Pathophysiological, clinical and treatment repercussions of Wernicke's Encephalopathy: a review

• Autor(a) principal: Fonseca, Gustavo Soares Gomes Barros
• Data de Publicação: 2021
• Outros Autores: Assunção, Izabely Lima, Pacheco, Luyla Oliveira Paes Landim, Freitas Júnior, Wellington Ubaldino de, Trindade, Patrielly Oliveira, Sodré Neto Segundo, Ademar, Rego, Cecília Pessoa Almeida, Silva, Janyne Daniel da Cunha França da, Aguiar, Rebeca Carvalho de, Borges, Fernando de Abreu, Coelho, Claudia Nery do Nascimento, Costa, Ana Clara Nóbrega, Garcia, Ana Clara Rocha, Freire, Vivianne Maria Laranjeiras Monte, Marinho, Luana Caroline Oliveira, Lima, Pedro de Lacerda, Andrade, Pietra Possapp, Maia, Ana Vitória Feitosa Barroso, Bonfim, Lais Lima, Silva, Mikael Coutinho, Carvalho, Bárbara Nussrala, Carmo, Fernanda Soares Rezende, Silva, Vanessa Marques da, Abreu, David Brusaca, Leite, Maria Julia Fonseca Lima, Machado, Paula Soares, Costa, Arthur Brício Silva, Gonçalves , Rafael Pavão
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/23857
• topic: Wernicke's encephalopathy; Classical triad; Alcoholism.; Encefalopatía de Wernicke; Tríada clásica; Alcoholismo.; Encefalopatia de Wernicke; Tríade clássica; Alcoolismo.

Among the encephalopathies, some have been more studied in recent decades, such as Wernicke's encephalopathy (WE), which is a set of neuropsychiatric signs and symptoms that result from a nutritional deficiency of thiamine. This research is a systematic bibliographic review, of the quantitative type, which used the platforms PubMed, Scientific Electronic Library Online (SciELO) and Google Scholar as a database for researching scientific articles. Literature published with a time frame from 2016 to 2021, in English, that addressed Wernicke's Encephalopathy and its pathophysiological and clinical aspects were used. Therefore, it was found that the deficiency of thiamine (vitamin B1) is able to lead the patient to develop Wernicke's encephalopathy, when the disease is associated with anterograde amnesia. Furthermore, the underlying condition described in WE is alcoholism. Therefore, high doses of parenteral thiamine in high-risk patients are essential for the patient's gradual improvement.