Oral mucositis in children with cancer: difficulties of evaluation and effective therapy
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/20018 |
Resumo: | Cancer is a public health problem in the world and, in children, the incidence of increase is around 1% per year. Despite its effectiveness, antineoplastic therapy causes effects of significant toxicity, often causing the patient to be hospitalized, difficult to continue with oncotherapy or not readjusted to the treatment for the non-progression of the disease. Oral mucositis is one of the most common deleterious effects; it causes pain, affects speech and nutrition, and makes the patient susceptible to sepsis. In children, the frequency of oral mucositis is around 65%. Its manifestations are evaluated using different scales and treated with different protocols. The objective of this work is to verify, in a systematic literature review, the state of the art in the evaluation of oral mucositis in children undergoing cancer treatment. Studies have shown that assessment is essential to establish treatment strategies, that protocols and scales used are inconsistent, and that there is no viable and valid system to score childhood mucositis caused by cancer, preventing a more effective therapeutic intervention. It was concluded that the Children's International Mucositis Evaluation Scale has been the scale with the greatest acceptability and validity according to its criteria. |
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Oral mucositis in children with cancer: difficulties of evaluation and effective therapy Mucositis oral en niños con cáncer: dificultades en la evaluación y terapia eficazMucosite oral em crianças com câncer: dificuldades de avaliação e de terapia efetivaNeoplasianeoplasiaquimioterapiaQuimioterapiaMucositemucositeProtocolo. protocoloNeoplasmChemotherapyMucositisProtocol.protocolneoplasiaNeoplasiaQuimioterapiaquimioterapiamucositisMucositisprotocoloProtocolo.Cancer is a public health problem in the world and, in children, the incidence of increase is around 1% per year. Despite its effectiveness, antineoplastic therapy causes effects of significant toxicity, often causing the patient to be hospitalized, difficult to continue with oncotherapy or not readjusted to the treatment for the non-progression of the disease. Oral mucositis is one of the most common deleterious effects; it causes pain, affects speech and nutrition, and makes the patient susceptible to sepsis. In children, the frequency of oral mucositis is around 65%. Its manifestations are evaluated using different scales and treated with different protocols. The objective of this work is to verify, in a systematic literature review, the state of the art in the evaluation of oral mucositis in children undergoing cancer treatment. Studies have shown that assessment is essential to establish treatment strategies, that protocols and scales used are inconsistent, and that there is no viable and valid system to score childhood mucositis caused by cancer, preventing a more effective therapeutic intervention. It was concluded that the Children's International Mucositis Evaluation Scale has been the scale with the greatest acceptability and validity according to its criteria. El cáncer es un problema de salud pública en el mundo y, en los niños, la incidencia de aumento es de alrededor del 1% anual. A pesar de su eficacia, la terapia antineoplásica provoca efectos de importante toxicidad, provocando a menudo la hospitalización del paciente, dificultad para continuar con la oncoterapia o no readaptación al tratamiento por la no progresión de la enfermedad. La mucositis oral es uno de los efectos deletéreos más comunes; causa dolor, afecta el habla y la nutrición y hace que el paciente sea susceptible a la sepsis. En los niños, la frecuencia de la mucositis oral es de alrededor del 65%. Sus manifestaciones se evalúan utilizando diferentes escalas y se tratan con diferentes protocolos. El objetivo de este trabajo es verificar, en una revisión sistemática de la literatura, el estado del arte en la evaluación de la mucositis oral en niños sometidos a tratamiento oncológico. Los estudios han demostrado que la evaluación es fundamental para establecer estrategias de tratamiento, que los protocolos y escalas utilizados son inconsistentes y que no existe un sistema viable y válido para puntuar la mucositis infantil por cáncer, evitando una intervención terapéutica más eficaz. Se concluyó que la Children's International Mucositis Evaluation Scale ha sido la escala con mayor aceptabilidad y validez según sus criterios.O câncer é um problema de saúde pública no mundo e, em crianças, a incidência de aumento é de cerca de 1% ao ano. Apesar da eficácia, a terapia antineoplásica provoca efeitos de significativa toxicidade, muitas vezes causando a hospitalização do paciente, dificuldades de continuação da oncoterapia ou não readequação do tratamento para a não progressão da doença. A mucosite oral é um dos efeitos deletérios mais comuns; causa dor, afeta a fala e a nutrição e torna o paciente suscetível à septicemia. Em crianças, a frequência da mucosite oral situa-se em torno de 65%. Suas manifestações são avaliadas por meio de escalas diferentes e tratadas com protocolos distintos. O objetivo deste trabalho é verificar, em uma revisão sistemática da literatura, o estado da arte da avaliação da mucosite oral em crianças sob tratamento oncológico. Estudos mostraram que a avaliação é fundamental para estabelecer as estratégias de tratamento, que protocolos e escalas utilizadas são inconsistentes e que inexiste um sistema viável e válido para pontuar a mucosite infantil causada por câncer, impedindo uma intervenção terapêutica mais efetiva. Concluiu-se que a Children’s International Mucositis Evaluation Scale vem sendo a escala de maior aceitabilidade e validade por seu critérios.Research, Society and Development2021-09-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2001810.33448/rsd-v10i11.20018Research, Society and Development; Vol. 10 No. 11; e435101120018Research, Society and Development; Vol. 10 Núm. 11; e435101120018Research, Society and Development; v. 10 n. 11; e4351011200182525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/20018/17690Copyright (c) 2021 Ana Bessa Muniz; Maria Aparecida Rodrigues de Holanda ; Kleyton Nolasco de Abreu; Samuel Barbosa Macedo; Ellen Roberta Lima Bessa; Lady Daiane Pereira Leite; Mariana Raquel da Cruz Vegian; Rivaldave Rodrigues de Holanda Cavalcante; Rodrigo Asfury Rodrigueshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMuniz, Ana BessaHolanda , Maria Aparecida Rodrigues de Abreu, Kleyton Nolasco de Macedo, Samuel Barbosa Bessa, Ellen Roberta Lima Leite, Lady Daiane Pereira Vegian, Mariana Raquel da Cruz Cavalcante, Rivaldave Rodrigues de Holanda Rodrigues, Rodrigo Asfury 2021-10-23T19:01:11Zoai:ojs.pkp.sfu.ca:article/20018Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:39:46.821965Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Oral mucositis in children with cancer: difficulties of evaluation and effective therapy Mucositis oral en niños con cáncer: dificultades en la evaluación y terapia eficaz Mucosite oral em crianças com câncer: dificuldades de avaliação e de terapia efetiva |
| title |
Oral mucositis in children with cancer: difficulties of evaluation and effective therapy |
| spellingShingle |
Oral mucositis in children with cancer: difficulties of evaluation and effective therapy Muniz, Ana Bessa Neoplasia neoplasia quimioterapia Quimioterapia Mucosite mucosite Protocolo. protocolo Neoplasm Chemotherapy Mucositis Protocol. protocol neoplasia Neoplasia Quimioterapia quimioterapia mucositis Mucositis protocolo Protocolo. |
| title_short |
Oral mucositis in children with cancer: difficulties of evaluation and effective therapy |
| title_full |
Oral mucositis in children with cancer: difficulties of evaluation and effective therapy |
| title_fullStr |
Oral mucositis in children with cancer: difficulties of evaluation and effective therapy |
| title_full_unstemmed |
Oral mucositis in children with cancer: difficulties of evaluation and effective therapy |
| title_sort |
Oral mucositis in children with cancer: difficulties of evaluation and effective therapy |
| author |
Muniz, Ana Bessa |
| author_facet |
Muniz, Ana Bessa Holanda , Maria Aparecida Rodrigues de Abreu, Kleyton Nolasco de Macedo, Samuel Barbosa Bessa, Ellen Roberta Lima Leite, Lady Daiane Pereira Vegian, Mariana Raquel da Cruz Cavalcante, Rivaldave Rodrigues de Holanda Rodrigues, Rodrigo Asfury |
| author_role |
author |
| author2 |
Holanda , Maria Aparecida Rodrigues de Abreu, Kleyton Nolasco de Macedo, Samuel Barbosa Bessa, Ellen Roberta Lima Leite, Lady Daiane Pereira Vegian, Mariana Raquel da Cruz Cavalcante, Rivaldave Rodrigues de Holanda Rodrigues, Rodrigo Asfury |
| author2_role |
author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Muniz, Ana Bessa Holanda , Maria Aparecida Rodrigues de Abreu, Kleyton Nolasco de Macedo, Samuel Barbosa Bessa, Ellen Roberta Lima Leite, Lady Daiane Pereira Vegian, Mariana Raquel da Cruz Cavalcante, Rivaldave Rodrigues de Holanda Rodrigues, Rodrigo Asfury |
| dc.subject.por.fl_str_mv |
Neoplasia neoplasia quimioterapia Quimioterapia Mucosite mucosite Protocolo. protocolo Neoplasm Chemotherapy Mucositis Protocol. protocol neoplasia Neoplasia Quimioterapia quimioterapia mucositis Mucositis protocolo Protocolo. |
| topic |
Neoplasia neoplasia quimioterapia Quimioterapia Mucosite mucosite Protocolo. protocolo Neoplasm Chemotherapy Mucositis Protocol. protocol neoplasia Neoplasia Quimioterapia quimioterapia mucositis Mucositis protocolo Protocolo. |
| description |
Cancer is a public health problem in the world and, in children, the incidence of increase is around 1% per year. Despite its effectiveness, antineoplastic therapy causes effects of significant toxicity, often causing the patient to be hospitalized, difficult to continue with oncotherapy or not readjusted to the treatment for the non-progression of the disease. Oral mucositis is one of the most common deleterious effects; it causes pain, affects speech and nutrition, and makes the patient susceptible to sepsis. In children, the frequency of oral mucositis is around 65%. Its manifestations are evaluated using different scales and treated with different protocols. The objective of this work is to verify, in a systematic literature review, the state of the art in the evaluation of oral mucositis in children undergoing cancer treatment. Studies have shown that assessment is essential to establish treatment strategies, that protocols and scales used are inconsistent, and that there is no viable and valid system to score childhood mucositis caused by cancer, preventing a more effective therapeutic intervention. It was concluded that the Children's International Mucositis Evaluation Scale has been the scale with the greatest acceptability and validity according to its criteria. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-09-05 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://rsdjournal.org/index.php/rsd/article/view/20018 10.33448/rsd-v10i11.20018 |
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https://rsdjournal.org/index.php/rsd/article/view/20018 |
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10.33448/rsd-v10i11.20018 |
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por |
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por |
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https://rsdjournal.org/index.php/rsd/article/view/20018/17690 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development; Vol. 10 No. 11; e435101120018 Research, Society and Development; Vol. 10 Núm. 11; e435101120018 Research, Society and Development; v. 10 n. 11; e435101120018 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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UNIFEI |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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1797052689015635968 |