Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activity
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/15436 |
Resumo: | Acquired Immunodeficiency Syndrome (AIDS) is a disease caused by the Human Immunodeficiency Virus (HIV) that attacks the individual's defense cells, the TCD4 + lymphocytes causing a serious immune system disorder. Its treatment is based on therapy combined with antiretroviral medications that manage to control viral load and decrease the mortality rates of the disease. As an alternative, intervention strategies through the practice of physical exercises in order to assist in the treatment and quality of life of people living with HIV have been used for health benefits. This study aims to compare the heart rate variability (HRV) measured by a cardiofrequency meter, in HIV positive patients undergoing antiretroviral therapy (ART) at rest and after performing concurrent training (CT). The present study consists of an analytical, observational and cross-sectional research. The sample will consist of 15 people living with HIV and who are undergoing outpatient clinical follow-up at the Specialized Care Service (SAE) (Casa Rosa) in Barretos, in the interior of the state of São Paulo. To present the data, the Wilcoxon test was used to find which ones were different, the level of significance adopted was p <0.05. To verify the relationship of the results, Spearman's correlation coefficient test was used. The effect size was also calculated using the Cohen test (d). The analyzed data correlated the level of significance in all variables in the frequency and time domain, except for SDNN and SD2. There was a large effect size only for the parameter HF (Δ% = 279.92% reduction) in the frequency domain and in the parameters RMSSD (Δ% = 79.58% reduction) and SD1 (Δ% = 79.62% reduction) in the time domain in the TC, in the other parameters there was no great effect. Thus, one observes that the vagal resumption, which normally occurs after physical training, has not occurred or is returning slowly. While in the LF parameter there was a significant reduction, that is, a sympathetic withdrawal after the CT, even so, the sympathetic withdrawal was not total, since the parameter LF / HF (Δ% = 42.31% increase and TE = 0.70 ), that its increase means sympathetic activity, showed a significant increase after CT. In conclusion, the heart rate variability of the patients under study decreased after concurrent training, possibly due to the autonomic dysfunction shown in the literature for people living with HIV. |
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Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activityAnálisis de la variabilidad de la frecuencia cardíaca en personas que viven con el VIH que reciben terapia antirretroviral (TAR) después de la actividad físicaAnálise da variabilidade da frequência cardíaca em pessoas vivendo com HIV submetidos à terapia antirretroviral (TARV) após a prática de atividade físicaPhysical exerciseHeart rateAIDS serodiagnosisHighly active antiretroviral therapy.Ejercicio físicoFrecuencia cardiacaSerodiagnóstico del SIDATerapia antirretroviral de gran actividad.Exercício físicoFrequência cardíacaSorodiagnóstico da AIDSTerapia Antirretroviral de Alta atividade.Acquired Immunodeficiency Syndrome (AIDS) is a disease caused by the Human Immunodeficiency Virus (HIV) that attacks the individual's defense cells, the TCD4 + lymphocytes causing a serious immune system disorder. Its treatment is based on therapy combined with antiretroviral medications that manage to control viral load and decrease the mortality rates of the disease. As an alternative, intervention strategies through the practice of physical exercises in order to assist in the treatment and quality of life of people living with HIV have been used for health benefits. This study aims to compare the heart rate variability (HRV) measured by a cardiofrequency meter, in HIV positive patients undergoing antiretroviral therapy (ART) at rest and after performing concurrent training (CT). The present study consists of an analytical, observational and cross-sectional research. The sample will consist of 15 people living with HIV and who are undergoing outpatient clinical follow-up at the Specialized Care Service (SAE) (Casa Rosa) in Barretos, in the interior of the state of São Paulo. To present the data, the Wilcoxon test was used to find which ones were different, the level of significance adopted was p <0.05. To verify the relationship of the results, Spearman's correlation coefficient test was used. The effect size was also calculated using the Cohen test (d). The analyzed data correlated the level of significance in all variables in the frequency and time domain, except for SDNN and SD2. There was a large effect size only for the parameter HF (Δ% = 279.92% reduction) in the frequency domain and in the parameters RMSSD (Δ% = 79.58% reduction) and SD1 (Δ% = 79.62% reduction) in the time domain in the TC, in the other parameters there was no great effect. Thus, one observes that the vagal resumption, which normally occurs after physical training, has not occurred or is returning slowly. While in the LF parameter there was a significant reduction, that is, a sympathetic withdrawal after the CT, even so, the sympathetic withdrawal was not total, since the parameter LF / HF (Δ% = 42.31% increase and TE = 0.70 ), that its increase means sympathetic activity, showed a significant increase after CT. In conclusion, the heart rate variability of the patients under study decreased after concurrent training, possibly due to the autonomic dysfunction shown in the literature for people living with HIV.El Síndrome de Inmunodeficiencia Adquirida (SIDA) es una enfermedad causada por el Virus de Inmunodeficiencia Humana (VIH) que ataca las células de defensa del individuo, los linfocitos TCD4 + causando un trastorno grave del sistema inmunológico. Su tratamiento se basa en terapia combinada con medicamentos antirretrovirales que logran controlar la carga viral y disminuir las tasas de mortalidad de la enfermedad. Como alternativa, las estrategias de intervención a través de la práctica de ejercicios físicos para ayudar en el tratamiento y la calidad de vida de las personas que viven con el VIH se han utilizado para obtener beneficios para la salud. Este estudio tiene como objetivo comparar la variabilidad de la frecuencia cardíaca (VFC) medida con un medidor de cardiofrecuencia, en pacientes VIH positivos sometidos a terapia antirretroviral (TAR) en reposo y después de realizar entrenamiento concurrente (TC). El presente estudio consiste en una investigación analítica, observacional y transversal. La muestra estará compuesta por 15 personas que viven con el VIH y que se encuentran en seguimiento clínico ambulatorio en el Servicio de Atención Especializada (SAE) (Casa Rosa) en Barretos, en el interior del estado de São Paulo. Para presentar los datos se utilizó la prueba de Wilcoxon para encontrar cuáles eran diferentes, el nivel de significancia adoptado fue p <0.05. Para verificar la relación de los resultados se utilizó la prueba del coeficiente de correlación de Spearman. El tamaño del efecto también se calculó mediante la prueba de Cohen (d). Los datos analizados correlacionaron el nivel de significancia en todas las variables en el dominio de la frecuencia y el tiempo, excepto para SDNN y SD2. Hubo un gran tamaño del efecto solo para el parámetro HF (Δ% = reducción del 279,92%) en el dominio de la frecuencia y en los parámetros RMSSD (Δ% = reducción del 79,58%) y SD1 (Δ% = reducción del 79,62%) en el dominio del tiempo en el TC, en el resto de parámetros no hubo gran efecto. Así, se observa que la reanudación vagal, que normalmente ocurre después del entrenamiento físico, no se ha producido o está regresando lentamente. Mientras que en el parámetro LF hubo una reducción significativa, es decir, una retirada simpática tras el TC, aun así, la retirada simpática no fue total, ya que el parámetro LF / HF (Δ% = 42,31% de aumento y TE = 0,70), que su aumento significa actividad simpática, mostró un aumento significativo después de la TC. En conclusión, la variabilidad de la frecuencia cardíaca de los pacientes en estudio disminuyó después del entrenamiento concurrente, posiblemente debido a la disfunción autonómica mostrada en la literatura para personas que viven con el VIH.A Síndrome da Imunodeficiência Adquirida (AIDS) é uma doença causada pelo vírus da Imunodeficiência Humana (HIV) que ataca as células de defesa do indivíduo, os linfócitos TCD4+ causando um distúrbio grave do sistema imunológico. Seu tratamento é baseado em terapia combinada com medicações antirretrovirais que conseguem controlar a carga viral e diminuir as taxas de mortalidade da doença. Como alternativa, estratégias de intervenção através da prática de exercícios físicos com a finalidade de auxiliar no tratamento e qualidade de vida de pessoas vivendo com HIV vem sendo utilizadas pelos benefícios à saúde. Este estudo tem como objetivo comparar a variabilidade da frequência cardíaca (VFC) medida por um cardiofrequêncímetro, em pacientes HIV positivos submetidos a terapia antirretroviral (TARV) em repouso e após a realização de um treinamento concorrente (TC). O presente estudo constitui-se de uma pesquisa analítica, observacional e transversal. A amostra será composta por 15 pessoas que vivem com HIV e que se encontram em acompanhamento clínico ambulatorial do Serviço de Atendimento Especializado (SAE) (Casa Rosa) em Barretos interior do estado de São Paulo. Para apresentação dos dados foi utilizado o teste de Wilcoxon para encontrar quais foram diferentes, o nível de significância adotado foi de p<0,05. Para verificar a relação dos resultados, foi utilizado o teste coeficiente de correlação de Spearman. O tamanho de efeito também foi calculado utilizando o teste de Cohen (d). Os dados analisados correlacionaram nível de significância em todas as variáveis no domínio da frequência e do tempo, excetuando SDNN e SD2. Houve tamanho de efeito grande somente para o parâmetro HF (Δ% = 279,92% de redução) no domínio da frequência e nos parâmetros RMSSD (Δ% = 79,58% de redução) e SD1 (Δ% = 79,62% de redução) no domínio do tempo no TC, nos outros parâmetros não houve efeito grande. Dessa forma, observa-se um que a retomada vagal, que normalmente ocorre após um treinamento físico, não ocorreu ou está retornando lentamente. Enquanto no parâmetro LF houve uma redução significativa, ou seja, uma retirada simpática após o TC, mesmo assim a retirada simpática não foi total, pois o parâmetro LF/HF (Δ% = 42,31% de aumento e TE = 0,70), que seu aumento significa atividade simpática, mostrou um aumento significativo após o TC. Em conclusão a variabilidade da frequência cardíaca dos pacientes em estudo diminuiu após o treinamento concorrente possivelmente pela disfunção autonômica evidenciada na literatura para pessoas vivendo com HIV.Research, Society and Development2021-05-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1543610.33448/rsd-v10i6.15436Research, Society and Development; Vol. 10 No. 6; e0610615436Research, Society and Development; Vol. 10 Núm. 6; e0610615436Research, Society and Development; v. 10 n. 6; e06106154362525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/15436/13771Copyright (c) 2021 Tayná Oliveira de Gois ; Cristiane Kelly Aquino dos Santos; Júlio César Camargo Alves; Estelio Henrique Martin Dantas https://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGois , Tayná Oliveira deSantos, Cristiane Kelly Aquino dosAlves, Júlio César CamargoDantas , Estelio Henrique Martin2021-06-10T22:51:46Zoai:ojs.pkp.sfu.ca:article/15436Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:36:15.620074Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activity Análisis de la variabilidad de la frecuencia cardíaca en personas que viven con el VIH que reciben terapia antirretroviral (TAR) después de la actividad física Análise da variabilidade da frequência cardíaca em pessoas vivendo com HIV submetidos à terapia antirretroviral (TARV) após a prática de atividade física |
title |
Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activity |
spellingShingle |
Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activity Gois , Tayná Oliveira de Physical exercise Heart rate AIDS serodiagnosis Highly active antiretroviral therapy. Ejercicio físico Frecuencia cardiaca Serodiagnóstico del SIDA Terapia antirretroviral de gran actividad. Exercício físico Frequência cardíaca Sorodiagnóstico da AIDS Terapia Antirretroviral de Alta atividade. |
title_short |
Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activity |
title_full |
Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activity |
title_fullStr |
Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activity |
title_full_unstemmed |
Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activity |
title_sort |
Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activity |
author |
Gois , Tayná Oliveira de |
author_facet |
Gois , Tayná Oliveira de Santos, Cristiane Kelly Aquino dos Alves, Júlio César Camargo Dantas , Estelio Henrique Martin |
author_role |
author |
author2 |
Santos, Cristiane Kelly Aquino dos Alves, Júlio César Camargo Dantas , Estelio Henrique Martin |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Gois , Tayná Oliveira de Santos, Cristiane Kelly Aquino dos Alves, Júlio César Camargo Dantas , Estelio Henrique Martin |
dc.subject.por.fl_str_mv |
Physical exercise Heart rate AIDS serodiagnosis Highly active antiretroviral therapy. Ejercicio físico Frecuencia cardiaca Serodiagnóstico del SIDA Terapia antirretroviral de gran actividad. Exercício físico Frequência cardíaca Sorodiagnóstico da AIDS Terapia Antirretroviral de Alta atividade. |
topic |
Physical exercise Heart rate AIDS serodiagnosis Highly active antiretroviral therapy. Ejercicio físico Frecuencia cardiaca Serodiagnóstico del SIDA Terapia antirretroviral de gran actividad. Exercício físico Frequência cardíaca Sorodiagnóstico da AIDS Terapia Antirretroviral de Alta atividade. |
description |
Acquired Immunodeficiency Syndrome (AIDS) is a disease caused by the Human Immunodeficiency Virus (HIV) that attacks the individual's defense cells, the TCD4 + lymphocytes causing a serious immune system disorder. Its treatment is based on therapy combined with antiretroviral medications that manage to control viral load and decrease the mortality rates of the disease. As an alternative, intervention strategies through the practice of physical exercises in order to assist in the treatment and quality of life of people living with HIV have been used for health benefits. This study aims to compare the heart rate variability (HRV) measured by a cardiofrequency meter, in HIV positive patients undergoing antiretroviral therapy (ART) at rest and after performing concurrent training (CT). The present study consists of an analytical, observational and cross-sectional research. The sample will consist of 15 people living with HIV and who are undergoing outpatient clinical follow-up at the Specialized Care Service (SAE) (Casa Rosa) in Barretos, in the interior of the state of São Paulo. To present the data, the Wilcoxon test was used to find which ones were different, the level of significance adopted was p <0.05. To verify the relationship of the results, Spearman's correlation coefficient test was used. The effect size was also calculated using the Cohen test (d). The analyzed data correlated the level of significance in all variables in the frequency and time domain, except for SDNN and SD2. There was a large effect size only for the parameter HF (Δ% = 279.92% reduction) in the frequency domain and in the parameters RMSSD (Δ% = 79.58% reduction) and SD1 (Δ% = 79.62% reduction) in the time domain in the TC, in the other parameters there was no great effect. Thus, one observes that the vagal resumption, which normally occurs after physical training, has not occurred or is returning slowly. While in the LF parameter there was a significant reduction, that is, a sympathetic withdrawal after the CT, even so, the sympathetic withdrawal was not total, since the parameter LF / HF (Δ% = 42.31% increase and TE = 0.70 ), that its increase means sympathetic activity, showed a significant increase after CT. In conclusion, the heart rate variability of the patients under study decreased after concurrent training, possibly due to the autonomic dysfunction shown in the literature for people living with HIV. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-05-18 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/15436 10.33448/rsd-v10i6.15436 |
url |
https://rsdjournal.org/index.php/rsd/article/view/15436 |
identifier_str_mv |
10.33448/rsd-v10i6.15436 |
dc.language.iso.fl_str_mv |
por |
language |
por |
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https://rsdjournal.org/index.php/rsd/article/view/15436/13771 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 6; e0610615436 Research, Society and Development; Vol. 10 Núm. 6; e0610615436 Research, Society and Development; v. 10 n. 6; e0610615436 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
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UNIFEI |
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UNIFEI |
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Research, Society and Development |
collection |
Research, Society and Development |
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Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
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rsd.articles@gmail.com |
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1797052677550505984 |