Guillain-Barré syndrome associated with COVID-19: a systematic review

Detalhes bibliográficos
Autor(a) principal: Amaral, Maria Eduarda de Azeredo
Data de Publicação: 2021
Outros Autores: Ávila, Lucilla Ribeiro, Amaral, Bernardo Merrighi de Figueiredo, Nasser, Arthur Kalil Santana, Silva , João Pedro Martins e, Taveira, José Hítallo Anchieta
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/22585
Resumo: SARS-CoV-2 is a virus belonging to the coronavirus family and the causative agent of COVID-19. It was discovered in 2019 in Wuhan City, China, it had worldwide dissemination, generating a series of uncertainties regarding its immunopathology and consequences in a short period of time. Among the studies analyzed, there seems to be a possible relationship of previous COVID-19 infection and development of Guillain-Barré Syndrome (GBS), an acute immune polyradiculoneuropathy. The present study with a protocol registered in Open Science (https://osf.io/qe625) aims to analyze the published literature of the mechanism with which COVID-19 can trigger GBS as a secondary framework. To this do so, the methodology of systematic review was used, with data collection performed from March 16, 2021 to March 28, 2021, using individual search strategies described according to Annex 1 in pubmed and embase databases. Inclusion criteria were: articles describing the mechanism of GBS after confirmed SARS-CoV-2 infection, excluding systematic reviews, narrative reviews, literature reviews or meta-analyses, as well as reports with pediatric, hebiatric, obstetric and geriatric patients were not accepted. The results showed 11 articles describing the mechanisms, of which 2 were cohort studies and 9 case reports, all from infected patients with COVID-19 secondarily manifesting GBS. It is concluded that, despite the sparse literature, SARS-CoV-2 can trigger immunoinflammatory responses that trigger a neurological complication picture of GBS.
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spelling Guillain-Barré syndrome associated with COVID-19: a systematic reviewSíndrome de Guillain-Barré asociado con COVID-19: una revisión sistemáticaSíndrome de Guillain-Barré associada à COVID-19: uma revisão sistemáticaInfecções por CoronavirusSARS-CoV-2Síndrome de Guillain-Barré.Coronavirus InfectionsSARS-CoV-2Guillain-Barre Syndrome.Infecciones por CoronavirusSARS-CoV-2Síndrome de Guillain-Barré.SARS-CoV-2 is a virus belonging to the coronavirus family and the causative agent of COVID-19. It was discovered in 2019 in Wuhan City, China, it had worldwide dissemination, generating a series of uncertainties regarding its immunopathology and consequences in a short period of time. Among the studies analyzed, there seems to be a possible relationship of previous COVID-19 infection and development of Guillain-Barré Syndrome (GBS), an acute immune polyradiculoneuropathy. The present study with a protocol registered in Open Science (https://osf.io/qe625) aims to analyze the published literature of the mechanism with which COVID-19 can trigger GBS as a secondary framework. To this do so, the methodology of systematic review was used, with data collection performed from March 16, 2021 to March 28, 2021, using individual search strategies described according to Annex 1 in pubmed and embase databases. Inclusion criteria were: articles describing the mechanism of GBS after confirmed SARS-CoV-2 infection, excluding systematic reviews, narrative reviews, literature reviews or meta-analyses, as well as reports with pediatric, hebiatric, obstetric and geriatric patients were not accepted. The results showed 11 articles describing the mechanisms, of which 2 were cohort studies and 9 case reports, all from infected patients with COVID-19 secondarily manifesting GBS. It is concluded that, despite the sparse literature, SARS-CoV-2 can trigger immunoinflammatory responses that trigger a neurological complication picture of GBS.El SARS-CoV-2 es un virus perteneciente a la familia de los coronavirus y agente causante del COVID-19. Descubierta en el año 2019 en la ciudad de Wuhan, China, tuvo una difusión mundial, generando una serie de incertidumbres respecto a su inmunopatología y consecuencias en un corto periodo de tiempo. Entre los estudios revisados, parece existir una posible relación de la infección previa de COVID-19 y el desarrollo del Síndrome de Guillain-Barré (SGB), una polirradiculoneuropatía inmunológica aguda. El presente estudio con protocolo registrado en el Open Science (https://osf.io/qe625) tiene como objetivo analizar la literatura publicada respecto al mecanismo por el cual el COVID-19 puede desencadenar el SGB como condición secundaria. Para ello, se utilizó la metodología de revisión sistemática, con la recogida de datos realizada desde el 16 de marzo de 2021 hasta el 28 de marzo de 2021, utilizando estrategias de búsqueda individuales descritas según el anexo 1 en las bases de datos PubMed y Embase. Los criterios de inclusión fueron: artículos que describieran el mecanismo del SGB tras una infección confirmada por SARS-CoV-2, excluyendo las revisiones sistemáticas, las revisiones narrativas, las revisiones bibliográficas o los meta-análisis, así como los informes con pacientes pediátricos, hebiáticos, obstétricos y geriátricos. Los resultados mostraron 11 artículos que describían los mecanismos, de los cuales 2 eran estudios de cohortes y 9 informes de casos, todos de pacientes infectados y con COVID-19 que manifestaban secundariamente el SGB. Se concluye que, a pesar de la escasa literatura, el SARS-CoV-2 puede desencadenar respuestas inmunoinflamatorias que desencadenan un cuadro de complicación neurológica del SGB.O SARS-CoV-2 é um vírus pertencente à família dos coronavírus, e agente causador da COVID-19. Foi descoberto no ano de 2019, na cidade de Wuhan, China, teve disseminação mundial, gerando uma série de incertezas com relação à sua imunopatologia e consequências em um curto prazo de tempo. Dentre os estudos analisados, parece existir uma possível relação de infecção prévia da COVID-19 e desenvolvimento da Síndrome de Guillain-Barré (SGB), uma polirradiculoneuropatia imune aguda. O presente estudo com protocolo registrado na Open Science (https://osf.io/qe625) visa analisar a literatura publicada a respeito do mecanismo com o qual a COVID-19 pode desencadear a SGB como quadro secundário. Para isso, utilizou-se a metodologia de revisão sistemática, com coleta de dados realizada do dia 16 de março de 2021 até o dia 28 de março de 2021, utilizando estratégias de buscas individuais descritas de acordo com anexo 1 nas bases de dados da PubMed e Embase. Os critérios de inclusão foram: artigos que descrevessem o mecanismo da SGB após infecção de por SARS-CoV-2 confirmada, excluindo-se revisões sistemáticas, narrativas, de literatura ou metanálises, assim como não foram aceitos relatos com pacientes pediátricos, hebiátricos, obstétricos e geriátricos. Os resultados apresentaram 11 artigos descrevendo os mecanismos, sendo que 2 foram estudos de coorte e 9 relatos de caso, todos de pacientes infectados e com COVID-19 manifestando secundariamente SGB. Conclui-se que, apesar da literatura escassa, o SARS-CoV-2 pode desencadear respostas imunoinflamatórias que desencadeiam um quadro de complicação neurológica de SGB.Research, Society and Development2021-11-24info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2258510.33448/rsd-v10i15.22585Research, Society and Development; Vol. 10 No. 15; e198101522585Research, Society and Development; Vol. 10 Núm. 15; e198101522585Research, Society and Development; v. 10 n. 15; e1981015225852525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/22585/20235Copyright (c) 2021 Maria Eduarda de Azeredo Amaral; Lucilla Ribeiro Ávila; Bernardo Merrighi de Figueiredo Amaral; Arthur Kalil Santana Nasser; João Pedro Martins e Silva ; José Hítallo Anchieta Taveirahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessAmaral, Maria Eduarda de Azeredo Ávila, Lucilla Ribeiro Amaral, Bernardo Merrighi de Figueiredo Nasser, Arthur Kalil Santana Silva , João Pedro Martins e Taveira, José Hítallo Anchieta 2021-12-06T10:13:53Zoai:ojs.pkp.sfu.ca:article/22585Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:41:42.631914Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Guillain-Barré syndrome associated with COVID-19: a systematic review
Síndrome de Guillain-Barré asociado con COVID-19: una revisión sistemática
Síndrome de Guillain-Barré associada à COVID-19: uma revisão sistemática
title Guillain-Barré syndrome associated with COVID-19: a systematic review
spellingShingle Guillain-Barré syndrome associated with COVID-19: a systematic review
Amaral, Maria Eduarda de Azeredo
Infecções por Coronavirus
SARS-CoV-2
Síndrome de Guillain-Barré.
Coronavirus Infections
SARS-CoV-2
Guillain-Barre Syndrome.
Infecciones por Coronavirus
SARS-CoV-2
Síndrome de Guillain-Barré.
title_short Guillain-Barré syndrome associated with COVID-19: a systematic review
title_full Guillain-Barré syndrome associated with COVID-19: a systematic review
title_fullStr Guillain-Barré syndrome associated with COVID-19: a systematic review
title_full_unstemmed Guillain-Barré syndrome associated with COVID-19: a systematic review
title_sort Guillain-Barré syndrome associated with COVID-19: a systematic review
author Amaral, Maria Eduarda de Azeredo
author_facet Amaral, Maria Eduarda de Azeredo
Ávila, Lucilla Ribeiro
Amaral, Bernardo Merrighi de Figueiredo
Nasser, Arthur Kalil Santana
Silva , João Pedro Martins e
Taveira, José Hítallo Anchieta
author_role author
author2 Ávila, Lucilla Ribeiro
Amaral, Bernardo Merrighi de Figueiredo
Nasser, Arthur Kalil Santana
Silva , João Pedro Martins e
Taveira, José Hítallo Anchieta
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Amaral, Maria Eduarda de Azeredo
Ávila, Lucilla Ribeiro
Amaral, Bernardo Merrighi de Figueiredo
Nasser, Arthur Kalil Santana
Silva , João Pedro Martins e
Taveira, José Hítallo Anchieta
dc.subject.por.fl_str_mv Infecções por Coronavirus
SARS-CoV-2
Síndrome de Guillain-Barré.
Coronavirus Infections
SARS-CoV-2
Guillain-Barre Syndrome.
Infecciones por Coronavirus
SARS-CoV-2
Síndrome de Guillain-Barré.
topic Infecções por Coronavirus
SARS-CoV-2
Síndrome de Guillain-Barré.
Coronavirus Infections
SARS-CoV-2
Guillain-Barre Syndrome.
Infecciones por Coronavirus
SARS-CoV-2
Síndrome de Guillain-Barré.
description SARS-CoV-2 is a virus belonging to the coronavirus family and the causative agent of COVID-19. It was discovered in 2019 in Wuhan City, China, it had worldwide dissemination, generating a series of uncertainties regarding its immunopathology and consequences in a short period of time. Among the studies analyzed, there seems to be a possible relationship of previous COVID-19 infection and development of Guillain-Barré Syndrome (GBS), an acute immune polyradiculoneuropathy. The present study with a protocol registered in Open Science (https://osf.io/qe625) aims to analyze the published literature of the mechanism with which COVID-19 can trigger GBS as a secondary framework. To this do so, the methodology of systematic review was used, with data collection performed from March 16, 2021 to March 28, 2021, using individual search strategies described according to Annex 1 in pubmed and embase databases. Inclusion criteria were: articles describing the mechanism of GBS after confirmed SARS-CoV-2 infection, excluding systematic reviews, narrative reviews, literature reviews or meta-analyses, as well as reports with pediatric, hebiatric, obstetric and geriatric patients were not accepted. The results showed 11 articles describing the mechanisms, of which 2 were cohort studies and 9 case reports, all from infected patients with COVID-19 secondarily manifesting GBS. It is concluded that, despite the sparse literature, SARS-CoV-2 can trigger immunoinflammatory responses that trigger a neurological complication picture of GBS.
publishDate 2021
dc.date.none.fl_str_mv 2021-11-24
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/22585
10.33448/rsd-v10i15.22585
url https://rsdjournal.org/index.php/rsd/article/view/22585
identifier_str_mv 10.33448/rsd-v10i15.22585
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/22585/20235
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 15; e198101522585
Research, Society and Development; Vol. 10 Núm. 15; e198101522585
Research, Society and Development; v. 10 n. 15; e198101522585
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
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instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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