Coexistence of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 in polymicrobial bloodstream isolates from a patient with acute myeloid leukemia

Detalhes bibliográficos
Autor(a) principal: Soares, Cynthia Regina Pedrosa
Data de Publicação: 2021
Outros Autores: Magalhães, Vera, Araújo, Paulo Sérgio Ramos de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/14985
Resumo: Background: Bloodstream infections are among the most frequent and serious complications in patients with haematological malignancies. Case presentation: A patient diagnosed with acute myeloid leukemia was admitted to the hospital for chemotherapy induction, developed several episodes of febrile neutropenia. Had bloodstream infection with at least four strains of Gram-negative bacteria, including Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumanii. The majority showed resistance to ampicillin, cefepime, ceftriaxone, ciprofloxacin and sulfamethoxazole/trimethoprim. blaTEM and blaSIM were detected in P. aeruginosa, blaTEM, blaCTX and blaOXA-48 in E. coli, blaCTX, blaKPC, blaNDM, blaSIM and blaOXA-48 in K. pneumoniae and blaOXA-48 in A. baumannii. Conclusions: The patient was treated with meropenem for 10 days, without progressing from fever episodes, evolved to death.
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spelling Coexistence of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 in polymicrobial bloodstream isolates from a patient with acute myeloid leukemia Coexistencia de blaTEM, blaCTX, blaKPC, blaNDM, blaSIM y blaOXA-48 en aislados polimicrobianos del torrente sanguíneo de un paciente con leucemia mieloide agudaCoexistência de of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 em isolados polimicrobianos da corrente sanguínea de um paciente com leucemia mieloide agudaPolymicrobial infectionβ-LactamaseHematological malignancyCarbapenemasesBloodstream infection.Infección polimicrobianaβ-lactamasaMalignidad hematológicaCarbapenemasasInfección del torrente sanguíneo.Infecção polimicrobianaβ-LactamaseMalignidade hematológicaCarbapenemasesInfecção da corrente sanguínea.Background: Bloodstream infections are among the most frequent and serious complications in patients with haematological malignancies. Case presentation: A patient diagnosed with acute myeloid leukemia was admitted to the hospital for chemotherapy induction, developed several episodes of febrile neutropenia. Had bloodstream infection with at least four strains of Gram-negative bacteria, including Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumanii. The majority showed resistance to ampicillin, cefepime, ceftriaxone, ciprofloxacin and sulfamethoxazole/trimethoprim. blaTEM and blaSIM were detected in P. aeruginosa, blaTEM, blaCTX and blaOXA-48 in E. coli, blaCTX, blaKPC, blaNDM, blaSIM and blaOXA-48 in K. pneumoniae and blaOXA-48 in A. baumannii. Conclusions: The patient was treated with meropenem for 10 days, without progressing from fever episodes, evolved to death.Antecedentes: las infecciones del torrente sanguíneo se encuentran entre las complicaciones más frecuentes y graves en pacientes con neoplasias hematológicas. Presentación del caso: Un paciente diagnosticado con leucemia mieloide aguda fue ingresado en el hospital para inducción de quimioterapia, desarrolló varios episodios de neutropenia febril. Tenía una infección del torrente sanguíneo con al menos cuatro cepas de bacterias gramnegativas, incluidas Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae y Acinetobacter baumanii. La mayoría mostró resistencia a ampicilina, cefepima, ceftriaxona, ciprofloxacina y sulfametoxazol / trimetoprima. blaTEM y blaSIM se detectaron en P. aeruginosa, blaTEM, blaCTX y blaOXA-48 en E. coli, blaCTX, blaKPC, blaNDM, blaSIM y blaOXA-48 en K. pneumoniae y blaOXA-48 en A. baumannii. Conclusiones: El paciente fue tratado con meropenem durante 10 días, sin progresar de episodios febriles, evolucionó hasta la muerte.Introdução: As infecções da corrente sanguínea estão entre as complicações mais frequentes e graves em pacientes com doenças hematológicas malignas. Apresentação do caso: Um paciente com diagnóstico de leucemia mielóide aguda foi admitido no hospital para indução de quimioterapia, desenvolveu vários episódios de neutropenia febril. Teve infecção da corrente sanguínea com pelo menos quatro cepas de bactérias Gram-negativas, incluindo Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae e Acinetobacter baumanii. A maioria mostrou resistência a ampicilina, cefepima, ceftriaxona, ciprofloxacina e sulfametoxazol/trimetoprima. blaTEM e blaSIM foram detectados em P. aeruginosa, blaTEM, blaCTX e blaOXA-48 em E. coli, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 em K. pneumoniae e blaOXA-48 em A. baumannii. Conclusões: O paciente foi tratado com meropenem por 10 dias, sem evolução de episódios febris, evoluindo a óbito.Research, Society and Development2021-05-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1498510.33448/rsd-v10i5.14985Research, Society and Development; Vol. 10 No. 5; e39310514985Research, Society and Development; Vol. 10 Núm. 5; e39310514985Research, Society and Development; v. 10 n. 5; e393105149852525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/14985/13513Copyright (c) 2021 Cynthia Regina Pedrosa Soares; Vera Magalhães; Paulo Sérgio Ramos de Araújohttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSoares, Cynthia Regina Pedrosa Magalhães, VeraAraújo, Paulo Sérgio Ramos de 2021-05-17T18:20:49Zoai:ojs.pkp.sfu.ca:article/14985Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:35:55.424206Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Coexistence of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 in polymicrobial bloodstream isolates from a patient with acute myeloid leukemia
Coexistencia de blaTEM, blaCTX, blaKPC, blaNDM, blaSIM y blaOXA-48 en aislados polimicrobianos del torrente sanguíneo de un paciente con leucemia mieloide aguda
Coexistência de of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 em isolados polimicrobianos da corrente sanguínea de um paciente com leucemia mieloide aguda
title Coexistence of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 in polymicrobial bloodstream isolates from a patient with acute myeloid leukemia
spellingShingle Coexistence of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 in polymicrobial bloodstream isolates from a patient with acute myeloid leukemia
Soares, Cynthia Regina Pedrosa
Polymicrobial infection
β-Lactamase
Hematological malignancy
Carbapenemases
Bloodstream infection.
Infección polimicrobiana
β-lactamasa
Malignidad hematológica
Carbapenemasas
Infección del torrente sanguíneo.
Infecção polimicrobiana
β-Lactamase
Malignidade hematológica
Carbapenemases
Infecção da corrente sanguínea.
title_short Coexistence of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 in polymicrobial bloodstream isolates from a patient with acute myeloid leukemia
title_full Coexistence of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 in polymicrobial bloodstream isolates from a patient with acute myeloid leukemia
title_fullStr Coexistence of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 in polymicrobial bloodstream isolates from a patient with acute myeloid leukemia
title_full_unstemmed Coexistence of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 in polymicrobial bloodstream isolates from a patient with acute myeloid leukemia
title_sort Coexistence of blaTEM, blaCTX, blaKPC, blaNDM, blaSIM e blaOXA-48 in polymicrobial bloodstream isolates from a patient with acute myeloid leukemia
author Soares, Cynthia Regina Pedrosa
author_facet Soares, Cynthia Regina Pedrosa
Magalhães, Vera
Araújo, Paulo Sérgio Ramos de
author_role author
author2 Magalhães, Vera
Araújo, Paulo Sérgio Ramos de
author2_role author
author
dc.contributor.author.fl_str_mv Soares, Cynthia Regina Pedrosa
Magalhães, Vera
Araújo, Paulo Sérgio Ramos de
dc.subject.por.fl_str_mv Polymicrobial infection
β-Lactamase
Hematological malignancy
Carbapenemases
Bloodstream infection.
Infección polimicrobiana
β-lactamasa
Malignidad hematológica
Carbapenemasas
Infección del torrente sanguíneo.
Infecção polimicrobiana
β-Lactamase
Malignidade hematológica
Carbapenemases
Infecção da corrente sanguínea.
topic Polymicrobial infection
β-Lactamase
Hematological malignancy
Carbapenemases
Bloodstream infection.
Infección polimicrobiana
β-lactamasa
Malignidad hematológica
Carbapenemasas
Infección del torrente sanguíneo.
Infecção polimicrobiana
β-Lactamase
Malignidade hematológica
Carbapenemases
Infecção da corrente sanguínea.
description Background: Bloodstream infections are among the most frequent and serious complications in patients with haematological malignancies. Case presentation: A patient diagnosed with acute myeloid leukemia was admitted to the hospital for chemotherapy induction, developed several episodes of febrile neutropenia. Had bloodstream infection with at least four strains of Gram-negative bacteria, including Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumanii. The majority showed resistance to ampicillin, cefepime, ceftriaxone, ciprofloxacin and sulfamethoxazole/trimethoprim. blaTEM and blaSIM were detected in P. aeruginosa, blaTEM, blaCTX and blaOXA-48 in E. coli, blaCTX, blaKPC, blaNDM, blaSIM and blaOXA-48 in K. pneumoniae and blaOXA-48 in A. baumannii. Conclusions: The patient was treated with meropenem for 10 days, without progressing from fever episodes, evolved to death.
publishDate 2021
dc.date.none.fl_str_mv 2021-05-10
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/14985
10.33448/rsd-v10i5.14985
url https://rsdjournal.org/index.php/rsd/article/view/14985
identifier_str_mv 10.33448/rsd-v10i5.14985
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/14985/13513
dc.rights.driver.fl_str_mv Copyright (c) 2021 Cynthia Regina Pedrosa Soares; Vera Magalhães; Paulo Sérgio Ramos de Araújo
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2021 Cynthia Regina Pedrosa Soares; Vera Magalhães; Paulo Sérgio Ramos de Araújo
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 5; e39310514985
Research, Society and Development; Vol. 10 Núm. 5; e39310514985
Research, Society and Development; v. 10 n. 5; e39310514985
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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