Antioxidant potential of flavonoids and therapeutic applications

Detalhes bibliográficos
Autor(a) principal: Moraes, Giovanna Vizzaccaro
Data de Publicação: 2022
Outros Autores: Jorge, Gabriel Marcomini, Gonzaga, Rodrigo Vieira, Santos, Deny Anderson dos
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/36225
Resumo: Objective: a systematic review was carried out and the relevance of a natural class of secondary metabolites, the flavonoids, present in several species of the plant kingdom, such as apples, cabbage, grapes, onions and broccoli, was demonstrated, aiming at the possible development of future effective drugs against several diseases considered public health problems. Methodology: the identification of articles was based on research of scientific works published in PubMed, SciELO and Google Scholar. Articles were included that addressed the general concepts of flavonoids, focusing on their antioxidant activity, free radical activity, action of reactive oxygen species and function of vitamins C and E. Results and discussion: 31 articles, with varying results according to the clinical trials performed, their characteristics and specific objectives, demonstrating general characteristics of flavonoids and their main therapeutic applications. Conclusions: it was possible to observe the main characteristics of flavonoids such as their basic structure, their different classes and therapeutic applications, mainly their antioxidant activity.
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spelling Antioxidant potential of flavonoids and therapeutic applicationsPotencial antioxidante de los flavonoides y aplicaciones terapêuticasPotencial antioxidante dos flavonoides e aplicações terapêuticasFlavonoidesAntioxidanteTerapéuticoRadicales libresEspecies reactivas de oxígeno.FlavonoidesAntioxidanteTerapêuticoRadicais livresEspécies reativas de oxigênio.FlavonoidsAntioxidantTherapeuticFree radicalsOxigen-reactive species.Objective: a systematic review was carried out and the relevance of a natural class of secondary metabolites, the flavonoids, present in several species of the plant kingdom, such as apples, cabbage, grapes, onions and broccoli, was demonstrated, aiming at the possible development of future effective drugs against several diseases considered public health problems. Methodology: the identification of articles was based on research of scientific works published in PubMed, SciELO and Google Scholar. Articles were included that addressed the general concepts of flavonoids, focusing on their antioxidant activity, free radical activity, action of reactive oxygen species and function of vitamins C and E. Results and discussion: 31 articles, with varying results according to the clinical trials performed, their characteristics and specific objectives, demonstrating general characteristics of flavonoids and their main therapeutic applications. Conclusions: it was possible to observe the main characteristics of flavonoids such as their basic structure, their different classes and therapeutic applications, mainly their antioxidant activity.Objetivo: se realizó una revisión sistemática y se demostró la relevancia de una clase natural de metabolitos secundarios, los flavonoides, presentes em muchas especies del reino vegetal, como manzanas, coles, uvas, cebollas y brócoli, buscando el posible desarrollo de futuros medicamentos efectivos contra varias enfermedades consideradas problemas de salud pública. Metodología: la identificación de los artículos se basó en la investigación de trabajos científicos publicados en PubMed, SciELO y Google Scholar. Se incluyeron artículos que abordaban los conceptos generales de los flavonoides, enfocándose en su actividad antioxidante, actividad de radicales libres, acción de especies reactivas de oxígeno y función de las vitaminas C y E. Resultados y discusión: 31 artículos, con resultados variables según los ensayos clínicos realizados, sus características y objetivos específicos, demostrando las características generales de los flavonoides y sus principales aplicaciones terapéuticas. Conclusiones: se pudo observar las principales características de los flavonoides como su estructura básica, sus diferentes clases y aplicaciones terapéuticas, principalmente su actividad antioxidante.Objetivo: realizou-se uma revisão integrativa e demonstrou-se a relevância de uma classe natural de metabólitos secundários, os flavonoides, presentes em diversas espécies do reino vegetal, como maçã, repolho, uva, cebola e brócolis, visando o possível desenvolvimento de futuros medicamentos eficazes contra diversas doenças consideradas problemas de saúde pública. Metodologia: a identificação dos artigos foi baseada em pesquisas de trabalhos científicos publicados no PubMed, SciELO e Google Acadêmico. Foram incluídos artigos que abordaram os conceitos gerais dos flavonoides, com foco em sua atividade antioxidante, atividade dos radicais livres, ação das espécies reativas de oxigênio e função das vitaminas C e E. Resultados e discussão: 31 artigos, com resultados variados conforme os ensaios clínicos realizados e suas características e objetivos específicos, demonstrando características gerais dos flavonoides e suas principais aplicações terapêuticas. Conclusões: foi possível observar as principais características dos flavonoides como sua estrutura básica, suas diferentes classes e aplicações terapêuticas, principalmente, sua atividade antioxidante.Research, Society and Development2022-10-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3622510.33448/rsd-v11i14.36225Research, Society and Development; Vol. 11 No. 14; e238111436225Research, Society and Development; Vol. 11 Núm. 14; e238111436225Research, Society and Development; v. 11 n. 14; e2381114362252525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/36225/30290Copyright (c) 2022 Giovanna Vizzaccaro Moraes; Gabriel Marcomini Jorge; Rodrigo Vieira Gonzaga; Deny Anderson dos Santoshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMoraes, Giovanna VizzaccaroJorge, Gabriel MarcominiGonzaga, Rodrigo VieiraSantos, Deny Anderson dos2022-11-08T13:36:27Zoai:ojs.pkp.sfu.ca:article/36225Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:50:51.434640Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Antioxidant potential of flavonoids and therapeutic applications
Potencial antioxidante de los flavonoides y aplicaciones terapêuticas
Potencial antioxidante dos flavonoides e aplicações terapêuticas
title Antioxidant potential of flavonoids and therapeutic applications
spellingShingle Antioxidant potential of flavonoids and therapeutic applications
Moraes, Giovanna Vizzaccaro
Flavonoides
Antioxidante
Terapéutico
Radicales libres
Especies reactivas de oxígeno.
Flavonoides
Antioxidante
Terapêutico
Radicais livres
Espécies reativas de oxigênio.
Flavonoids
Antioxidant
Therapeutic
Free radicals
Oxigen-reactive species.
title_short Antioxidant potential of flavonoids and therapeutic applications
title_full Antioxidant potential of flavonoids and therapeutic applications
title_fullStr Antioxidant potential of flavonoids and therapeutic applications
title_full_unstemmed Antioxidant potential of flavonoids and therapeutic applications
title_sort Antioxidant potential of flavonoids and therapeutic applications
author Moraes, Giovanna Vizzaccaro
author_facet Moraes, Giovanna Vizzaccaro
Jorge, Gabriel Marcomini
Gonzaga, Rodrigo Vieira
Santos, Deny Anderson dos
author_role author
author2 Jorge, Gabriel Marcomini
Gonzaga, Rodrigo Vieira
Santos, Deny Anderson dos
author2_role author
author
author
dc.contributor.author.fl_str_mv Moraes, Giovanna Vizzaccaro
Jorge, Gabriel Marcomini
Gonzaga, Rodrigo Vieira
Santos, Deny Anderson dos
dc.subject.por.fl_str_mv Flavonoides
Antioxidante
Terapéutico
Radicales libres
Especies reactivas de oxígeno.
Flavonoides
Antioxidante
Terapêutico
Radicais livres
Espécies reativas de oxigênio.
Flavonoids
Antioxidant
Therapeutic
Free radicals
Oxigen-reactive species.
topic Flavonoides
Antioxidante
Terapéutico
Radicales libres
Especies reactivas de oxígeno.
Flavonoides
Antioxidante
Terapêutico
Radicais livres
Espécies reativas de oxigênio.
Flavonoids
Antioxidant
Therapeutic
Free radicals
Oxigen-reactive species.
description Objective: a systematic review was carried out and the relevance of a natural class of secondary metabolites, the flavonoids, present in several species of the plant kingdom, such as apples, cabbage, grapes, onions and broccoli, was demonstrated, aiming at the possible development of future effective drugs against several diseases considered public health problems. Methodology: the identification of articles was based on research of scientific works published in PubMed, SciELO and Google Scholar. Articles were included that addressed the general concepts of flavonoids, focusing on their antioxidant activity, free radical activity, action of reactive oxygen species and function of vitamins C and E. Results and discussion: 31 articles, with varying results according to the clinical trials performed, their characteristics and specific objectives, demonstrating general characteristics of flavonoids and their main therapeutic applications. Conclusions: it was possible to observe the main characteristics of flavonoids such as their basic structure, their different classes and therapeutic applications, mainly their antioxidant activity.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-25
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/36225
10.33448/rsd-v11i14.36225
url https://rsdjournal.org/index.php/rsd/article/view/36225
identifier_str_mv 10.33448/rsd-v11i14.36225
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/36225/30290
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 14; e238111436225
Research, Society and Development; Vol. 11 Núm. 14; e238111436225
Research, Society and Development; v. 11 n. 14; e238111436225
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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