Toxicity and antibacterial activity of medicinal plants used in the treatment of respiratory diseases: an integrative review

Detalhes bibliográficos
Autor(a) principal: Oliveira, Maria Clara Borges de
Data de Publicação: 2020
Outros Autores: Cruz , Celsa Karolayne Silva, Rocha, Gabriel Mauriz de Moura, Brito, Mauro Gustavo Amaral, Oliveira, Guilherme Antônio Lopes de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/7169
Resumo: Objective: to carry out a bibliographic survey on the toxicity profile and antibacterial activity of medicinal plants used in the treatment of respiratory diseases, in order to highlight the main species and chemical constituents, in addition to correlating them with the biological activity of the plants found. Methodology: the study is an integrative literature review, in which the databases established for the research were PubMed, BVS and Science Direct. The descriptors used were Medicinal plants, Respiratory diseases, Phytotherapy, Toxicity and Antibacterial and the defined time frame was from the last 10 years, starting in 2010. Results and Discussion: the final sample consisted of 11 articles and the results obtained were presented in relation to the medicinal species used for the treatment of respiratory diseases, with the phytochemistry of the species and the compounds responsible for biological activity, in addition to the description of the toxicity profile and the antibacterial activity of the plants mentioned in the articles. Only studies addressing the species Pelargonium sidoides, Justicia pectoralis and Luffa operculata presented toxicity studies and data on antibacterial activity. In view of this, these plants exhibited a prevalence of inhibition against gram-positive bacteria, such as Streptococcus pyogenes, and in toxicological tests performed, no toxicity was found. Conclusion: it is necessary to carry out more research with the reported plant species, as there was a shortage of clinical studies and it is also essential that toxicity studies be carried out with plants that did not address this topic.
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spelling Toxicity and antibacterial activity of medicinal plants used in the treatment of respiratory diseases: an integrative reviewToxicidad y actividad antibacteriana de plantas medicinales utilizadas en el tratamiento de enfermedades respiratorias: una revisión integradoraToxicidade e atividade antibacteriana de plantas medicinais utilizadas no tratamento de doenças respiratórias: revisão integrativaMedicinal plantsPhytotherapyRespiratory diseasesToxicityAnti-bacterial.Plantas medicinalesFitoterapiaEnfermedades respiratoriasToxicidadAntibacteriano.Plantas medicinaisFitoterapiaDoenças respiratóriasToxicidadeAntibacteriano. Objective: to carry out a bibliographic survey on the toxicity profile and antibacterial activity of medicinal plants used in the treatment of respiratory diseases, in order to highlight the main species and chemical constituents, in addition to correlating them with the biological activity of the plants found. Methodology: the study is an integrative literature review, in which the databases established for the research were PubMed, BVS and Science Direct. The descriptors used were Medicinal plants, Respiratory diseases, Phytotherapy, Toxicity and Antibacterial and the defined time frame was from the last 10 years, starting in 2010. Results and Discussion: the final sample consisted of 11 articles and the results obtained were presented in relation to the medicinal species used for the treatment of respiratory diseases, with the phytochemistry of the species and the compounds responsible for biological activity, in addition to the description of the toxicity profile and the antibacterial activity of the plants mentioned in the articles. Only studies addressing the species Pelargonium sidoides, Justicia pectoralis and Luffa operculata presented toxicity studies and data on antibacterial activity. In view of this, these plants exhibited a prevalence of inhibition against gram-positive bacteria, such as Streptococcus pyogenes, and in toxicological tests performed, no toxicity was found. Conclusion: it is necessary to carry out more research with the reported plant species, as there was a shortage of clinical studies and it is also essential that toxicity studies be carried out with plants that did not address this topic.Objetivo: realizar una encuesta bibliográfica sobre el perfil de toxicidad y la actividad antibacteriana de las plantas medicinales utilizadas en el tratamiento de enfermedades respiratorias, con el fin de resaltar las principales especies y componentes químicos, además de correlacionarlos con la actividad biológica de las plantas encontradas. Metodología: el estudio es una revisión de literatura integradora, en la cual las bases de datos establecidas para la investigación fueron PubMed, BVS y Science Direct. Los descriptores utilizados fueron Plantas medicinales, Enfermedades respiratorias, Fitoterapia, Toxicidad y Antibacterias y el plazo definido fue de los últimos 10 años, a partir de 2010. Resultados y discusión: la muestra final consistió en 11 artículos y los resultados obtenidos se presentaron en relación con las especies medicinales utilizadas para el tratamiento de enfermedades respiratorias, con la fitoquímica de las especies y los compuestos responsables de la actividad biológica, además de la descripción del perfil de toxicidad y la actividad antibacteriana de las plantas mencionadas en los artículos. Solo los estudios que tratan sobre las especies Pelargonium sidoides, Justicia pectoralis y Luffa operculata presentaron estudios de toxicidad y datos sobre la actividad antibacteriana. En vista de esto, estas plantas exhibieron una prevalencia de inhibición contra bacterias grampositivas, como Streptococcus pyogenes, y las pruebas de toxicidad realizadas no mostraron toxicidad. Conclusión: es necesario realizar más investigaciones con las especies de plantas reportadas, ya que hubo escasez de estudios clínicos y también es esencial que se realicen estudios de toxicidad con plantas que no abordaron este tema.Objetivo: realizar um levantamento bibliográfico sobre o perfil de toxicidade e a atividade antibacteriana de plantas medicinais utilizadas no tratamento de doenças respiratórias, de forma a destacar as principais espécies e os constituintes químicos, além de correlacioná-los com a atividade biológica das plantas encontradas. Metodologia: o estudo trata-se de uma revisão integrativa da literatura, na qual as bases de dados estabelecidas para a pesquisa foram PubMed, BVS e Science Direct. Os descritores utilizados foram Plantas medicinais, Doenças respiratórias, Fitoterapia, Toxicidade e Antibacteriano e o recorte temporal definido foi dos últimos 10 anos, a partir de 2010. Resultados e Discussão: a amostra final foi composta por 11 artigos e os resultados obtidos foram apresentados em relação as espécies medicinais utilizadas para o tratamento de doenças respiratórias, com a fitoquímica da espécie e os compostos responsáveis pela atividade biológica, além da descrição do perfil de toxicidade e a atividade antibacteriana das plantas citadas nos artigos. Apenas os estudos que abordavam sobre as espécies Pelargonium sidoides, Justicia pectoralis e Luffa operculata apresentaram estudos de toxicidade e dados sobre a atividade antibacteriana. Em vista disso, essas plantas exibiram prevalência de inibição frente às bactérias gram-positivas, como Streptococcus pyogenes, e nos testes toxicológicos efetuados não foi evidenciada toxicidade. Conclusão: faz-se necessário a realização de mais pesquisas com as espécies vegetais relatadas, pois observou-se uma escassez de estudos clínicos e também é imprescindível que sejam efetuados estudos de toxicidade com as plantas que não abordaram essa temática.Research, Society and Development2020-08-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/716910.33448/rsd-v9i9.7169Research, Society and Development; Vol. 9 No. 9; e244997169Research, Society and Development; Vol. 9 Núm. 9; e244997169Research, Society and Development; v. 9 n. 9; e2449971692525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/7169/6388Copyright (c) 2020 Maria Clara Borges de Oliveira; Celsa Karolayne Silva Cruz ; Gabriel Mauriz de Moura Rocha; Mauro Gustavo Amaral Brito; Guilherme Antônio Lopes de Oliveirahttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOliveira, Maria Clara Borges de Cruz , Celsa Karolayne SilvaRocha, Gabriel Mauriz de Moura Brito, Mauro Gustavo Amaral Oliveira, Guilherme Antônio Lopes de2020-09-18T01:42:11Zoai:ojs.pkp.sfu.ca:article/7169Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:29:59.610551Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Toxicity and antibacterial activity of medicinal plants used in the treatment of respiratory diseases: an integrative review
Toxicidad y actividad antibacteriana de plantas medicinales utilizadas en el tratamiento de enfermedades respiratorias: una revisión integradora
Toxicidade e atividade antibacteriana de plantas medicinais utilizadas no tratamento de doenças respiratórias: revisão integrativa
title Toxicity and antibacterial activity of medicinal plants used in the treatment of respiratory diseases: an integrative review
spellingShingle Toxicity and antibacterial activity of medicinal plants used in the treatment of respiratory diseases: an integrative review
Oliveira, Maria Clara Borges de
Medicinal plants
Phytotherapy
Respiratory diseases
Toxicity
Anti-bacterial.
Plantas medicinales
Fitoterapia
Enfermedades respiratorias
Toxicidad
Antibacteriano.
Plantas medicinais
Fitoterapia
Doenças respiratórias
Toxicidade
Antibacteriano.
title_short Toxicity and antibacterial activity of medicinal plants used in the treatment of respiratory diseases: an integrative review
title_full Toxicity and antibacterial activity of medicinal plants used in the treatment of respiratory diseases: an integrative review
title_fullStr Toxicity and antibacterial activity of medicinal plants used in the treatment of respiratory diseases: an integrative review
title_full_unstemmed Toxicity and antibacterial activity of medicinal plants used in the treatment of respiratory diseases: an integrative review
title_sort Toxicity and antibacterial activity of medicinal plants used in the treatment of respiratory diseases: an integrative review
author Oliveira, Maria Clara Borges de
author_facet Oliveira, Maria Clara Borges de
Cruz , Celsa Karolayne Silva
Rocha, Gabriel Mauriz de Moura
Brito, Mauro Gustavo Amaral
Oliveira, Guilherme Antônio Lopes de
author_role author
author2 Cruz , Celsa Karolayne Silva
Rocha, Gabriel Mauriz de Moura
Brito, Mauro Gustavo Amaral
Oliveira, Guilherme Antônio Lopes de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Maria Clara Borges de
Cruz , Celsa Karolayne Silva
Rocha, Gabriel Mauriz de Moura
Brito, Mauro Gustavo Amaral
Oliveira, Guilherme Antônio Lopes de
dc.subject.por.fl_str_mv Medicinal plants
Phytotherapy
Respiratory diseases
Toxicity
Anti-bacterial.
Plantas medicinales
Fitoterapia
Enfermedades respiratorias
Toxicidad
Antibacteriano.
Plantas medicinais
Fitoterapia
Doenças respiratórias
Toxicidade
Antibacteriano.
topic Medicinal plants
Phytotherapy
Respiratory diseases
Toxicity
Anti-bacterial.
Plantas medicinales
Fitoterapia
Enfermedades respiratorias
Toxicidad
Antibacteriano.
Plantas medicinais
Fitoterapia
Doenças respiratórias
Toxicidade
Antibacteriano.
description Objective: to carry out a bibliographic survey on the toxicity profile and antibacterial activity of medicinal plants used in the treatment of respiratory diseases, in order to highlight the main species and chemical constituents, in addition to correlating them with the biological activity of the plants found. Methodology: the study is an integrative literature review, in which the databases established for the research were PubMed, BVS and Science Direct. The descriptors used were Medicinal plants, Respiratory diseases, Phytotherapy, Toxicity and Antibacterial and the defined time frame was from the last 10 years, starting in 2010. Results and Discussion: the final sample consisted of 11 articles and the results obtained were presented in relation to the medicinal species used for the treatment of respiratory diseases, with the phytochemistry of the species and the compounds responsible for biological activity, in addition to the description of the toxicity profile and the antibacterial activity of the plants mentioned in the articles. Only studies addressing the species Pelargonium sidoides, Justicia pectoralis and Luffa operculata presented toxicity studies and data on antibacterial activity. In view of this, these plants exhibited a prevalence of inhibition against gram-positive bacteria, such as Streptococcus pyogenes, and in toxicological tests performed, no toxicity was found. Conclusion: it is necessary to carry out more research with the reported plant species, as there was a shortage of clinical studies and it is also essential that toxicity studies be carried out with plants that did not address this topic.
publishDate 2020
dc.date.none.fl_str_mv 2020-08-16
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/7169
10.33448/rsd-v9i9.7169
url https://rsdjournal.org/index.php/rsd/article/view/7169
identifier_str_mv 10.33448/rsd-v9i9.7169
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/7169/6388
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 9 No. 9; e244997169
Research, Society and Development; Vol. 9 Núm. 9; e244997169
Research, Society and Development; v. 9 n. 9; e244997169
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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