High-protein diet and changes in kidney function: an integrative literature review

• Autor(a) principal: Marques, João Pedro Fernandes
• Data de Publicação: 2022
• Outros Autores: Silva, Arthur Anderson, Almeida, Kelly Vargas Londe Ribeiro de
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/38623
• topic: Rim; Dieta rica em proteínas; Doença Renal Crônica.; Riñón; Dieta rica en proteínas; Enfermedad Renal Crónica.; Kidney; High-protein diet; Chronic Kidney Disease.

Introduction: Hyperproteic diets have become increasingly common in today's society and can be defined by protein intake above 0.8 to 1 g/Kg/day. There is a strong connection between protein intake and the worsening of chronic kidney disease (CKD), which can be characterized by an estimated glomerular filtration rate (eGFR) below 60 mL/min/1.73 m². Objective: Therefore, this article seeks to elucidate the effects that following a high-protein diet has on kidney function. Methodology: The present study consists of an integrative literature review on the evaluation of a high-protein diet for kidney health, based on articles written in English published in the last 4 years, 2018 to 2022, in the following databases: Virtual Library of Health (BVS); National Library of Medicine (PubMed MEDLINE), Scientific Electronic Library Online (SCIELO), EbscoHost. Results and discussion: Among the results found, there is agreement about glomerular hyperfiltration, but disagreements about the mechanism by which it occurs, and the potential harmful effects to the kidney health caused by it, and there are also disagreements about the role of the proteins in the formation of kidney stones. However, there is a decrease in mortality in the population with regular renal function in consumption of high amounts of protein, and also in the mortality of ICU patients following high-protein diets. Final considerations: Randomized controlled clinical studies are needed to evaluate a direct comparison between the alterations caused by high and low protein intake.