Association between the use of female hormones and the thrombin generation: Cross-sectional analysis of the Longitudinal Study on Adult Health (ELSA-Brasil)

Detalhes bibliográficos
Autor(a) principal: Batista, Thaís Resende
Data de Publicação: 2021
Outros Autores: Barreto, Sandhi Maria, Silva, Ana Paula Ferreira, Oliveira Junior, Wander Valadares de, Maluf, Chams Bicalho, Ribeiro, Antônio Luiz Pinho, Carvalho, Maria das Graças, Figueiredo, Roberta Carvalho de, Rios, Danyelle Romana Alves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/17888
Resumo: Introduction: The thrombin generation assay (TGA) assesses the risk of developing thrombotic events. The aim of this study was to investigate the association between the use of oral contraceptives (OCs) and hormone therapy (HT) with the TGA and resistance to activated protein C (APC). Methods: Cross-sectional study with women from the Longitudinal Study of Adult Health (ELSA-Brasil). TGA was performed by the CAT method. Results: There was an association between all parameters of the TGA and the use of OCs and an association of lag time and peak time with the use of HT. Conclusion: The TGA allows us to assess the hypercoagulability status and may be useful in the management of female hormones users.
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spelling Association between the use of female hormones and the thrombin generation: Cross-sectional analysis of the Longitudinal Study on Adult Health (ELSA-Brasil)Asociación entre uso de anticonceptivos orales y terapia hormonal y generación de trombina: Análisis transversal del Estudio Longitudinal de Salud del Adulto (ELSA-Brasil)Associação entre o uso de contraceptivos orais e terapia hormonal e a geração de trombina: Análise transversal do Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil)Anticoncepcionais oraisTerapia de Reposição HormonalTestes de coagulação sanguínea.Contraceptives, OralHormone Replacement TherapyBlood coagulation tests.Anticonceptivos OralesTerapia de Reemplazo de HormonasPruebas de coagulación sanguínea.Introduction: The thrombin generation assay (TGA) assesses the risk of developing thrombotic events. The aim of this study was to investigate the association between the use of oral contraceptives (OCs) and hormone therapy (HT) with the TGA and resistance to activated protein C (APC). Methods: Cross-sectional study with women from the Longitudinal Study of Adult Health (ELSA-Brasil). TGA was performed by the CAT method. Results: There was an association between all parameters of the TGA and the use of OCs and an association of lag time and peak time with the use of HT. Conclusion: The TGA allows us to assess the hypercoagulability status and may be useful in the management of female hormones users.Introducción: La prueba de generación de trombina (TGT) evalúa el riesgo de desarrollar eventos trombóticos. El objetivo de este estudio fue investigar la asociación entre el uso de anticonceptivos orales (AO) y la terapia hormonal (TH) con TGT y la resistencia a la proteína C activada (CaP). Métodos: Estudio transversal con mujeres del Estudio Longitudinal de Salud del Adulto (ELSA-Brasil). La TGT se realizó mediante el método CAT. Resultados: Hubo asociación entre todos los parámetros TGT y el uso de CO y asociación de latencia y tiempo pico con el uso de TH. Conclusión: TGT permite la evaluación del estado de hipercoagulabilidad y puede ser útil en el manejo de mujeres usuarias de hormonas.Introdução: O teste de geração de trombina (TGT) avalia o risco de desenvolvimento de eventos trombóticos. O objetivo deste estudo foi investigar a associação entre o uso de contraceptivos orais (COs) e a terapia hormonal (TH) com a TGT e a resistência à proteína C ativada (PCa). Métodos: Estudo transversal com mulheres do Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil). A TGT foi realizada pelo método CAT. Resultados: Houve associação entre todos os parâmetros do TGT e o uso de COs e associação do tempo de latência e pico com o uso de TH. Conclusão: A TGT permite avaliar o estado de hipercoagulabilidade e pode ser útil no manejo de usuárias de hormônios femininos.Research, Society and Development2021-08-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1788810.33448/rsd-v10i9.17888Research, Society and Development; Vol. 10 No. 9; e12910917888Research, Society and Development; Vol. 10 Núm. 9; e12910917888Research, Society and Development; v. 10 n. 9; e129109178882525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/17888/16517Copyright (c) 2021 Thaís Resende Batista; Sandhi Maria Barreto; Ana Paula Ferreira Silva; Wander Valadares de Oliveira Junior; Chams Bicalho Maluf; Antônio Luiz Pinho Ribeiro; Maria das Graças Carvalho; Roberta Carvalho de Figueiredo; Danyelle Romana Alves Rioshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBatista, Thaís Resende Barreto, Sandhi Maria Silva, Ana Paula FerreiraOliveira Junior, Wander Valadares de Maluf, Chams Bicalho Ribeiro, Antônio Luiz Pinho Carvalho, Maria das Graças Figueiredo, Roberta Carvalho deRios, Danyelle Romana Alves2021-09-12T14:28:06Zoai:ojs.pkp.sfu.ca:article/17888Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:38:08.816159Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Association between the use of female hormones and the thrombin generation: Cross-sectional analysis of the Longitudinal Study on Adult Health (ELSA-Brasil)
Asociación entre uso de anticonceptivos orales y terapia hormonal y generación de trombina: Análisis transversal del Estudio Longitudinal de Salud del Adulto (ELSA-Brasil)
Associação entre o uso de contraceptivos orais e terapia hormonal e a geração de trombina: Análise transversal do Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil)
title Association between the use of female hormones and the thrombin generation: Cross-sectional analysis of the Longitudinal Study on Adult Health (ELSA-Brasil)
spellingShingle Association between the use of female hormones and the thrombin generation: Cross-sectional analysis of the Longitudinal Study on Adult Health (ELSA-Brasil)
Batista, Thaís Resende
Anticoncepcionais orais
Terapia de Reposição Hormonal
Testes de coagulação sanguínea.
Contraceptives, Oral
Hormone Replacement Therapy
Blood coagulation tests.
Anticonceptivos Orales
Terapia de Reemplazo de Hormonas
Pruebas de coagulación sanguínea.
title_short Association between the use of female hormones and the thrombin generation: Cross-sectional analysis of the Longitudinal Study on Adult Health (ELSA-Brasil)
title_full Association between the use of female hormones and the thrombin generation: Cross-sectional analysis of the Longitudinal Study on Adult Health (ELSA-Brasil)
title_fullStr Association between the use of female hormones and the thrombin generation: Cross-sectional analysis of the Longitudinal Study on Adult Health (ELSA-Brasil)
title_full_unstemmed Association between the use of female hormones and the thrombin generation: Cross-sectional analysis of the Longitudinal Study on Adult Health (ELSA-Brasil)
title_sort Association between the use of female hormones and the thrombin generation: Cross-sectional analysis of the Longitudinal Study on Adult Health (ELSA-Brasil)
author Batista, Thaís Resende
author_facet Batista, Thaís Resende
Barreto, Sandhi Maria
Silva, Ana Paula Ferreira
Oliveira Junior, Wander Valadares de
Maluf, Chams Bicalho
Ribeiro, Antônio Luiz Pinho
Carvalho, Maria das Graças
Figueiredo, Roberta Carvalho de
Rios, Danyelle Romana Alves
author_role author
author2 Barreto, Sandhi Maria
Silva, Ana Paula Ferreira
Oliveira Junior, Wander Valadares de
Maluf, Chams Bicalho
Ribeiro, Antônio Luiz Pinho
Carvalho, Maria das Graças
Figueiredo, Roberta Carvalho de
Rios, Danyelle Romana Alves
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Batista, Thaís Resende
Barreto, Sandhi Maria
Silva, Ana Paula Ferreira
Oliveira Junior, Wander Valadares de
Maluf, Chams Bicalho
Ribeiro, Antônio Luiz Pinho
Carvalho, Maria das Graças
Figueiredo, Roberta Carvalho de
Rios, Danyelle Romana Alves
dc.subject.por.fl_str_mv Anticoncepcionais orais
Terapia de Reposição Hormonal
Testes de coagulação sanguínea.
Contraceptives, Oral
Hormone Replacement Therapy
Blood coagulation tests.
Anticonceptivos Orales
Terapia de Reemplazo de Hormonas
Pruebas de coagulación sanguínea.
topic Anticoncepcionais orais
Terapia de Reposição Hormonal
Testes de coagulação sanguínea.
Contraceptives, Oral
Hormone Replacement Therapy
Blood coagulation tests.
Anticonceptivos Orales
Terapia de Reemplazo de Hormonas
Pruebas de coagulación sanguínea.
description Introduction: The thrombin generation assay (TGA) assesses the risk of developing thrombotic events. The aim of this study was to investigate the association between the use of oral contraceptives (OCs) and hormone therapy (HT) with the TGA and resistance to activated protein C (APC). Methods: Cross-sectional study with women from the Longitudinal Study of Adult Health (ELSA-Brasil). TGA was performed by the CAT method. Results: There was an association between all parameters of the TGA and the use of OCs and an association of lag time and peak time with the use of HT. Conclusion: The TGA allows us to assess the hypercoagulability status and may be useful in the management of female hormones users.
publishDate 2021
dc.date.none.fl_str_mv 2021-08-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/17888
10.33448/rsd-v10i9.17888
url https://rsdjournal.org/index.php/rsd/article/view/17888
identifier_str_mv 10.33448/rsd-v10i9.17888
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/17888/16517
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 9; e12910917888
Research, Society and Development; Vol. 10 Núm. 9; e12910917888
Research, Society and Development; v. 10 n. 9; e12910917888
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052683743395840

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