Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery

Detalhes bibliográficos
Autor(a) principal: Galli, Stéfani
Data de Publicação: 2021
Outros Autores: Costa, Mário Augusto Cray da, Souza, Ana Carolina Mello Fontoura de, Scomparin, Dionizia Xavier
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/13982
Resumo: Objective: To analyze whether the incidence of respiratory infections in the postoperative period of cardiac surgery is lower in patients immunized with the 13-valent pneumococcal conjugate vaccine. To study the main risk factors related to the development of infections in patients undergoing cardiac surgery. Methodology: 40 patients were included in the study, randomized 1: 1 to receive pneumococcal vaccine or placebo, 14 days before undergoing elective cardiac surgery. The incidence of infections in the 30 postoperative days was compared between groups. Results: There were 6 respiratory infections in the vaccine group and 2 in the placebo group (p=0.2024) and one death in the placebo group and none in the vaccine group (p=0.3173). Chronic obstructive pulmonary disease (p=0.003), diabetes mellitus (p=0.047) and peripheral arterial disease (p=0.0001) were listed as risk factors for the development of infections, which generated an increase in hospital stay (95% CI : 1.33- 7.13; p =0.0147) and ICU stay in the postoperative period (95% CI: 1.87- 33.45; p=0.0025). Conclusion: The application of pneumococcal vaccine 13v did not influence the development of postoperative pulmonary infections. Chronic obstructive pulmonary disease, diabetes mellitus and peripheral arterial disease were identified as risk factors for the development of infections, increasing the length of total hospital stay and time in the ICU.
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spelling Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgeryEfecto de la inmunización neumocócica preoperatoria sobre la incidencia de la infección respiratoria en el postoperatorio de la cirugía cardíacaEfeito da imunização pneumocócica pré-operatória na incidência de infecção respiratória no pós-operatório de cirurgia cardíacaPneumoniaCirurgia TorácicaPneumonia pneumocócicaImunizaçãoVacinas pneumocócicas.PneumoniaThoracic SurgeryPneumococcal PneumoniaImmunizationPneumococcal vaccines.NeumoníaCirugía TorácicaNeumonía NeumocócicaInmunizaciónVacunas neumocócicas.Objective: To analyze whether the incidence of respiratory infections in the postoperative period of cardiac surgery is lower in patients immunized with the 13-valent pneumococcal conjugate vaccine. To study the main risk factors related to the development of infections in patients undergoing cardiac surgery. Methodology: 40 patients were included in the study, randomized 1: 1 to receive pneumococcal vaccine or placebo, 14 days before undergoing elective cardiac surgery. The incidence of infections in the 30 postoperative days was compared between groups. Results: There were 6 respiratory infections in the vaccine group and 2 in the placebo group (p=0.2024) and one death in the placebo group and none in the vaccine group (p=0.3173). Chronic obstructive pulmonary disease (p=0.003), diabetes mellitus (p=0.047) and peripheral arterial disease (p=0.0001) were listed as risk factors for the development of infections, which generated an increase in hospital stay (95% CI : 1.33- 7.13; p =0.0147) and ICU stay in the postoperative period (95% CI: 1.87- 33.45; p=0.0025). Conclusion: The application of pneumococcal vaccine 13v did not influence the development of postoperative pulmonary infections. Chronic obstructive pulmonary disease, diabetes mellitus and peripheral arterial disease were identified as risk factors for the development of infections, increasing the length of total hospital stay and time in the ICU.Objetivo: Analizar si la incidencia de infecciones respiratorias tras la cirugía cardíaca es menor en los pacientes inmunizados con la vacuna neumocócica conjugada 13-valente. Estudiar los principales factores de riesgo relacionados con el desarrollo de infecciones en pacientes sometidos a cirugía cardíaca. Metodología: Se incluyeron en el estudio 40 pacientes, aleatorizados 1:1 para recibir la vacuna neumocócica o un placebo, 14 días antes de someterse a una cirugía cardíaca electiva. La incidencia de infecciones en los 30 días postoperatorios se comparó entre los grupos mediante el cálculo de la media, la mediana y el riesgo relativo, a través de las pruebas T de Student, Mann-Whitney, Fischer y Chi-cuadrado. Resultados: Se produjeron seis infecciones respiratorias en el grupo de la vacuna y dos en el grupo del placebo (p= 0,2024) y una muerte en el grupo del placebo y ninguna en el grupo de la vacuna (p= 0,3173).  La enfermedad pulmonar obstructiva crónica (p= 0,003), la diabetes mellitus (p=0,047) y la enfermedad arterial periférica (p=0,0001) se relacionaron como factores de riesgo para desarrollar infecciones, lo que generó un aumento de la duración de la estancia (IC 95%: 1,33- 7,13; p=0,0147) y de la estancia postoperatoria en la UCI (IC 95%: 1,87- 33,45; p= 0,0025). Conclusión: La aplicación de la vacuna neumocócica 13v no influyó en el desarrollo de infecciones pulmonares postoperatorias. La enfermedad pulmonar obstructiva crónica, la diabetes mellitus y la enfermedad arterial periférica fueron consideradas como factores de riesgo para el desarrollo de infecciones, aumentando el tiempo de internamiento total y el tiempo de IU.Objetivo: Analisar se a incidência de infecções respiratórias no pós-operatório de cirurgias cardíacas é menor em pacientes imunizados com a vacina pneumocócica conjugada 13- valente. Estudar quais os principais fatores de risco relacionados ao desenvolvimento de infecções nos pacientes submetidos a cirurgia cardíaca. Metodologia: Foram incluídos no estudo 40 pacientes, randomizados 1:1 para receber vacina pneumocócica ou placebo, 14 dias antes de serem submetidos a cirurgia cardíaca eletiva. A incidência de infecções nos 30 dias de pós-operatório foi comparada entre os grupos através de cálculos de média, mediana e risco relativo, pelos testes T de Student, Mann-Whitney, Fischer e Qui-quadrado. Resultados: Ocorreram 6 infecções respiratórias no grupo vacina e 2 no grupo placebo (p= 0,2024) e um óbito no grupo placebo e nenhum no grupo vacina (p= 0,3173).  Doença pulmonar obstrutiva crônica (p= 0,003), diabetes mellitus (p=0,047) e doença arterial periférica (p=0,0001) foram relacionados como fatores de risco para desenvolvimento de infecções, que geraram aumento do tempo de internação (95% IC: 1,33- 7,13; p=0,0147) e permanência em UTI no pós-operatório (95% IC: 1,87- 33,45; p= 0,0025). Conclusão: A aplicação da vacina pneumocócica 13v não influenciou no desenvolvimento de infecções pulmonares pós-operatórias. Doença pulmonar obstrutiva crônica, diabetes mellitus e doença arterial periférica foram apontadas como fator de risco para o desenvolvimento de infecções, aumentando o tempo de internamento total e tempo em UTI.Research, Society and Development2021-04-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1398210.33448/rsd-v10i4.13982Research, Society and Development; Vol. 10 No. 4; e11410413982Research, Society and Development; Vol. 10 Núm. 4; e11410413982Research, Society and Development; v. 10 n. 4; e114104139822525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/13982/12482Copyright (c) 2021 Stéfani Galli; Mário Augusto Cray da Costa; Ana Carolina Mello Fontoura de Souza; Dionizia Xavier Scomparinhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGalli, StéfaniCosta, Mário Augusto Cray daSouza, Ana Carolina Mello Fontoura de Scomparin, Dionizia Xavier2021-04-25T11:21:26Zoai:ojs.pkp.sfu.ca:article/13982Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:35:12.588515Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery
Efecto de la inmunización neumocócica preoperatoria sobre la incidencia de la infección respiratoria en el postoperatorio de la cirugía cardíaca
Efeito da imunização pneumocócica pré-operatória na incidência de infecção respiratória no pós-operatório de cirurgia cardíaca
title Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery
spellingShingle Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery
Galli, Stéfani
Pneumonia
Cirurgia Torácica
Pneumonia pneumocócica
Imunização
Vacinas pneumocócicas.
Pneumonia
Thoracic Surgery
Pneumococcal Pneumonia
Immunization
Pneumococcal vaccines.
Neumonía
Cirugía Torácica
Neumonía Neumocócica
Inmunización
Vacunas neumocócicas.
title_short Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery
title_full Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery
title_fullStr Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery
title_full_unstemmed Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery
title_sort Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery
author Galli, Stéfani
author_facet Galli, Stéfani
Costa, Mário Augusto Cray da
Souza, Ana Carolina Mello Fontoura de
Scomparin, Dionizia Xavier
author_role author
author2 Costa, Mário Augusto Cray da
Souza, Ana Carolina Mello Fontoura de
Scomparin, Dionizia Xavier
author2_role author
author
author
dc.contributor.author.fl_str_mv Galli, Stéfani
Costa, Mário Augusto Cray da
Souza, Ana Carolina Mello Fontoura de
Scomparin, Dionizia Xavier
dc.subject.por.fl_str_mv Pneumonia
Cirurgia Torácica
Pneumonia pneumocócica
Imunização
Vacinas pneumocócicas.
Pneumonia
Thoracic Surgery
Pneumococcal Pneumonia
Immunization
Pneumococcal vaccines.
Neumonía
Cirugía Torácica
Neumonía Neumocócica
Inmunización
Vacunas neumocócicas.
topic Pneumonia
Cirurgia Torácica
Pneumonia pneumocócica
Imunização
Vacinas pneumocócicas.
Pneumonia
Thoracic Surgery
Pneumococcal Pneumonia
Immunization
Pneumococcal vaccines.
Neumonía
Cirugía Torácica
Neumonía Neumocócica
Inmunización
Vacunas neumocócicas.
description Objective: To analyze whether the incidence of respiratory infections in the postoperative period of cardiac surgery is lower in patients immunized with the 13-valent pneumococcal conjugate vaccine. To study the main risk factors related to the development of infections in patients undergoing cardiac surgery. Methodology: 40 patients were included in the study, randomized 1: 1 to receive pneumococcal vaccine or placebo, 14 days before undergoing elective cardiac surgery. The incidence of infections in the 30 postoperative days was compared between groups. Results: There were 6 respiratory infections in the vaccine group and 2 in the placebo group (p=0.2024) and one death in the placebo group and none in the vaccine group (p=0.3173). Chronic obstructive pulmonary disease (p=0.003), diabetes mellitus (p=0.047) and peripheral arterial disease (p=0.0001) were listed as risk factors for the development of infections, which generated an increase in hospital stay (95% CI : 1.33- 7.13; p =0.0147) and ICU stay in the postoperative period (95% CI: 1.87- 33.45; p=0.0025). Conclusion: The application of pneumococcal vaccine 13v did not influence the development of postoperative pulmonary infections. Chronic obstructive pulmonary disease, diabetes mellitus and peripheral arterial disease were identified as risk factors for the development of infections, increasing the length of total hospital stay and time in the ICU.
publishDate 2021
dc.date.none.fl_str_mv 2021-04-02
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/13982
10.33448/rsd-v10i4.13982
url https://rsdjournal.org/index.php/rsd/article/view/13982
identifier_str_mv 10.33448/rsd-v10i4.13982
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/13982/12482
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 4; e11410413982
Research, Society and Development; Vol. 10 Núm. 4; e11410413982
Research, Society and Development; v. 10 n. 4; e11410413982
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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