Therapeutic options for the treatment of multiple sclerosis
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/26331 |
Resumo: | Multiple Sclerosis (MS) is a chronic degenerative disease that affects the central nervous system. Treatment is aimed at reducing the inflammatory process and delaying the progression of the disease. This work analyzes the existing and currently available therapeutic options for the treatment of patients with multiple sclerosis. An epidemiological study was carried out, based on an integrative review of data available in PubMed, SciELO and Google Scholar, using the descriptors “multiple sclerosis” and “treatment”. Pharmacological therapy for MS can be used for symptomatic treatment, for acute episodes/outbreaks, or for the use of disease-modifying drugs. The existing variety of disease-modifying drugs allows flexibility in choosing the best option according to each patient's profile. In addition to drug treatments, complementary therapies are important for neurorehabilitation and symptom control, such as psychology, speech therapy, neuropsychology, physical therapy and occupational therapy. Other points recently discussed in the treatment of MS are the supplementary use of vitamin D, the use of cannabinoid compounds, and a future perspective of autologous stem cell transplantation. Considering the prevalence and impact of MS on the long-term quality of life of patients, the importance of early diagnosis and initiation of treatment, as well as the search for new evidence for the best possible therapeutic management of MS are fundamental for quality of life. of the patient. |
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Therapeutic options for the treatment of multiple sclerosisOpciones terapéuticas para el tratamiento de la esclerosis múltipleOpções terapêuticas para o tratamento da esclerose múltiplaEsclerose DisseminadaTerapêuticaTerapias complementares.Esclerosis diseminadaTerapiaTerapias complementarias.Disseminated sclerosisTherapyComplementary therapies.Multiple Sclerosis (MS) is a chronic degenerative disease that affects the central nervous system. Treatment is aimed at reducing the inflammatory process and delaying the progression of the disease. This work analyzes the existing and currently available therapeutic options for the treatment of patients with multiple sclerosis. An epidemiological study was carried out, based on an integrative review of data available in PubMed, SciELO and Google Scholar, using the descriptors “multiple sclerosis” and “treatment”. Pharmacological therapy for MS can be used for symptomatic treatment, for acute episodes/outbreaks, or for the use of disease-modifying drugs. The existing variety of disease-modifying drugs allows flexibility in choosing the best option according to each patient's profile. In addition to drug treatments, complementary therapies are important for neurorehabilitation and symptom control, such as psychology, speech therapy, neuropsychology, physical therapy and occupational therapy. Other points recently discussed in the treatment of MS are the supplementary use of vitamin D, the use of cannabinoid compounds, and a future perspective of autologous stem cell transplantation. Considering the prevalence and impact of MS on the long-term quality of life of patients, the importance of early diagnosis and initiation of treatment, as well as the search for new evidence for the best possible therapeutic management of MS are fundamental for quality of life. of the patient.La Esclerosis Múltiple (EM) es una enfermedad crónico-degenerativa que afecta al sistema nervioso central. El tratamiento está dirigido a reducir el proceso inflamatorio y retrasar la progresión de la enfermedad. Este trabajo analiza las opciones terapéuticas existentes y actualmente disponibles para el tratamiento de pacientes con esclerosis múltiple. Se realizó un estudio epidemiológico, basado en una revisión integradora de datos disponibles en PubMed, SciELO y Google Scholar, utilizando los descriptores “esclerosis múltiple” y “tratamiento”. La terapia farmacológica para la EM se puede utilizar para el tratamiento sintomático, para episodios/brotes agudos o para el uso de fármacos modificadores de la enfermedad. La variedad existente de fármacos modificadores de la enfermedad permite flexibilidad en la elección de la mejor opción según el perfil de cada paciente. Además de los tratamientos farmacológicos, son importantes las terapias complementarias para la neurorrehabilitación y el control de los síntomas, como la psicología, la logopedia, la neuropsicología, la fisioterapia y la terapia ocupacional. Otros puntos discutidos recientemente en el tratamiento de la EM son el uso complementario de vitamina D, el uso de compuestos cannabinoides y una perspectiva futura del trasplante autólogo de células madre. Considerando la prevalencia y el impacto de la EM en la calidad de vida a largo plazo de los pacientes, la importancia del diagnóstico temprano y el inicio del tratamiento, así como la búsqueda de nueva evidencia para el mejor manejo terapéutico posible de la EM son fundamentales para la calidad de vida del paciente.A Esclerose Múltipla (EM) é uma doença crônica degenerativa que atinge o sistema nervoso central. O tratamento visa a diminuição do processo inflamatório e retardar o avanço da doença. Este trabalho analisa as opções terapêuticas existentes e atualmente disponíveis para o tratamento de pacientes com esclerose múltipla. Foi realizado um estudo epidemiológico, a partir de uma revisão integrativa dos dados disponíveis no PubMed, SciELO e Google Acadêmico, utilizando os descritores “esclerose múltipla” e “tratamento”. A terapia farmacológica para EM pode ser empregada para tratamento sintomático, de episódios agudos/surtos, ou pela utilização de medicamentos modificadores da doença. A variedade existente de medicamentos modificadores da doença permite flexibilidade na escolha da melhor opção de acordo com o perfil de cada paciente. Aliando-se aos tratamentos medicamentosos, terapias complementares são importantes para a neuroreabilitação e controle de sintomas, como a psicologia, fonoaudiologia, neuropsicologia, fisioterapia e terapia ocupacional. Outros pontos recentemente discutidos no tratamento da EM são a utilização complementar de vitamina D, o uso de compostos canabinoides, e uma perspectiva futura do transplante autólogo de células tronco. Considerando a prevalência e impacto da EM sobre a qualidade de vida dos pacientes a longo prazo, a importância do diagnóstico e início do tratamento precoce, bem como a busca por novas evidências para o melhor manejo terapêutico possível da EM são fundamentais para a qualidade de vida do paciente.Research, Society and Development2022-03-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2633110.33448/rsd-v11i4.26331Research, Society and Development; Vol. 11 No. 4; e7811426331Research, Society and Development; Vol. 11 Núm. 4; e7811426331Research, Society and Development; v. 11 n. 4; e78114263312525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/26331/23683Copyright (c) 2022 Lara Gomes Nery; Ana Cláudia Maia Mendonça da Costa; Gabriela Ramos Ribeiro; Gustavo Silva Oliveira; Rodolfo Lopes Vaz; Jalsi Tacon Arrudahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessNery, Lara Gomes Costa, Ana Cláudia Maia Mendonça daRibeiro, Gabriela Ramos Oliveira, Gustavo Silva Vaz, Rodolfo Lopes Arruda, Jalsi Tacon2022-03-27T17:17:09Zoai:ojs.pkp.sfu.ca:article/26331Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:23.958231Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Therapeutic options for the treatment of multiple sclerosis Opciones terapéuticas para el tratamiento de la esclerosis múltiple Opções terapêuticas para o tratamento da esclerose múltipla |
title |
Therapeutic options for the treatment of multiple sclerosis |
spellingShingle |
Therapeutic options for the treatment of multiple sclerosis Nery, Lara Gomes Esclerose Disseminada Terapêutica Terapias complementares. Esclerosis diseminada Terapia Terapias complementarias. Disseminated sclerosis Therapy Complementary therapies. |
title_short |
Therapeutic options for the treatment of multiple sclerosis |
title_full |
Therapeutic options for the treatment of multiple sclerosis |
title_fullStr |
Therapeutic options for the treatment of multiple sclerosis |
title_full_unstemmed |
Therapeutic options for the treatment of multiple sclerosis |
title_sort |
Therapeutic options for the treatment of multiple sclerosis |
author |
Nery, Lara Gomes |
author_facet |
Nery, Lara Gomes Costa, Ana Cláudia Maia Mendonça da Ribeiro, Gabriela Ramos Oliveira, Gustavo Silva Vaz, Rodolfo Lopes Arruda, Jalsi Tacon |
author_role |
author |
author2 |
Costa, Ana Cláudia Maia Mendonça da Ribeiro, Gabriela Ramos Oliveira, Gustavo Silva Vaz, Rodolfo Lopes Arruda, Jalsi Tacon |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Nery, Lara Gomes Costa, Ana Cláudia Maia Mendonça da Ribeiro, Gabriela Ramos Oliveira, Gustavo Silva Vaz, Rodolfo Lopes Arruda, Jalsi Tacon |
dc.subject.por.fl_str_mv |
Esclerose Disseminada Terapêutica Terapias complementares. Esclerosis diseminada Terapia Terapias complementarias. Disseminated sclerosis Therapy Complementary therapies. |
topic |
Esclerose Disseminada Terapêutica Terapias complementares. Esclerosis diseminada Terapia Terapias complementarias. Disseminated sclerosis Therapy Complementary therapies. |
description |
Multiple Sclerosis (MS) is a chronic degenerative disease that affects the central nervous system. Treatment is aimed at reducing the inflammatory process and delaying the progression of the disease. This work analyzes the existing and currently available therapeutic options for the treatment of patients with multiple sclerosis. An epidemiological study was carried out, based on an integrative review of data available in PubMed, SciELO and Google Scholar, using the descriptors “multiple sclerosis” and “treatment”. Pharmacological therapy for MS can be used for symptomatic treatment, for acute episodes/outbreaks, or for the use of disease-modifying drugs. The existing variety of disease-modifying drugs allows flexibility in choosing the best option according to each patient's profile. In addition to drug treatments, complementary therapies are important for neurorehabilitation and symptom control, such as psychology, speech therapy, neuropsychology, physical therapy and occupational therapy. Other points recently discussed in the treatment of MS are the supplementary use of vitamin D, the use of cannabinoid compounds, and a future perspective of autologous stem cell transplantation. Considering the prevalence and impact of MS on the long-term quality of life of patients, the importance of early diagnosis and initiation of treatment, as well as the search for new evidence for the best possible therapeutic management of MS are fundamental for quality of life. of the patient. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-03-11 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26331 10.33448/rsd-v11i4.26331 |
url |
https://rsdjournal.org/index.php/rsd/article/view/26331 |
identifier_str_mv |
10.33448/rsd-v11i4.26331 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26331/23683 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 4; e7811426331 Research, Society and Development; Vol. 11 Núm. 4; e7811426331 Research, Society and Development; v. 11 n. 4; e7811426331 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052762782957568 |