Combined vitamin C and E supplementation for disease risk reduction
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/6088 |
Resumo: | This review aimed to compile the results of combined use of vitamin C and E supplementation, their antioxidant effects applied in general diseases, researched in the past years and compare such dosages with the ones separately recommended in Normative Instruction nº 28 published on June of 2018 by the Brazilian National Health Surveillance Agency (ANVISA). Bibliographic research was performed in three databases on combined supplementation and the synergistic relationship between vitamins C and E. The dosages used by the researchers were tabulated for better understanding and the results were discussed and compared against the recommendations established by ANVISA low. In conclusion, when the maximum and minimum daily intake levels of vitamins C and E was drafted in the legislation, according to the population subgroups, ANVISA defined criteria for the designation of antioxidant bioactive compounds and regulated the possibility of combined supplementation of these compounds in reducing the risk of disease through oxidative stress. On the other hand, on the researcher and / or health professional falls the responsibility to previously define the supplementation protocol, considering the synergistic relationship of the constituents and avoiding the generation of pro-oxidant effects, which possibly tends to result in an adverse effect to the desired one. |
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Combined vitamin C and E supplementation for disease risk reductionSuplementación combinada de vitamina C y E para reducir el riesgo de enfermedadesSuplementação combinadas de vitaminas C e E com objetivo de redução do risco de doençasAntioxidante; Sustancia bioactiva; Agencia Nacional de Vigilancia Sanitaria.Antioxidant; Bioactive substances; National Health Surveillance Agency. Antioxidante; Substancia bioativa; ANVISA. This review aimed to compile the results of combined use of vitamin C and E supplementation, their antioxidant effects applied in general diseases, researched in the past years and compare such dosages with the ones separately recommended in Normative Instruction nº 28 published on June of 2018 by the Brazilian National Health Surveillance Agency (ANVISA). Bibliographic research was performed in three databases on combined supplementation and the synergistic relationship between vitamins C and E. The dosages used by the researchers were tabulated for better understanding and the results were discussed and compared against the recommendations established by ANVISA low. In conclusion, when the maximum and minimum daily intake levels of vitamins C and E was drafted in the legislation, according to the population subgroups, ANVISA defined criteria for the designation of antioxidant bioactive compounds and regulated the possibility of combined supplementation of these compounds in reducing the risk of disease through oxidative stress. On the other hand, on the researcher and / or health professional falls the responsibility to previously define the supplementation protocol, considering the synergistic relationship of the constituents and avoiding the generation of pro-oxidant effects, which possibly tends to result in an adverse effect to the desired one.Esta revisión tuvo como objetivo recopilar los resultados del uso de la suplementación combinada de vitaminas C y E, sus efectos antioxidantes aplicados en enfermedades en general, investigados en los últimos años y comparar con las dosis recomendadas por ANVISA, por separado, publicadas en la Instrucción Normativa nº 28 de junio. / 2018. La investigación bibliográfica se realizó en 2 bases de datos sobre la suplementación combinada y la relación sinérgica entre las vitaminas C y E. Se tabularon las dosis utilizadas por los investigadores para una mejor comprensión y los resultados encontrados se discutieron y compararon con las recomendaciones establecidas por esta institución. . En conclusión, al redactar la legislación con los límites máximos y mínimos de ingesta diaria de vitaminas C y E, según subgrupos poblacionales, ANVISA definió los criterios para la designación de compuestos bioactivos antioxidantes y regularizó la posibilidad de suplementación combinada de estos compuestos en Reducir el riesgo de enfermedades por estrés oxidativo. Por otro lado, es responsabilidad del investigador y / o profesional de la salud definir con anticipación el protocolo de suplementación, considerando la relación sinérgica de los constituyentes evitando la generación de efectos pro-oxidantes, que posiblemente tiendan a resultar en un efecto adverso al deseado.Esta revisão objetivou compilar os resultados da utilização da suplementação combinada de vitaminas C e E, seus efeitos antioxidantes aplicados em doenças em geral, pesquisados nos últimos anos e comparar com as dosagens recomendadas pela ANVISA, de forma separadamente, publicadas na Instrução Normativa nº28 de Junho/2018. Foi realizado pesquisa bibliográfica em 2 bases de dados sobre a suplementação combinada e a relação sinérgica existente entre as vitaminas C e E. As dosagens utilizadas pelos pesquisadores foram tabuladas para melhor compreensão e os resultados encontrados foram discutidos e comparados com as recomendações estabelecidas por esta instituição. Conclui-se, que ao elaborar uma legislação com os limites máximos e mínimos de ingestão diária de vitaminas C e E, conforme os subgrupos populacionais, a ANVISA definiu os critérios da designação dos compostos bioativos antioxidantes e regularizou a possibilidade de suplementação combinada destes compostos na redução do risco de doenças por meio do estresse oxidativo. Por outro lado, é responsabilidade do pesquisador e/ou profissional de saúde definir previamente o protocolo de suplementação, considerando a relação sinérgica dos constituintes evitando a geração de efeitos pró-oxidantes, o que possivelmente tende a resultar em efeito adverso ao desejado.Research, Society and Development2020-08-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/608810.33448/rsd-v9i9.6088Research, Society and Development; Vol. 9 No. 9; e603996088Research, Society and Development; Vol. 9 Núm. 9; e603996088Research, Society and Development; v. 9 n. 9; e6039960882525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/6088/6801Copyright (c) 2020 Isaac Dias Bezerra, Geovana Rocha Plácido, Rogério Favareto, Mayra Conceição Martins Peixoto, Raissa de Melo Matos Ferreira, Lilianne Baldoino Monteiro, Itatiane Catarina Guerra, Erica de Freitas Cabralhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBezerra, Isaac DiasFerreira, Raissa de Melo MatosPeixoto, Mayra Conceição MartinsPlácido, Geovana RochaFavareto, RogérioMonteiro, Lilianne BaldoinoCabral, Erica de FreitasGuerra, Itatiane Catarina2020-09-18T01:42:11Zoai:ojs.pkp.sfu.ca:article/6088Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:29:21.501655Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Combined vitamin C and E supplementation for disease risk reduction Suplementación combinada de vitamina C y E para reducir el riesgo de enfermedades Suplementação combinadas de vitaminas C e E com objetivo de redução do risco de doenças |
title |
Combined vitamin C and E supplementation for disease risk reduction |
spellingShingle |
Combined vitamin C and E supplementation for disease risk reduction Bezerra, Isaac Dias Antioxidante; Sustancia bioactiva; Agencia Nacional de Vigilancia Sanitaria. Antioxidant; Bioactive substances; National Health Surveillance Agency. Antioxidante; Substancia bioativa; ANVISA. |
title_short |
Combined vitamin C and E supplementation for disease risk reduction |
title_full |
Combined vitamin C and E supplementation for disease risk reduction |
title_fullStr |
Combined vitamin C and E supplementation for disease risk reduction |
title_full_unstemmed |
Combined vitamin C and E supplementation for disease risk reduction |
title_sort |
Combined vitamin C and E supplementation for disease risk reduction |
author |
Bezerra, Isaac Dias |
author_facet |
Bezerra, Isaac Dias Ferreira, Raissa de Melo Matos Peixoto, Mayra Conceição Martins Plácido, Geovana Rocha Favareto, Rogério Monteiro, Lilianne Baldoino Cabral, Erica de Freitas Guerra, Itatiane Catarina |
author_role |
author |
author2 |
Ferreira, Raissa de Melo Matos Peixoto, Mayra Conceição Martins Plácido, Geovana Rocha Favareto, Rogério Monteiro, Lilianne Baldoino Cabral, Erica de Freitas Guerra, Itatiane Catarina |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Bezerra, Isaac Dias Ferreira, Raissa de Melo Matos Peixoto, Mayra Conceição Martins Plácido, Geovana Rocha Favareto, Rogério Monteiro, Lilianne Baldoino Cabral, Erica de Freitas Guerra, Itatiane Catarina |
dc.subject.por.fl_str_mv |
Antioxidante; Sustancia bioactiva; Agencia Nacional de Vigilancia Sanitaria. Antioxidant; Bioactive substances; National Health Surveillance Agency. Antioxidante; Substancia bioativa; ANVISA. |
topic |
Antioxidante; Sustancia bioactiva; Agencia Nacional de Vigilancia Sanitaria. Antioxidant; Bioactive substances; National Health Surveillance Agency. Antioxidante; Substancia bioativa; ANVISA. |
description |
This review aimed to compile the results of combined use of vitamin C and E supplementation, their antioxidant effects applied in general diseases, researched in the past years and compare such dosages with the ones separately recommended in Normative Instruction nº 28 published on June of 2018 by the Brazilian National Health Surveillance Agency (ANVISA). Bibliographic research was performed in three databases on combined supplementation and the synergistic relationship between vitamins C and E. The dosages used by the researchers were tabulated for better understanding and the results were discussed and compared against the recommendations established by ANVISA low. In conclusion, when the maximum and minimum daily intake levels of vitamins C and E was drafted in the legislation, according to the population subgroups, ANVISA defined criteria for the designation of antioxidant bioactive compounds and regulated the possibility of combined supplementation of these compounds in reducing the risk of disease through oxidative stress. On the other hand, on the researcher and / or health professional falls the responsibility to previously define the supplementation protocol, considering the synergistic relationship of the constituents and avoiding the generation of pro-oxidant effects, which possibly tends to result in an adverse effect to the desired one. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-08-31 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/6088 10.33448/rsd-v9i9.6088 |
url |
https://rsdjournal.org/index.php/rsd/article/view/6088 |
identifier_str_mv |
10.33448/rsd-v9i9.6088 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/6088/6801 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 9 No. 9; e603996088 Research, Society and Development; Vol. 9 Núm. 9; e603996088 Research, Society and Development; v. 9 n. 9; e603996088 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052654034092032 |