Calcifying odontogenic cyst: A case report

Detalhes bibliográficos
Autor(a) principal: Godoi, Daniel Ferreira Candido
Data de Publicação: 2024
Outros Autores: Nazaré, Gabriel Henrique Vieira de, Nascimento, Augusto José Nogueira do, Frazão, Kamilly de Lourdes Ramalho, Godoi, Daniel Candido
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/44749
Resumo: The Calcifying Odontogenic Cyst (COC), also known as Gorlin's cyst, is a rare entity with histological variability, giving rise to terminological discussions. Despite attempts at standardization, discrepancies persist due to its biological complexity. Accounting for only 0.3% of oral biopsies, COC originates from remnants of the odontogenic epithelium, preferably in the maxilla. Its incidence shows no gender bias, occurring more frequently in the 20s and 30s, with a slow and asymptomatic evolution. The lesion can be associated with other odontogenic pathologies. Radiographically, it appears radiolucent, either unilocular or multilocular, with well-defined or poorly defined margins. Histological examination reveals a fibrous cystic wall with odontogenic epithelium, highlighting ghost cells. The recommended treatment is enucleation combined with curettage, with a low risk of recurrence, requiring evaluation in cases associated with other lesions. The restoration of compromised bone structures demands contemporary approaches to bone grafting and special periodontal interventions. The study presents a detailed case report of a COC in the anterior right maxilla, employing a descriptive and qualitative approach. The clinical case involves a 57-year-old patient with COC in the anterior right maxilla, treated with enucleation, curettage, and xenogeneic bone grafting. Histological analysis confirmed the diagnosis. A 1.5-year follow-up reveals favorable evolution, with bone neoformation and no signs of recurrence. This case report aims to add knowledge about this rare lesion and its clinical and radiographic aspects, as well as its diagnosis, possible prognosis and treatment.
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spelling Calcifying odontogenic cyst: A case reportQuístico odontogénico calcificante: Reporte de un casoCisto odontogênico calcificante: Um relato de casoGorlin's cystCalcifying odontogenic cystMaxillary grafting techniques.Quiste de GorlinQuiste odontogénico calcificanteTécnicas de injerto maxilar.Cisto de GorlinCisto odontogênico calcificanteTécnicas de enxerto maxilar.The Calcifying Odontogenic Cyst (COC), also known as Gorlin's cyst, is a rare entity with histological variability, giving rise to terminological discussions. Despite attempts at standardization, discrepancies persist due to its biological complexity. Accounting for only 0.3% of oral biopsies, COC originates from remnants of the odontogenic epithelium, preferably in the maxilla. Its incidence shows no gender bias, occurring more frequently in the 20s and 30s, with a slow and asymptomatic evolution. The lesion can be associated with other odontogenic pathologies. Radiographically, it appears radiolucent, either unilocular or multilocular, with well-defined or poorly defined margins. Histological examination reveals a fibrous cystic wall with odontogenic epithelium, highlighting ghost cells. The recommended treatment is enucleation combined with curettage, with a low risk of recurrence, requiring evaluation in cases associated with other lesions. The restoration of compromised bone structures demands contemporary approaches to bone grafting and special periodontal interventions. The study presents a detailed case report of a COC in the anterior right maxilla, employing a descriptive and qualitative approach. The clinical case involves a 57-year-old patient with COC in the anterior right maxilla, treated with enucleation, curettage, and xenogeneic bone grafting. Histological analysis confirmed the diagnosis. A 1.5-year follow-up reveals favorable evolution, with bone neoformation and no signs of recurrence. This case report aims to add knowledge about this rare lesion and its clinical and radiographic aspects, as well as its diagnosis, possible prognosis and treatment.El Cisto Odontogénico Calcificante (COC), también conocido como cisto de Gorlin, es una entidad rara con variabilidad histológica que ha generado debates terminológicos. A pesar de los intentos de estandarización, persisten discrepancias debido a su complejidad biológica. Representando solo el 0,3% de las biopsias orales, el COC se origina en restos del epitelio odontogénico, preferentemente en la maxila. Su incidencia no muestra sesgo de género, siendo más frecuente en las décadas de los 20 y 30, con una evolución lenta y asintomática. La lesión puede asociarse con otras patologías odontogénicas. Radiográficamente, se presenta radiolúcido, pudiendo ser unilocular o multilocular, con márgenes bien o mal definidos. La aproximación histológica revela una pared quística fibrosa con epitelio odontogénico, destacando células fantasmas. El tratamiento recomendado es la enucleación asociada a la curetaje, con bajo riesgo de recidiva, siendo necesario evaluar casos asociados con otras lesiones. La restauración de las estructuras óseas comprometidas requiere enfoques contemporáneos de injerto óseo e intervenciones periodontales especiales. El estudio presenta un detallado informe de caso de un COC en la maxila anterior derecha, utilizando un enfoque descriptivo y cualitativo. El caso clínico involucra a una paciente de 57 años con COC en la maxila anterior derecha, tratada con enucleación, curetaje e injerto óseo xenógeno. El análisis histológico confirmó el diagnóstico. El seguimiento de 1,5 años revela una evolución favorable, con neoformación ósea y ausencia de recidiva. Este informe de caso pretende aportar conocimientos sobre esta lesión poco frecuente y sus aspectos clínicos y radiográficos, así como sobre su diagnóstico, posible pronóstico y tratamiento.O Cisto Odontogênico Calcificante (COC), também conhecido como cisto de Gorlin, é uma entidade rara com variabilidade histológica, suscitando discussões terminológicas. Apesar de tentativas de padronização, persistem discrepâncias devido à sua complexidade biológica. Representando apenas 0,3% das biópsias orais, o COC origina-se de remanescentes do epitélio odontogênico, preferencialmente na maxila. Sua incidência não mostra viés de gênero, ocorrendo mais frequentemente nas décadas de 20 e 30, com evolução lenta e assintomática. A lesão pode associar-se a outras patologias odontogênicas. Radiograficamente, apresenta-se radiolúcida, podendo ser unilocular ou multilocular, com margens bem ou mal definidas. A abordagem histológica revela uma parede cística fibrosa com epitélio odontogênico, destacando células-fantasmas. O tratamento preconizado é a enucleação associada à curetagem, com baixo risco de recidiva, sendo necessário avaliar casos associados a outras lesões. A restauração das estruturas ósseas comprometidas exige abordagens contemporâneas de enxerto ósseo e intervenções periodontais especiais. O estudo apresenta um relato de caso detalhado de um COC na maxila anterior direita, adotando abordagem descritiva e qualitativa. O caso clínico envolve uma paciente de 57 anos com COC na maxila anterior direita, tratada com enucleação, curetagem e enxerto ósseo xenógeno. A análise histológica confirmou o diagnóstico. O acompanhamento de 1,5 anos revela evolução favorável, com neoformação óssea e ausência de recidiva. O presente relato de caso tem o objetivo de agregar conhecimento sobre esta lesão rara e seus aspectos clínicos e radiográficos, assim como seu diagnóstico, possível prognóstico e tratamento.Research, Society and Development2024-01-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4474910.33448/rsd-v13i1.44749Research, Society and Development; Vol. 13 No. 1; e4913144749Research, Society and Development; Vol. 13 Núm. 1; e4913144749Research, Society and Development; v. 13 n. 1; e49131447492525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/44749/35757Copyright (c) 2024 Daniel Ferreira Candido Godoi; Gabriel Henrique Vieira de Nazaré; Augusto José Nogueira do Nascimento; Kamilly de Lourdes Ramalho Frazão; Daniel Candido Godoihttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGodoi, Daniel Ferreira CandidoNazaré, Gabriel Henrique Vieira de Nascimento, Augusto José Nogueira do Frazão, Kamilly de Lourdes Ramalho Godoi, Daniel Candido 2024-02-01T09:48:39Zoai:ojs.pkp.sfu.ca:article/44749Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-02-01T09:48:39Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Calcifying odontogenic cyst: A case report
Quístico odontogénico calcificante: Reporte de un caso
Cisto odontogênico calcificante: Um relato de caso
title Calcifying odontogenic cyst: A case report
spellingShingle Calcifying odontogenic cyst: A case report
Godoi, Daniel Ferreira Candido
Gorlin's cyst
Calcifying odontogenic cyst
Maxillary grafting techniques.
Quiste de Gorlin
Quiste odontogénico calcificante
Técnicas de injerto maxilar.
Cisto de Gorlin
Cisto odontogênico calcificante
Técnicas de enxerto maxilar.
title_short Calcifying odontogenic cyst: A case report
title_full Calcifying odontogenic cyst: A case report
title_fullStr Calcifying odontogenic cyst: A case report
title_full_unstemmed Calcifying odontogenic cyst: A case report
title_sort Calcifying odontogenic cyst: A case report
author Godoi, Daniel Ferreira Candido
author_facet Godoi, Daniel Ferreira Candido
Nazaré, Gabriel Henrique Vieira de
Nascimento, Augusto José Nogueira do
Frazão, Kamilly de Lourdes Ramalho
Godoi, Daniel Candido
author_role author
author2 Nazaré, Gabriel Henrique Vieira de
Nascimento, Augusto José Nogueira do
Frazão, Kamilly de Lourdes Ramalho
Godoi, Daniel Candido
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Godoi, Daniel Ferreira Candido
Nazaré, Gabriel Henrique Vieira de
Nascimento, Augusto José Nogueira do
Frazão, Kamilly de Lourdes Ramalho
Godoi, Daniel Candido
dc.subject.por.fl_str_mv Gorlin's cyst
Calcifying odontogenic cyst
Maxillary grafting techniques.
Quiste de Gorlin
Quiste odontogénico calcificante
Técnicas de injerto maxilar.
Cisto de Gorlin
Cisto odontogênico calcificante
Técnicas de enxerto maxilar.
topic Gorlin's cyst
Calcifying odontogenic cyst
Maxillary grafting techniques.
Quiste de Gorlin
Quiste odontogénico calcificante
Técnicas de injerto maxilar.
Cisto de Gorlin
Cisto odontogênico calcificante
Técnicas de enxerto maxilar.
description The Calcifying Odontogenic Cyst (COC), also known as Gorlin's cyst, is a rare entity with histological variability, giving rise to terminological discussions. Despite attempts at standardization, discrepancies persist due to its biological complexity. Accounting for only 0.3% of oral biopsies, COC originates from remnants of the odontogenic epithelium, preferably in the maxilla. Its incidence shows no gender bias, occurring more frequently in the 20s and 30s, with a slow and asymptomatic evolution. The lesion can be associated with other odontogenic pathologies. Radiographically, it appears radiolucent, either unilocular or multilocular, with well-defined or poorly defined margins. Histological examination reveals a fibrous cystic wall with odontogenic epithelium, highlighting ghost cells. The recommended treatment is enucleation combined with curettage, with a low risk of recurrence, requiring evaluation in cases associated with other lesions. The restoration of compromised bone structures demands contemporary approaches to bone grafting and special periodontal interventions. The study presents a detailed case report of a COC in the anterior right maxilla, employing a descriptive and qualitative approach. The clinical case involves a 57-year-old patient with COC in the anterior right maxilla, treated with enucleation, curettage, and xenogeneic bone grafting. Histological analysis confirmed the diagnosis. A 1.5-year follow-up reveals favorable evolution, with bone neoformation and no signs of recurrence. This case report aims to add knowledge about this rare lesion and its clinical and radiographic aspects, as well as its diagnosis, possible prognosis and treatment.
publishDate 2024
dc.date.none.fl_str_mv 2024-01-11
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status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/44749
10.33448/rsd-v13i1.44749
url https://rsdjournal.org/index.php/rsd/article/view/44749
identifier_str_mv 10.33448/rsd-v13i1.44749
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/44749/35757
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 13 No. 1; e4913144749
Research, Society and Development; Vol. 13 Núm. 1; e4913144749
Research, Society and Development; v. 13 n. 1; e4913144749
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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