Association between hypertriglyceridemic waist phenotype and Diabetes mellitus in adults: a case-control study

Detalhes bibliográficos
Autor(a) principal: Wünsch, Caroline
Data de Publicação: 2022
Outros Autores: Zanovello, Syssa Reino, Iahnn, Stephanie Ramirez, Andrade, Gabriela Rieveres Borges de, Lima, Rosangela da Costa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/29328
Resumo: Diabetes mellitus (DM) is considered a major public health problem. Studies in several countries points to the usefulness of evaluating the hypertriglyceridemic waist (HTC) phenotype to predict the risk of the disease. Aim: This study aimed to evaluate the association between the HTC phenotype and DM type 2 in Dourados, MS, Brazil. Methods: This is a case-control study nested within a population-based cross-sectional survey with multiple-stage sampling, carried out in 2016. The sample included 293 adults aged 20 to 59 years, of which 56 were cases and 237 controls. The cases were those with fasting blood glucose ≥ 126mg/dL and who reported that “a doctor or health professional has already said that “Do you have high blood sugar?” Controls were drawn from the other interviewees, without DM. Individuals with waist circumference (WC) were considered to have the HTC phenotype: ≥ 80 cm for women and ≥ 90 cm for men, combined with hypertriglyceridemia (TG) ≥ 150 mg/dL. The variables gender, age, education, socioeconomic status, smoking, alcohol consumption, physical activity and body mass index were investigated. Chi-Square Test, Fisher's Exact Test and Unconditional Logistic Regression were used for data analysis. Results: The HTC phenotype was positively associated with DM: 2.08, 95%CI: 1.04-4.12, after adjusting for covariates. Conclusion: The study suggests that the HTC phenotype may be useful as an approach in the identification of DM.
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spelling Association between hypertriglyceridemic waist phenotype and Diabetes mellitus in adults: a case-control study Asociación entre el fenotipo de cintura hipertrigliceridémica y la Diabetes mellitus en adultos: estudio de casos y controlesAssociação entre o fenótipo cintura hipertrigliceridêmica e o Diabetes mellitus em adultos: um estudo de casos e controlesCintura hipertrigliceridêmicaCircunferência da cinturaDiabetes mellitus.Hypertriglyceridemic waistWaist circumferenceDiabetes mellitus.Cintura hipertrigliceridémicaCircunferencia de la cinturaDiabetes mellitus.Diabetes mellitus (DM) is considered a major public health problem. Studies in several countries points to the usefulness of evaluating the hypertriglyceridemic waist (HTC) phenotype to predict the risk of the disease. Aim: This study aimed to evaluate the association between the HTC phenotype and DM type 2 in Dourados, MS, Brazil. Methods: This is a case-control study nested within a population-based cross-sectional survey with multiple-stage sampling, carried out in 2016. The sample included 293 adults aged 20 to 59 years, of which 56 were cases and 237 controls. The cases were those with fasting blood glucose ≥ 126mg/dL and who reported that “a doctor or health professional has already said that “Do you have high blood sugar?” Controls were drawn from the other interviewees, without DM. Individuals with waist circumference (WC) were considered to have the HTC phenotype: ≥ 80 cm for women and ≥ 90 cm for men, combined with hypertriglyceridemia (TG) ≥ 150 mg/dL. The variables gender, age, education, socioeconomic status, smoking, alcohol consumption, physical activity and body mass index were investigated. Chi-Square Test, Fisher's Exact Test and Unconditional Logistic Regression were used for data analysis. Results: The HTC phenotype was positively associated with DM: 2.08, 95%CI: 1.04-4.12, after adjusting for covariates. Conclusion: The study suggests that the HTC phenotype may be useful as an approach in the identification of DM.La diabetes mellitus (DM) es un grave problema de salud pública. Estudios en varios países apuntan a la utilidad de evaluar el fenotipo de cintura hipertrigliceridémica (CHT) para predecir el riesgo de la enfermedad. Objetivo: Este estudio tuvo como objetivo evaluar la asociación entre el fenotipo HTC y DM tipo 2 en Dourados-MS, Brasil. Métodos: Se trata de un estudio de casos y controles anidado dentro de una encuesta transversal de base poblacional con muestreo polietápico, realizada en 2016. La muestra estuvo compuesta por 293 adultos de 20 a 59 años, de los cuales 56 fueron casos y 237 controles. Los casos fueron aquellos con glucemia en ayunas ≥ 126mg/dL y que reportaron que “algún médico o profesional de la salud ya les dijo que el Sr. ¿Tienes un nivel alto de azúcar en la sangre?” Los controles se extrajeron de los otros entrevistados, sin DM. Se consideró que los individuos con circunferencia de cintura (CC) tenían el fenotipo HTC: ≥ 80 cm para mujeres y ≥ 90 cm para hombres, combinado con hipertrigliceridemia (TG) ≥ 150 mg/dL. Se investigaron las variables sexo, edad, escolaridad, nivel socioeconómico, tabaquismo, consumo de alcohol, actividad física e índice de masa corporal. Para el análisis de los datos se utilizaron la prueba de chi-cuadrado, la prueba exacta de Fisher y la regresión logística incondicional. Resultados: El fenotipo CHT se asoció positivamente con DM: 2,08, IC 95%: 1,04-4,12, después de ajustar por covariables. Conclusión: El estudio sugiere que el fenotipo CHT puede ser útil como abordaje en la identificación de DM.O diabetes mellitus (DM) é um grave problema de saúde pública. Estudos em diversos países apontam a utilidade da avaliação do fenótipo cintura hipertrigliceridêmica (CHT) para prever o risco da doença. Objetivo: Este estudo objetivou avaliar a associação entre o fenótipo CHT e o DM tipo 2 em Dourados-MS, Brasil. Métodos: Trata-se de um estudo de casos e controles aninhado a uma pesquisa transversal de base populacional com amostragem em múltiplos estágios, realizado em 2016. A amostra incluiu 293 adultos de 20 a 59 anos, dos quais 56 casos e 237 controles. Os casos foram aqueles com glicemia de jejum ≥ 126mg/dL e que referiram que “algum médico ou profissional de saúde já disse que o Sr. tem açúcar alto no sangue?”. Os controles foram sorteados dos demais entrevistados, sem DM. Consideraram-se com presença do fenótipo CHT indivíduos que apresentaram circunferência da cintura (CC): ≥ 80 cm para mulheres e ≥ 90 cm para homens, combinada com hipertrigliceridemia (TG) ≥ 150 mg/dL. Foram investigadas as variáveis sexo, idade, escolaridade, estrato socioeconômico, tabagismo, consumo de bebida alcóolica, atividade física e índice de massa corporal. Teste Qui-Quadrado, Teste Exato de Fisher e Regressão Logística Não Condicional foram utilizados para análise dos dados. Resultados: O fenótipo CHT apresentou-se positivamente associado ao DM: 2,08, IC95%: 1,04-4,12, após o ajuste para covariáveis. Conclusão: O estudo sugere que o fenótipo CHT pode ser útil como uma abordagem na identificação do DM.Research, Society and Development2022-05-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2932810.33448/rsd-v11i6.29328Research, Society and Development; Vol. 11 No. 6; e53711629328Research, Society and Development; Vol. 11 Núm. 6; e53711629328Research, Society and Development; v. 11 n. 6; e537116293282525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/29328/25481Copyright (c) 2022 Caroline Wünsch; Syssa Reino Zanovello; Stephanie Ramirez Iahnn; Gabriela Rieveres Borges de Andrade; Rosangela da Costa Limahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessWünsch, Caroline Zanovello, Syssa Reino Iahnn, Stephanie RamirezAndrade, Gabriela Rieveres Borges de Lima, Rosangela da Costa 2022-05-13T18:04:10Zoai:ojs.pkp.sfu.ca:article/29328Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:46:26.762515Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Association between hypertriglyceridemic waist phenotype and Diabetes mellitus in adults: a case-control study
Asociación entre el fenotipo de cintura hipertrigliceridémica y la Diabetes mellitus en adultos: estudio de casos y controles
Associação entre o fenótipo cintura hipertrigliceridêmica e o Diabetes mellitus em adultos: um estudo de casos e controles
title Association between hypertriglyceridemic waist phenotype and Diabetes mellitus in adults: a case-control study
spellingShingle Association between hypertriglyceridemic waist phenotype and Diabetes mellitus in adults: a case-control study
Wünsch, Caroline
Cintura hipertrigliceridêmica
Circunferência da cintura
Diabetes mellitus.
Hypertriglyceridemic waist
Waist circumference
Diabetes mellitus.
Cintura hipertrigliceridémica
Circunferencia de la cintura
Diabetes mellitus.
title_short Association between hypertriglyceridemic waist phenotype and Diabetes mellitus in adults: a case-control study
title_full Association between hypertriglyceridemic waist phenotype and Diabetes mellitus in adults: a case-control study
title_fullStr Association between hypertriglyceridemic waist phenotype and Diabetes mellitus in adults: a case-control study
title_full_unstemmed Association between hypertriglyceridemic waist phenotype and Diabetes mellitus in adults: a case-control study
title_sort Association between hypertriglyceridemic waist phenotype and Diabetes mellitus in adults: a case-control study
author Wünsch, Caroline
author_facet Wünsch, Caroline
Zanovello, Syssa Reino
Iahnn, Stephanie Ramirez
Andrade, Gabriela Rieveres Borges de
Lima, Rosangela da Costa
author_role author
author2 Zanovello, Syssa Reino
Iahnn, Stephanie Ramirez
Andrade, Gabriela Rieveres Borges de
Lima, Rosangela da Costa
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Wünsch, Caroline
Zanovello, Syssa Reino
Iahnn, Stephanie Ramirez
Andrade, Gabriela Rieveres Borges de
Lima, Rosangela da Costa
dc.subject.por.fl_str_mv Cintura hipertrigliceridêmica
Circunferência da cintura
Diabetes mellitus.
Hypertriglyceridemic waist
Waist circumference
Diabetes mellitus.
Cintura hipertrigliceridémica
Circunferencia de la cintura
Diabetes mellitus.
topic Cintura hipertrigliceridêmica
Circunferência da cintura
Diabetes mellitus.
Hypertriglyceridemic waist
Waist circumference
Diabetes mellitus.
Cintura hipertrigliceridémica
Circunferencia de la cintura
Diabetes mellitus.
description Diabetes mellitus (DM) is considered a major public health problem. Studies in several countries points to the usefulness of evaluating the hypertriglyceridemic waist (HTC) phenotype to predict the risk of the disease. Aim: This study aimed to evaluate the association between the HTC phenotype and DM type 2 in Dourados, MS, Brazil. Methods: This is a case-control study nested within a population-based cross-sectional survey with multiple-stage sampling, carried out in 2016. The sample included 293 adults aged 20 to 59 years, of which 56 were cases and 237 controls. The cases were those with fasting blood glucose ≥ 126mg/dL and who reported that “a doctor or health professional has already said that “Do you have high blood sugar?” Controls were drawn from the other interviewees, without DM. Individuals with waist circumference (WC) were considered to have the HTC phenotype: ≥ 80 cm for women and ≥ 90 cm for men, combined with hypertriglyceridemia (TG) ≥ 150 mg/dL. The variables gender, age, education, socioeconomic status, smoking, alcohol consumption, physical activity and body mass index were investigated. Chi-Square Test, Fisher's Exact Test and Unconditional Logistic Regression were used for data analysis. Results: The HTC phenotype was positively associated with DM: 2.08, 95%CI: 1.04-4.12, after adjusting for covariates. Conclusion: The study suggests that the HTC phenotype may be useful as an approach in the identification of DM.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-09
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/29328
10.33448/rsd-v11i6.29328
url https://rsdjournal.org/index.php/rsd/article/view/29328
identifier_str_mv 10.33448/rsd-v11i6.29328
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/29328/25481
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 6; e53711629328
Research, Society and Development; Vol. 11 Núm. 6; e53711629328
Research, Society and Development; v. 11 n. 6; e53711629328
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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