients admitted to intensive care unit, tissue lesions are more intense and more evident laboratory changes, can be observed in general in patients infected with SARS-CoV-2 increased levels of transaminases, alkaline phosphatase, gamma glutamyl transferase, bilirubin, urea, creatinine, lactic dehydrogenases, amylase, lipase, troponins, NT-ProBNP, pro-BNP, as well as reduction of MCV and MCHC, lymphopenia, neutrophilia, eosinopenia, thrombocytopenia, and prolongation of PT and aPTT.COVID-19 puede desencadenar daños en la función y la integridad de múltiples células, tejidos y órganos. En la progresión de las manifestaciones clínicas, se pueden utilizar los biomarcadores de laboratorio como predictores de pronóstico para ayudar en la conducción clínica. Este estudio tiene como objetivo evidenciar una revisión actualizada de los cambios en las pruebas bioquímicas y hematológicas de laboratorio de individuos con COVID-19 a partir de artículos prospectados de las bases de datos SciELO, LILACS y PubMed. Aunque en espectros clínicos más graves, especialmente en pacientes ingresados en UCI, las lesiones tisulares son más intensas y las alteraciones de laboratorio más evidentes, se puede observar en general en pacientes infectados con SARS-CoV-2 aumento de los niveles de transaminasas, FA, GGT, bilirrubina, urea, creatinina, LDH, amilasa, lipasa, cTnI, NT-ProBNP y pro-BNP, así como reducción de los índices hematimétricos VM y CHCM, linfopenia, neutrofilia, eosinopenia, trombocitopenia y prolongación de TP y TTPA.A COVID-19 pode desencadear prejuízos na função e integridade de múltiplas células, tecidos e órgãos. Na progressão das manifestações clínicas, biomarcadores laboratoriais podem ser utilizados como preditores do prognóstico para auxílio na condução clínica. Este estudo tem como objetivo evidenciar uma revisão atualizada das alterações nos exames laboratoriais bioquímicos e hematológicos de indivíduos com COVID-19 a partir de artigos prospectados das bases SciELO, LILACS e PubMed. Embora em espectros clínicos mais graves, principalmente nos pacientes admitidos em UTI, as lesões teciduais sejam mais intensas e as alterações laboratoriais mais evidentes, podem ser observados de forma geral nos pacientes infectados pelo SARS-CoV-2 aumento dos níveis de transaminases, FA, GGT, bilirrubina, ureia, creatinina, LDH, amilase, lipase, cTnI, NT-ProBNP e pro-BNP, bem como redução dos índices hematimétricos VCM e CHCM, linfopenia, neutrofilia, eosinopenia, trombocitopenia e prolongamento do TP e TTPA.Research, Society and Development2022-04-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2879310.33448/rsd-v11i5.28793Research, Society and Development; Vol. 11 No. 5; e59611528793Research, Society and Development; Vol. 11 Núm. 5; e59611528793Research, Society and Development; v. 11 n. 5; e596115287932525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/28793/24896Copyright (c) 2022 Marcus Vinicius Alves Lima; Polliana Silva Rodrigues; João Otávio Ferreira Pereira; Caroline Felix da Silva Mota; Monica Nascimento Bittencourt; Winnie Revilane de Melo Marques; Cristina de Jesus Gomes; Luciana Machado de Castro; Idalina Sá de Oliveira; Elinete de Jesus Bispo; Ana Kerlei Afonso Silva; Laíza de Oliveira Almeida; Rafael de Carvalho Barreiros; Tatiane dos Santos Silva; Luciele Cristina Lange; Afrânio Ferreira Evangelistahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessLima, Marcus Vinicius Alves Rodrigues, Polliana SilvaPereira, João Otávio Ferreira Mota, Caroline Felix da Silva Bittencourt, Monica Nascimento Marques, Winnie Revilane de Melo Gomes, Cristina de Jesus Castro, Luciana Machado de Oliveira, Idalina Sá de Bispo, Elinete de Jesus Silva, Ana Kerlei Afonso Almeida, Laíza de Oliveira Barreiros, Rafael de Carvalho Silva, Tatiane dos Santos Lange, Luciele Cristina Evangelista, Afrânio Ferreira 2022-04-17T18:18:56Zoai:ojs.pkp.sfu.ca:article/28793Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:46:04.233914Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Abnormal laboratory findings review in SARS-CoV-2 infection Revisión de hallazgos anormales de laboratorio en la infección por SARS-CoV-2 Revisão sobre as alterações em exames laboratoriais na infecção pelo SARS-CoV-2 |
| title |
Abnormal laboratory findings review in SARS-CoV-2 infection |
| spellingShingle |
Abnormal laboratory findings review in SARS-CoV-2 infection Lima, Marcus Vinicius Alves COVID-19 SARS-CoV-2 Laboratory tests Health teaching. COVID-19 SARS-CoV-2 Exames laboratoriais Ensino em saúde. COVID-19 SARS-CoV-2 Pruebas de laboratorio Enseñanza en la salud. |
| title_short |
Abnormal laboratory findings review in SARS-CoV-2 infection |
| title_full |
Abnormal laboratory findings review in SARS-CoV-2 infection |
| title_fullStr |
Abnormal laboratory findings review in SARS-CoV-2 infection |
| title_full_unstemmed |
Abnormal laboratory findings review in SARS-CoV-2 infection |
| title_sort |
Abnormal laboratory findings review in SARS-CoV-2 infection |
| author |
Lima, Marcus Vinicius Alves |
| author_facet |
Lima, Marcus Vinicius Alves Rodrigues, Polliana Silva Pereira, João Otávio Ferreira Mota, Caroline Felix da Silva Bittencourt, Monica Nascimento Marques, Winnie Revilane de Melo Gomes, Cristina de Jesus Castro, Luciana Machado de Oliveira, Idalina Sá de Bispo, Elinete de Jesus Silva, Ana Kerlei Afonso Almeida, Laíza de Oliveira Barreiros, Rafael de Carvalho Silva, Tatiane dos Santos Lange, Luciele Cristina Evangelista, Afrânio Ferreira |
| author_role |
author |
| author2 |
Rodrigues, Polliana Silva Pereira, João Otávio Ferreira Mota, Caroline Felix da Silva Bittencourt, Monica Nascimento Marques, Winnie Revilane de Melo Gomes, Cristina de Jesus Castro, Luciana Machado de Oliveira, Idalina Sá de Bispo, Elinete de Jesus Silva, Ana Kerlei Afonso Almeida, Laíza de Oliveira Barreiros, Rafael de Carvalho Silva, Tatiane dos Santos Lange, Luciele Cristina Evangelista, Afrânio Ferreira |
| author2_role |
author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Lima, Marcus Vinicius Alves Rodrigues, Polliana Silva Pereira, João Otávio Ferreira Mota, Caroline Felix da Silva Bittencourt, Monica Nascimento Marques, Winnie Revilane de Melo Gomes, Cristina de Jesus Castro, Luciana Machado de Oliveira, Idalina Sá de Bispo, Elinete de Jesus Silva, Ana Kerlei Afonso Almeida, Laíza de Oliveira Barreiros, Rafael de Carvalho Silva, Tatiane dos Santos Lange, Luciele Cristina Evangelista, Afrânio Ferreira |
| dc.subject.por.fl_str_mv |
COVID-19 SARS-CoV-2 Laboratory tests Health teaching. COVID-19 SARS-CoV-2 Exames laboratoriais Ensino em saúde. COVID-19 SARS-CoV-2 Pruebas de laboratorio Enseñanza en la salud. |
| topic |
COVID-19 SARS-CoV-2 Laboratory tests Health teaching. COVID-19 SARS-CoV-2 Exames laboratoriais Ensino em saúde. COVID-19 SARS-CoV-2 Pruebas de laboratorio Enseñanza en la salud. |
| description |
COVID-19 can trigger damage to the function and integrity of multiple cells, tissue or organs. In the progression of clinical manifestations, laboratory biomarkers can be used as predictors of prognosis to support in clinical conduction. This study aims to evidence an updated review of the literature of changes in biochemical and hematological laboratory tests of individuals with COVID-19 from articles prospected from the SciELO, LILACS and PubMed databases. Although in severe clinical spectrums, especially in patients admitted to intensive care unit, tissue lesions are more intense and more evident laboratory changes, can be observed in general in patients infected with SARS-CoV-2 increased levels of transaminases, alkaline phosphatase, gamma glutamyl transferase, bilirubin, urea, creatinine, lactic dehydrogenases, amylase, lipase, troponins, NT-ProBNP, pro-BNP, as well as reduction of MCV and MCHC, lymphopenia, neutrophilia, eosinopenia, thrombocytopenia, and prolongation of PT and aPTT. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-04-17 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/28793 10.33448/rsd-v11i5.28793 |
| url |
https://rsdjournal.org/index.php/rsd/article/view/28793 |
| identifier_str_mv |
10.33448/rsd-v11i5.28793 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
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https://rsdjournal.org/index.php/rsd/article/view/28793/24896 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Research, Society and Development |
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Research, Society and Development |
| dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 5; e59611528793 Research, Society and Development; Vol. 11 Núm. 5; e59611528793 Research, Society and Development; v. 11 n. 5; e59611528793 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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1797052811773476864 |