Thyroid cancer bios signaling

Detalhes bibliográficos
Autor(a) principal: Garcia, Amanda Carvalho
Data de Publicação: 2022
Outros Autores: Cavalcanti , Teresa Cristina, Collaço , Luiz Martins, Graf, Hans
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/26619
Resumo: Thyroid cancer integrates subtypes that are involved in signaling pathways that result in biological activities, such as differentiation, proliferation, in the absence of disease, and cell survival. BRAF is a gene that encodes the protein kinase\threonine that integrates the MAPK\ERK signaling pathway, as RAF signals are activated by the MAPK\ERK kinase and activates ERK\receptors. The current integrative review addresses the concepts of biosignaling mechanisms involved in thyroid cancer. The methodology used was based on reviewing the contextual principles of signaling that occurs in types of thyroid cancer, such as epidemiological, etiological and physiological factors. This integrative literature review aims to update and show the importance of understanding the biosignaling of thyroid cancer, which aims to highlight the role of genes involved in each type of malignant thyroid neoplasm. studies provide the engagement creation of genetic mutation profile panels, which evidence scientific factors that help in understanding the etiological complexity of thyroid cancer.
id UNIFEI_a0c547718894a5e9a334cedebde45c54
oai_identifier_str oai:ojs.pkp.sfu.ca:article/26619
network_acronym_str UNIFEI
network_name_str Research, Society and Development
repository_id_str
spelling Thyroid cancer bios signalingSeñalización del bios del cáncer de tiroidesBiossinalização do câncer de tireoideCáncerTiroidesMAPKSeñalizaciónBRAF.BiossinalizaçãoCâncerTireoideMAPKBRAF.SinalizaçãoCancerMAPKThyroidBRAF.Thyroid cancer integrates subtypes that are involved in signaling pathways that result in biological activities, such as differentiation, proliferation, in the absence of disease, and cell survival. BRAF is a gene that encodes the protein kinase\threonine that integrates the MAPK\ERK signaling pathway, as RAF signals are activated by the MAPK\ERK kinase and activates ERK\receptors. The current integrative review addresses the concepts of biosignaling mechanisms involved in thyroid cancer. The methodology used was based on reviewing the contextual principles of signaling that occurs in types of thyroid cancer, such as epidemiological, etiological and physiological factors. This integrative literature review aims to update and show the importance of understanding the biosignaling of thyroid cancer, which aims to highlight the role of genes involved in each type of malignant thyroid neoplasm. studies provide the engagement creation of genetic mutation profile panels, which evidence scientific factors that help in understanding the etiological complexity of thyroid cancer.El cáncer de tiroides integra subtipos que están involucrados en vías de señalización que dan como resultado actividades biológicas, como diferenciación, proliferación, en ausencia de enfermedad y supervivencia celular. BRAF es un gen que codifica la proteína quinasa\treonina que integra la vía de señalización MAPK\ERK, ya que las señales RAF son activadas por la quinasa MAPK\ERK y activa los receptores ERK. La revisión integradora actual aborda los conceptos de los mecanismos de bioseñalización involucrados en el cáncer de tiroides. La metodología utilizada se basó en revisar los principios contextuales de señalización que se dan en los tipos de cáncer de tiroides, como son los factores epidemiológicos, etiológicos y fisiológicos. Esta revisión integrativa de la literatura tiene como objetivo actualizar y mostrar la importancia de comprender la bioseñalización del cáncer de tiroides, que tiene como objetivo resaltar el papel de los genes involucrados en cada tipo de neoplasia maligna de tiroides. Los estudios brindan la participación en la creación de paneles de perfiles de mutaciones genéticas, que evidencian factores científicos que ayudan a comprender la complejidad etiológica del cáncer de tiroides.Câncer de tireoide integra subtipos que estão envolvidos em vias sinalização que resultam nas atividades biológicas, como diferenciação, proliferação, na ausência de doença e sobrevida celular. O BRAF é um gene que codifica a proteína quinase\treonina que integra a via de sinalização MAPK\ERK, pois sinais RAF são ativados pela quinase MAPK\ERK e ativa ERK\receptores. Na revisão integrativa atual aborda os conceitos dos mecanismos da biossinalização envolvidos no cancer de tireoide. A metologia utilizada fundamentou-se em revisar os princípios contextuais da sinalização que ocorre nos tipos de câncer de tireoide, como os fatores epidemiológicos, etiológicos e fisiológicos. Esta revisão integrativa da literatura objetiva atualizar e mostrar a importância da compreensão sobre a biossinalização do câncer de tireoide, que visa destacar o papel dos genes envolvidos em cada tipo de neoplasia maligna da tireoide. estudos proporcionam o engajamento criação de paneis de perfil de mutação genética, que evidencia fatores científicos que ajudem na compreensão da complexidade etiológica do câncer de tireoide.Research, Society and Development2022-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2661910.33448/rsd-v11i3.26619Research, Society and Development; Vol. 11 No. 3; e41811326619Research, Society and Development; Vol. 11 Núm. 3; e41811326619Research, Society and Development; v. 11 n. 3; e418113266192525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/26619/23387Copyright (c) 2022 Amanda Carvalho Garcia; Teresa Cristina Cavalcanti ; Luiz Martins Collaço ; Hans Grafhttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessGarcia, Amanda Carvalho Cavalcanti , Teresa Cristina Collaço , Luiz Martins Graf, Hans2022-03-09T13:44:38Zoai:ojs.pkp.sfu.ca:article/26619Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:36.874119Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Thyroid cancer bios signaling
Señalización del bios del cáncer de tiroides
Biossinalização do câncer de tireoide
title Thyroid cancer bios signaling
spellingShingle Thyroid cancer bios signaling
Garcia, Amanda Carvalho
Cáncer
Tiroides
MAPK
Señalización
BRAF.
Biossinalização
Câncer
Tireoide
MAPK
BRAF.
Sinalização
Cancer
MAPK
Thyroid
BRAF.
title_short Thyroid cancer bios signaling
title_full Thyroid cancer bios signaling
title_fullStr Thyroid cancer bios signaling
title_full_unstemmed Thyroid cancer bios signaling
title_sort Thyroid cancer bios signaling
author Garcia, Amanda Carvalho
author_facet Garcia, Amanda Carvalho
Cavalcanti , Teresa Cristina
Collaço , Luiz Martins
Graf, Hans
author_role author
author2 Cavalcanti , Teresa Cristina
Collaço , Luiz Martins
Graf, Hans
author2_role author
author
author
dc.contributor.author.fl_str_mv Garcia, Amanda Carvalho
Cavalcanti , Teresa Cristina
Collaço , Luiz Martins
Graf, Hans
dc.subject.por.fl_str_mv Cáncer
Tiroides
MAPK
Señalización
BRAF.
Biossinalização
Câncer
Tireoide
MAPK
BRAF.
Sinalização
Cancer
MAPK
Thyroid
BRAF.
topic Cáncer
Tiroides
MAPK
Señalización
BRAF.
Biossinalização
Câncer
Tireoide
MAPK
BRAF.
Sinalização
Cancer
MAPK
Thyroid
BRAF.
description Thyroid cancer integrates subtypes that are involved in signaling pathways that result in biological activities, such as differentiation, proliferation, in the absence of disease, and cell survival. BRAF is a gene that encodes the protein kinase\threonine that integrates the MAPK\ERK signaling pathway, as RAF signals are activated by the MAPK\ERK kinase and activates ERK\receptors. The current integrative review addresses the concepts of biosignaling mechanisms involved in thyroid cancer. The methodology used was based on reviewing the contextual principles of signaling that occurs in types of thyroid cancer, such as epidemiological, etiological and physiological factors. This integrative literature review aims to update and show the importance of understanding the biosignaling of thyroid cancer, which aims to highlight the role of genes involved in each type of malignant thyroid neoplasm. studies provide the engagement creation of genetic mutation profile panels, which evidence scientific factors that help in understanding the etiological complexity of thyroid cancer.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/26619
10.33448/rsd-v11i3.26619
url https://rsdjournal.org/index.php/rsd/article/view/26619
identifier_str_mv 10.33448/rsd-v11i3.26619
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/26619/23387
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 3; e41811326619
Research, Society and Development; Vol. 11 Núm. 3; e41811326619
Research, Society and Development; v. 11 n. 3; e41811326619
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052705528610816

Registros relacionados