Photodynamic therapy in the treatment of injuries in non-melanoma skin cancer: integrative review

Detalhes bibliográficos
Autor(a) principal: Silva, Vanessa Bernardino da
Data de Publicação: 2021
Outros Autores: Souza, Sônia Regina de, Codá, Rosane de Paula, Fabrício, Bruna Silva, Sória, Denise de Assis Corrêa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/11257
Resumo: Cancer is the second leading cause of death in the world, and in Brazil, skin cancer is the neoplasia with the highest incidence, which corresponds to about 30% of diagnosed cases. Non-melanoma skin cancer is the most prevalent in the country, but despite the high incidence, it is the one with the lowest lethality. Photodynamic Therapy (PDT) is a topical treatment that causes the selective destruction of neoplastic cells through a photochemical reaction and has been used worldwide in the treatment of several types of cancer, including non-melanoma. The purpose of this review is to identify the contributions of photodynamic therapy in the treatment of lesions in non-melanoma cancer over the past eleven years. It is an integrative review through a search in the Lilacs, SciELO and Medline databases, using the descriptors Photochemotherapy; Skin Neoplasms; Carcinoma, Basal Cell; and Carcinoma, Squamous Cell. PDT with 5-aminolevulinic acid (ALA) and methyl aminolevulinate hydrochloride (MAL) showed similar efficacy and sometimes higher than the conventional therapies in several studies, each with their selectivity and ability to penetrate the tissue. The choice of treatment for the individual must take into account their unique characteristics and the characteristics of the tumor, not excluding the monitoring of a multidisciplinary team and early diagnosis of skin cancer.
id UNIFEI_52d594c8bc935eb3b394cd319dcbc985
oai_identifier_str oai:ojs.pkp.sfu.ca:article/11257
network_acronym_str UNIFEI
network_name_str Research, Society and Development
repository_id_str
spelling Photodynamic therapy in the treatment of injuries in non-melanoma skin cancer: integrative reviewTerapia fotodinámica en el tratamiento de lesiones en cáncer de piel no melanoma: revisión integradoraTerapia fotodinâmica no tratamento de lesões em câncer de pele não melanoma: revisão integrativaIntegrative reviewPhotochemotherapySkin neoplasmsCarcinoma.Revision integradoraFotoquimioterapiaNeoplasias cutaneasCarcinoma.Revisao integrativaFotoquimioterapiaNeoplasias cutaneasCarcinoma.Cancer is the second leading cause of death in the world, and in Brazil, skin cancer is the neoplasia with the highest incidence, which corresponds to about 30% of diagnosed cases. Non-melanoma skin cancer is the most prevalent in the country, but despite the high incidence, it is the one with the lowest lethality. Photodynamic Therapy (PDT) is a topical treatment that causes the selective destruction of neoplastic cells through a photochemical reaction and has been used worldwide in the treatment of several types of cancer, including non-melanoma. The purpose of this review is to identify the contributions of photodynamic therapy in the treatment of lesions in non-melanoma cancer over the past eleven years. It is an integrative review through a search in the Lilacs, SciELO and Medline databases, using the descriptors Photochemotherapy; Skin Neoplasms; Carcinoma, Basal Cell; and Carcinoma, Squamous Cell. PDT with 5-aminolevulinic acid (ALA) and methyl aminolevulinate hydrochloride (MAL) showed similar efficacy and sometimes higher than the conventional therapies in several studies, each with their selectivity and ability to penetrate the tissue. The choice of treatment for the individual must take into account their unique characteristics and the characteristics of the tumor, not excluding the monitoring of a multidisciplinary team and early diagnosis of skin cancer.El cáncer es la segunda causa de muerte en el mundo, y en Brasil, el cáncer de piel es la neoplasia con mayor incidencia, que corresponde a alrededor del 30% de los casos diagnosticados. El cáncer de piel no melanoma es el más prevalente en el país, pero a pesar de su alta incidencia, es el de menor letalidad. La terapia fotodinámica (TFD) es un tratamiento tópico que provoca la destrucción selectiva de células neoplásicas mediante una reacción fotoquímica y se ha utilizado en todo el mundo en el tratamiento de varios tipos de cáncer, incluido el no melanoma. El propósito de esta revisión es identificar las contribuciones de la terapia fotodinámica en el tratamiento de las lesiones en el cáncer no melanoma durante los últimos once años. Se trata de una revisión integradora mediante una búsqueda en las bases de datos Lilacs, SciELO y Medline, utilizando los descriptores Fotoquimioterapia; Neoplasias Cutáneas; Carcinoma Basocelular y Carcinoma de Células Escamosas. La TFD con ácido 5-aminolevulínico (ALA) y metil éster de ácido levulínico (MAL) ha demostrado una eficacia similar y, a veces, mayor que las terapias convencionales en varios estudios, cada uno con su selectividad y capacidad para penetrar en el tejido. La elección del tratamiento para el individuo debe tener en cuenta sus características únicas y las características del tumor, sin excluir el seguimiento de un equipo multidisciplinar y el diagnóstico precoz del cáncer de piel.O câncer é a segunda maior causa de morte no mundo, e no Brasil, o câncer de pele é a neoplasia de maior incidência, o que corresponde a cerca de 30% dos casos diagnosticados. O câncer de pele do tipo não-melanoma é o mais incidente no país, mas apesar da alta incidência, é o de menor letalidade. A terapia fotodinâmica (TFD) é um tratamento tópico que causa a destruição seletiva de células neoplásicas por meio de uma reação fotoquímica e, vem sendo utilizada em todo o mundo no tratamento de diversos tipos de câncer, dentre eles o não melanoma. O objetivo desta revisão é identificar quais as contribuições da terapia fotodinâmica no tratamento das lesões em câncer não melanoma ao longo dos últimos onze anos. Trata-se de uma revisão integrativa através de uma busca nas bases de dados Lilacs, SciELO e Medline, utilizando os descritores Fotoquimioterapia; Neoplasias Cutâneas; Carcinoma Basocelular e Carcinoma de Células Escamosas. A TFD com o ácido-5-aminolevulínico (ALA) e o cloridrato de aminolevulinato de metila (MAL), mostrou uma eficácia semelhante e por vezes maior do que as terapias convencionais em diversos estudos, cada qual com sua seletividade e capacidade de penetração tecidual. A escolha do tratamento para o indivíduo, deve levar em conta suas características singulares e as características do tumor, não descartando o acompanhamento de uma equipe multiprofissional e diagnóstico precoce do câncer de pele.Research, Society and Development2021-01-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1125710.33448/rsd-v10i1.11257Research, Society and Development; Vol. 10 No. 1; e7410111257Research, Society and Development; Vol. 10 Núm. 1; e7410111257Research, Society and Development; v. 10 n. 1; e74101112572525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/11257/10269Copyright (c) 2021 Vanessa Bernardino da Silva; Sônia Regina de Souza; Rosane de Paula Codá; Bruna Silva Fabrício; Denise de Assis Corrêa Sóriahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSilva, Vanessa Bernardino daSouza, Sônia Regina deCodá, Rosane de PaulaFabrício, Bruna SilvaSória, Denise de Assis Corrêa2021-02-20T21:19:23Zoai:ojs.pkp.sfu.ca:article/11257Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:33:08.024468Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Photodynamic therapy in the treatment of injuries in non-melanoma skin cancer: integrative review
Terapia fotodinámica en el tratamiento de lesiones en cáncer de piel no melanoma: revisión integradora
Terapia fotodinâmica no tratamento de lesões em câncer de pele não melanoma: revisão integrativa
title Photodynamic therapy in the treatment of injuries in non-melanoma skin cancer: integrative review
spellingShingle Photodynamic therapy in the treatment of injuries in non-melanoma skin cancer: integrative review
Silva, Vanessa Bernardino da
Integrative review
Photochemotherapy
Skin neoplasms
Carcinoma.
Revision integradora
Fotoquimioterapia
Neoplasias cutaneas
Carcinoma.
Revisao integrativa
Fotoquimioterapia
Neoplasias cutaneas
Carcinoma.
title_short Photodynamic therapy in the treatment of injuries in non-melanoma skin cancer: integrative review
title_full Photodynamic therapy in the treatment of injuries in non-melanoma skin cancer: integrative review
title_fullStr Photodynamic therapy in the treatment of injuries in non-melanoma skin cancer: integrative review
title_full_unstemmed Photodynamic therapy in the treatment of injuries in non-melanoma skin cancer: integrative review
title_sort Photodynamic therapy in the treatment of injuries in non-melanoma skin cancer: integrative review
author Silva, Vanessa Bernardino da
author_facet Silva, Vanessa Bernardino da
Souza, Sônia Regina de
Codá, Rosane de Paula
Fabrício, Bruna Silva
Sória, Denise de Assis Corrêa
author_role author
author2 Souza, Sônia Regina de
Codá, Rosane de Paula
Fabrício, Bruna Silva
Sória, Denise de Assis Corrêa
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silva, Vanessa Bernardino da
Souza, Sônia Regina de
Codá, Rosane de Paula
Fabrício, Bruna Silva
Sória, Denise de Assis Corrêa
dc.subject.por.fl_str_mv Integrative review
Photochemotherapy
Skin neoplasms
Carcinoma.
Revision integradora
Fotoquimioterapia
Neoplasias cutaneas
Carcinoma.
Revisao integrativa
Fotoquimioterapia
Neoplasias cutaneas
Carcinoma.
topic Integrative review
Photochemotherapy
Skin neoplasms
Carcinoma.
Revision integradora
Fotoquimioterapia
Neoplasias cutaneas
Carcinoma.
Revisao integrativa
Fotoquimioterapia
Neoplasias cutaneas
Carcinoma.
description Cancer is the second leading cause of death in the world, and in Brazil, skin cancer is the neoplasia with the highest incidence, which corresponds to about 30% of diagnosed cases. Non-melanoma skin cancer is the most prevalent in the country, but despite the high incidence, it is the one with the lowest lethality. Photodynamic Therapy (PDT) is a topical treatment that causes the selective destruction of neoplastic cells through a photochemical reaction and has been used worldwide in the treatment of several types of cancer, including non-melanoma. The purpose of this review is to identify the contributions of photodynamic therapy in the treatment of lesions in non-melanoma cancer over the past eleven years. It is an integrative review through a search in the Lilacs, SciELO and Medline databases, using the descriptors Photochemotherapy; Skin Neoplasms; Carcinoma, Basal Cell; and Carcinoma, Squamous Cell. PDT with 5-aminolevulinic acid (ALA) and methyl aminolevulinate hydrochloride (MAL) showed similar efficacy and sometimes higher than the conventional therapies in several studies, each with their selectivity and ability to penetrate the tissue. The choice of treatment for the individual must take into account their unique characteristics and the characteristics of the tumor, not excluding the monitoring of a multidisciplinary team and early diagnosis of skin cancer.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-03
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/11257
10.33448/rsd-v10i1.11257
url https://rsdjournal.org/index.php/rsd/article/view/11257
identifier_str_mv 10.33448/rsd-v10i1.11257
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/11257/10269
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 1; e7410111257
Research, Society and Development; Vol. 10 Núm. 1; e7410111257
Research, Society and Development; v. 10 n. 1; e7410111257
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052667168555008

Registros relacionados