Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/13982 |
Resumo: | Objective: To analyze whether the incidence of respiratory infections in the postoperative period of cardiac surgery is lower in patients immunized with the 13-valent pneumococcal conjugate vaccine. To study the main risk factors related to the development of infections in patients undergoing cardiac surgery. Methodology: 40 patients were included in the study, randomized 1: 1 to receive pneumococcal vaccine or placebo, 14 days before undergoing elective cardiac surgery. The incidence of infections in the 30 postoperative days was compared between groups. Results: There were 6 respiratory infections in the vaccine group and 2 in the placebo group (p=0.2024) and one death in the placebo group and none in the vaccine group (p=0.3173). Chronic obstructive pulmonary disease (p=0.003), diabetes mellitus (p=0.047) and peripheral arterial disease (p=0.0001) were listed as risk factors for the development of infections, which generated an increase in hospital stay (95% CI : 1.33- 7.13; p =0.0147) and ICU stay in the postoperative period (95% CI: 1.87- 33.45; p=0.0025). Conclusion: The application of pneumococcal vaccine 13v did not influence the development of postoperative pulmonary infections. Chronic obstructive pulmonary disease, diabetes mellitus and peripheral arterial disease were identified as risk factors for the development of infections, increasing the length of total hospital stay and time in the ICU. |
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Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgeryEfecto de la inmunización neumocócica preoperatoria sobre la incidencia de la infección respiratoria en el postoperatorio de la cirugía cardíacaEfeito da imunização pneumocócica pré-operatória na incidência de infecção respiratória no pós-operatório de cirurgia cardíacaPneumoniaCirurgia TorácicaPneumonia pneumocócicaImunizaçãoVacinas pneumocócicas.PneumoniaThoracic SurgeryPneumococcal PneumoniaImmunizationPneumococcal vaccines.NeumoníaCirugía TorácicaNeumonía NeumocócicaInmunizaciónVacunas neumocócicas.Objective: To analyze whether the incidence of respiratory infections in the postoperative period of cardiac surgery is lower in patients immunized with the 13-valent pneumococcal conjugate vaccine. To study the main risk factors related to the development of infections in patients undergoing cardiac surgery. Methodology: 40 patients were included in the study, randomized 1: 1 to receive pneumococcal vaccine or placebo, 14 days before undergoing elective cardiac surgery. The incidence of infections in the 30 postoperative days was compared between groups. Results: There were 6 respiratory infections in the vaccine group and 2 in the placebo group (p=0.2024) and one death in the placebo group and none in the vaccine group (p=0.3173). Chronic obstructive pulmonary disease (p=0.003), diabetes mellitus (p=0.047) and peripheral arterial disease (p=0.0001) were listed as risk factors for the development of infections, which generated an increase in hospital stay (95% CI : 1.33- 7.13; p =0.0147) and ICU stay in the postoperative period (95% CI: 1.87- 33.45; p=0.0025). Conclusion: The application of pneumococcal vaccine 13v did not influence the development of postoperative pulmonary infections. Chronic obstructive pulmonary disease, diabetes mellitus and peripheral arterial disease were identified as risk factors for the development of infections, increasing the length of total hospital stay and time in the ICU.Objetivo: Analizar si la incidencia de infecciones respiratorias tras la cirugía cardíaca es menor en los pacientes inmunizados con la vacuna neumocócica conjugada 13-valente. Estudiar los principales factores de riesgo relacionados con el desarrollo de infecciones en pacientes sometidos a cirugía cardíaca. Metodología: Se incluyeron en el estudio 40 pacientes, aleatorizados 1:1 para recibir la vacuna neumocócica o un placebo, 14 días antes de someterse a una cirugía cardíaca electiva. La incidencia de infecciones en los 30 días postoperatorios se comparó entre los grupos mediante el cálculo de la media, la mediana y el riesgo relativo, a través de las pruebas T de Student, Mann-Whitney, Fischer y Chi-cuadrado. Resultados: Se produjeron seis infecciones respiratorias en el grupo de la vacuna y dos en el grupo del placebo (p= 0,2024) y una muerte en el grupo del placebo y ninguna en el grupo de la vacuna (p= 0,3173). La enfermedad pulmonar obstructiva crónica (p= 0,003), la diabetes mellitus (p=0,047) y la enfermedad arterial periférica (p=0,0001) se relacionaron como factores de riesgo para desarrollar infecciones, lo que generó un aumento de la duración de la estancia (IC 95%: 1,33- 7,13; p=0,0147) y de la estancia postoperatoria en la UCI (IC 95%: 1,87- 33,45; p= 0,0025). Conclusión: La aplicación de la vacuna neumocócica 13v no influyó en el desarrollo de infecciones pulmonares postoperatorias. La enfermedad pulmonar obstructiva crónica, la diabetes mellitus y la enfermedad arterial periférica fueron consideradas como factores de riesgo para el desarrollo de infecciones, aumentando el tiempo de internamiento total y el tiempo de IU.Objetivo: Analisar se a incidência de infecções respiratórias no pós-operatório de cirurgias cardíacas é menor em pacientes imunizados com a vacina pneumocócica conjugada 13- valente. Estudar quais os principais fatores de risco relacionados ao desenvolvimento de infecções nos pacientes submetidos a cirurgia cardíaca. Metodologia: Foram incluídos no estudo 40 pacientes, randomizados 1:1 para receber vacina pneumocócica ou placebo, 14 dias antes de serem submetidos a cirurgia cardíaca eletiva. A incidência de infecções nos 30 dias de pós-operatório foi comparada entre os grupos através de cálculos de média, mediana e risco relativo, pelos testes T de Student, Mann-Whitney, Fischer e Qui-quadrado. Resultados: Ocorreram 6 infecções respiratórias no grupo vacina e 2 no grupo placebo (p= 0,2024) e um óbito no grupo placebo e nenhum no grupo vacina (p= 0,3173). Doença pulmonar obstrutiva crônica (p= 0,003), diabetes mellitus (p=0,047) e doença arterial periférica (p=0,0001) foram relacionados como fatores de risco para desenvolvimento de infecções, que geraram aumento do tempo de internação (95% IC: 1,33- 7,13; p=0,0147) e permanência em UTI no pós-operatório (95% IC: 1,87- 33,45; p= 0,0025). Conclusão: A aplicação da vacina pneumocócica 13v não influenciou no desenvolvimento de infecções pulmonares pós-operatórias. Doença pulmonar obstrutiva crônica, diabetes mellitus e doença arterial periférica foram apontadas como fator de risco para o desenvolvimento de infecções, aumentando o tempo de internamento total e tempo em UTI.Research, Society and Development2021-04-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1398210.33448/rsd-v10i4.13982Research, Society and Development; Vol. 10 No. 4; e11410413982Research, Society and Development; Vol. 10 Núm. 4; e11410413982Research, Society and Development; v. 10 n. 4; e114104139822525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/13982/12482Copyright (c) 2021 Stéfani Galli; Mário Augusto Cray da Costa; Ana Carolina Mello Fontoura de Souza; Dionizia Xavier Scomparinhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGalli, StéfaniCosta, Mário Augusto Cray daSouza, Ana Carolina Mello Fontoura de Scomparin, Dionizia Xavier2021-04-25T11:21:26Zoai:ojs.pkp.sfu.ca:article/13982Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:35:12.588515Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery Efecto de la inmunización neumocócica preoperatoria sobre la incidencia de la infección respiratoria en el postoperatorio de la cirugía cardíaca Efeito da imunização pneumocócica pré-operatória na incidência de infecção respiratória no pós-operatório de cirurgia cardíaca |
title |
Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery |
spellingShingle |
Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery Galli, Stéfani Pneumonia Cirurgia Torácica Pneumonia pneumocócica Imunização Vacinas pneumocócicas. Pneumonia Thoracic Surgery Pneumococcal Pneumonia Immunization Pneumococcal vaccines. Neumonía Cirugía Torácica Neumonía Neumocócica Inmunización Vacunas neumocócicas. |
title_short |
Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery |
title_full |
Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery |
title_fullStr |
Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery |
title_full_unstemmed |
Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery |
title_sort |
Effect of preoperative pneumococcal immunization on the incidence of respiratory infection in the postoperative period of cardiac surgery |
author |
Galli, Stéfani |
author_facet |
Galli, Stéfani Costa, Mário Augusto Cray da Souza, Ana Carolina Mello Fontoura de Scomparin, Dionizia Xavier |
author_role |
author |
author2 |
Costa, Mário Augusto Cray da Souza, Ana Carolina Mello Fontoura de Scomparin, Dionizia Xavier |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Galli, Stéfani Costa, Mário Augusto Cray da Souza, Ana Carolina Mello Fontoura de Scomparin, Dionizia Xavier |
dc.subject.por.fl_str_mv |
Pneumonia Cirurgia Torácica Pneumonia pneumocócica Imunização Vacinas pneumocócicas. Pneumonia Thoracic Surgery Pneumococcal Pneumonia Immunization Pneumococcal vaccines. Neumonía Cirugía Torácica Neumonía Neumocócica Inmunización Vacunas neumocócicas. |
topic |
Pneumonia Cirurgia Torácica Pneumonia pneumocócica Imunização Vacinas pneumocócicas. Pneumonia Thoracic Surgery Pneumococcal Pneumonia Immunization Pneumococcal vaccines. Neumonía Cirugía Torácica Neumonía Neumocócica Inmunización Vacunas neumocócicas. |
description |
Objective: To analyze whether the incidence of respiratory infections in the postoperative period of cardiac surgery is lower in patients immunized with the 13-valent pneumococcal conjugate vaccine. To study the main risk factors related to the development of infections in patients undergoing cardiac surgery. Methodology: 40 patients were included in the study, randomized 1: 1 to receive pneumococcal vaccine or placebo, 14 days before undergoing elective cardiac surgery. The incidence of infections in the 30 postoperative days was compared between groups. Results: There were 6 respiratory infections in the vaccine group and 2 in the placebo group (p=0.2024) and one death in the placebo group and none in the vaccine group (p=0.3173). Chronic obstructive pulmonary disease (p=0.003), diabetes mellitus (p=0.047) and peripheral arterial disease (p=0.0001) were listed as risk factors for the development of infections, which generated an increase in hospital stay (95% CI : 1.33- 7.13; p =0.0147) and ICU stay in the postoperative period (95% CI: 1.87- 33.45; p=0.0025). Conclusion: The application of pneumococcal vaccine 13v did not influence the development of postoperative pulmonary infections. Chronic obstructive pulmonary disease, diabetes mellitus and peripheral arterial disease were identified as risk factors for the development of infections, increasing the length of total hospital stay and time in the ICU. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-04-02 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/13982 10.33448/rsd-v10i4.13982 |
url |
https://rsdjournal.org/index.php/rsd/article/view/13982 |
identifier_str_mv |
10.33448/rsd-v10i4.13982 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/13982/12482 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 4; e11410413982 Research, Society and Development; Vol. 10 Núm. 4; e11410413982 Research, Society and Development; v. 10 n. 4; e11410413982 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052784722313216 |