Streptomyces hygroscopicus oil extract with activities against Aedes aegypti

Detalhes bibliográficos
Autor(a) principal: Oliveira, Jackelly Felipe de
Data de Publicação: 2023
Outros Autores: Rique, Hyago Luiz, Nunes, Fabíola da Cruz, Silva, Leonor Alves de Oliveira da
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/40490
Resumo: The arboviruses transmitted by the female Aedes aegypti are considered a public health problem and the vector control is essential to reduce the spread of disease-causing pathogens. The main objective of this research was to investigate the chemical composition of the Streptomyces hygroscopicus biomass extract and its larvicidal capabilities against the Aedes aegypti mosquito. Regarding the result of the prospection of the chemical composition of the extract, based on the qualitative colorimetric methodology of the presence of secondary metabolites, there was a positive indication for the alkaloid test and a negative one for flavonoids. Through Gas Chromatography coupled to mass spectrometry it was possible to infer the presence of 9-12-octadecadienoic acid followed by the presence of 9-12-octadecadienoic acid and linoleic acid. The larvicidal activity against Ae. aegypti (LC50) of the extract diluted with 1% DMSO was 155.4 ppm, the highest mortality was with 250ppm reaching 100 porcent. Finally, it was seen that the oily extract of S. hygroscopicus biomass was able to act on Ae. aegypti, showing as a potential larvicidal for this species.
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spelling Streptomyces hygroscopicus oil extract with activities against Aedes aegypti Extracto oleoso de Streptomyces hygroscopicus con actividad contra larvas de Aedes aegyptiExtrato Oleoso de Streptomyces hygroscopicus com atividades contra as larvas de Aedes aegypti BioinsecticideGas chromatographySecondary metabolites.BioinsecticidaCromatografía de gasesMetabolitos secundarios.BioinseticidaCromatografia gasosaMetabólitos secundários.The arboviruses transmitted by the female Aedes aegypti are considered a public health problem and the vector control is essential to reduce the spread of disease-causing pathogens. The main objective of this research was to investigate the chemical composition of the Streptomyces hygroscopicus biomass extract and its larvicidal capabilities against the Aedes aegypti mosquito. Regarding the result of the prospection of the chemical composition of the extract, based on the qualitative colorimetric methodology of the presence of secondary metabolites, there was a positive indication for the alkaloid test and a negative one for flavonoids. Through Gas Chromatography coupled to mass spectrometry it was possible to infer the presence of 9-12-octadecadienoic acid followed by the presence of 9-12-octadecadienoic acid and linoleic acid. The larvicidal activity against Ae. aegypti (LC50) of the extract diluted with 1% DMSO was 155.4 ppm, the highest mortality was with 250ppm reaching 100 porcent. Finally, it was seen that the oily extract of S. hygroscopicus biomass was able to act on Ae. aegypti, showing as a potential larvicidal for this species.Los arbovirus transmitidos por la hembra Aedes aegypti son considerados un problema de salud pública. El control de vectores es esencial para reducir la propagación de patógenos causantes de enfermedades. El objetivo de esta investigación fue investigar la composición química del extracto de biomasa de Streptomyces hygroscopicus y sus capacidades larvicidas contra el mosquito Aedes aegypti. En cuanto al resultado de la prospección de la composición química del extracto, con base en la metodología colorimétrica cualitativa de presencia de metabolitos secundarios, se obtuvo un indicador positivo para la prueba de alcaloides y negativo para flavonoides. Además, mediante cromatografía de gases acoplada a espectrometría de masas, se pudo inferir la presencia, en mayor cantidad, de ácido 9-12-octadecadienoico, seguido de la presencia de ácido 9-12-octadecadienoico y ácido linoleico. En cuanto a la actividad larvicida frente a Ae. aegypti, la CL50 del extracto diluido con DMSO al 1% fue de 155,4 ppm, la mayor mortalidad fue con 250 ppm llegando al 100%. Finalmente, se vio que el extracto oleoso de biomasa de S. hygroscopicus fue capaz de actuar sobre Ae. aegypti, mostrándose como una potencial larvicida para esta especie.Arboviroses transmitidas pela fêmea do Aedes aegypti são consideradas um problema de saúde pública. Dessa forma, o controle vetorial é essencial para a diminuição da disseminação dos patógenos causadores de doenças. O objetivo desta pesquisa foi investigar a composição química do extrato da biomassa de Streptomyces hygroscopicus e suas capacidades larvicidas para Aedes aegypti. Em relação ao resultado da prospecção da composição química do extrato, com base na metodologia qualitativa colorimétrica da presença de metabólitos secundários, houve indicativo positivo para o teste de alcalóides e negativo para flavonoides. Ademais, por intermédio da Cromatografia Gasosa acoplada à espectrometria de massas foi possível inferir a presença, em maior quantidade, do ácido 9-12-octadecadienóico, seguindo pela presença do ácido 9-12-octadecadienóico e do ácido linoleico. Em relação a atividade larvicida contra Ae. aegypti, a CL50 do extrato diluído com DMSO a 1% foi de 155,4 ppm e a mortalidade máxima foi de 100% em 250 ppm. Por fim, foi visto que o extrato oleoso da biomassa de S. hygroscopicus foi capaz de atuar nas larvas de Ae. aegypti, mostrando-se como potencial larvicida para essa espécie.Research, Society and Development2023-03-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4049010.33448/rsd-v12i3.40490Research, Society and Development; Vol. 12 No. 3; e17412340490Research, Society and Development; Vol. 12 Núm. 3; e17412340490Research, Society and Development; v. 12 n. 3; e174123404902525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/40490/33165Copyright (c) 2023 Jackelly Felipe de Oliveira; Hyago Luiz Rique; Fabíola da Cruz Nunes; Leonor Alves de Oliveira da Silvahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessOliveira, Jackelly Felipe de Rique, Hyago Luiz Nunes, Fabíola da Cruz Silva, Leonor Alves de Oliveira da 2023-03-23T08:33:38Zoai:ojs.pkp.sfu.ca:article/40490Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2023-03-23T08:33:38Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Streptomyces hygroscopicus oil extract with activities against Aedes aegypti
Extracto oleoso de Streptomyces hygroscopicus con actividad contra larvas de Aedes aegypti
Extrato Oleoso de Streptomyces hygroscopicus com atividades contra as larvas de Aedes aegypti
title Streptomyces hygroscopicus oil extract with activities against Aedes aegypti
spellingShingle Streptomyces hygroscopicus oil extract with activities against Aedes aegypti
Oliveira, Jackelly Felipe de
Bioinsecticide
Gas chromatography
Secondary metabolites.
Bioinsecticida
Cromatografía de gases
Metabolitos secundarios.
Bioinseticida
Cromatografia gasosa
Metabólitos secundários.
title_short Streptomyces hygroscopicus oil extract with activities against Aedes aegypti
title_full Streptomyces hygroscopicus oil extract with activities against Aedes aegypti
title_fullStr Streptomyces hygroscopicus oil extract with activities against Aedes aegypti
title_full_unstemmed Streptomyces hygroscopicus oil extract with activities against Aedes aegypti
title_sort Streptomyces hygroscopicus oil extract with activities against Aedes aegypti
author Oliveira, Jackelly Felipe de
author_facet Oliveira, Jackelly Felipe de
Rique, Hyago Luiz
Nunes, Fabíola da Cruz
Silva, Leonor Alves de Oliveira da
author_role author
author2 Rique, Hyago Luiz
Nunes, Fabíola da Cruz
Silva, Leonor Alves de Oliveira da
author2_role author
author
author
dc.contributor.author.fl_str_mv Oliveira, Jackelly Felipe de
Rique, Hyago Luiz
Nunes, Fabíola da Cruz
Silva, Leonor Alves de Oliveira da
dc.subject.por.fl_str_mv Bioinsecticide
Gas chromatography
Secondary metabolites.
Bioinsecticida
Cromatografía de gases
Metabolitos secundarios.
Bioinseticida
Cromatografia gasosa
Metabólitos secundários.
topic Bioinsecticide
Gas chromatography
Secondary metabolites.
Bioinsecticida
Cromatografía de gases
Metabolitos secundarios.
Bioinseticida
Cromatografia gasosa
Metabólitos secundários.
description The arboviruses transmitted by the female Aedes aegypti are considered a public health problem and the vector control is essential to reduce the spread of disease-causing pathogens. The main objective of this research was to investigate the chemical composition of the Streptomyces hygroscopicus biomass extract and its larvicidal capabilities against the Aedes aegypti mosquito. Regarding the result of the prospection of the chemical composition of the extract, based on the qualitative colorimetric methodology of the presence of secondary metabolites, there was a positive indication for the alkaloid test and a negative one for flavonoids. Through Gas Chromatography coupled to mass spectrometry it was possible to infer the presence of 9-12-octadecadienoic acid followed by the presence of 9-12-octadecadienoic acid and linoleic acid. The larvicidal activity against Ae. aegypti (LC50) of the extract diluted with 1% DMSO was 155.4 ppm, the highest mortality was with 250ppm reaching 100 porcent. Finally, it was seen that the oily extract of S. hygroscopicus biomass was able to act on Ae. aegypti, showing as a potential larvicidal for this species.
publishDate 2023
dc.date.none.fl_str_mv 2023-03-06
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/40490
10.33448/rsd-v12i3.40490
url https://rsdjournal.org/index.php/rsd/article/view/40490
identifier_str_mv 10.33448/rsd-v12i3.40490
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/40490/33165
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 12 No. 3; e17412340490
Research, Society and Development; Vol. 12 Núm. 3; e17412340490
Research, Society and Development; v. 12 n. 3; e17412340490
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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