Prevalence of cases of autoimmune diseases and primary immunodeficiencies registered in hospitals in Agreste de Pernambuco
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/12681 |
Resumo: | Autoimmune diseases are pathologies where the body itself develops an immune response against an autoantigen (autologous). There are several factors that trigger this loss of tolerance to the organism itself, such as genetic factors. The hereditary risk for most of these pathologies is attributable to multiple loci, the major contribution of which is made by the MHC genes. The objective of this research was to survey diagnosed cases of Autoimmune Diseases (DAIs) and Primary Immunodeficiencies (IP) in cities located in Agreste and in the capital of Pernambuco. In Agreste, four cities were selected for the development of this work. After the approval letter was released, and the ethics and research committee (CEP UNIFAVIP) approved, the research began. 1,000 medical records of patients diagnosed with these pathologies were analyzed between the years 2016 to 2018. Of these, only 94 medical records were used because they contain complete information for the results of this work. 93 records of DAIs and 1 IDP were identified. Even though it was not one of the objectives proposed, initially by the research, numerous difficulties were found both in access and in the interpretation of medical records, such as incomplete data and SID of the diagnosed disease. Celiac disease was the pathology that had the highest prevalence in the harsh Pernambuco. |
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Prevalence of cases of autoimmune diseases and primary immunodeficiencies registered in hospitals in Agreste de PernambucoPrevalencia de casos de enfermedades autoinmunes e inmunodeficiencias primarias registrados en hospitales de Agreste de PernambucoPrevalência de casos de doenças autoimunes e imunodeficiências primárias registradas em hospitais no Agreste de PernambucoAutoantigenoLevantamentoProntuário. AutoantigenSurveyMedical record.AutoantígenoEncuestaHistorial médico.Autoimmune diseases are pathologies where the body itself develops an immune response against an autoantigen (autologous). There are several factors that trigger this loss of tolerance to the organism itself, such as genetic factors. The hereditary risk for most of these pathologies is attributable to multiple loci, the major contribution of which is made by the MHC genes. The objective of this research was to survey diagnosed cases of Autoimmune Diseases (DAIs) and Primary Immunodeficiencies (IP) in cities located in Agreste and in the capital of Pernambuco. In Agreste, four cities were selected for the development of this work. After the approval letter was released, and the ethics and research committee (CEP UNIFAVIP) approved, the research began. 1,000 medical records of patients diagnosed with these pathologies were analyzed between the years 2016 to 2018. Of these, only 94 medical records were used because they contain complete information for the results of this work. 93 records of DAIs and 1 IDP were identified. Even though it was not one of the objectives proposed, initially by the research, numerous difficulties were found both in access and in the interpretation of medical records, such as incomplete data and SID of the diagnosed disease. Celiac disease was the pathology that had the highest prevalence in the harsh Pernambuco.Las enfermedades autoinmunes son patologías en las que el propio organismo desarrolla una respuesta inmunitaria frente a un autoantígeno (autólogo). Son varios los factores que desencadenan esta pérdida de tolerancia al propio organismo, como los factores genéticos. El riesgo hereditario de la mayoría de estas patologías es atribuible a múltiples loci, cuya principal contribución la realizan los genes MHC. El objetivo de esta investigación fue relevar casos diagnosticados de Enfermedades Autoinmunes (IAD) e Inmunodeficiencias Primarias (PI) en ciudades ubicadas en Agreste y en la capital de Pernambuco. En Agreste se seleccionaron cuatro ciudades para el desarrollo de este trabajo. Después de que se publicó la carta de aprobación y el comité de ética e investigación (CEP UNIFAVIP) la aprobó, comenzó la investigación. Se analizaron 1,000 historias clínicas de pacientes diagnosticados con estas patologías entre los años 2016 a 2018. De estas, solo se utilizaron 94 historias clínicas porque contienen información completa para los resultados de este trabajo. Se identificaron 93 registros de DAI y 1 PDI. Si bien no era uno de los objetivos propuestos, inicialmente por la investigación, se encontraron numerosas dificultades tanto en el acceso como en la interpretación de las historias clínicas, como datos incompletos y DIM de la enfermedad diagnosticada. La enfermedad celíaca fue la patología de mayor prevalencia en el agreste Pernambuco.As doenças autoimunes são patológias onde o próprio organismo desenvolve uma resposta imune contra um autoantígeno (autológo). Existem vários fatores que desencadeiam essa perca de tolerância ao próprio organismo, como por exemplo, os genéticos. O risco hereditário para a maioria dessas patológicas é atribuível a múltiplos loci, cuja maior contribuição é feita pelos os genes do MHC. Objetivou-se, com esta pesquisa, fazer levantamento de casos diagnosticados de Doenças Autoimunes (DAIs) e Imunodeficiências Primaria (IP) em cidades localizadas no Agreste e na capital de Pernambuco. No Agreste, foram selecionadas quatro cidades para o desenvolvimento desse trabalho. Após a liberação da carta de anuência, e aprovação do comitê de ética e pesquisa (CEP UNIFAVIP), iniciou a pesquisa. Foram analisados 1 mil prontuários, de pacientes diagnosticados com estas patologias, entre os anos de 2016 a 2018. Desses, apenas 94 prontuários foram utilizados por conterem informações completas para os resultados deste trabalho. Foram identificados 93 registros de DAIs e 1 de IDP. Mesmo não tendo sido um dos objetivos propostos, inicialmente pela pesquisa, foram constatadas inúmeras dificuldades tanto no acesso quanto na interpretação dos prontuários, como por exemplo dados incompletos e SID da doença diagnosticada. A doença celíaca foi a patologia que apresentou maior prevalência no agreste pernambucano.Research, Society and Development2021-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1268110.33448/rsd-v10i2.12681Research, Society and Development; Vol. 10 No. 2; e50410212681Research, Society and Development; Vol. 10 Núm. 2; e50410212681Research, Society and Development; v. 10 n. 2; e504102126812525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/12681/11643Copyright (c) 2021 Michael Gabriel Agustinho Barbosa; Patrícia Alves Genuíno; Emanuela Ingridy Silva; Simone Martis dos Santos; Severina Ridrigues de Oliveira Linshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBarbosa, Michael Gabriel Agustinho Genuíno, Patrícia Alves Silva, Emanuela Ingridy Santos, Simone Martis dosLins, Severina Ridrigues de Oliveira 2021-03-02T09:32:39Zoai:ojs.pkp.sfu.ca:article/12681Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:34:11.670413Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Prevalence of cases of autoimmune diseases and primary immunodeficiencies registered in hospitals in Agreste de Pernambuco Prevalencia de casos de enfermedades autoinmunes e inmunodeficiencias primarias registrados en hospitales de Agreste de Pernambuco Prevalência de casos de doenças autoimunes e imunodeficiências primárias registradas em hospitais no Agreste de Pernambuco |
title |
Prevalence of cases of autoimmune diseases and primary immunodeficiencies registered in hospitals in Agreste de Pernambuco |
spellingShingle |
Prevalence of cases of autoimmune diseases and primary immunodeficiencies registered in hospitals in Agreste de Pernambuco Barbosa, Michael Gabriel Agustinho Autoantigeno Levantamento Prontuário. Autoantigen Survey Medical record. Autoantígeno Encuesta Historial médico. |
title_short |
Prevalence of cases of autoimmune diseases and primary immunodeficiencies registered in hospitals in Agreste de Pernambuco |
title_full |
Prevalence of cases of autoimmune diseases and primary immunodeficiencies registered in hospitals in Agreste de Pernambuco |
title_fullStr |
Prevalence of cases of autoimmune diseases and primary immunodeficiencies registered in hospitals in Agreste de Pernambuco |
title_full_unstemmed |
Prevalence of cases of autoimmune diseases and primary immunodeficiencies registered in hospitals in Agreste de Pernambuco |
title_sort |
Prevalence of cases of autoimmune diseases and primary immunodeficiencies registered in hospitals in Agreste de Pernambuco |
author |
Barbosa, Michael Gabriel Agustinho |
author_facet |
Barbosa, Michael Gabriel Agustinho Genuíno, Patrícia Alves Silva, Emanuela Ingridy Santos, Simone Martis dos Lins, Severina Ridrigues de Oliveira |
author_role |
author |
author2 |
Genuíno, Patrícia Alves Silva, Emanuela Ingridy Santos, Simone Martis dos Lins, Severina Ridrigues de Oliveira |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Barbosa, Michael Gabriel Agustinho Genuíno, Patrícia Alves Silva, Emanuela Ingridy Santos, Simone Martis dos Lins, Severina Ridrigues de Oliveira |
dc.subject.por.fl_str_mv |
Autoantigeno Levantamento Prontuário. Autoantigen Survey Medical record. Autoantígeno Encuesta Historial médico. |
topic |
Autoantigeno Levantamento Prontuário. Autoantigen Survey Medical record. Autoantígeno Encuesta Historial médico. |
description |
Autoimmune diseases are pathologies where the body itself develops an immune response against an autoantigen (autologous). There are several factors that trigger this loss of tolerance to the organism itself, such as genetic factors. The hereditary risk for most of these pathologies is attributable to multiple loci, the major contribution of which is made by the MHC genes. The objective of this research was to survey diagnosed cases of Autoimmune Diseases (DAIs) and Primary Immunodeficiencies (IP) in cities located in Agreste and in the capital of Pernambuco. In Agreste, four cities were selected for the development of this work. After the approval letter was released, and the ethics and research committee (CEP UNIFAVIP) approved, the research began. 1,000 medical records of patients diagnosed with these pathologies were analyzed between the years 2016 to 2018. Of these, only 94 medical records were used because they contain complete information for the results of this work. 93 records of DAIs and 1 IDP were identified. Even though it was not one of the objectives proposed, initially by the research, numerous difficulties were found both in access and in the interpretation of medical records, such as incomplete data and SID of the diagnosed disease. Celiac disease was the pathology that had the highest prevalence in the harsh Pernambuco. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/12681 10.33448/rsd-v10i2.12681 |
url |
https://rsdjournal.org/index.php/rsd/article/view/12681 |
identifier_str_mv |
10.33448/rsd-v10i2.12681 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/12681/11643 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 2; e50410212681 Research, Society and Development; Vol. 10 Núm. 2; e50410212681 Research, Society and Development; v. 10 n. 2; e50410212681 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052783898132480 |