Therapeutic options for the treatment of multiple sclerosis

Detalhes bibliográficos
Autor(a) principal: Nery, Lara Gomes
Data de Publicação: 2022
Outros Autores: Costa, Ana Cláudia Maia Mendonça da, Ribeiro, Gabriela Ramos, Oliveira, Gustavo Silva, Vaz, Rodolfo Lopes, Arruda, Jalsi Tacon
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/26331
Resumo: Multiple Sclerosis (MS) is a chronic degenerative disease that affects the central nervous system. Treatment is aimed at reducing the inflammatory process and delaying the progression of the disease. This work analyzes the existing and currently available therapeutic options for the treatment of patients with multiple sclerosis. An epidemiological study was carried out, based on an integrative review of data available in PubMed, SciELO and Google Scholar, using the descriptors “multiple sclerosis” and “treatment”. Pharmacological therapy for MS can be used for symptomatic treatment, for acute episodes/outbreaks, or for the use of disease-modifying drugs. The existing variety of disease-modifying drugs allows flexibility in choosing the best option according to each patient's profile. In addition to drug treatments, complementary therapies are important for neurorehabilitation and symptom control, such as psychology, speech therapy, neuropsychology, physical therapy and occupational therapy. Other points recently discussed in the treatment of MS are the supplementary use of vitamin D, the use of cannabinoid compounds, and a future perspective of autologous stem cell transplantation. Considering the prevalence and impact of MS on the long-term quality of life of patients, the importance of early diagnosis and initiation of treatment, as well as the search for new evidence for the best possible therapeutic management of MS are fundamental for quality of life. of the patient.
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spelling Therapeutic options for the treatment of multiple sclerosisOpciones terapéuticas para el tratamiento de la esclerosis múltipleOpções terapêuticas para o tratamento da esclerose múltiplaEsclerose DisseminadaTerapêuticaTerapias complementares.Esclerosis diseminadaTerapiaTerapias complementarias.Disseminated sclerosisTherapyComplementary therapies.Multiple Sclerosis (MS) is a chronic degenerative disease that affects the central nervous system. Treatment is aimed at reducing the inflammatory process and delaying the progression of the disease. This work analyzes the existing and currently available therapeutic options for the treatment of patients with multiple sclerosis. An epidemiological study was carried out, based on an integrative review of data available in PubMed, SciELO and Google Scholar, using the descriptors “multiple sclerosis” and “treatment”. Pharmacological therapy for MS can be used for symptomatic treatment, for acute episodes/outbreaks, or for the use of disease-modifying drugs. The existing variety of disease-modifying drugs allows flexibility in choosing the best option according to each patient's profile. In addition to drug treatments, complementary therapies are important for neurorehabilitation and symptom control, such as psychology, speech therapy, neuropsychology, physical therapy and occupational therapy. Other points recently discussed in the treatment of MS are the supplementary use of vitamin D, the use of cannabinoid compounds, and a future perspective of autologous stem cell transplantation. Considering the prevalence and impact of MS on the long-term quality of life of patients, the importance of early diagnosis and initiation of treatment, as well as the search for new evidence for the best possible therapeutic management of MS are fundamental for quality of life. of the patient.La Esclerosis Múltiple (EM) es una enfermedad crónico-degenerativa que afecta al sistema nervioso central. El tratamiento está dirigido a reducir el proceso inflamatorio y retrasar la progresión de la enfermedad. Este trabajo analiza las opciones terapéuticas existentes y actualmente disponibles para el tratamiento de pacientes con esclerosis múltiple. Se realizó un estudio epidemiológico, basado en una revisión integradora de datos disponibles en PubMed, SciELO y Google Scholar, utilizando los descriptores “esclerosis múltiple” y “tratamiento”. La terapia farmacológica para la EM se puede utilizar para el tratamiento sintomático, para episodios/brotes agudos o para el uso de fármacos modificadores de la enfermedad. La variedad existente de fármacos modificadores de la enfermedad permite flexibilidad en la elección de la mejor opción según el perfil de cada paciente. Además de los tratamientos farmacológicos, son importantes las terapias complementarias para la neurorrehabilitación y el control de los síntomas, como la psicología, la logopedia, la neuropsicología, la fisioterapia y la terapia ocupacional. Otros puntos discutidos recientemente en el tratamiento de la EM son el uso complementario de vitamina D, el uso de compuestos cannabinoides y una perspectiva futura del trasplante autólogo de células madre. Considerando la prevalencia y el impacto de la EM en la calidad de vida a largo plazo de los pacientes, la importancia del diagnóstico temprano y el inicio del tratamiento, así como la búsqueda de nueva evidencia para el mejor manejo terapéutico posible de la EM son fundamentales para la calidad de vida del paciente.A Esclerose Múltipla (EM) é uma doença crônica degenerativa que atinge o sistema nervoso central. O tratamento visa a diminuição do processo inflamatório e retardar o avanço da doença. Este trabalho analisa as opções terapêuticas existentes e atualmente disponíveis para o tratamento de pacientes com esclerose múltipla. Foi realizado um estudo epidemiológico, a partir de uma revisão integrativa dos dados disponíveis no PubMed, SciELO e Google Acadêmico, utilizando os descritores “esclerose múltipla” e “tratamento”. A terapia farmacológica para EM pode ser empregada para tratamento sintomático, de episódios agudos/surtos, ou pela utilização de medicamentos modificadores da doença. A variedade existente de medicamentos modificadores da doença permite flexibilidade na escolha da melhor opção de acordo com o perfil de cada paciente. Aliando-se aos tratamentos medicamentosos, terapias complementares são importantes para a neuroreabilitação e controle de sintomas, como a psicologia, fonoaudiologia, neuropsicologia, fisioterapia e terapia ocupacional. Outros pontos recentemente discutidos no tratamento da EM são a utilização complementar de vitamina D, o uso de compostos canabinoides, e uma perspectiva futura do transplante autólogo de células tronco. Considerando a prevalência e impacto da EM sobre a qualidade de vida dos pacientes a longo prazo, a importância do diagnóstico e início do tratamento precoce, bem como a busca por novas evidências para o melhor manejo terapêutico possível da EM são fundamentais para a qualidade de vida do paciente.Research, Society and Development2022-03-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2633110.33448/rsd-v11i4.26331Research, Society and Development; Vol. 11 No. 4; e7811426331Research, Society and Development; Vol. 11 Núm. 4; e7811426331Research, Society and Development; v. 11 n. 4; e78114263312525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/26331/23683Copyright (c) 2022 Lara Gomes Nery; Ana Cláudia Maia Mendonça da Costa; Gabriela Ramos Ribeiro; Gustavo Silva Oliveira; Rodolfo Lopes Vaz; Jalsi Tacon Arrudahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessNery, Lara Gomes Costa, Ana Cláudia Maia Mendonça daRibeiro, Gabriela Ramos Oliveira, Gustavo Silva Vaz, Rodolfo Lopes Arruda, Jalsi Tacon2022-03-27T17:17:09Zoai:ojs.pkp.sfu.ca:article/26331Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:23.958231Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Therapeutic options for the treatment of multiple sclerosis
Opciones terapéuticas para el tratamiento de la esclerosis múltiple
Opções terapêuticas para o tratamento da esclerose múltipla
title Therapeutic options for the treatment of multiple sclerosis
spellingShingle Therapeutic options for the treatment of multiple sclerosis
Nery, Lara Gomes
Esclerose Disseminada
Terapêutica
Terapias complementares.
Esclerosis diseminada
Terapia
Terapias complementarias.
Disseminated sclerosis
Therapy
Complementary therapies.
title_short Therapeutic options for the treatment of multiple sclerosis
title_full Therapeutic options for the treatment of multiple sclerosis
title_fullStr Therapeutic options for the treatment of multiple sclerosis
title_full_unstemmed Therapeutic options for the treatment of multiple sclerosis
title_sort Therapeutic options for the treatment of multiple sclerosis
author Nery, Lara Gomes
author_facet Nery, Lara Gomes
Costa, Ana Cláudia Maia Mendonça da
Ribeiro, Gabriela Ramos
Oliveira, Gustavo Silva
Vaz, Rodolfo Lopes
Arruda, Jalsi Tacon
author_role author
author2 Costa, Ana Cláudia Maia Mendonça da
Ribeiro, Gabriela Ramos
Oliveira, Gustavo Silva
Vaz, Rodolfo Lopes
Arruda, Jalsi Tacon
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Nery, Lara Gomes
Costa, Ana Cláudia Maia Mendonça da
Ribeiro, Gabriela Ramos
Oliveira, Gustavo Silva
Vaz, Rodolfo Lopes
Arruda, Jalsi Tacon
dc.subject.por.fl_str_mv Esclerose Disseminada
Terapêutica
Terapias complementares.
Esclerosis diseminada
Terapia
Terapias complementarias.
Disseminated sclerosis
Therapy
Complementary therapies.
topic Esclerose Disseminada
Terapêutica
Terapias complementares.
Esclerosis diseminada
Terapia
Terapias complementarias.
Disseminated sclerosis
Therapy
Complementary therapies.
description Multiple Sclerosis (MS) is a chronic degenerative disease that affects the central nervous system. Treatment is aimed at reducing the inflammatory process and delaying the progression of the disease. This work analyzes the existing and currently available therapeutic options for the treatment of patients with multiple sclerosis. An epidemiological study was carried out, based on an integrative review of data available in PubMed, SciELO and Google Scholar, using the descriptors “multiple sclerosis” and “treatment”. Pharmacological therapy for MS can be used for symptomatic treatment, for acute episodes/outbreaks, or for the use of disease-modifying drugs. The existing variety of disease-modifying drugs allows flexibility in choosing the best option according to each patient's profile. In addition to drug treatments, complementary therapies are important for neurorehabilitation and symptom control, such as psychology, speech therapy, neuropsychology, physical therapy and occupational therapy. Other points recently discussed in the treatment of MS are the supplementary use of vitamin D, the use of cannabinoid compounds, and a future perspective of autologous stem cell transplantation. Considering the prevalence and impact of MS on the long-term quality of life of patients, the importance of early diagnosis and initiation of treatment, as well as the search for new evidence for the best possible therapeutic management of MS are fundamental for quality of life. of the patient.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-11
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/26331
10.33448/rsd-v11i4.26331
url https://rsdjournal.org/index.php/rsd/article/view/26331
identifier_str_mv 10.33448/rsd-v11i4.26331
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/26331/23683
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
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dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 4; e7811426331
Research, Society and Development; Vol. 11 Núm. 4; e7811426331
Research, Society and Development; v. 11 n. 4; e7811426331
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
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instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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