Effects of vitamin D on the prevention and treatment of COVID 19: a systematic review
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Data de Publicação: | 2020 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/11174 |
Resumo: | Introduction: Currently, the world has faced one of the largest pandemies with SARS-CoV-2, which causes the COVID-19 disease. It is notorious that its clinical spectrum has a wide variation, ranging from asymptomatic infections to severe conditions. Among some potential factors being correlated by research with infection and disease severity is vitamin D. Thus, the present study aims to understand the effects of vitamin D on the prevention and treatment of COVID-19. Methods: A systematic review of the literature was conducted in the PubMed, Cochrane and Scielo databases, based on articles published in 2019 and 2020. Of the 319 articles identified, 7 were selected from observational studies and one clinical trial. Results: Few studies are available to date, and studies have brought controversial results, since observational studies have associated that low vitamin D levels could interfere with the prevention and severity of the disease, but others have not observed associations. Conclusion: There is still no scientific basis for establishing a causal relationship between vitamin D levels and SARS-CoV-2 infection, whether in prevention, treatment or mortality. Therefore, further studies are needed to understand how these factors interact. |
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Effects of vitamin D on the prevention and treatment of COVID 19: a systematic reviewEfectos de la vitamina D en la prevención y el tratamiento de COVID 19: una revisión sistemáticaEfeitos da vitamina D na prevenção e tratamento da COVID 19: uma revisão sistemáticaInfecções por CoronavirusDeficiência de Vitamina DTerapia NutricionalPrevençãoCOVID-19Tratamento.Coronavirus InfectionsVitamin D DeficiencyNutritional TherapyPreventionCOVID-19Treatment.Infecciones por CoronavirusDeficiencia de Vitamina DTerapia NutricionalPrevenciónCOVID-19Tratamiento.Introduction: Currently, the world has faced one of the largest pandemies with SARS-CoV-2, which causes the COVID-19 disease. It is notorious that its clinical spectrum has a wide variation, ranging from asymptomatic infections to severe conditions. Among some potential factors being correlated by research with infection and disease severity is vitamin D. Thus, the present study aims to understand the effects of vitamin D on the prevention and treatment of COVID-19. Methods: A systematic review of the literature was conducted in the PubMed, Cochrane and Scielo databases, based on articles published in 2019 and 2020. Of the 319 articles identified, 7 were selected from observational studies and one clinical trial. Results: Few studies are available to date, and studies have brought controversial results, since observational studies have associated that low vitamin D levels could interfere with the prevention and severity of the disease, but others have not observed associations. Conclusion: There is still no scientific basis for establishing a causal relationship between vitamin D levels and SARS-CoV-2 infection, whether in prevention, treatment or mortality. Therefore, further studies are needed to understand how these factors interact.Introduccion: Actualmente, el mundo se ha enfrentado a una de las mayores pandemies con SARS-CoV-2, que causa la enfermedad COVID-19. Es notorio que su espectro clínico tiene una amplia variación, que van desde infecciones asintomáticas a condiciones severas. Entre algunos factores potenciales que se correlacionan con la investigación con la infección y la gravedad de la enfermedad es la vitamina D. Por lo tanto, el presente estudio tiene como objetivo comprender los efectos de la vitamina D en la prevención y tratamiento de COVID-19. Metodos: Se llevó a cabo una revisión sistemática de la literatura en las bases de datos PubMed, Cochrane y Scielo, basada en artículos publicados en 2019 y 2020. De los 319 artículos identificados, 7 fueron seleccionados de estudios observacionales y un ensayo clínico. Resultados: Pocos estudios están disponibles hasta la fecha, y los estudios han dado resultados controvertidos, ya que los estudios observacionales han asociado que los bajos niveles de vitamina D podrían interferir con la prevención y la gravedad de la enfermedad, pero otros no han observado asociaciones. Conclusion: Todavía no hay base científica para establecer una relación causal entre los niveles de vitamina D y la infección por SARS-CoV-2, ya sea en prevención, tratamiento o mortalidad. Por lo tanto, se necesitan más estudios para entender cómo interactúan estos factores.Introdução: Atualmente, o mundo tem enfrentado uma das maiores pandemias com o SARS-CoV-2, causador da doença COVID-19. É notório que seu espectro clínico tem uma grande variação, indo de infecções assintomáticas a quadros graves. Dentre alguns fatores em potencial sendo correlacionados pelas pesquisas com a infecção e gravidade da doença, está a vitamina D. Assim, o presente estudo tem por objetivo compreender os efeitos da vitamina D na prevenção e no tratamento da COVID-19. Métodos: Realizou-se revisão sistemática da literatura nas bases de dados PubMed, Cochrane e Scielo, feita a partir de artigos publicados no período de 2019 e 2020. De 319 artigos identificados, 7 foram selecionados, dentre estudos observacionais e um ensaio clínico. Resultados: Poucas pesquisas estão disponíveis até o momento, e estudos trouxeram resultados controversos, visto que pesquisas observacionais associaram que os níveis baixos de vitamina D poderiam interferir na prevenção e na gravidade da doença, porém, outras não observaram associações. Conclusão: Ainda não há embasamento científico para que se estabeleça uma relação causal entre os níveis de vitamina D e a infecção pelo SARS-CoV-2, seja na prevenção, tratamento ou mortalidade. Portanto, são necessários mais estudos para compreensão de como esses fatores interagem.Research, Society and Development2020-12-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1117410.33448/rsd-v9i12.11174Research, Society and Development; Vol. 9 No. 12; e32191211174Research, Society and Development; Vol. 9 Núm. 12; e32191211174Research, Society and Development; v. 9 n. 12; e321912111742525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/11174/9969Copyright (c) 2020 Thiago Poss Moreira; Victor de Souza Costa; Lirane Elize Defante Ferreto; Guilherme Welter Wendthttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMoreira, Thiago PossCosta, Victor de Souza Ferreto, Lirane Elize DefanteWendt, Guilherme Welter2020-12-30T23:32:22Zoai:ojs.pkp.sfu.ca:article/11174Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:33:04.445160Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Effects of vitamin D on the prevention and treatment of COVID 19: a systematic review Efectos de la vitamina D en la prevención y el tratamiento de COVID 19: una revisión sistemática Efeitos da vitamina D na prevenção e tratamento da COVID 19: uma revisão sistemática |
title |
Effects of vitamin D on the prevention and treatment of COVID 19: a systematic review |
spellingShingle |
Effects of vitamin D on the prevention and treatment of COVID 19: a systematic review Moreira, Thiago Poss Infecções por Coronavirus Deficiência de Vitamina D Terapia Nutricional Prevenção COVID-19 Tratamento. Coronavirus Infections Vitamin D Deficiency Nutritional Therapy Prevention COVID-19 Treatment. Infecciones por Coronavirus Deficiencia de Vitamina D Terapia Nutricional Prevención COVID-19 Tratamiento. |
title_short |
Effects of vitamin D on the prevention and treatment of COVID 19: a systematic review |
title_full |
Effects of vitamin D on the prevention and treatment of COVID 19: a systematic review |
title_fullStr |
Effects of vitamin D on the prevention and treatment of COVID 19: a systematic review |
title_full_unstemmed |
Effects of vitamin D on the prevention and treatment of COVID 19: a systematic review |
title_sort |
Effects of vitamin D on the prevention and treatment of COVID 19: a systematic review |
author |
Moreira, Thiago Poss |
author_facet |
Moreira, Thiago Poss Costa, Victor de Souza Ferreto, Lirane Elize Defante Wendt, Guilherme Welter |
author_role |
author |
author2 |
Costa, Victor de Souza Ferreto, Lirane Elize Defante Wendt, Guilherme Welter |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Moreira, Thiago Poss Costa, Victor de Souza Ferreto, Lirane Elize Defante Wendt, Guilherme Welter |
dc.subject.por.fl_str_mv |
Infecções por Coronavirus Deficiência de Vitamina D Terapia Nutricional Prevenção COVID-19 Tratamento. Coronavirus Infections Vitamin D Deficiency Nutritional Therapy Prevention COVID-19 Treatment. Infecciones por Coronavirus Deficiencia de Vitamina D Terapia Nutricional Prevención COVID-19 Tratamiento. |
topic |
Infecções por Coronavirus Deficiência de Vitamina D Terapia Nutricional Prevenção COVID-19 Tratamento. Coronavirus Infections Vitamin D Deficiency Nutritional Therapy Prevention COVID-19 Treatment. Infecciones por Coronavirus Deficiencia de Vitamina D Terapia Nutricional Prevención COVID-19 Tratamiento. |
description |
Introduction: Currently, the world has faced one of the largest pandemies with SARS-CoV-2, which causes the COVID-19 disease. It is notorious that its clinical spectrum has a wide variation, ranging from asymptomatic infections to severe conditions. Among some potential factors being correlated by research with infection and disease severity is vitamin D. Thus, the present study aims to understand the effects of vitamin D on the prevention and treatment of COVID-19. Methods: A systematic review of the literature was conducted in the PubMed, Cochrane and Scielo databases, based on articles published in 2019 and 2020. Of the 319 articles identified, 7 were selected from observational studies and one clinical trial. Results: Few studies are available to date, and studies have brought controversial results, since observational studies have associated that low vitamin D levels could interfere with the prevention and severity of the disease, but others have not observed associations. Conclusion: There is still no scientific basis for establishing a causal relationship between vitamin D levels and SARS-CoV-2 infection, whether in prevention, treatment or mortality. Therefore, further studies are needed to understand how these factors interact. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-26 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/11174 10.33448/rsd-v9i12.11174 |
url |
https://rsdjournal.org/index.php/rsd/article/view/11174 |
identifier_str_mv |
10.33448/rsd-v9i12.11174 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/11174/9969 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 9 No. 12; e32191211174 Research, Society and Development; Vol. 9 Núm. 12; e32191211174 Research, Society and Development; v. 9 n. 12; e32191211174 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052666692501504 |