Mucolytic action of bromelain: an integrative review
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Research, Society and Development |
| Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/21495 |
Resumo: | Bromelain has anti-inflammatory, antioxidant, anti-cancer properties and also works as an aid in the digestion process and as a cardioprotective agent. The aim of the study was to analyze through the scientific literature the mucolytic action of bromelain. This is a literature review of the literature, which was used to generate the guiding question: “What scientific evidence shows the mucolytic action of bromelain?”. Seven studies included in this review, all with a quantitative approach to data (100%); concentrated mainly in the year 2017 (42.9%) and all were in the English language (100%), with origin of studies published in Austria (42.9%), the European Journal of Pharmaceutics and Biopharmaceutics concentrated more publications, corresponding to 28.6%. The studies addressed the use of bromelain associated with other substances, the effects of bromelain, such as improving permeability for drugs, and its action on the intestinal mucus, making it more permeable. The study allowed for the expansion of knowledge about bromelain or bromelain as a mucolytic agent, its nutraceutical potentials and action against some pathologies, in addition to its possible use by the pharmaceutical industry for the creation of drugs that overcome the mucolytic barrier more easily. |
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Mucolytic action of bromelain: an integrative review Acción mucolítica de la bromelina: uma revisión integradoraAção Mucolítica da Bromelina: uma revisão integrativaBromelains; Mucus; Bodily Secretions.BromelainsMucusBodily secretions.Bromelaínas; Moco; Secreciones Corporales.BromelaínasMocoSecreciones corporales.Bromelaína; Muco; Secreções corporais.BromelaínaMucoSecreções corporais.Bromelain has anti-inflammatory, antioxidant, anti-cancer properties and also works as an aid in the digestion process and as a cardioprotective agent. The aim of the study was to analyze through the scientific literature the mucolytic action of bromelain. This is a literature review of the literature, which was used to generate the guiding question: “What scientific evidence shows the mucolytic action of bromelain?”. Seven studies included in this review, all with a quantitative approach to data (100%); concentrated mainly in the year 2017 (42.9%) and all were in the English language (100%), with origin of studies published in Austria (42.9%), the European Journal of Pharmaceutics and Biopharmaceutics concentrated more publications, corresponding to 28.6%. The studies addressed the use of bromelain associated with other substances, the effects of bromelain, such as improving permeability for drugs, and its action on the intestinal mucus, making it more permeable. The study allowed for the expansion of knowledge about bromelain or bromelain as a mucolytic agent, its nutraceutical potentials and action against some pathologies, in addition to its possible use by the pharmaceutical industry for the creation of drugs that overcome the mucolytic barrier more easily.La bromelina tiene propiedades antiinflamatorias, antioxidantes y anticancerígenas y también actúa como ayuda en el proceso de digestión y como agente cardioprotector. El objetivo del estudio fue analizar a través de la literatura científica la acción mucolítica de la bromelina. Se trata de una revisión bibliográfica de la literatura, que se utilizó para generar la pregunta orientadora: “¿Qué evidencia científica muestra la acción mucolítica de la bromelina?”. Siete estudios incluidos en esta revisión, todos con un enfoque cuantitativo de los datos (100%); concentrados principalmente en el año 2017 (42,9%) y todos fueron en lengua inglesa (100%), con origen de estudios publicados en Austria (42,9%), la Revista Europea de Farmacéutica y Biofarmacéutica concentró más publicaciones, correspondiente al 28,6%. Los estudios abordaron el uso de la bromelina asociada a otras sustancias, los efectos de la bromelina, como mejorar la permeabilidad de los fármacos, y su acción sobre el moco intestinal, haciéndolo más permeable. El estudio permitió ampliar el conocimiento sobre la bromelina o bromelina como agente mucolítico, su potencial nutracéutico y acción frente a algunas patologías, además de su posible uso por parte de la industria farmacéutica para la creación de fármacos que superen fácilmente la barrera mucolítica.A bromelina possui um potencial anti-inflamatório, antioxidante, propriedades anticâncer e funciona também como um auxiliador no processo de digestão e como um agente cardioprotetor. O objetivo do estudo foi analisar por meio da literatura científica a ação mucolítica da bromelina. Trata-se de uma pesquisa revisão bibliográfica da literatura, na qual foi utilizada para a geração da questão norteadora: “Quais evidências científicas mostram a ação mucolítica da bromelina?”. Sete estudos incluídos nesta revisão, todos com abordagem quantitativa dos dados (100%); concentraram-se principalmente no ano de 2017 (42,9%) e todos estavam na língua inglesa (100%), com procedência de estudos publicados na Áustria (42,9%), o European Journal of Pharmaceutics and Biopharmaceutics concentrou mais publicações, correspondendo a 28,6%. Os estudos abordavam sobre o uso da bromelina associadas com outras substâncias, os efeitos da bromelina, tais como a melhoria da permeabilidade para fármacos, e sua atuação no muco intestinal tornando-o mais permeável. O estudo permitiu expandir os conhecimentos acerca da bromelina ou bromelaína enquanto agente mucolítico, seus potenciais nutracêuticos e ação contra algumas patologias, além de sua possível utilização pela indústria farmacêutica para a criação de drogas que ultrapassem a barreira mucolítica mais facilmente.Research, Society and Development2021-10-21info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2149510.33448/rsd-v10i13.21495Research, Society and Development; Vol. 10 No. 13; e557101321495Research, Society and Development; Vol. 10 Núm. 13; e557101321495Research, Society and Development; v. 10 n. 13; e5571013214952525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/21495/19224Copyright (c) 2021 Eduardo Henrique Barros Ferreira; Karine Costa Melo; Chrisllayne Oliveira da Silva; Jesineide Sousa da Silva ; Laila da Silva Mota Vilanova; Francisléia Falcão França Santos Siqueira ; Solygardia Albuquerque Maciel Teixeira ; Hálmisson D’Árley Santos Siqueira; Raimundo Nonato Cardoso Miranda Junior; Hádila Giovanna Santos Siqueira Cunha; Jairina Nunes Chaves; Rodolfo Ritchelle Lima dos Santos; Camilla Lohanny Azevedo Viana; Marconny Lira da Silva; Ney Rômulo de Oliveira Paulahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess Ferreira, Eduardo Henrique Barros Melo, Karine Costa Silva, Chrisllayne Oliveira da Silva , Jesineide Sousa da Vilanova, Laila da Silva Mota Siqueira , Francisléia Falcão França Santos Teixeira , Solygardia Albuquerque Maciel Siqueira, Hálmisson D’Árley Santos Miranda Junior, Raimundo Nonato CardosoCunha, Hádila Giovanna Santos SiqueiraChaves, Jairina Nunes Santos, Rodolfo Ritchelle Lima dos Viana, Camilla Lohanny AzevedoSilva, Marconny Lira da Paula, Ney Rômulo de Oliveira 2021-11-21T18:26:28Zoai:ojs.pkp.sfu.ca:article/21495Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:40:53.698105Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
| dc.title.none.fl_str_mv |
Mucolytic action of bromelain: an integrative review Acción mucolítica de la bromelina: uma revisión integradora Ação Mucolítica da Bromelina: uma revisão integrativa |
| title |
Mucolytic action of bromelain: an integrative review |
| spellingShingle |
Mucolytic action of bromelain: an integrative review Ferreira, Eduardo Henrique Barros Bromelains; Mucus; Bodily Secretions. Bromelains Mucus Bodily secretions. Bromelaínas; Moco; Secreciones Corporales. Bromelaínas Moco Secreciones corporales. Bromelaína; Muco; Secreções corporais. Bromelaína Muco Secreções corporais. |
| title_short |
Mucolytic action of bromelain: an integrative review |
| title_full |
Mucolytic action of bromelain: an integrative review |
| title_fullStr |
Mucolytic action of bromelain: an integrative review |
| title_full_unstemmed |
Mucolytic action of bromelain: an integrative review |
| title_sort |
Mucolytic action of bromelain: an integrative review |
| author |
Ferreira, Eduardo Henrique Barros |
| author_facet |
Ferreira, Eduardo Henrique Barros Melo, Karine Costa Silva, Chrisllayne Oliveira da Silva , Jesineide Sousa da Vilanova, Laila da Silva Mota Siqueira , Francisléia Falcão França Santos Teixeira , Solygardia Albuquerque Maciel Siqueira, Hálmisson D’Árley Santos Miranda Junior, Raimundo Nonato Cardoso Cunha, Hádila Giovanna Santos Siqueira Chaves, Jairina Nunes Santos, Rodolfo Ritchelle Lima dos Viana, Camilla Lohanny Azevedo Silva, Marconny Lira da Paula, Ney Rômulo de Oliveira |
| author_role |
author |
| author2 |
Melo, Karine Costa Silva, Chrisllayne Oliveira da Silva , Jesineide Sousa da Vilanova, Laila da Silva Mota Siqueira , Francisléia Falcão França Santos Teixeira , Solygardia Albuquerque Maciel Siqueira, Hálmisson D’Árley Santos Miranda Junior, Raimundo Nonato Cardoso Cunha, Hádila Giovanna Santos Siqueira Chaves, Jairina Nunes Santos, Rodolfo Ritchelle Lima dos Viana, Camilla Lohanny Azevedo Silva, Marconny Lira da Paula, Ney Rômulo de Oliveira |
| author2_role |
author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Ferreira, Eduardo Henrique Barros Melo, Karine Costa Silva, Chrisllayne Oliveira da Silva , Jesineide Sousa da Vilanova, Laila da Silva Mota Siqueira , Francisléia Falcão França Santos Teixeira , Solygardia Albuquerque Maciel Siqueira, Hálmisson D’Árley Santos Miranda Junior, Raimundo Nonato Cardoso Cunha, Hádila Giovanna Santos Siqueira Chaves, Jairina Nunes Santos, Rodolfo Ritchelle Lima dos Viana, Camilla Lohanny Azevedo Silva, Marconny Lira da Paula, Ney Rômulo de Oliveira |
| dc.subject.por.fl_str_mv |
Bromelains; Mucus; Bodily Secretions. Bromelains Mucus Bodily secretions. Bromelaínas; Moco; Secreciones Corporales. Bromelaínas Moco Secreciones corporales. Bromelaína; Muco; Secreções corporais. Bromelaína Muco Secreções corporais. |
| topic |
Bromelains; Mucus; Bodily Secretions. Bromelains Mucus Bodily secretions. Bromelaínas; Moco; Secreciones Corporales. Bromelaínas Moco Secreciones corporales. Bromelaína; Muco; Secreções corporais. Bromelaína Muco Secreções corporais. |
| description |
Bromelain has anti-inflammatory, antioxidant, anti-cancer properties and also works as an aid in the digestion process and as a cardioprotective agent. The aim of the study was to analyze through the scientific literature the mucolytic action of bromelain. This is a literature review of the literature, which was used to generate the guiding question: “What scientific evidence shows the mucolytic action of bromelain?”. Seven studies included in this review, all with a quantitative approach to data (100%); concentrated mainly in the year 2017 (42.9%) and all were in the English language (100%), with origin of studies published in Austria (42.9%), the European Journal of Pharmaceutics and Biopharmaceutics concentrated more publications, corresponding to 28.6%. The studies addressed the use of bromelain associated with other substances, the effects of bromelain, such as improving permeability for drugs, and its action on the intestinal mucus, making it more permeable. The study allowed for the expansion of knowledge about bromelain or bromelain as a mucolytic agent, its nutraceutical potentials and action against some pathologies, in addition to its possible use by the pharmaceutical industry for the creation of drugs that overcome the mucolytic barrier more easily. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021-10-21 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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https://rsdjournal.org/index.php/rsd/article/view/21495 10.33448/rsd-v10i13.21495 |
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https://rsdjournal.org/index.php/rsd/article/view/21495 |
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10.33448/rsd-v10i13.21495 |
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por |
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por |
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https://rsdjournal.org/index.php/rsd/article/view/21495/19224 |
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https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
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https://creativecommons.org/licenses/by/4.0 |
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openAccess |
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application/pdf |
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Research, Society and Development |
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Research, Society and Development |
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Research, Society and Development; Vol. 10 No. 13; e557101321495 Research, Society and Development; Vol. 10 Núm. 13; e557101321495 Research, Society and Development; v. 10 n. 13; e557101321495 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
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