Bibliographic survey of the mechanism of development of Type II Diabetes Mellitus after infection by SARS-COV-2

• Autor(a) principal: Carvalho, Felipe dos Santos
• Data de Publicação: 2022
• Outros Autores: Machado, Eliza Caetano, Leitão, Agnaldo Saraiva, Ramos, Dandara Franco, Oliveira, Laís Túlio, Lima , Ana Julia Aidar, Mendes, Guilherme Stephano Moreira
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Research, Society and Development
• Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/33999
• topic: Diabetes mellitus tipo II; SARS-COV-2; Disfunción metabólica de la glucosa.; Diabetes mellitus tipo II; SARS-CoV-2; Disfunção metabólica glicose.; Diabetes mellitus type II; SARS-COV-2; Metabolic glucose dysfunction.

This study aims to conduct a systematic review of the literature to understand the mechanism of development of type II DM after SARS-COV-2 infection and to point out new updates on the subject. Currently, the world faces the pandemic of Coronavirus Disease 2019, a severe acute respiratory syndrome caused by coronavirus SARS-COV-2, having as one of the most frequent pathological consequences diabetes mellitus type II (Type II DM). DM type II is a metabolic endocrine dysfunction characterized by excess circulating glucose in the blood due to defects in the secretion and/or action of insulin, thus hindering the use of glucose as an energy source for the homeostatic metabolic functions of the human body. To date, several epidemiological studies indicate that a high pathological relationship between Covid-19 and DM type II where both pathologies complement each other to generate simultaneous harmful damage. By bringing pancreatic beta cell dysfunction, SARS-COV-2 can induce transient acute hyperglycemia or lead to a genetically predisposed individual developing DM type II. The prevalence of DM type II in patients recovering from post-covid 19 infection is notorious, but new searches to better understand its etiology are crucial.