Vitamin D and infectious diseases in the COVID-19 pandemic outburst
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/4614 |
Resumo: | The new coronavirus pandemic disease (COVID-19) pandemic was first reported in Wuhan, China, in late 2019, and rapidly spread around the world. Considering its fast transmission rate, the new COVID-19 has become a threat to the public health worldwide. Thus, objective ideas based on scientific evidences must be proposed for the treatment of patients infected. Vitamin D is a hormone with important role in the regulation of the immune system functioning. The main sources of Vitamin D are food intake and synthesis process in the organism which starts in the skin through photoreaction with sun exposure. Then, the pre-Vitamin D is isomerized into pro-Vitamin D. Afterwards, it is metabolized in the liver into 25-hydroxivitamin D, and then converted into in the kidney into its active form, the 1.25-dihydroxivitamin D. Due to its pivotal role in the improvement of the immune response, Vitamin D can positively affect the treatment of several infecto-contagious diseases, such as influenza and H1N1. This concise review aims to inform about the use of Vitamin D as a possible ally in the treatment of COVID-19. The studies included in this review point out that Vitamin D can perform immunomodulatory and anti-inflammatory functions, which would significantly improve the treatment of viral infections. Further clinical trials and large populational studies should be carried out in order to better elucidate the effective role of Vitamin D in the treatment of patients with COVID-19. |
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Vitamin D and infectious diseases in the COVID-19 pandemic outburstVitamina D y enfermedades infectocontagiosas en la pandemia de COVID-19Vitamina D e doenças infectocontagiosas na pandemia da COVID-19SARSCoronavírusTratamentoH1N1Influenza.SARSCoronavirusTratamientoH1N1Influenza.SARSCoronavirusTreatmentH1N1Influenza.The new coronavirus pandemic disease (COVID-19) pandemic was first reported in Wuhan, China, in late 2019, and rapidly spread around the world. Considering its fast transmission rate, the new COVID-19 has become a threat to the public health worldwide. Thus, objective ideas based on scientific evidences must be proposed for the treatment of patients infected. Vitamin D is a hormone with important role in the regulation of the immune system functioning. The main sources of Vitamin D are food intake and synthesis process in the organism which starts in the skin through photoreaction with sun exposure. Then, the pre-Vitamin D is isomerized into pro-Vitamin D. Afterwards, it is metabolized in the liver into 25-hydroxivitamin D, and then converted into in the kidney into its active form, the 1.25-dihydroxivitamin D. Due to its pivotal role in the improvement of the immune response, Vitamin D can positively affect the treatment of several infecto-contagious diseases, such as influenza and H1N1. This concise review aims to inform about the use of Vitamin D as a possible ally in the treatment of COVID-19. The studies included in this review point out that Vitamin D can perform immunomodulatory and anti-inflammatory functions, which would significantly improve the treatment of viral infections. Further clinical trials and large populational studies should be carried out in order to better elucidate the effective role of Vitamin D in the treatment of patients with COVID-19.La nueva pandemia de la enfermedad coronavirus (COVID-19) surgió a fines de 2019 en Wuhan, China, y se extendió rápidamente por todo el mundo. Teniendo en cuenta su velocidad de transmisión rápida, COVID-19 se ha convertido en una amenaza para la salud pública en todo el mundo. Por lo tanto, se deben proponer ideas objetivas basadas en evidencia científica para el tratamiento de pacientes infectados. La vitamina D es una hormona que juega un papel importante en la regulación de la función del sistema inmune. Las principales fuentes de obtención de vitamina D son los alimentos y el proceso de síntesis en el cuerpo iniciado en la piel, a través de la fotorreacción mediada por la luz solar, en la que la pre-vitamina D se isomeriza en pro-vitamina D. Posteriormente, se metaboliza en el hígado a 25-hidroxivitamina D, y convertida al riñón en su forma activa, 1,25-dihidroxivitamina D. Debido a su papel clave en la mejora de la respuesta inmune, la vitamina D puede afectar positivamente el tratamiento de diversas enfermedades infecciosas, tales como influenza y H1N1. Esta revisión tiene como objetivo informar sobre el uso de vitamina D como un posible aliado en el tratamiento de COVID-19. Los estudios incluidos en esta revisión indican que la vitamina D puede tener funciones inmunomoduladoras y antiinflamatorias, lo que beneficia significativamente el tratamiento de las infecciones virales. Se recomienda que se realicen ensayos clínicos aleatorios y grandes estudios de población para ayudar a dilucidar el papel efectivo de la vitamina D en el tratamiento de pacientes con COVID-19.A pandemia da doença do novo coronavírus (COVID-19) surgiu no fim de 2019 em Wuhan, China, e rapidamente se alastrou ao redor de todo o globo. Considerando sua rápida taxa de transmissão, a COVID-19 tornou-se uma ameaça à saúde pública mundial. Portanto, ideias objetivas baseadas em evidências científicas devem ser propostas para o tratamento de pacientes infectados. A vitamina D é um hormônio que apresenta função importante na regulação da função do sistema imune. As principais fontes de obtenção da Vitamina D são a alimentação e do processo de síntese no organismo iniciado na pele, através de fotorreação mediada pela luz solar, em que a pré-vitamina D isomeriza-se em pró-vitamina D. Posteriormente, é metabolizada no fígado em 25-hidroxivitamina D, e convertida no rim em sua forma ativa, a 1,25-dihidroxivitamina D. Por conta do seu papel chave na melhoria da resposta imune, a Vitamina D pode afetar positivamente o tratamento de diversas doenças infectocontagiosas, tais como a influenza e H1N1. Esta revisão tem como objetivo informar sobre o uso de Vitamina D como possível aliado no tratamento da COVID-19. Os estudos incluídos nesta revisão apontam que a vitamina D pode exercer funções imunomoduladoras e anti-inflamatórias, que beneficiam significativamente o tratamento de infecções virais. Recomenda-se que ensaios clínicos randomizados e estudos populacionais amplos sejam conduzidos para melohr elucidar o papel efetivo da Vitamina D no tratamento de pacientes com COVID-19.Research, Society and Development2020-06-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/461410.33448/rsd-v9i7.4614Research, Society and Development; Vol. 9 No. 7; e771974614Research, Society and Development; Vol. 9 Núm. 7; e771974614Research, Society and Development; v. 9 n. 7; e7719746142525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/4614/4183Copyright (c) 2020 Valmir Oliveira Silvino, Mayara Maria Lima Pereira, Rayane Carvalho de Moura, Mara Cristina Carvalho Batista, Bruno Viana Rosa, Eduardo Henrique de Moura, Maria do Carmo Carvalho e Martins, Marcos Antônio Pereira dos Santosinfo:eu-repo/semantics/openAccessSilvino, Valmir OliveiraPereira, Mayara Maria LimaMoura, Rayane Carvalho deBatista, Mara Cristina CarvalhoRosa, Bruno VianaMoura, Eduardo Henrique deMartins, Maria do Carmo Carvalho eSantos, Marcos Antônio Pereira dos2020-08-20T18:05:03Zoai:ojs.pkp.sfu.ca:article/4614Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:28:24.637298Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Vitamin D and infectious diseases in the COVID-19 pandemic outburst Vitamina D y enfermedades infectocontagiosas en la pandemia de COVID-19 Vitamina D e doenças infectocontagiosas na pandemia da COVID-19 |
title |
Vitamin D and infectious diseases in the COVID-19 pandemic outburst |
spellingShingle |
Vitamin D and infectious diseases in the COVID-19 pandemic outburst Silvino, Valmir Oliveira SARS Coronavírus Tratamento H1N1 Influenza. SARS Coronavirus Tratamiento H1N1 Influenza. SARS Coronavirus Treatment H1N1 Influenza. |
title_short |
Vitamin D and infectious diseases in the COVID-19 pandemic outburst |
title_full |
Vitamin D and infectious diseases in the COVID-19 pandemic outburst |
title_fullStr |
Vitamin D and infectious diseases in the COVID-19 pandemic outburst |
title_full_unstemmed |
Vitamin D and infectious diseases in the COVID-19 pandemic outburst |
title_sort |
Vitamin D and infectious diseases in the COVID-19 pandemic outburst |
author |
Silvino, Valmir Oliveira |
author_facet |
Silvino, Valmir Oliveira Pereira, Mayara Maria Lima Moura, Rayane Carvalho de Batista, Mara Cristina Carvalho Rosa, Bruno Viana Moura, Eduardo Henrique de Martins, Maria do Carmo Carvalho e Santos, Marcos Antônio Pereira dos |
author_role |
author |
author2 |
Pereira, Mayara Maria Lima Moura, Rayane Carvalho de Batista, Mara Cristina Carvalho Rosa, Bruno Viana Moura, Eduardo Henrique de Martins, Maria do Carmo Carvalho e Santos, Marcos Antônio Pereira dos |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Silvino, Valmir Oliveira Pereira, Mayara Maria Lima Moura, Rayane Carvalho de Batista, Mara Cristina Carvalho Rosa, Bruno Viana Moura, Eduardo Henrique de Martins, Maria do Carmo Carvalho e Santos, Marcos Antônio Pereira dos |
dc.subject.por.fl_str_mv |
SARS Coronavírus Tratamento H1N1 Influenza. SARS Coronavirus Tratamiento H1N1 Influenza. SARS Coronavirus Treatment H1N1 Influenza. |
topic |
SARS Coronavírus Tratamento H1N1 Influenza. SARS Coronavirus Tratamiento H1N1 Influenza. SARS Coronavirus Treatment H1N1 Influenza. |
description |
The new coronavirus pandemic disease (COVID-19) pandemic was first reported in Wuhan, China, in late 2019, and rapidly spread around the world. Considering its fast transmission rate, the new COVID-19 has become a threat to the public health worldwide. Thus, objective ideas based on scientific evidences must be proposed for the treatment of patients infected. Vitamin D is a hormone with important role in the regulation of the immune system functioning. The main sources of Vitamin D are food intake and synthesis process in the organism which starts in the skin through photoreaction with sun exposure. Then, the pre-Vitamin D is isomerized into pro-Vitamin D. Afterwards, it is metabolized in the liver into 25-hydroxivitamin D, and then converted into in the kidney into its active form, the 1.25-dihydroxivitamin D. Due to its pivotal role in the improvement of the immune response, Vitamin D can positively affect the treatment of several infecto-contagious diseases, such as influenza and H1N1. This concise review aims to inform about the use of Vitamin D as a possible ally in the treatment of COVID-19. The studies included in this review point out that Vitamin D can perform immunomodulatory and anti-inflammatory functions, which would significantly improve the treatment of viral infections. Further clinical trials and large populational studies should be carried out in order to better elucidate the effective role of Vitamin D in the treatment of patients with COVID-19. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-06-12 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/4614 10.33448/rsd-v9i7.4614 |
url |
https://rsdjournal.org/index.php/rsd/article/view/4614 |
identifier_str_mv |
10.33448/rsd-v9i7.4614 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/4614/4183 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 9 No. 7; e771974614 Research, Society and Development; Vol. 9 Núm. 7; e771974614 Research, Society and Development; v. 9 n. 7; e771974614 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052650583228416 |