Efficacy of the non-instrumentation endodontic treatment with CTZ paste in primary molars: Protocol of a multicenter randomized clinical trial with two years of follow-up

• Autor(a) principal: Santos, Pablo Silveira
• Data de Publicação: 2022
• Outros Autores: Oliveira, Natália Matsuda de, Ramos, Tatiane, Dornellas, Ana Paula, Rocha, Aurélio de Oliveira, Vitali, Filipe Colombo, Moccelini, Bárbara Suelen, Rigo, Danielle Cristina Alves, Marques, Renata Pereira de Samuel, Pontes, Laura Regina Antunes, Matos, Juliana de Medeiros, Louvain, Márcia Costa, Soviero, Vera Ligia Vieira Mendes, Fidalgo, Tatiana Kelly da Silva, Bolan, Michele, Santana, Carla Miranda, Cardoso, Mariane, Mendes, Fausto Medeiros
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/37140
• topic: Tratamento Endodôntico; Dentes Decíduos; Técnica de não instrumentação; Pasta CTZ; Pulpectomia.; Tratamiento Endodóntico; Dientes primarios; Técnica de no instrumentación; Pasta CTZ; Pulpectomía.; Endodontic Treatment; Primary Teeth; Non-instrumentation technique; CTZ paste; Pulpectomy.

Objective: There is a lack of high-quality evidence on the efficacy of the non-instrumentation endodontic treatment (NIET) in primary molars, compared to the conventional endodontic treatment technique. This protocol describes a multicenter randomized clinical trial that aims to evaluate the efficacy of a NIET technique for primary molars using a paste containing antibiotics (chloramphenicol and tetracycline – CTZ group) compared to a control group of conventional technique and root filling with zinc oxide eugenol (ZOE). Methodology: Children aged 3 to 9 years (N=218) will be randomly allocated to one of the groups: CTZ or ZOE. In CTZ, after the location of root canals entrance, irrigation will be performed using 1% sodium hypochlorite and CTZ paste will be placed over the root canal entrances, with no instrumentation of the root canals. In ZOE group, manual instrumentation of root canals with endodontic K-files will be performed, and then, the root canals will be filled with ZOE paste. At the same appointment, teeth will be restored with a double-seal of glass ionomer and a bulk fill resin composite. Children will be followed-up for 6, 12, 18 and 24 months. The primary endpoint will be the success of endodontic treatments evaluated by clinical and radiographic criteria after 24 months. Conclusions: NIET with CTZ paste could be an option to manage primary teeth, once the technique could have non-inferior efficacy to the conventional technique that involves root canal instrumentation. The approach could have good acceptance from children and parents considering the reduced clinical time.