Body fat percentagem and body mass index predispose chronic kidney disease patients to variations on blood biomarkers

• Autor(a) principal: Oliveira, Maria Thairle dos Santos de
• Data de Publicação: 2022
• Outros Autores: Bragança, Maylla Luanna Barbosa Martins, Dias, Raimunda Sheyla Carneiro, Carneiro, Erika Cristina Ribeiro de Lima, Santos, Elisangela Milhomem, França, Ana Karina Teixeira Cunha, Furtado, Elane Viana Hortegal, Matos, Heulenmacya Rodrigues de, Salgado Filho, Natalino, Bernardo-Filho, Mário
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/33207
• topic: Chronic Kidney Disease; Body Mass Index; Adiposity; Biomarkers.; Enfermedad Renal Crónica; Índice de Masa Corporal; Adiposidad; Biomarcadores.; Doença Renal Crônica; Índice de Massa Corporal; Adiposidade; Biomarcadores.

Objective: To analyze variations of biomarkers with different body mass index (BMI) and body fat percentage (% BF). Methods: Cross-sectional study, comprising 173 patients with CKD. Twenty blood biomarkers were evaluated. BMI was categorized as eutrophic and overweight. % BF was assessed by air displacement plethysmography and rated high when ≥25% for men and ≥32% for women. Four groups were categorized: eutrophic (adequate BMI and % BF), normal-weight obese (adequate BMI and high % BF), overweight and adequate % BG (high BMI and normal % BF) and real obese (BMI and% BF high). Results: Compared to eutrophic individuals, the “normal-weight obese” registered lower hemoglobin (12.5 mg / dl) and hematocrit (37.0%), higher values for phosphorus (3.6 mg / dl), CRP (0.2 mg / dL) and fasting blood glucose (105.5 mg / dL). The “real obese” had lower creatinine (1.6 mg / dL) and higher triglycerides (159 mg / dL), CRP (0.3 mg / dL) and fasting glucose (101 mg/dL). The group “overweight and adequate% BF” showed higher triglycerides (217 mg / dL) blood glucose (108mg / dL) and lower HDL-c (33.9 mg / dL). Conclusions: The “obese of normal weight” showed more variations on the biomarkers. The “overweight and adequate% BF” and “real obese” groups had higher serum values for some parameters. The need to assess combined parameters is emphasized, as both BMI and% BF can influence biochemical markers.