Dermatological toxicity associated with the use of chemotherapy: hand foot syndrome an integrative approach
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/20501 |
Resumo: | The objective was to identify the development of Hand-Foot Syndrome in the literature, as an adverse effect of the use of chemotherapy. Integrative review performed in LILACS, BDENF, PubMed and ScienceDirect databases, in Portuguese, English and Spanish. Clinical trials published with a time frame from 2016 to 2021 centered on the adult audience were selected and segregated into two topics. The information was tabulated in Microsoft Excel® 2010 program and processed based on the strategy: simple descriptive arithmetic mean, absolute and relative frequency. A total of 559 articles were found, after applying the inclusion and exclusion criteria, 20 studies were chosen to compose the final sample. The pharmacological class most listed as a potentiator of SMP was fluoropyrimidines (80%). Through the clinical manifestations presented in the syndrome, negative impacts perpetuate the routine of patients, as the performance of activities of daily living is compromised, to minimize the damage caused by this condition, therapeutic methods were highlighted, these are applied to reduce the degrees of the syndrome and better quality of life. In summary, it is clear that the use of chemotherapy increases overall and disease-free survival, however it causes some recurrent adverse reactions, including the Hand-Foot Syndrome, its manifestations are not life-threatening, but the limitations triggered infer damages to the self-care and quality of life becomes unsatisfactory. |
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Dermatological toxicity associated with the use of chemotherapy: hand foot syndrome an integrative approachToxicidad dermatológica asociada con el uso de quimioterapias: síndrome de mano-pie un enfoque integrativoToxicidade dermatológica associada ao uso de quimioterápicos: síndrome mão – pé uma abordagem integrativaCâncerQuimioterapiaSíndrome mão-pé.CáncerQuimioterapiaSíndrome mano-pie.CancerChemotherapyHand foot syndrome.The objective was to identify the development of Hand-Foot Syndrome in the literature, as an adverse effect of the use of chemotherapy. Integrative review performed in LILACS, BDENF, PubMed and ScienceDirect databases, in Portuguese, English and Spanish. Clinical trials published with a time frame from 2016 to 2021 centered on the adult audience were selected and segregated into two topics. The information was tabulated in Microsoft Excel® 2010 program and processed based on the strategy: simple descriptive arithmetic mean, absolute and relative frequency. A total of 559 articles were found, after applying the inclusion and exclusion criteria, 20 studies were chosen to compose the final sample. The pharmacological class most listed as a potentiator of SMP was fluoropyrimidines (80%). Through the clinical manifestations presented in the syndrome, negative impacts perpetuate the routine of patients, as the performance of activities of daily living is compromised, to minimize the damage caused by this condition, therapeutic methods were highlighted, these are applied to reduce the degrees of the syndrome and better quality of life. In summary, it is clear that the use of chemotherapy increases overall and disease-free survival, however it causes some recurrent adverse reactions, including the Hand-Foot Syndrome, its manifestations are not life-threatening, but the limitations triggered infer damages to the self-care and quality of life becomes unsatisfactory.El objetivo fue identificar el desarrollo del Síndrome Mano-Pie en la literatura, como efecto adverso del uso de quimioterapia. Revisión integrativa realizada en las bases de datos LILACS, BDENF, PubMed y ScienceDirect, en portugués, inglés y español. Los ensayos clínicos publicados con un período de tiempo de 2016 a 2021 centrados en la audiencia adulta fueron seleccionados y segregados en dos temas. La información se tabuló en el programa Microsoft Excel® 2010 y se procesó con base en la estrategia: media aritmética descriptiva simple, frecuencia absoluta y relativa. Se encontraron un total de 559 artículos, luego de aplicar los criterios de inclusión y exclusión, se eligieron 20 estudios para componer la muestra final. La clase farmacológica más enumerada como potenciador de la SMP fueron las fluoropirimidinas (80%). A través de las manifestaciones clínicas que presenta el síndrome, los impactos negativos perpetúan la rutina de los pacientes, ya que se compromete el desempeño de las actividades de la vida diaria, para minimizar el daño causado por esta condición, se destacaron los métodos terapéuticos, estos se aplican para reducir los grados de el síndrome y una mejor calidad de vida. En resumen, es claro que el uso de quimioterapia aumenta la supervivencia global y libre de enfermedad, sin embargo provoca algunas reacciones adversas recurrentes, entre ellas el Síndrome Mano-Pie, sus manifestaciones no ponen en riesgo la vida, pero las limitaciones desencadenadas infieren daños a la el autocuidado y la calidad de vida se vuelven insatisfactorios.Objetivou-se identificar na literatura o desenvolvimento da Síndrome Mão-Pé, como efeito adverso à utilização de quimioterápicos. Revisão integrativa realizada nas bases de dados LILACS, BDENF, PubMed e na biblioteca virtual ScienceDirect, nos idiomas português, inglês e espanhol. Ensaios clínicos publicados com recorte temporal de 2016 a 2021, centrados no público adulto, foram selecionados e segregados em dois tópicos. As informações foram tabuladas no programa Microsoft Excel® 2010 e processadas a partir de estratégia: média aritmética descritiva simples, frequência absoluta e relativa. Encontrou-se 559 artigos, após aplicação dos critérios de inclusão e exclusão, 20 estudos foram eleitos para compor a amostra final. A classe farmacológica mais elencada como potencializadora da Síndrome Mão Pé (SMP) foi à fluoropirimidinas (80%). Mediante às manifestações clínicas apresentadas na síndrome, impactos negativos perpetuam na rotina dos pacientes, pois a execução das atividades de vida diária é comprometida, para minimizar os danos causados por esta afecção, métodos terapêuticos foram salientados, estes são aplicados para redução de graus da síndrome e melhor qualidade de vida. Em síntese, percebe-se que, a utilização de quimioterápicos melhora o prognóstico oncológico, entretanto acarreta algumas reações adversas recorrentes, dentre estas, a SMP, cujas manifestações não são ameaçadoras à vida, mas as limitações desencadeadas inferem prejuízos no autocuidado e a qualidade de vida torna-se insatisfatória.Research, Society and Development2021-09-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2050110.33448/rsd-v10i12.20501Research, Society and Development; Vol. 10 No. 12Research, Society and Development; Vol. 10 Núm. 12Research, Society and Development; v. 10 n. 122525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/20501/18466Copyright (c) 2021 Aislayne Rodrigues Valentim; Lays Santos Nascimento; Gustavo Venicius da Silva Santos ; Adão Renato de Jesus Freire ; Priscila Laíse dos Santos; Deyse Mirelle Souza Santoshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessValentim, Aislayne RodriguesNascimento, Lays Santos Santos , Gustavo Venicius da Silva Freire , Adão Renato de Jesus Santos, Priscila Laíse dos Santos, Deyse Mirelle Souza2021-11-14T20:26:51Zoai:ojs.pkp.sfu.ca:article/20501Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:40:07.975031Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Dermatological toxicity associated with the use of chemotherapy: hand foot syndrome an integrative approach Toxicidad dermatológica asociada con el uso de quimioterapias: síndrome de mano-pie un enfoque integrativo Toxicidade dermatológica associada ao uso de quimioterápicos: síndrome mão – pé uma abordagem integrativa |
title |
Dermatological toxicity associated with the use of chemotherapy: hand foot syndrome an integrative approach |
spellingShingle |
Dermatological toxicity associated with the use of chemotherapy: hand foot syndrome an integrative approach Valentim, Aislayne Rodrigues Câncer Quimioterapia Síndrome mão-pé. Cáncer Quimioterapia Síndrome mano-pie. Cancer Chemotherapy Hand foot syndrome. |
title_short |
Dermatological toxicity associated with the use of chemotherapy: hand foot syndrome an integrative approach |
title_full |
Dermatological toxicity associated with the use of chemotherapy: hand foot syndrome an integrative approach |
title_fullStr |
Dermatological toxicity associated with the use of chemotherapy: hand foot syndrome an integrative approach |
title_full_unstemmed |
Dermatological toxicity associated with the use of chemotherapy: hand foot syndrome an integrative approach |
title_sort |
Dermatological toxicity associated with the use of chemotherapy: hand foot syndrome an integrative approach |
author |
Valentim, Aislayne Rodrigues |
author_facet |
Valentim, Aislayne Rodrigues Nascimento, Lays Santos Santos , Gustavo Venicius da Silva Freire , Adão Renato de Jesus Santos, Priscila Laíse dos Santos, Deyse Mirelle Souza |
author_role |
author |
author2 |
Nascimento, Lays Santos Santos , Gustavo Venicius da Silva Freire , Adão Renato de Jesus Santos, Priscila Laíse dos Santos, Deyse Mirelle Souza |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Valentim, Aislayne Rodrigues Nascimento, Lays Santos Santos , Gustavo Venicius da Silva Freire , Adão Renato de Jesus Santos, Priscila Laíse dos Santos, Deyse Mirelle Souza |
dc.subject.por.fl_str_mv |
Câncer Quimioterapia Síndrome mão-pé. Cáncer Quimioterapia Síndrome mano-pie. Cancer Chemotherapy Hand foot syndrome. |
topic |
Câncer Quimioterapia Síndrome mão-pé. Cáncer Quimioterapia Síndrome mano-pie. Cancer Chemotherapy Hand foot syndrome. |
description |
The objective was to identify the development of Hand-Foot Syndrome in the literature, as an adverse effect of the use of chemotherapy. Integrative review performed in LILACS, BDENF, PubMed and ScienceDirect databases, in Portuguese, English and Spanish. Clinical trials published with a time frame from 2016 to 2021 centered on the adult audience were selected and segregated into two topics. The information was tabulated in Microsoft Excel® 2010 program and processed based on the strategy: simple descriptive arithmetic mean, absolute and relative frequency. A total of 559 articles were found, after applying the inclusion and exclusion criteria, 20 studies were chosen to compose the final sample. The pharmacological class most listed as a potentiator of SMP was fluoropyrimidines (80%). Through the clinical manifestations presented in the syndrome, negative impacts perpetuate the routine of patients, as the performance of activities of daily living is compromised, to minimize the damage caused by this condition, therapeutic methods were highlighted, these are applied to reduce the degrees of the syndrome and better quality of life. In summary, it is clear that the use of chemotherapy increases overall and disease-free survival, however it causes some recurrent adverse reactions, including the Hand-Foot Syndrome, its manifestations are not life-threatening, but the limitations triggered infer damages to the self-care and quality of life becomes unsatisfactory. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-09-27 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/20501 10.33448/rsd-v10i12.20501 |
url |
https://rsdjournal.org/index.php/rsd/article/view/20501 |
identifier_str_mv |
10.33448/rsd-v10i12.20501 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/20501/18466 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 12 Research, Society and Development; Vol. 10 Núm. 12 Research, Society and Development; v. 10 n. 12 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052755884376064 |