Changes in taste resulting from conventional chemotherapy

Detalhes bibliográficos
Autor(a) principal: Silva, Eduardo Henrique dos Santos
Data de Publicação: 2021
Outros Autores: Aguiar, Yuri Lopes de, Amaral, Polyana Argolo Souza, Pereira, Lara Correia
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/22467
Resumo: Cancer is linked to the disordered increase of cells, has the ability to invade neighboring tissues in the place of origin and/or install itself in distant organs via the bloodstream. Antineoplastic treatment can generate side effects in the oral mucosa, being evident through the appearance of oral mucositis. We can also observe changes in taste, such as: hypogeusia, dysgeusia, ageusia and hypergeusia. The present work aims to review the literature on taste alterations caused by 5-fluorouracil (5-FU), leucovorine, oxaliplatin, gemcitabine, capecitabine, cisplatin, cyclophosphamide, doxorubicin, irinotecan and methotrexate, being conventional antineoplastic drugs. This study was carried out by collecting data from 2009 to 2021, from scientific literature in the PubMed, Lilacs, Cochrane and Scielo databases in English and Spanish, using the key words Antineoplastics; Distorted taste; Dysgeusia; Stomatitis; Oral cavity; together with the Boolean operators “and” and “or”, in order to combine the aforementioned descriptors. Given the above, conventional chemotherapy drugs affect taste cells and biochemical processes related to their cell renewal, generating changes in taste such as hypogeusia, dysgeusia, ageusia and hypergeusia.
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spelling Changes in taste resulting from conventional chemotherapyCambios en el gusto resultantes de la quimioterapia convencionalAlterações no paladar advindos de quimioterapia convencional AntineoplásticosGusto distorsionadoDisgeusiaEstomatitaCavidad oral.AntineoplásicosPaladar distorcidoDisgeusiaEstomatiteCavidade oral.AntineoplasticsDistorted tasteDysgeusiaStomatitisOral cavity.Cancer is linked to the disordered increase of cells, has the ability to invade neighboring tissues in the place of origin and/or install itself in distant organs via the bloodstream. Antineoplastic treatment can generate side effects in the oral mucosa, being evident through the appearance of oral mucositis. We can also observe changes in taste, such as: hypogeusia, dysgeusia, ageusia and hypergeusia. The present work aims to review the literature on taste alterations caused by 5-fluorouracil (5-FU), leucovorine, oxaliplatin, gemcitabine, capecitabine, cisplatin, cyclophosphamide, doxorubicin, irinotecan and methotrexate, being conventional antineoplastic drugs. This study was carried out by collecting data from 2009 to 2021, from scientific literature in the PubMed, Lilacs, Cochrane and Scielo databases in English and Spanish, using the key words Antineoplastics; Distorted taste; Dysgeusia; Stomatitis; Oral cavity; together with the Boolean operators “and” and “or”, in order to combine the aforementioned descriptors. Given the above, conventional chemotherapy drugs affect taste cells and biochemical processes related to their cell renewal, generating changes in taste such as hypogeusia, dysgeusia, ageusia and hypergeusia.El cáncer está relacionado con el aumento desordenado de células, tiene la capacidad de invadir los tejidos vecinos en el lugar de origen y / o instalarse en órganos distantes a través del torrente sanguíneo. El tratamiento antineoplásico puede generar efectos secundarios en la mucosa bucal, siendo evidentes por la aparición de mucositis bucal. También podemos observar cambios en el gusto, como: hipogeusia, disgeusia, ageusia e hipergeusia. El presente trabajo tiene como objetivo revisar la literatura sobre las alteraciones del gusto causadas por 5-fluorouracilo (5-FU), leucovorina, oxaliplatino, gemcitabina, capecitabina, cisplatino, ciclofosfamida, doxorrubicina, irinotecán y metotrexato, siendo fármacos antineoplásicos convencionales. Este estudio se llevó a cabo mediante la recolección de datos de 2009 a 2021, de la literatura científica en las bases de datos PubMed, Lilacs, Cochrane y Scielo en inglés y español, utilizando las palabras clave Antineoplásticos; Sabor distorsionado; Disgeusia; Estomatitis; Cavidad oral; junto con los operadores booleanos “y” y “o”, con el fin de combinar los descriptores antes mencionados. Dado lo anterior, los fármacos quimioterápicos convencionales afectan las células gustativas y los procesos bioquímicos relacionados con su renovación celular, generando cambios en el gusto como hipogeusia, disgeusia, ageusia e hipergeusia.O câncer está ligado ao aumento desordenado de células, possui a capacidade de invadir tecidos vizinhos no local de origem e/ou instalar-se em órgãos distantes via corrente sanguínea. O tratamento antineoplásico pode gerar efeitos colaterais, na mucosa oral, ficando evidente através do surgimento da mucosite oral. Também podemos observar alterações no paladar, como: hipogeusia, disgeusia, ageusia e hipergeusia. O presente trabalho visa revisar a literatura acerca das alterações do paladar provocadas por 5-fluoruracila (5-FU), leucovorine, oxaliplatina, gencitabine, capecitabine, cisplatina, ciclofosfamida, doxorubicina, irinotecan e metotrexato, sendo medicamentos antineoplásicos convencionais. Este estudo foi realizado através do levantamento de dados no período de 2009 até 2021, a partir da literatura científica na base de dados PubMed, Lilacs, Cochrane e Scielo em língua inglesa e espanhola, valendo-se das palavras chaves Antinéoplasicos; Paladar Distorcido; Disgeusia; Estomatite; Cavidade Oral; juntamente com os operadorer booleanos “and” e “or”, de forma a combinar os descritores citados.  Diante do exposto, os fármacos quimioterápicos convencionais afetam as células gustativas e os processos bioquímicos referentes a sua renovação celular, gerando alterações no paladar como hipogeusia, disgeusia, ageusia e hipergeusia.Research, Society and Development2021-11-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2246710.33448/rsd-v10i14.22467Research, Society and Development; Vol. 10 No. 14; e589101422467Research, Society and Development; Vol. 10 Núm. 14; e589101422467Research, Society and Development; v. 10 n. 14; e5891014224672525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/22467/20286Copyright (c) 2021 Eduardo Henrique dos Santos Silva; Yuri Lopes de Aguiar; Polyana Argolo Souza Amaral; Lara Correia Pereirahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Eduardo Henrique dos Santos Aguiar, Yuri Lopes de Amaral, Polyana Argolo Souza Pereira, Lara Correia 2021-12-04T11:48:39Zoai:ojs.pkp.sfu.ca:article/22467Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:41:37.752254Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Changes in taste resulting from conventional chemotherapy
Cambios en el gusto resultantes de la quimioterapia convencional
Alterações no paladar advindos de quimioterapia convencional
title Changes in taste resulting from conventional chemotherapy
spellingShingle Changes in taste resulting from conventional chemotherapy
Silva, Eduardo Henrique dos Santos
Antineoplásticos
Gusto distorsionado
Disgeusia
Estomatita
Cavidad oral.
Antineoplásicos
Paladar distorcido
Disgeusia
Estomatite
Cavidade oral.
Antineoplastics
Distorted taste
Dysgeusia
Stomatitis
Oral cavity.
title_short Changes in taste resulting from conventional chemotherapy
title_full Changes in taste resulting from conventional chemotherapy
title_fullStr Changes in taste resulting from conventional chemotherapy
title_full_unstemmed Changes in taste resulting from conventional chemotherapy
title_sort Changes in taste resulting from conventional chemotherapy
author Silva, Eduardo Henrique dos Santos
author_facet Silva, Eduardo Henrique dos Santos
Aguiar, Yuri Lopes de
Amaral, Polyana Argolo Souza
Pereira, Lara Correia
author_role author
author2 Aguiar, Yuri Lopes de
Amaral, Polyana Argolo Souza
Pereira, Lara Correia
author2_role author
author
author
dc.contributor.author.fl_str_mv Silva, Eduardo Henrique dos Santos
Aguiar, Yuri Lopes de
Amaral, Polyana Argolo Souza
Pereira, Lara Correia
dc.subject.por.fl_str_mv Antineoplásticos
Gusto distorsionado
Disgeusia
Estomatita
Cavidad oral.
Antineoplásicos
Paladar distorcido
Disgeusia
Estomatite
Cavidade oral.
Antineoplastics
Distorted taste
Dysgeusia
Stomatitis
Oral cavity.
topic Antineoplásticos
Gusto distorsionado
Disgeusia
Estomatita
Cavidad oral.
Antineoplásicos
Paladar distorcido
Disgeusia
Estomatite
Cavidade oral.
Antineoplastics
Distorted taste
Dysgeusia
Stomatitis
Oral cavity.
description Cancer is linked to the disordered increase of cells, has the ability to invade neighboring tissues in the place of origin and/or install itself in distant organs via the bloodstream. Antineoplastic treatment can generate side effects in the oral mucosa, being evident through the appearance of oral mucositis. We can also observe changes in taste, such as: hypogeusia, dysgeusia, ageusia and hypergeusia. The present work aims to review the literature on taste alterations caused by 5-fluorouracil (5-FU), leucovorine, oxaliplatin, gemcitabine, capecitabine, cisplatin, cyclophosphamide, doxorubicin, irinotecan and methotrexate, being conventional antineoplastic drugs. This study was carried out by collecting data from 2009 to 2021, from scientific literature in the PubMed, Lilacs, Cochrane and Scielo databases in English and Spanish, using the key words Antineoplastics; Distorted taste; Dysgeusia; Stomatitis; Oral cavity; together with the Boolean operators “and” and “or”, in order to combine the aforementioned descriptors. Given the above, conventional chemotherapy drugs affect taste cells and biochemical processes related to their cell renewal, generating changes in taste such as hypogeusia, dysgeusia, ageusia and hypergeusia.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-14
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/22467
10.33448/rsd-v10i14.22467
url https://rsdjournal.org/index.php/rsd/article/view/22467
identifier_str_mv 10.33448/rsd-v10i14.22467
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/22467/20286
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 14; e589101422467
Research, Society and Development; Vol. 10 Núm. 14; e589101422467
Research, Society and Development; v. 10 n. 14; e589101422467
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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