Can postbiotics show antiviral effects against Sars-CoV-2?
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/17259 |
Resumo: | Severe Acute Respiratory Syndrome of Coronavirus-2 (Sars-CoV-2) is the causative agent of the new Coronavirus Disease (COVID-19) responsible for the current pandemic that threatens global health. Although some anti-COVID-19 therapeutic agents are under investigation, there is still no evidence of antiviral action against Sars-CoV-2. Research in the literature describes the success of probiotics in the treatment of viral infections from their byproducts, known as postbiotics, such as exopolysaccharides, hydrogen peroxide, and different bacteriocins. Based on these reports, we describe the main postbiotics that present antiviral actions against different viruses with a view to suggesting their use as possible therapeutic agents for COVID-19. The revised data show promising effects for using postbiotics as efficient vehicles against various types of viruses. However, further investigation of the underlying mechanisms is required for their indication against Sars-CoV-2 and other Sars-CoV infections. |
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Can postbiotics show antiviral effects against Sars-CoV-2?Pueden los postbióticos mostrar efectos antivirales contra Sars-CoV-2? Podem os pós-bióticos apresentarem efeitos antivirais contra Sars-CoV-2?Antiviral activityCOVID-19New coronavirusProbiotic.Actividad antiviralCOVID-19Nuevo coronavirusProbióticos. Atividade antiviralCOVID-19Novo coronavírusProbióticos.Severe Acute Respiratory Syndrome of Coronavirus-2 (Sars-CoV-2) is the causative agent of the new Coronavirus Disease (COVID-19) responsible for the current pandemic that threatens global health. Although some anti-COVID-19 therapeutic agents are under investigation, there is still no evidence of antiviral action against Sars-CoV-2. Research in the literature describes the success of probiotics in the treatment of viral infections from their byproducts, known as postbiotics, such as exopolysaccharides, hydrogen peroxide, and different bacteriocins. Based on these reports, we describe the main postbiotics that present antiviral actions against different viruses with a view to suggesting their use as possible therapeutic agents for COVID-19. The revised data show promising effects for using postbiotics as efficient vehicles against various types of viruses. However, further investigation of the underlying mechanisms is required for their indication against Sars-CoV-2 and other Sars-CoV infections.El Síndrome Respiratorio Agudo Severo por Coronavirus-2 (Sars-CoV-2) es el agente causante de la nueva Enfermedad por Coronavirus (COVID-19) responsable de la pandemia actual que amenaza la salud global. Aunque se están investigando algunos agentes terapéuticos anti-COVID-19, todavía no hay evidencia de acción antiviral contra Sars-CoV-2. Los estudios en la literatura describen el éxito de los probióticos en el tratamiento de infecciones virales causadas por sus subproductos, conocidos como posbióticos, como exopolisacáridos, peróxido de hidrógeno y varias bacteriocinas. Con base en estos informes, describimos los principales post-bióticos que presentan acción antiviral frente a diferentes virus, con el objetivo de sugerir su uso como posibles agentes terapéuticos para COVID-19. Los datos revisados muestran efectos prometedores para el uso de postbióticos como vehículos eficientes contra varios tipos de virus. Sin embargo, se necesita más investigación de los mecanismos subyacentes para su indicación contra Sars-CoV-2 y otras infecciones por Sars-CoV.A Síndrome Respiratória Aguda Grave do Coronavírus-2 (Sars-CoV-2) é o agente causador da nova Doença do Coronavírus (COVID-19) responsável pela atual pandemia que ameaça a saúde global. Embora alguns agentes terapêuticos anti-COVID-19 estejam sob investigação, ainda não há evidências de ação antiviral contra Sars-CoV-2. Pesquisas na literatura descrevem o sucesso dos probióticos no tratamento das infecções virais de seus subprodutos, conhecidos como pós-bióticos, como exopolissacarídeos, peróxido de hidrogênio e diversas bacteriocinas. Com base nesses relatos, descrevemos os principais pós-bióticos que apresentam ação antiviral contra diferentes vírus, com o objetivo de sugerir seu uso como possíveis agentes terapêuticos para COVID-19. Os dados revisados mostram efeitos promissores para o uso de pós-bióticos como veículos eficientes contra vários tipos de vírus. No entanto, uma investigação mais aprofundada dos mecanismos subjacentes é necessária para sua indicação contra Sars-CoV-2 e outras infecções por Sars-CoV.Research, Society and Development2021-07-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1725910.33448/rsd-v10i8.17259Research, Society and Development; Vol. 10 No. 8; e14610817259Research, Society and Development; Vol. 10 Núm. 8; e14610817259Research, Society and Development; v. 10 n. 8; e146108172592525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/17259/15343Copyright (c) 2021 Leandro Paes de Brito; José Noé da Silva Júnior ; Priscila Danielly Santos de Barros; Elaine Cristina da Silva; Priscilla Régia de Andrade Calaça; Maria Taciana Cavalcanti Vieira Soares; Ana Lúcia Figueiredo Portohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBrito, Leandro Paes de Silva Júnior , José Noé da Barros, Priscila Danielly Santos deSilva, Elaine Cristina da Calaça, Priscilla Régia de Andrade Soares, Maria Taciana Cavalcanti Vieira Porto, Ana Lúcia Figueiredo 2021-08-21T18:46:59Zoai:ojs.pkp.sfu.ca:article/17259Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:37:38.384134Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Can postbiotics show antiviral effects against Sars-CoV-2? Pueden los postbióticos mostrar efectos antivirales contra Sars-CoV-2? Podem os pós-bióticos apresentarem efeitos antivirais contra Sars-CoV-2? |
title |
Can postbiotics show antiviral effects against Sars-CoV-2? |
spellingShingle |
Can postbiotics show antiviral effects against Sars-CoV-2? Brito, Leandro Paes de Antiviral activity COVID-19 New coronavirus Probiotic. Actividad antiviral COVID-19 Nuevo coronavirus Probióticos. Atividade antiviral COVID-19 Novo coronavírus Probióticos. |
title_short |
Can postbiotics show antiviral effects against Sars-CoV-2? |
title_full |
Can postbiotics show antiviral effects against Sars-CoV-2? |
title_fullStr |
Can postbiotics show antiviral effects against Sars-CoV-2? |
title_full_unstemmed |
Can postbiotics show antiviral effects against Sars-CoV-2? |
title_sort |
Can postbiotics show antiviral effects against Sars-CoV-2? |
author |
Brito, Leandro Paes de |
author_facet |
Brito, Leandro Paes de Silva Júnior , José Noé da Barros, Priscila Danielly Santos de Silva, Elaine Cristina da Calaça, Priscilla Régia de Andrade Soares, Maria Taciana Cavalcanti Vieira Porto, Ana Lúcia Figueiredo |
author_role |
author |
author2 |
Silva Júnior , José Noé da Barros, Priscila Danielly Santos de Silva, Elaine Cristina da Calaça, Priscilla Régia de Andrade Soares, Maria Taciana Cavalcanti Vieira Porto, Ana Lúcia Figueiredo |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Brito, Leandro Paes de Silva Júnior , José Noé da Barros, Priscila Danielly Santos de Silva, Elaine Cristina da Calaça, Priscilla Régia de Andrade Soares, Maria Taciana Cavalcanti Vieira Porto, Ana Lúcia Figueiredo |
dc.subject.por.fl_str_mv |
Antiviral activity COVID-19 New coronavirus Probiotic. Actividad antiviral COVID-19 Nuevo coronavirus Probióticos. Atividade antiviral COVID-19 Novo coronavírus Probióticos. |
topic |
Antiviral activity COVID-19 New coronavirus Probiotic. Actividad antiviral COVID-19 Nuevo coronavirus Probióticos. Atividade antiviral COVID-19 Novo coronavírus Probióticos. |
description |
Severe Acute Respiratory Syndrome of Coronavirus-2 (Sars-CoV-2) is the causative agent of the new Coronavirus Disease (COVID-19) responsible for the current pandemic that threatens global health. Although some anti-COVID-19 therapeutic agents are under investigation, there is still no evidence of antiviral action against Sars-CoV-2. Research in the literature describes the success of probiotics in the treatment of viral infections from their byproducts, known as postbiotics, such as exopolysaccharides, hydrogen peroxide, and different bacteriocins. Based on these reports, we describe the main postbiotics that present antiviral actions against different viruses with a view to suggesting their use as possible therapeutic agents for COVID-19. The revised data show promising effects for using postbiotics as efficient vehicles against various types of viruses. However, further investigation of the underlying mechanisms is required for their indication against Sars-CoV-2 and other Sars-CoV infections. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-07-09 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/17259 10.33448/rsd-v10i8.17259 |
url |
https://rsdjournal.org/index.php/rsd/article/view/17259 |
identifier_str_mv |
10.33448/rsd-v10i8.17259 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/17259/15343 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 8; e14610817259 Research, Society and Development; Vol. 10 Núm. 8; e14610817259 Research, Society and Development; v. 10 n. 8; e14610817259 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052681826598912 |