A randomized study comparing the effect of platelet-rich plasma and platelet-poor plasma for the treatment of plantar fasciitis
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/43168 |
Resumo: | Objective: To verify the effectiveness of therapy with platelet-rich plasma (PRP) in patients with plantar fasciitis, this prospective, longitudinal, double-blind study was carried out. Methodology: Twenty-three participants with chronic plantar fasciitis aged > 20 years, already treated with conventional methods were included. Participants were randomly divided into platelet-poor plasma (PPP) and platelet-rich plasma (PRP) groups. Double centrifugation was carried out to prepare the platelets samples and two millilitres of PPP (supernatant fraction) or PRP (sediment fraction) were mixed with 1mL of 2% calcium gluconate solution and injected in the plantar fascia, as a single dose. A follow-up at 15 days and then every 60 days up to 180 days of application was carried out and a visual analogue scale (VAS) for pain assessment and the quality-of-life scale validated by the American Orthopedic Foot and Ankle Society (AOFAS) were used to measure the outcomes. Results: A reduction in pain (VAS 8 to 4), in both groups, was seen in the first 15 days and remained up to the 6th month after the application of plasmas, however, no difference was observed between the groups. No significant improvement was observed in the quality of life of the patients. Conclusion: PPP or PRP were able to reduce the VAS, but the presence of platelets did not have a role in the pain relief. Other factors in the plasma may play a role in reducing the pain caused by plantar fasciitis for a period of up to 180 days. |
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A randomized study comparing the effect of platelet-rich plasma and platelet-poor plasma for the treatment of plantar fasciitisEnsayo aleatorizado que compara el efecto del plasma rico en plaquetas y el plasma pobre en plaquetas para el tratamiento de la fascitis plantarEstudo aleatório comparando o efeito do plasma rico e plasma pobre em plaquetas para o tratamento de fasciitis plantarPlantar FasciitisPainPlatelet-rich plasma.Fascite plantarDolorPlasma rico en plaquetas.Fascite plantarDorPlasma rico em plaquetas.Objective: To verify the effectiveness of therapy with platelet-rich plasma (PRP) in patients with plantar fasciitis, this prospective, longitudinal, double-blind study was carried out. Methodology: Twenty-three participants with chronic plantar fasciitis aged > 20 years, already treated with conventional methods were included. Participants were randomly divided into platelet-poor plasma (PPP) and platelet-rich plasma (PRP) groups. Double centrifugation was carried out to prepare the platelets samples and two millilitres of PPP (supernatant fraction) or PRP (sediment fraction) were mixed with 1mL of 2% calcium gluconate solution and injected in the plantar fascia, as a single dose. A follow-up at 15 days and then every 60 days up to 180 days of application was carried out and a visual analogue scale (VAS) for pain assessment and the quality-of-life scale validated by the American Orthopedic Foot and Ankle Society (AOFAS) were used to measure the outcomes. Results: A reduction in pain (VAS 8 to 4), in both groups, was seen in the first 15 days and remained up to the 6th month after the application of plasmas, however, no difference was observed between the groups. No significant improvement was observed in the quality of life of the patients. Conclusion: PPP or PRP were able to reduce the VAS, but the presence of platelets did not have a role in the pain relief. Other factors in the plasma may play a role in reducing the pain caused by plantar fasciitis for a period of up to 180 days.Objetivo: para verificar la efectividad de la terapia con plasma rico en plaquetas (PRP) en pacientes con fascitis plantar, se realizó este estudio prospectivo, longitudinal, doble ciego. Metodología: Se incluyeron 23 participantes con fascitis plantar crónica mayores de 20 años, ya tratados con métodos convencionales. Los participantes se dividieron aleatoriamente en grupos de plasma pobre en plaquetas (PPP) y plasma rico en plaquetas (PRP). Se realizó una doble centrifugación para preparar las muestras de plaquetas y se mezclaron dos mililitros de PPP (fracción sobrenadante) o PRP (fracción de sedimento) con 1mL de solución de gluconato de calcio al 2% y se inyectaron en la fascia plantar, en dosis única. Se realizó un seguimiento a los 15 días y luego cada 60 días hasta los 180 días de aplicación y se aplicaron escalas analógicas visuales (EVA) para la evaluación del dolor y la escala de calidad de vida validada por la American Orthopaedic Foot and Ankle Society (AOFAS) utilizado para medir los resultados. Resultados: Se observó una reducción del dolor (EVA 8 para 4), en ambos grupos, en los primeros 15 días y se mantuvo hasta el 6° mes después de la aplicación de los plasmas, sin embargo, no se observó diferencia entre los grupos e también no se observó una mejora significativa en la calidad de vida de los pacientes. Conclusión: PPP o PRP fueron capaces de reducir la EVA, pero la presencia de plaquetas no tuvo un papel en el alivio del dolor. Otros factores en el plasma pueden desempeñar un papel en la reducción del dolor causado por la fascitis plantar durante un período de hasta 180 días.Objetivo: para verificar a eficácia da terapia com plasma rico em plaquetas (PRP) em pacientes com fascite plantar, foi realizado este estudo prospectivo, longitudinal e duplo-cego. Metodologia: Foram incluídos 23 participantes com fascite plantar crônica com idade > 20 anos, já tratados com métodos convencionais. Os participantes foram divididos, aleatoriamente, em grupos de plasma pobre em plaquetas (PPP) e plasma rico em plaquetas (PRP). Dupla centrifugação foi realizada para preparo das amostras de plaquetas e dois mililitros de PPP (fração sobrenadante) ou PRP (fração sedimentar) foram misturados a 1mL de solução de gluconato de cálcio 2% e injetados na fáscia plantar, em dose única. Foi realizado um acompanhamento aos 15 dias e depois a cada 60 dias até 180 dias de aplicação e foram aplicadas as escalas visuais analógicas (EVA) para avaliação da dor e a escala de qualidade de vida validada pela American Orthopaedic Foot and Ankle Society (AOFAS). usados para medir os resultados. Resultados: Houve redução da dor (EVA 8 para 4), em ambos os grupos, nos primeiros 15 dias e permaneceu até o 6º mês após a aplicação dos plasmas, porém não foi observada diferença entre os grupos. Não houve melhora significativa na qualidade de vida dos pacientes. Conclusão: PPP ou PRP foram capazes de reduzir a EVA, mas a presença de plaquetas não teve papel no alívio da dor. Outros fatores no plasma podem desempenhar um papel na redução da dor causada pela fascite plantar por um período de até 180 dias.Research, Society and Development2023-09-16info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/4316810.33448/rsd-v12i9.43168Research, Society and Development; Vol. 12 No. 9; e7812943168Research, Society and Development; Vol. 12 Núm. 9; e7812943168Research, Society and Development; v. 12 n. 9; e78129431682525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/43168/34822Copyright (c) 2023 Elcio Valotto-Junior; Sandra Bin Silva; Luis Henrique Garcia Muniz; Fernanda Ferreira Evangelista; Luciano Henrique Gazoni Scremin; Elisabete Mitiko Kobayashi; Elza Kimurahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessValotto-Junior, ElcioSilva, Sandra BinMuniz, Luis Henrique Garcia Evangelista, Fernanda Ferreira Scremin, Luciano Henrique Gazoni Kobayashi, Elisabete MitikoKimura, Elza2023-10-01T10:43:32Zoai:ojs.pkp.sfu.ca:article/43168Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2023-10-01T10:43:32Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
A randomized study comparing the effect of platelet-rich plasma and platelet-poor plasma for the treatment of plantar fasciitis Ensayo aleatorizado que compara el efecto del plasma rico en plaquetas y el plasma pobre en plaquetas para el tratamiento de la fascitis plantar Estudo aleatório comparando o efeito do plasma rico e plasma pobre em plaquetas para o tratamento de fasciitis plantar |
title |
A randomized study comparing the effect of platelet-rich plasma and platelet-poor plasma for the treatment of plantar fasciitis |
spellingShingle |
A randomized study comparing the effect of platelet-rich plasma and platelet-poor plasma for the treatment of plantar fasciitis Valotto-Junior, Elcio Plantar Fasciitis Pain Platelet-rich plasma. Fascite plantar Dolor Plasma rico en plaquetas. Fascite plantar Dor Plasma rico em plaquetas. |
title_short |
A randomized study comparing the effect of platelet-rich plasma and platelet-poor plasma for the treatment of plantar fasciitis |
title_full |
A randomized study comparing the effect of platelet-rich plasma and platelet-poor plasma for the treatment of plantar fasciitis |
title_fullStr |
A randomized study comparing the effect of platelet-rich plasma and platelet-poor plasma for the treatment of plantar fasciitis |
title_full_unstemmed |
A randomized study comparing the effect of platelet-rich plasma and platelet-poor plasma for the treatment of plantar fasciitis |
title_sort |
A randomized study comparing the effect of platelet-rich plasma and platelet-poor plasma for the treatment of plantar fasciitis |
author |
Valotto-Junior, Elcio |
author_facet |
Valotto-Junior, Elcio Silva, Sandra Bin Muniz, Luis Henrique Garcia Evangelista, Fernanda Ferreira Scremin, Luciano Henrique Gazoni Kobayashi, Elisabete Mitiko Kimura, Elza |
author_role |
author |
author2 |
Silva, Sandra Bin Muniz, Luis Henrique Garcia Evangelista, Fernanda Ferreira Scremin, Luciano Henrique Gazoni Kobayashi, Elisabete Mitiko Kimura, Elza |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Valotto-Junior, Elcio Silva, Sandra Bin Muniz, Luis Henrique Garcia Evangelista, Fernanda Ferreira Scremin, Luciano Henrique Gazoni Kobayashi, Elisabete Mitiko Kimura, Elza |
dc.subject.por.fl_str_mv |
Plantar Fasciitis Pain Platelet-rich plasma. Fascite plantar Dolor Plasma rico en plaquetas. Fascite plantar Dor Plasma rico em plaquetas. |
topic |
Plantar Fasciitis Pain Platelet-rich plasma. Fascite plantar Dolor Plasma rico en plaquetas. Fascite plantar Dor Plasma rico em plaquetas. |
description |
Objective: To verify the effectiveness of therapy with platelet-rich plasma (PRP) in patients with plantar fasciitis, this prospective, longitudinal, double-blind study was carried out. Methodology: Twenty-three participants with chronic plantar fasciitis aged > 20 years, already treated with conventional methods were included. Participants were randomly divided into platelet-poor plasma (PPP) and platelet-rich plasma (PRP) groups. Double centrifugation was carried out to prepare the platelets samples and two millilitres of PPP (supernatant fraction) or PRP (sediment fraction) were mixed with 1mL of 2% calcium gluconate solution and injected in the plantar fascia, as a single dose. A follow-up at 15 days and then every 60 days up to 180 days of application was carried out and a visual analogue scale (VAS) for pain assessment and the quality-of-life scale validated by the American Orthopedic Foot and Ankle Society (AOFAS) were used to measure the outcomes. Results: A reduction in pain (VAS 8 to 4), in both groups, was seen in the first 15 days and remained up to the 6th month after the application of plasmas, however, no difference was observed between the groups. No significant improvement was observed in the quality of life of the patients. Conclusion: PPP or PRP were able to reduce the VAS, but the presence of platelets did not have a role in the pain relief. Other factors in the plasma may play a role in reducing the pain caused by plantar fasciitis for a period of up to 180 days. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-09-16 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/43168 10.33448/rsd-v12i9.43168 |
url |
https://rsdjournal.org/index.php/rsd/article/view/43168 |
identifier_str_mv |
10.33448/rsd-v12i9.43168 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/43168/34822 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 12 No. 9; e7812943168 Research, Society and Development; Vol. 12 Núm. 9; e7812943168 Research, Society and Development; v. 12 n. 9; e7812943168 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052630281748480 |