Prevalence of microorganisms resistant to ciprofloxacin isolated in urinary tract infections at University Hospital of Recife/PE
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/30588 |
Resumo: | Urinary tract infection (UTI) is one of the main causes of medical consultation, second only to respiratory infections. The main etiologic agent is the bacterium Escherichia coli, but other bacteria, such as Klebsiella pneumoniae, Proteus spp., Enterobacter spp., may also be involved. Ciprofloxacin, from the quinolone class, is the drug of choice to treat UTI. It has high absorption capacity, good coverage by gram-negative bacteria and is available both orally and intravenously. However, microbial resistance to this class of drugs has been increasing. The present study aimed to identify, through the CCIH database of the HC-UFPE, the prevalence of ciprofloxacin-resistant microorganisms in patients with UTI. The research was a cross-sectional study on data from patients with UTI from January to December 2019, with CEP approval under CAAE number 20644719.3.3001.8807. The results showed that, of the 301 positive urine cultures, 82 showed resistance to ciprofloxacin. The most prevalent bacterium was E. coli. Most cases of infection affected women, with 193 female patients, 104 men and 4 newborns. Regarding the clinic, nephrology patients were the ones with the most UTIs. Growing resistance to ciprofloxacin may limit effective therapeutic options for treating UTI, and one of the causes is the indiscriminate and abusive use of antimicrobials. To minimize this situation, it is necessary to alert and make the population aware of the dangers and risks of using antimicrobials without a medical prescription and in the wrong way. |
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Prevalence of microorganisms resistant to ciprofloxacin isolated in urinary tract infections at University Hospital of Recife/PE Prevalencia de microorganismos resistentes a la ciprofloxacina aislada en infecciones del tracto urinario en el Hospital Universitario de Recife/PE Prevalência de microrganismos resistentes a ciprofloxacino isolados em infecções do trato urinário em Hospital Universitário de Recife/PE ITUEscherichia coliQuinolonas. ITUEscherichia coliQuinolonas.UTIEscherichia coliQuinolones.Urinary tract infection (UTI) is one of the main causes of medical consultation, second only to respiratory infections. The main etiologic agent is the bacterium Escherichia coli, but other bacteria, such as Klebsiella pneumoniae, Proteus spp., Enterobacter spp., may also be involved. Ciprofloxacin, from the quinolone class, is the drug of choice to treat UTI. It has high absorption capacity, good coverage by gram-negative bacteria and is available both orally and intravenously. However, microbial resistance to this class of drugs has been increasing. The present study aimed to identify, through the CCIH database of the HC-UFPE, the prevalence of ciprofloxacin-resistant microorganisms in patients with UTI. The research was a cross-sectional study on data from patients with UTI from January to December 2019, with CEP approval under CAAE number 20644719.3.3001.8807. The results showed that, of the 301 positive urine cultures, 82 showed resistance to ciprofloxacin. The most prevalent bacterium was E. coli. Most cases of infection affected women, with 193 female patients, 104 men and 4 newborns. Regarding the clinic, nephrology patients were the ones with the most UTIs. Growing resistance to ciprofloxacin may limit effective therapeutic options for treating UTI, and one of the causes is the indiscriminate and abusive use of antimicrobials. To minimize this situation, it is necessary to alert and make the population aware of the dangers and risks of using antimicrobials without a medical prescription and in the wrong way.La infección del tracto urinario (ITU) es una de las principales causas de consulta médica, sólo superada por las infecciones respiratorias. El principal agente etiológico es la bacteria Escherichia coli, pero también pueden estar implicadas otras bacterias, como Klebsiella pneumoniae, Proteus spp., Enterobacter spp. La ciprofloxacina, de la clase de las quinolonas, es el fármaco de elección para tratar la ITU. Tiene alta capacidad de absorción, buena cobertura por bacterias gramnegativas y está disponible tanto por vía oral como intravenosa. Sin embargo, la resistencia microbiana a esta clase de fármacos ha ido en aumento. El presente estudio tuvo como objetivo identificar, a través de la base de datos CCIH del HC-UFPE, la prevalencia de microorganismos resistentes a la ciprofloxacina en pacientes con ITU. La investigación fue un estudio transversal sobre datos de pacientes con ITU de enero a diciembre de 2019, con aprobación del CEP bajo el número CAAE 20644719.3.3001.8807. Los resultados mostraron que, de los 301 urocultivos positivos, 82 mostraron resistencia a la ciprofloxacina. La bacteria más prevalente fue E. coli. La mayoría de los casos de infección afectaron a mujeres, con 193 pacientes mujeres, 104 hombres y 4 recién nacidos. En cuanto a la consulta, los pacientes de nefrología fueron los que más ITU presentaron. La creciente resistencia a la ciprofloxacina puede limitar las opciones terapéuticas efectivas para el tratamiento de la ITU, y una de las causas es el uso indiscriminado y abusivo de antimicrobianos. Para minimizar esta situación, es necesario alertar y concientizar a la población sobre los peligros y riesgos del uso de antimicrobianos sin prescripción médica y de manera incorrecta.A infecção do trato urinário (ITU) é uma das principais causas de consulta médica, ficando atrás apenas das infecções respiratórias. O principal agente etiológico é a bactéria Escherichia coli, mas outras bactérias, como Klebsiella pneumoniae, Proteus spp., Enterobacter spp., também podem estar envolvidas. O ciprofloxacino, da classe das quinolonas, é a droga de escolha para tratar ITU. Possui alta capacidade de absorção, boa cobertura pelas bactérias gram-negativas e tem sua disponibilidade tanto oral quanto intravenosa. Entretanto, a resistência microbiana a essa classe de medicamentos tem sido crescente. O presente estudo objetivou identificar, através do banco de dados da CCIH do HC-UFPE, a prevalência de microrganismos resistentes a ciprofloxacino em pacientes com ITU. A pesquisa foi um estudo de corte transversal sobre dados de pacientes com ITU no período de janeiro a dezembro de 2019, com aprovação do CEP sob Número do CAAE 20644719.3.3001.8807. Os resultados demonstraram que, das 301 uroculturas positivas, 82 apresentaram resistência a ciprofloxacino. A bactéria mais prevalente foi E. coli. A maioria dos casos de infecção acometeu as mulheres, sendo encontradas 193 pacientes do sexo feminino, 104 homens e 4 recém-nascidos. Com relação à clínica, pacientes da nefrologia foram os que mais apresentaram ITU. A crescente resistência a ciprofloxacino pode limitar as opções terapêuticas eficazes para tratamento da ITU, e uma das causas é uso indiscriminado e abusivo dos antimicrobianos. Para minimizar esta situação, é necessário alertar e conscientizar a população para os perigos e riscos de utilizar antimicrobianos sem prescrição médica e de maneira equivocada.Research, Society and Development2022-06-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3058810.33448/rsd-v11i8.30588Research, Society and Development; Vol. 11 No. 8; e10411830588Research, Society and Development; Vol. 11 Núm. 8; e10411830588Research, Society and Development; v. 11 n. 8; e104118305882525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/30588/26312Copyright (c) 2022 Dayana Cecília da Silva Lima; Airton Vieira Leite Segundo; Ana Beatriz Paes de Lira Branco; Rafaella Henrique Sousa de Araújo Britto; Renata Prohaska Batista; Rodrigo Siqueira de Arruda Camara; José Manoel Wanderley Duarte Neto; Maria Carolina de Albuquerque Wanderleyhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessLima, Dayana Cecília da Silva Leite Segundo, Airton VieiraBranco, Ana Beatriz Paes de Lira Britto, Rafaella Henrique Sousa de Araújo Batista, Renata ProhaskaCamara, Rodrigo Siqueira de Arruda Duarte Neto, José Manoel Wanderley Wanderley, Maria Carolina de Albuquerque 2022-07-01T13:34:06Zoai:ojs.pkp.sfu.ca:article/30588Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:47:17.452078Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Prevalence of microorganisms resistant to ciprofloxacin isolated in urinary tract infections at University Hospital of Recife/PE Prevalencia de microorganismos resistentes a la ciprofloxacina aislada en infecciones del tracto urinario en el Hospital Universitario de Recife/PE Prevalência de microrganismos resistentes a ciprofloxacino isolados em infecções do trato urinário em Hospital Universitário de Recife/PE |
title |
Prevalence of microorganisms resistant to ciprofloxacin isolated in urinary tract infections at University Hospital of Recife/PE |
spellingShingle |
Prevalence of microorganisms resistant to ciprofloxacin isolated in urinary tract infections at University Hospital of Recife/PE Lima, Dayana Cecília da Silva ITU Escherichia coli Quinolonas. ITU Escherichia coli Quinolonas. UTI Escherichia coli Quinolones. |
title_short |
Prevalence of microorganisms resistant to ciprofloxacin isolated in urinary tract infections at University Hospital of Recife/PE |
title_full |
Prevalence of microorganisms resistant to ciprofloxacin isolated in urinary tract infections at University Hospital of Recife/PE |
title_fullStr |
Prevalence of microorganisms resistant to ciprofloxacin isolated in urinary tract infections at University Hospital of Recife/PE |
title_full_unstemmed |
Prevalence of microorganisms resistant to ciprofloxacin isolated in urinary tract infections at University Hospital of Recife/PE |
title_sort |
Prevalence of microorganisms resistant to ciprofloxacin isolated in urinary tract infections at University Hospital of Recife/PE |
author |
Lima, Dayana Cecília da Silva |
author_facet |
Lima, Dayana Cecília da Silva Leite Segundo, Airton Vieira Branco, Ana Beatriz Paes de Lira Britto, Rafaella Henrique Sousa de Araújo Batista, Renata Prohaska Camara, Rodrigo Siqueira de Arruda Duarte Neto, José Manoel Wanderley Wanderley, Maria Carolina de Albuquerque |
author_role |
author |
author2 |
Leite Segundo, Airton Vieira Branco, Ana Beatriz Paes de Lira Britto, Rafaella Henrique Sousa de Araújo Batista, Renata Prohaska Camara, Rodrigo Siqueira de Arruda Duarte Neto, José Manoel Wanderley Wanderley, Maria Carolina de Albuquerque |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Lima, Dayana Cecília da Silva Leite Segundo, Airton Vieira Branco, Ana Beatriz Paes de Lira Britto, Rafaella Henrique Sousa de Araújo Batista, Renata Prohaska Camara, Rodrigo Siqueira de Arruda Duarte Neto, José Manoel Wanderley Wanderley, Maria Carolina de Albuquerque |
dc.subject.por.fl_str_mv |
ITU Escherichia coli Quinolonas. ITU Escherichia coli Quinolonas. UTI Escherichia coli Quinolones. |
topic |
ITU Escherichia coli Quinolonas. ITU Escherichia coli Quinolonas. UTI Escherichia coli Quinolones. |
description |
Urinary tract infection (UTI) is one of the main causes of medical consultation, second only to respiratory infections. The main etiologic agent is the bacterium Escherichia coli, but other bacteria, such as Klebsiella pneumoniae, Proteus spp., Enterobacter spp., may also be involved. Ciprofloxacin, from the quinolone class, is the drug of choice to treat UTI. It has high absorption capacity, good coverage by gram-negative bacteria and is available both orally and intravenously. However, microbial resistance to this class of drugs has been increasing. The present study aimed to identify, through the CCIH database of the HC-UFPE, the prevalence of ciprofloxacin-resistant microorganisms in patients with UTI. The research was a cross-sectional study on data from patients with UTI from January to December 2019, with CEP approval under CAAE number 20644719.3.3001.8807. The results showed that, of the 301 positive urine cultures, 82 showed resistance to ciprofloxacin. The most prevalent bacterium was E. coli. Most cases of infection affected women, with 193 female patients, 104 men and 4 newborns. Regarding the clinic, nephrology patients were the ones with the most UTIs. Growing resistance to ciprofloxacin may limit effective therapeutic options for treating UTI, and one of the causes is the indiscriminate and abusive use of antimicrobials. To minimize this situation, it is necessary to alert and make the population aware of the dangers and risks of using antimicrobials without a medical prescription and in the wrong way. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-06-11 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/30588 10.33448/rsd-v11i8.30588 |
url |
https://rsdjournal.org/index.php/rsd/article/view/30588 |
identifier_str_mv |
10.33448/rsd-v11i8.30588 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/30588/26312 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 8; e10411830588 Research, Society and Development; Vol. 11 Núm. 8; e10411830588 Research, Society and Development; v. 11 n. 8; e10411830588 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052812441419776 |