Effectiveness of medicinal plants extracts in the in vitro control of Candida albicans

Detalhes bibliográficos
Autor(a) principal: Estruzani, Taina
Data de Publicação: 2022
Outros Autores: Kozusny-Andreani, Dora Inés
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/26779
Resumo: Fungal diseases after diagnosis are treated with different antimicrobial agents, however, resistant strains have appeared. Faced with the emergence of Candida strains resistant to synthetic antifungal agents, it was observed that the use of medicinal plants capable of inhibiting the growth of these microorganisms has been the subject of studies. Thus, scientific investigation of the properties of essential oils and plant extracts has been carried out in search of an equivalent satisfactory level and a lower rate of disadvantages or side effects. The objective was to evaluate the effectiveness of plant extracts in inhibiting the growth of Candida albicans. Three clinical strains of C. albicans and standard C. albicans ATCC 25923 were used. To obtain the extracts rue, rosemary, neem and citronella leaves were used. Hydroalcoholic extraction was carried out in 70% ethanol. Minimum inhibitory concentration (MIC), minimum fungicidal concentration (MFC) and viability against the different extracts were determined. C. albicans ATCC 25923 strains and clinics showed susceptibility to the different extracts. The extracts showed the ability to cancel the growth of C. albicans at different times, however they showed efficacy in the control this yeast.The results obtained reveal that rosemary, rue, citronella and neem plants can be a potential source of new antifungal agents for the control of Candida albicans.
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spelling Effectiveness of medicinal plants extracts in the in vitro control of Candida albicansEficacia de extractos de plantas medicinales en el control in vitro de Candida albicansEficácia de extratos plantas medicinais no controle in vitro de Candida albicansAntifungal activityRuta graveolensRosmarinus officinalisAzadirachta indicaCymbopogon nardus.Actividad antifúngicaRuta graveolensRosmarinus officinalisAzadirachta indicaCymbopogon nardus.Atividade antifúngicaRuta graveolensRosmarinus officinalisAzadirachta indicaCymbopogon nardus.Fungal diseases after diagnosis are treated with different antimicrobial agents, however, resistant strains have appeared. Faced with the emergence of Candida strains resistant to synthetic antifungal agents, it was observed that the use of medicinal plants capable of inhibiting the growth of these microorganisms has been the subject of studies. Thus, scientific investigation of the properties of essential oils and plant extracts has been carried out in search of an equivalent satisfactory level and a lower rate of disadvantages or side effects. The objective was to evaluate the effectiveness of plant extracts in inhibiting the growth of Candida albicans. Three clinical strains of C. albicans and standard C. albicans ATCC 25923 were used. To obtain the extracts rue, rosemary, neem and citronella leaves were used. Hydroalcoholic extraction was carried out in 70% ethanol. Minimum inhibitory concentration (MIC), minimum fungicidal concentration (MFC) and viability against the different extracts were determined. C. albicans ATCC 25923 strains and clinics showed susceptibility to the different extracts. The extracts showed the ability to cancel the growth of C. albicans at different times, however they showed efficacy in the control this yeast.The results obtained reveal that rosemary, rue, citronella and neem plants can be a potential source of new antifungal agents for the control of Candida albicans.Las enfermedades fúngicas después del diagnóstico son tratadas con diferentes agentes antimicrobianos, sin embargo, han aparecido cepas resistentes. Ante la aparición de cepas de Candida resistentes a los antifúngicos sintéticos, se observó que el uso de plantas medicinales capaces de inhibir el crecimiento de estos microorganismos ha sido objeto de estudios. Así, se ha llevado a cabo una investigación científica de las propiedades de los aceites esenciales y extractos de plantas en busca de un nivel satisfactorio equivalente y un índice menor de inconvenientes o efectos secundarios. El objetivo fue evaluar la efectividad de los extractos de plantas para inhibir el crecimiento de C. albicans. Se utilizaron tres cepas clínicas de C. albicans y C. albicans estándar ATCC 25923. Para la obtención de los extractos se utilizaron hojas de ruda, romero, neem y citronela. La extracción hidroalcohólica se realizó en etanol al 70%. Se determinó la concentración mínima inhibitoria (MIC), la concentración mínima fungicida (MFC) y la viabilidad frente a los diferentes extractos. Las cepas clínicas de C. albicans y estándar ATCC 25923 mostraron susceptibilidad a los diferentes extractos. Los extractos mostraron la capacidad de cancelar el crecimiento de C. albicans en diferentes momentos, sin embargo, mostraron efectividad en el control de esta levadura. Los resultados obtenidos revelan que las plantas de romero, ruda, citronela y neem pueden ser una fuente potencial de nuevos agentes antifúngicos para el control de C. albicans.As doenças fúngicas após diagnóstico são tratadas com diferentes agentes antimicrobianos, no entanto, tem ocorrido o aparecimento de cepas resistentes. Frente ao surgimento de cepas de Candida resistentes aos antifúngicos sintéticos, observou-se que o emprego de plantas medicinais com capacidade de inibir o crescimento destes microrganismos tem sido alvo de estudos. Assim, a investigação científica das propriedades dos óleos essenciais e dos extratos de plantas tem sido realizada na busca de um nível satisfatório equivalente e menor índice de desvantagens ou efeitos colaterais. Objetivou-se avaliar a eficácia de extratos vegetais na inibição do crescimento de C. albicans. Foram utilizadas três linhagens clinicas de C. albicans e padrão C. albicans ATCC 25923. Para obtenção dos extratos empregaram-se folhas de arruda, alecrim, nim e citronela. Realizou-se extração hidroalcóolica em etanol 70%. Foram determinadas a concentração inibitória mínima (CIM), concentração fungicida mínima (CFM) e a viabilidade frente aos diferentes extratos. As linhagens de C. albicans ATCC 25923 e as clínicas apresentaram suscetibilidade a os diferentes extratos. Os extratos evidenciaram a capacidade de anular o crescimento de C. albicans em diferentes tempos, no entanto exibiram eficácia no controle desta levedura. Os resultados obtidos revelam que as plantas de alecrim, arruda, citronela e nim podem ser uma fonte potencial de novos agentes antifúngicos para o controle de C. albicans.Research, Society and Development2022-03-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2677910.33448/rsd-v11i3.26779Research, Society and Development; Vol. 11 No. 3; e53311326779Research, Society and Development; Vol. 11 Núm. 3; e53311326779Research, Society and Development; v. 11 n. 3; e533113267792525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/26779/23514Copyright (c) 2022 Taina Estruzani; Dora Inés Kozusny-Andreanihttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessEstruzani, Taina Kozusny-Andreani, Dora Inés2022-03-09T13:44:38Zoai:ojs.pkp.sfu.ca:article/26779Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:44.143174Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Effectiveness of medicinal plants extracts in the in vitro control of Candida albicans
Eficacia de extractos de plantas medicinales en el control in vitro de Candida albicans
Eficácia de extratos plantas medicinais no controle in vitro de Candida albicans
title Effectiveness of medicinal plants extracts in the in vitro control of Candida albicans
spellingShingle Effectiveness of medicinal plants extracts in the in vitro control of Candida albicans
Estruzani, Taina
Antifungal activity
Ruta graveolens
Rosmarinus officinalis
Azadirachta indica
Cymbopogon nardus.
Actividad antifúngica
Ruta graveolens
Rosmarinus officinalis
Azadirachta indica
Cymbopogon nardus.
Atividade antifúngica
Ruta graveolens
Rosmarinus officinalis
Azadirachta indica
Cymbopogon nardus.
title_short Effectiveness of medicinal plants extracts in the in vitro control of Candida albicans
title_full Effectiveness of medicinal plants extracts in the in vitro control of Candida albicans
title_fullStr Effectiveness of medicinal plants extracts in the in vitro control of Candida albicans
title_full_unstemmed Effectiveness of medicinal plants extracts in the in vitro control of Candida albicans
title_sort Effectiveness of medicinal plants extracts in the in vitro control of Candida albicans
author Estruzani, Taina
author_facet Estruzani, Taina
Kozusny-Andreani, Dora Inés
author_role author
author2 Kozusny-Andreani, Dora Inés
author2_role author
dc.contributor.author.fl_str_mv Estruzani, Taina
Kozusny-Andreani, Dora Inés
dc.subject.por.fl_str_mv Antifungal activity
Ruta graveolens
Rosmarinus officinalis
Azadirachta indica
Cymbopogon nardus.
Actividad antifúngica
Ruta graveolens
Rosmarinus officinalis
Azadirachta indica
Cymbopogon nardus.
Atividade antifúngica
Ruta graveolens
Rosmarinus officinalis
Azadirachta indica
Cymbopogon nardus.
topic Antifungal activity
Ruta graveolens
Rosmarinus officinalis
Azadirachta indica
Cymbopogon nardus.
Actividad antifúngica
Ruta graveolens
Rosmarinus officinalis
Azadirachta indica
Cymbopogon nardus.
Atividade antifúngica
Ruta graveolens
Rosmarinus officinalis
Azadirachta indica
Cymbopogon nardus.
description Fungal diseases after diagnosis are treated with different antimicrobial agents, however, resistant strains have appeared. Faced with the emergence of Candida strains resistant to synthetic antifungal agents, it was observed that the use of medicinal plants capable of inhibiting the growth of these microorganisms has been the subject of studies. Thus, scientific investigation of the properties of essential oils and plant extracts has been carried out in search of an equivalent satisfactory level and a lower rate of disadvantages or side effects. The objective was to evaluate the effectiveness of plant extracts in inhibiting the growth of Candida albicans. Three clinical strains of C. albicans and standard C. albicans ATCC 25923 were used. To obtain the extracts rue, rosemary, neem and citronella leaves were used. Hydroalcoholic extraction was carried out in 70% ethanol. Minimum inhibitory concentration (MIC), minimum fungicidal concentration (MFC) and viability against the different extracts were determined. C. albicans ATCC 25923 strains and clinics showed susceptibility to the different extracts. The extracts showed the ability to cancel the growth of C. albicans at different times, however they showed efficacy in the control this yeast.The results obtained reveal that rosemary, rue, citronella and neem plants can be a potential source of new antifungal agents for the control of Candida albicans.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-07
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/26779
10.33448/rsd-v11i3.26779
url https://rsdjournal.org/index.php/rsd/article/view/26779
identifier_str_mv 10.33448/rsd-v11i3.26779
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/26779/23514
dc.rights.driver.fl_str_mv Copyright (c) 2022 Taina Estruzani; Dora Inés Kozusny-Andreani
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2022 Taina Estruzani; Dora Inés Kozusny-Andreani
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 3; e53311326779
Research, Society and Development; Vol. 11 Núm. 3; e53311326779
Research, Society and Development; v. 11 n. 3; e53311326779
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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