Review on liquid chromatography coupled with mass spectrometry applied to food toxicological analysis

Detalhes bibliográficos
Autor(a) principal: Tolentino Júnior, Dilceu Silveira
Data de Publicação: 2021
Outros Autores: Santos, Sandra Neres, Marques, Arlanjo Bispo de Sousa, Farias, Kleise Pinheiro, Souza, André Barbosa, Lima, Gracielly Nascimento, Rodrigues, Jairo Lisboa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/15419
Resumo: High performance liquid chromatography (HPLC) coupled with mass spectrometry (MS) is one of the most important analytical techniques used in the determination of non-volatile or thermally unstable compounds. The combination of both unites the excellence of the separation of the analyte of interest in the matrix through the high performance liquid chromatography technique, together with the mass spectrometry technique that confirms the chemical identification. Among the available alternatives, mass spectrometry is the one that best provides the necessary structural information. The coupling between these two techniques gives rise to a robust, versatile and great potential analytical tool in the qualitative and quantitative analysis in food toxicology. This article presents a literature review that aims to present the fundamentals of the application of the coupling of Liquid Chromatography and Mass Spectrometry in the area of food analysis.
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spelling Review on liquid chromatography coupled with mass spectrometry applied to food toxicological analysisRevisión de la cromatografía líquida acoplado con la espectrometría de masas aplicada al análisis toxicológico de los alimentosRevisão sobre cromatografia líquida acoplada à espectrometria de massas aplicada à análise toxicológica de alimentosCromatografia líquidaHPLCEspectrometria de massasCL/EMToxicologiaAlimentos.Cromatografía líquidaHPLCEspectrometría de masasCL/EMToxicologíaAlimentos.Liquid chromatographyHPLCMass spectrometryToxicologyLC/MSFoods.High performance liquid chromatography (HPLC) coupled with mass spectrometry (MS) is one of the most important analytical techniques used in the determination of non-volatile or thermally unstable compounds. The combination of both unites the excellence of the separation of the analyte of interest in the matrix through the high performance liquid chromatography technique, together with the mass spectrometry technique that confirms the chemical identification. Among the available alternatives, mass spectrometry is the one that best provides the necessary structural information. The coupling between these two techniques gives rise to a robust, versatile and great potential analytical tool in the qualitative and quantitative analysis in food toxicology. This article presents a literature review that aims to present the fundamentals of the application of the coupling of Liquid Chromatography and Mass Spectrometry in the area of food analysis.La cromatografía líquida de alta resolución (HPLC) junto con la espectrometría de masas (EM) es una de las técnicas analíticas más importantes utilizadas en la determinación de compuestos no volátiles o térmicamente inestables. La combinación de ambos une la excelencia de la separación del analito de interés en la matriz mediante la técnica de cromatografía líquida de alta resolución, junto con la técnica de espectrometría de masas que confirma la identificación química. Entre las alternativas disponibles, la espectrometría de masas es la que mejor aporta la información estructural necesaria. El acoplamiento entre estas dos técnicas da lugar a una herramienta analítica robusta, versátil y de gran potencial en el análisis cualitativo y cuantitativo en toxicología alimentaria. Este artículo presenta una revisión de la literatura que tiene como objetivo presentar los fundamentos de la aplicación del acoplamiento de la cromatografía líquida y la espectrometría de masas en el área del análisis de alimentos.A cromatografia líquida de alta eficiência (HPLC) acoplada à espectrometria de massas (EM) constitui-se como uma das mais importantes técnicas analíticas utilizadas na determinação de compostos não voláteis ou instáveis termicamente. A combinação de ambas une a excelência da separação do analito de interesse na matriz através da técnica da cromatografia líquida de alto desempenho, juntamente com a técnica da espectrometria de massas que confirma a identificação química. Dentre as alternativas disponíveis, a espectrometria de massas é a que melhor fornece as informações estruturais necessárias. O acoplamento entre estas duas técnicas dá origem a uma ferramenta analítica robusta, versátil e de grande potencial na análise qualitativa e quantitativa em toxicologia de alimentos. O presente artigo apresenta uma revisão de literatura que tem o objetivo de apresentar os fundamentos da aplicação do acoplamento da Cromatografia Líquida e Espectrometria de Massas na área de análise de alimentos.Research, Society and Development2021-05-14info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1541910.33448/rsd-v10i5.15419Research, Society and Development; Vol. 10 No. 5; e47910515419Research, Society and Development; Vol. 10 Núm. 5; e47910515419Research, Society and Development; v. 10 n. 5; e479105154192525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/15419/13613Copyright (c) 2021 Dilceu Silveira Tolentino Júnior; Sandra Neres Santos; Arlanjo Bispo de Sousa Marques; Kleise Pinheiro Farias; André Barbosa Souza; Gracielly Nascimento Lima; Jairo Lisboa Rodrigueshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessTolentino Júnior, Dilceu Silveira Santos, Sandra NeresMarques, Arlanjo Bispo de SousaFarias, Kleise PinheiroSouza, André BarbosaLima, Gracielly NascimentoRodrigues, Jairo Lisboa2021-05-17T18:20:49Zoai:ojs.pkp.sfu.ca:article/15419Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:36:14.786073Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Review on liquid chromatography coupled with mass spectrometry applied to food toxicological analysis
Revisión de la cromatografía líquida acoplado con la espectrometría de masas aplicada al análisis toxicológico de los alimentos
Revisão sobre cromatografia líquida acoplada à espectrometria de massas aplicada à análise toxicológica de alimentos
title Review on liquid chromatography coupled with mass spectrometry applied to food toxicological analysis
spellingShingle Review on liquid chromatography coupled with mass spectrometry applied to food toxicological analysis
Tolentino Júnior, Dilceu Silveira
Cromatografia líquida
HPLC
Espectrometria de massas
CL/EM
Toxicologia
Alimentos.
Cromatografía líquida
HPLC
Espectrometría de masas
CL/EM
Toxicología
Alimentos.
Liquid chromatography
HPLC
Mass spectrometry
Toxicology
LC/MS
Foods.
title_short Review on liquid chromatography coupled with mass spectrometry applied to food toxicological analysis
title_full Review on liquid chromatography coupled with mass spectrometry applied to food toxicological analysis
title_fullStr Review on liquid chromatography coupled with mass spectrometry applied to food toxicological analysis
title_full_unstemmed Review on liquid chromatography coupled with mass spectrometry applied to food toxicological analysis
title_sort Review on liquid chromatography coupled with mass spectrometry applied to food toxicological analysis
author Tolentino Júnior, Dilceu Silveira
author_facet Tolentino Júnior, Dilceu Silveira
Santos, Sandra Neres
Marques, Arlanjo Bispo de Sousa
Farias, Kleise Pinheiro
Souza, André Barbosa
Lima, Gracielly Nascimento
Rodrigues, Jairo Lisboa
author_role author
author2 Santos, Sandra Neres
Marques, Arlanjo Bispo de Sousa
Farias, Kleise Pinheiro
Souza, André Barbosa
Lima, Gracielly Nascimento
Rodrigues, Jairo Lisboa
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Tolentino Júnior, Dilceu Silveira
Santos, Sandra Neres
Marques, Arlanjo Bispo de Sousa
Farias, Kleise Pinheiro
Souza, André Barbosa
Lima, Gracielly Nascimento
Rodrigues, Jairo Lisboa
dc.subject.por.fl_str_mv Cromatografia líquida
HPLC
Espectrometria de massas
CL/EM
Toxicologia
Alimentos.
Cromatografía líquida
HPLC
Espectrometría de masas
CL/EM
Toxicología
Alimentos.
Liquid chromatography
HPLC
Mass spectrometry
Toxicology
LC/MS
Foods.
topic Cromatografia líquida
HPLC
Espectrometria de massas
CL/EM
Toxicologia
Alimentos.
Cromatografía líquida
HPLC
Espectrometría de masas
CL/EM
Toxicología
Alimentos.
Liquid chromatography
HPLC
Mass spectrometry
Toxicology
LC/MS
Foods.
description High performance liquid chromatography (HPLC) coupled with mass spectrometry (MS) is one of the most important analytical techniques used in the determination of non-volatile or thermally unstable compounds. The combination of both unites the excellence of the separation of the analyte of interest in the matrix through the high performance liquid chromatography technique, together with the mass spectrometry technique that confirms the chemical identification. Among the available alternatives, mass spectrometry is the one that best provides the necessary structural information. The coupling between these two techniques gives rise to a robust, versatile and great potential analytical tool in the qualitative and quantitative analysis in food toxicology. This article presents a literature review that aims to present the fundamentals of the application of the coupling of Liquid Chromatography and Mass Spectrometry in the area of food analysis.
publishDate 2021
dc.date.none.fl_str_mv 2021-05-14
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/15419
10.33448/rsd-v10i5.15419
url https://rsdjournal.org/index.php/rsd/article/view/15419
identifier_str_mv 10.33448/rsd-v10i5.15419
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/15419/13613
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 5; e47910515419
Research, Society and Development; Vol. 10 Núm. 5; e47910515419
Research, Society and Development; v. 10 n. 5; e47910515419
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052785553833984

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