Evaluation of the influence of periodontal disease on serum levels of C-reactive protein
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/5310 |
Resumo: | Objective: To investigate the influence of periodontal disease on serum levels of C-reactive protein (CRP), evaluating the levels of this biomolecule in patients with and without periodontal disease and, in those who have periodontal disease, evaluating the levels of this protein before and after periodontal treatment. Methodology: The research was carried out with 82 patients seen at the Clinic-School of Dentistry of the Federal University of Campina Grande, campus Patos-PB. The individuals were divided into two groups, one consisting of 42 patients with healthy periodontium and the other composed of 40 patients with periodontal disease. Among the individuals in the group with periodontal disease, 11 were reassessed one week after the completion of periodontal treatment. Results: CRP concentrations were significantly higher in the group with periodontal disease (6.09 ± 1.34 mg / l, n = 40) compared to the control group (2.93 ± 0.55 mg / l, n = 42). The results also showed that periodontal treatment reduced CRP values (3.76 ± 0.92 mg / l, n = 11) when compared to values before treatment (10.58 ± 3.69 mg / l, n = 11), however, with no statistically significant difference. Conclusion: It is observed that CRP levels are significantly increased in the serum of patients with periodontal disease compared to patients with healthy periodontium and that lower CRP levels were observed after non-surgical periodontal therapy. The results indicate that periodontal disease interferes with serum CRP levels, and that periodontal treatment can have a positive effect in reducing this protein. |
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Evaluation of the influence of periodontal disease on serum levels of C-reactive proteinEvaluación de la influencia de la enfermedad periodontal en los niveles del suero de proteína CreactivaAvaliação da influência da doença periodontal sobre os níveis séricos de proteína C reativaDoenças periodontaisMediadores da inflamaçãoTerapêutica.Enfermedades periodontalesMediadores de inflamaciónTerapéutica.Periodontal diseasesInflammation mediatorsTherapeutics.Objective: To investigate the influence of periodontal disease on serum levels of C-reactive protein (CRP), evaluating the levels of this biomolecule in patients with and without periodontal disease and, in those who have periodontal disease, evaluating the levels of this protein before and after periodontal treatment. Methodology: The research was carried out with 82 patients seen at the Clinic-School of Dentistry of the Federal University of Campina Grande, campus Patos-PB. The individuals were divided into two groups, one consisting of 42 patients with healthy periodontium and the other composed of 40 patients with periodontal disease. Among the individuals in the group with periodontal disease, 11 were reassessed one week after the completion of periodontal treatment. Results: CRP concentrations were significantly higher in the group with periodontal disease (6.09 ± 1.34 mg / l, n = 40) compared to the control group (2.93 ± 0.55 mg / l, n = 42). The results also showed that periodontal treatment reduced CRP values (3.76 ± 0.92 mg / l, n = 11) when compared to values before treatment (10.58 ± 3.69 mg / l, n = 11), however, with no statistically significant difference. Conclusion: It is observed that CRP levels are significantly increased in the serum of patients with periodontal disease compared to patients with healthy periodontium and that lower CRP levels were observed after non-surgical periodontal therapy. The results indicate that periodontal disease interferes with serum CRP levels, and that periodontal treatment can have a positive effect in reducing this protein.Objetivo: Investigar la influencia de la enfermedad periodontal en los niveles séricos de proteína C reactiva (PCR), evaluando los niveles de esta biomolécula en pacientes con y sin enfermedad periodontal y, en aquellos que tienen enfermedad periodontal, evaluando los niveles de esta proteína antes y después del tratamiento periodontal. Metodología: La investigación se realizó con 82 pacientes atendidos en la Clínica-Escuela de Odontología de la Universidad Federal de Campina Grande, campus Patos-PB. Los individuos se dividieron en dos grupos, uno compuesto por 42 pacientes con periodonto sano y el otro compuesto por 40 pacientes con enfermedad periodontal. Entre los individuos del grupo con enfermedad periodontal, 11 fueron reevaluados una semana después de la finalización del tratamiento periodontal. Resultados: Las concentraciones de PCR fueron significativamente más altas en el grupo con enfermedad periodontal (6.09 ± 1.34 mg / l, n = 40) en comparación con el grupo control (2.93 ± 0.55 mg / l, n = 42). Los resultados también mostraron que el tratamiento periodontal redujo los valores de PCR (3.76 ± 0.92 mg / l, n = 11) en comparación con los valores antes del tratamiento (10.58 ± 3.69 mg / l, n = 11), sin embargo, sin diferencia estadísticamente significativa. Conclusión: Se observa que los niveles de PCR aumentan significativamente en el suero de pacientes con enfermedad periodontal en comparación con pacientes con periodontio sano y que se observaron niveles más bajos de PCR después de la terapia periodontal no quirúrgica. Los resultados indican que la enfermedad periodontal interfiere con los niveles séricos de PCR y que el tratamiento periodontal puede tener un efecto positivo en la reducción de esta proteína.Objetivo: Investigar a influência da doença periodontal sobre os níveis séricos de proteína C reativa (PCR), avaliando-se os níveis desta biomolécula em pacientes com e sem doença periodontal e, naqueles que apresentam a doença periodontal, avaliando os níveis dessa proteína antes e após o tratamento periodontal. Metodologia: A pesquisa foi realizada com 82 pacientes atendidos da Clínica-Escola de Odontologia da Universidade Federal de Campina Grande, campus Patos-PB. Os indivíduos foram divididos em dois grupos, sendo um constituído por 42 pacientes com periodonto saudável e o outro composto por 40 pacientes com doença periodontal. Dentre os indivíduos do grupo com doença periodontal, 11 foram reavaliados uma semana após a conclusão do tratamento periodontal. Resultados: As concentrações de PCR foram significantemente maiores no grupo com a doença periodontal (6,09 ± 1,34 mg/l, n = 40) em relação ao grupo controle (2,93 ± 0,55 mg/l, n = 42). Os resultados mostraram ainda que o tratamento periodontal reduziu os valores de PCR (3,76 ± 0,92 mg/l, n = 11) quando comparados aos valores antes do tratamento (10,58 ± 3,69 mg/l, n = 11), entretanto, sem diferença estatisticamente significante. Conclusão: Observa-se que os níveis de PCR se encontram significantemente aumentados no soro dos pacientes com doença periodontal em relação aos pacientes com periodonto saudável e que níveis mais baixos de PCR foram observados após a terapia periodontal não cirúrgica. Os resultados indicam que a doença periodontal interfere nos níveis séricos de PCR, e que o tratamento periodontal pode ter efeito positivo na redução dessa proteína.Research, Society and Development2020-06-19info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/531010.33448/rsd-v9i8.5310Research, Society and Development; Vol. 9 No. 8; e04985310Research, Society and Development; Vol. 9 Núm. 8; e04985310Research, Society and Development; v. 9 n. 8; e049853102525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/5310/4333Copyright (c) 2020 Sérvulo da Costa Rodrigues-Neto, Emmanuel Nunes de Oliveira, Byanca Andrade Martins, Ismael Lima Silva, Alessandro Marques De Souza-Junior, Roberto de Lucena Jeronimo, João Nilton Lopes de Sousa, Maria Angélica Sátyro Gomes Alvesinfo:eu-repo/semantics/openAccessRodrigues-Neto, Sérvulo da CostaOliveira, Emmanuel Nunes deMartins, Byanca AndradeSilva, Ismael LimaSouza Júnior, Alessandro Marques deJerônimo, Roberto de LucenaSousa, João Nilton Lopes deAlves, Maria Angélica Sátyro Gomes2020-08-20T18:00:17Zoai:ojs.pkp.sfu.ca:article/5310Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:28:51.873269Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Evaluation of the influence of periodontal disease on serum levels of C-reactive protein Evaluación de la influencia de la enfermedad periodontal en los niveles del suero de proteína Creactiva Avaliação da influência da doença periodontal sobre os níveis séricos de proteína C reativa |
title |
Evaluation of the influence of periodontal disease on serum levels of C-reactive protein |
spellingShingle |
Evaluation of the influence of periodontal disease on serum levels of C-reactive protein Rodrigues-Neto, Sérvulo da Costa Doenças periodontais Mediadores da inflamação Terapêutica. Enfermedades periodontales Mediadores de inflamación Terapéutica. Periodontal diseases Inflammation mediators Therapeutics. |
title_short |
Evaluation of the influence of periodontal disease on serum levels of C-reactive protein |
title_full |
Evaluation of the influence of periodontal disease on serum levels of C-reactive protein |
title_fullStr |
Evaluation of the influence of periodontal disease on serum levels of C-reactive protein |
title_full_unstemmed |
Evaluation of the influence of periodontal disease on serum levels of C-reactive protein |
title_sort |
Evaluation of the influence of periodontal disease on serum levels of C-reactive protein |
author |
Rodrigues-Neto, Sérvulo da Costa |
author_facet |
Rodrigues-Neto, Sérvulo da Costa Oliveira, Emmanuel Nunes de Martins, Byanca Andrade Silva, Ismael Lima Souza Júnior, Alessandro Marques de Jerônimo, Roberto de Lucena Sousa, João Nilton Lopes de Alves, Maria Angélica Sátyro Gomes |
author_role |
author |
author2 |
Oliveira, Emmanuel Nunes de Martins, Byanca Andrade Silva, Ismael Lima Souza Júnior, Alessandro Marques de Jerônimo, Roberto de Lucena Sousa, João Nilton Lopes de Alves, Maria Angélica Sátyro Gomes |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Rodrigues-Neto, Sérvulo da Costa Oliveira, Emmanuel Nunes de Martins, Byanca Andrade Silva, Ismael Lima Souza Júnior, Alessandro Marques de Jerônimo, Roberto de Lucena Sousa, João Nilton Lopes de Alves, Maria Angélica Sátyro Gomes |
dc.subject.por.fl_str_mv |
Doenças periodontais Mediadores da inflamação Terapêutica. Enfermedades periodontales Mediadores de inflamación Terapéutica. Periodontal diseases Inflammation mediators Therapeutics. |
topic |
Doenças periodontais Mediadores da inflamação Terapêutica. Enfermedades periodontales Mediadores de inflamación Terapéutica. Periodontal diseases Inflammation mediators Therapeutics. |
description |
Objective: To investigate the influence of periodontal disease on serum levels of C-reactive protein (CRP), evaluating the levels of this biomolecule in patients with and without periodontal disease and, in those who have periodontal disease, evaluating the levels of this protein before and after periodontal treatment. Methodology: The research was carried out with 82 patients seen at the Clinic-School of Dentistry of the Federal University of Campina Grande, campus Patos-PB. The individuals were divided into two groups, one consisting of 42 patients with healthy periodontium and the other composed of 40 patients with periodontal disease. Among the individuals in the group with periodontal disease, 11 were reassessed one week after the completion of periodontal treatment. Results: CRP concentrations were significantly higher in the group with periodontal disease (6.09 ± 1.34 mg / l, n = 40) compared to the control group (2.93 ± 0.55 mg / l, n = 42). The results also showed that periodontal treatment reduced CRP values (3.76 ± 0.92 mg / l, n = 11) when compared to values before treatment (10.58 ± 3.69 mg / l, n = 11), however, with no statistically significant difference. Conclusion: It is observed that CRP levels are significantly increased in the serum of patients with periodontal disease compared to patients with healthy periodontium and that lower CRP levels were observed after non-surgical periodontal therapy. The results indicate that periodontal disease interferes with serum CRP levels, and that periodontal treatment can have a positive effect in reducing this protein. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-06-19 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/5310 10.33448/rsd-v9i8.5310 |
url |
https://rsdjournal.org/index.php/rsd/article/view/5310 |
identifier_str_mv |
10.33448/rsd-v9i8.5310 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/5310/4333 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 9 No. 8; e04985310 Research, Society and Development; Vol. 9 Núm. 8; e04985310 Research, Society and Development; v. 9 n. 8; e04985310 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052737040416768 |