Vitamin D in the prevention and treatment of periodontal diseases: an integrative review

• Autor(a) principal: Layber, Marlon Mezadri
• Data de Publicação: 2021
• Outros Autores: Goés, Alyne Barreto Mesquita de, Villarim, Camila Vilar de Oliveira, Caldas, Diego Maia Diógenes Rabelo, Araújo-Neto, Irami, Silva, Laura Cristina Costa e, Rêgo, Amália Cinthia Meneses, Araújo-Filho, Irami
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Research, Society and Development
• DOI: 10.33448/rsd-v10i13.20738
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/20738
• topic: Enfermedades periodontales; Desmineralización ósea patológica; Patología bucal; Receptores de calcitriol; Vitamina D.; Doenças periodontais; Desmineralização patológica óssea; Patologia oral; Receptores de calcitriol; Vitamina D.; Calcitriol receptors; Oral pathology; Pathologic bone demineralization; Periodontal diseases; Vitamin D.

Introduction: Vitamin D is synthesized from 7-dehydrocholesterol during a photochemical reaction, under the effect of ultraviolet radiation on the skin, obtained from food. It is hydroxylated in the liver to 25-hydroxyvitamin D3 (25(OH)D3). It is an active metabolite, which maintains the balance of calcium and phosphorus concentration in the blood, in addition to helping bone remodeling. Vitamin D deficiency promotes rickets in children and osteoporosis in adults, with a risk of bone fracture. Vitamin D acts in the pathogenesis of periodontal diseases via immunomodulation, increases mineral density and reduces bone resorption, which is important in combating agents that cause periodontal diseases. Objectives: Evaluate the importance of vitamin D in the prevention and treatment of periodontal diseases. Methods: A search was carried out in the PubMed/Medline, Scopus, Scielo, Embase, Web of Science and Google Scholar databases on scientifically proven evidence on the subject. Results: The present review demonstrated the importance of vitamin D in the prevention and treatment of periodontitis and the consequences of its deficiency on the oral health of patients. Conclusion: Vitamin D plays an important role in oral homeostasis and vitamin deficiency results in periodontal disease.