Biological activities and chemical profile from Batis maritima (Bataceae), a halophyte species with bioprospecting potential
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/23726 |
Resumo: | Halophytes are salt-tolerant plants, enriched in metabolic compounds with several industrial applications. Batis maritima is a halophyte with occurrence in tropical and subtropical zones and the present work aimed to investigate B. maritima leaves extract for biotechnology and bioprospecting approaches. The present study evaluated the phytochemical profile, the role of acetylcholinesterase, and protective activities from B. maritima. The phytochemical screening highlighted the presence of phenolic compounds, anthracenes, and saponins. The metal content analysis revealed sodium (Na) as the most abundant salt (1 g/kg), followed by Al (0.35 g/kg), and several other elements in lower concentrations. Further, DPPH and TAC methodologies showed an significant antioxidant activity (IC50 5.17 ± 0.05 μg/mL and 0.45 ± 0.08 mg.AAEm, respectively). A metal chelating activity was also observed, with IC50 25.76 ± 0.3 μg/mL. Additionally, B. maritima aqueous extract disclosed an anticholinesterase inhibitory effect in a dose-dependent manner (IC50 = 0.0023 mg/mL). Haemolysis assay did not reveal any toxic effects. On the other hand, the cytotoxicity assay, using murine fibroblasts cells (NIH-3T3), showed a decrease in cell viability at high concentrations. |
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Biological activities and chemical profile from Batis maritima (Bataceae), a halophyte species with bioprospecting potential Actividades biológicas y perfil químico de Batis maritima (Bataceae), especie con gran potencial para la bioprospeccionAtividades biológicas e perfil químico de Batis maritima (Bataceae), uma espécie halófita com potencial para bioprospecçãoActividad antioxidanteBatis maritimaCaracterización fitoquímicaCitotoxicidadConcentración de metales.Atividade AntioxidanteBatis maritimaCaracterização fitoquímicaCitotoxicidadeConcentração de metais. Antioxidant activityBatis maritimaCytotoxic activityMetal contentPhytochemical characterization.Halophytes are salt-tolerant plants, enriched in metabolic compounds with several industrial applications. Batis maritima is a halophyte with occurrence in tropical and subtropical zones and the present work aimed to investigate B. maritima leaves extract for biotechnology and bioprospecting approaches. The present study evaluated the phytochemical profile, the role of acetylcholinesterase, and protective activities from B. maritima. The phytochemical screening highlighted the presence of phenolic compounds, anthracenes, and saponins. The metal content analysis revealed sodium (Na) as the most abundant salt (1 g/kg), followed by Al (0.35 g/kg), and several other elements in lower concentrations. Further, DPPH and TAC methodologies showed an significant antioxidant activity (IC50 5.17 ± 0.05 μg/mL and 0.45 ± 0.08 mg.AAEm, respectively). A metal chelating activity was also observed, with IC50 25.76 ± 0.3 μg/mL. Additionally, B. maritima aqueous extract disclosed an anticholinesterase inhibitory effect in a dose-dependent manner (IC50 = 0.0023 mg/mL). Haemolysis assay did not reveal any toxic effects. On the other hand, the cytotoxicity assay, using murine fibroblasts cells (NIH-3T3), showed a decrease in cell viability at high concentrations.Los halófitos son plantas tolerantes a la sal, enriquecidas en compuestos metabólicos con varias aplicaciones industriales. Batis maritima es un halófito con presencia en zonas tropicales y subtropicales y el presente trabajo tuvo como objetivo investigar el extracto de hojas de B. maritima para enfoques de biotecnología y bioprospección. El presente estudio evaluó el perfil fitoquímico, el papel frente a la acetilcolinesterasa y las actividades protectoras de B. maritima. El cribado fitoquímico destacó la presencia de compuestos fenólicos, antracenos y saponinas. El análisis del contenido de metales reveló que el sodio (Na) es la sal más abundante (1 g/kg), seguida del Al (0,35 g/kg) y varios otros elementos en menor concentración. Además, las metodologías DPPH y TAC mostraron una actividad antioxidante significativa (IC50 5.17 ± 0.05 μg/mL y 0.45 ± 0.08 mg.AAEm, respectivamente). También se observó una actividad quelante de metales, con IC50 = 25,760 ± 0,3 μg / mL. Además, el extracto acuoso de B. maritima reveló un efecto anticolinesterasa de una manera dependiente de la dosis (IC50 = 0,0023 mg / ml). El ensayo de hemólisis no reveló ningún efecto tóxico. Por otro lado, el ensayo de citotoxicidad, utilizando células de fibroblastos murinos (NIH-3T3), mostró una disminución de la viabilidad celular.Halófitas são plantas tolerantes a salinidade, ricas em metabolitos com aplicação em diversas indústrias. Batis maritima é uma halófita com ocorrência em zonas tropicais e subtropicais, o presente trabalho objetivou investigar o extrato das folhas de B. maritima em uma abordagem de bioprospecção e biotecnológica. O presente estudo avaliou o perfil fitoquímico, o potencial efeito sobre a enzima acetilcolinesterase, além de propriedades protetivas de B. maritima. A análise fitoquímica evidenciou a presença de compostos fenólicos, antracenos e saponinas. O conteúdo de metal revelou o Sódio (Na) como o sal mais abundante (1g/Kg), seguido pelo alumínio (Al;0,35 g/Kg), e diversos outros elementos em concentrações menores. As metodologias de DPPH e Capacidade Antioxidante Total indicou efeito antioxidante significativo (IC50 5,17 ± 0,05 μg/mL e 0,45 ± 0,08 mg.AAEm, respectivamente). A atividade quelante de metal também foi observada, com um IC50 de 25,76 ± 0,3 μg/mL. Além disso, o extrato aquoso de B. maritima apresentou efeito inibitório sobre a acetilcolinesterase de forma dose-dependente com IC50 de 0,0023 mg/mL. O ensaio de hemólise não revelou efeitos tóxicos, por outro lado, o ensaio de citotoxicidade, utilizando células da linhagem NIH-3T3, evidenciou uma diminuição da viabilidade celular em concentrações elevadas do extrato.Research, Society and Development2021-12-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2372610.33448/rsd-v10i16.23726Research, Society and Development; Vol. 10 No. 16; e391101623726Research, Society and Development; Vol. 10 Núm. 16; e391101623726Research, Society and Development; v. 10 n. 16; e3911016237262525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/23726/22644Copyright (c) 2021 Bruno Ricardo Scopel; Paulo Henrique Oliveira de Miranda; Ricardo Sérgio da Silva; João Victor de Oliveira Alves; Bruno Oliveira de Veras; Luciclaudio Cassimiro Amorim; Michelle Melgarejo da Rosa; Jorge Irapuan de Souza Barbosa; Maria Rita Cabral Sales de Melo; Ranilson de Souza Bezerra; Márcia Vanusa da Silvahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessScopel, Bruno RicardoMiranda, Paulo Henrique Oliveira deSilva, Ricardo Sérgio da Alves, João Victor de Oliveira Veras, Bruno Oliveira deAmorim, Luciclaudio CassimiroRosa, Michelle Melgarejo daBarbosa, Jorge Irapuan de SouzaMelo, Maria Rita Cabral Sales de Bezerra, Ranilson de Souza Silva, Márcia Vanusa da 2021-12-20T11:03:07Zoai:ojs.pkp.sfu.ca:article/23726Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:42:30.457655Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Biological activities and chemical profile from Batis maritima (Bataceae), a halophyte species with bioprospecting potential Actividades biológicas y perfil químico de Batis maritima (Bataceae), especie con gran potencial para la bioprospeccion Atividades biológicas e perfil químico de Batis maritima (Bataceae), uma espécie halófita com potencial para bioprospecção |
| title |
Biological activities and chemical profile from Batis maritima (Bataceae), a halophyte species with bioprospecting potential |
| spellingShingle |
Biological activities and chemical profile from Batis maritima (Bataceae), a halophyte species with bioprospecting potential Scopel, Bruno Ricardo Actividad antioxidante Batis maritima Caracterización fitoquímica Citotoxicidad Concentración de metales. Atividade Antioxidante Batis maritima Caracterização fitoquímica Citotoxicidade Concentração de metais. Antioxidant activity Batis maritima Cytotoxic activity Metal content Phytochemical characterization. |
| title_short |
Biological activities and chemical profile from Batis maritima (Bataceae), a halophyte species with bioprospecting potential |
| title_full |
Biological activities and chemical profile from Batis maritima (Bataceae), a halophyte species with bioprospecting potential |
| title_fullStr |
Biological activities and chemical profile from Batis maritima (Bataceae), a halophyte species with bioprospecting potential |
| title_full_unstemmed |
Biological activities and chemical profile from Batis maritima (Bataceae), a halophyte species with bioprospecting potential |
| title_sort |
Biological activities and chemical profile from Batis maritima (Bataceae), a halophyte species with bioprospecting potential |
| author |
Scopel, Bruno Ricardo |
| author_facet |
Scopel, Bruno Ricardo Miranda, Paulo Henrique Oliveira de Silva, Ricardo Sérgio da Alves, João Victor de Oliveira Veras, Bruno Oliveira de Amorim, Luciclaudio Cassimiro Rosa, Michelle Melgarejo da Barbosa, Jorge Irapuan de Souza Melo, Maria Rita Cabral Sales de Bezerra, Ranilson de Souza Silva, Márcia Vanusa da |
| author_role |
author |
| author2 |
Miranda, Paulo Henrique Oliveira de Silva, Ricardo Sérgio da Alves, João Victor de Oliveira Veras, Bruno Oliveira de Amorim, Luciclaudio Cassimiro Rosa, Michelle Melgarejo da Barbosa, Jorge Irapuan de Souza Melo, Maria Rita Cabral Sales de Bezerra, Ranilson de Souza Silva, Márcia Vanusa da |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Scopel, Bruno Ricardo Miranda, Paulo Henrique Oliveira de Silva, Ricardo Sérgio da Alves, João Victor de Oliveira Veras, Bruno Oliveira de Amorim, Luciclaudio Cassimiro Rosa, Michelle Melgarejo da Barbosa, Jorge Irapuan de Souza Melo, Maria Rita Cabral Sales de Bezerra, Ranilson de Souza Silva, Márcia Vanusa da |
| dc.subject.por.fl_str_mv |
Actividad antioxidante Batis maritima Caracterización fitoquímica Citotoxicidad Concentración de metales. Atividade Antioxidante Batis maritima Caracterização fitoquímica Citotoxicidade Concentração de metais. Antioxidant activity Batis maritima Cytotoxic activity Metal content Phytochemical characterization. |
| topic |
Actividad antioxidante Batis maritima Caracterización fitoquímica Citotoxicidad Concentración de metales. Atividade Antioxidante Batis maritima Caracterização fitoquímica Citotoxicidade Concentração de metais. Antioxidant activity Batis maritima Cytotoxic activity Metal content Phytochemical characterization. |
| description |
Halophytes are salt-tolerant plants, enriched in metabolic compounds with several industrial applications. Batis maritima is a halophyte with occurrence in tropical and subtropical zones and the present work aimed to investigate B. maritima leaves extract for biotechnology and bioprospecting approaches. The present study evaluated the phytochemical profile, the role of acetylcholinesterase, and protective activities from B. maritima. The phytochemical screening highlighted the presence of phenolic compounds, anthracenes, and saponins. The metal content analysis revealed sodium (Na) as the most abundant salt (1 g/kg), followed by Al (0.35 g/kg), and several other elements in lower concentrations. Further, DPPH and TAC methodologies showed an significant antioxidant activity (IC50 5.17 ± 0.05 μg/mL and 0.45 ± 0.08 mg.AAEm, respectively). A metal chelating activity was also observed, with IC50 25.76 ± 0.3 μg/mL. Additionally, B. maritima aqueous extract disclosed an anticholinesterase inhibitory effect in a dose-dependent manner (IC50 = 0.0023 mg/mL). Haemolysis assay did not reveal any toxic effects. On the other hand, the cytotoxicity assay, using murine fibroblasts cells (NIH-3T3), showed a decrease in cell viability at high concentrations. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-12-14 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/23726 10.33448/rsd-v10i16.23726 |
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https://rsdjournal.org/index.php/rsd/article/view/23726 |
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10.33448/rsd-v10i16.23726 |
| dc.language.iso.fl_str_mv |
eng |
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eng |
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https://rsdjournal.org/index.php/rsd/article/view/23726/22644 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development; Vol. 10 No. 16; e391101623726 Research, Society and Development; Vol. 10 Núm. 16; e391101623726 Research, Society and Development; v. 10 n. 16; e391101623726 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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1797052759561732096 |