Pseudoresistant hypertension caused by inappropriate drug regimen

• Autor(a) principal: Nascimento , Victor Barbosa
• Data de Publicação: 2022
• Outros Autores: Silva, Rosileide Zeferino da, Carvalho, Janaina Fraga de, Leopardi-Gonçalves, Maria das Graças, Oliveira-Filho, Alfredo Dias de, Neves, Sabrina Joany Felizardo
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/32004
• topic: Hipertensión seudoresistente; Prescripción; Farmacoterapia.; Hipertensão resistente; Prescrição; Terapia medicamentosa.; Resistant hypertension; Prescription; Drug therapy.

Background: The diagnosis of resistant hypertension (RHTN) requires the identification and exclusion of pseudoresistance cases, which is due to poor blood pressure measurement technique, white coat hypertension, low medication adherence, and/or inappropriate drug regimen. Aim: This study aimed to assess the prevalence of pseudoresistant hypertension (pRHTN) caused by Inappropriate Drug Regimen (IDR). Methods: A cross-sectional study was carried out with patients seen in primary care in Maceió, Brazil, between December 2013 and February 2014. Patients diagnosed with hypertension and undergoing drug treatment were included. Patients were assessed for medication use, analysis of the antihypertensive drug regimen, medication adherence, values ​​for Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP). Results: 183 patients were included in the study, of which 8 (4.3%) had RHTN and 12 (6.6%) had pRHTN. All patients with pRHTN had IDR. Also, 74.8% of patients with primary hypertension were exposed to IDR (p = 0.000). The most frequent type of IDR among patients with pRHTN was therapeutic inertia. Conclusion: Thus, we conclude that IDR is recurrent among patients with pRHTN and therapeutic inertia was the most frequent type of IDR.